BR0113410A - Dose eletrostática medida - Google Patents

Dose eletrostática medida

Info

Publication number
BR0113410A
BR0113410A BR0113410-8A BR0113410A BR0113410A BR 0113410 A BR0113410 A BR 0113410A BR 0113410 A BR0113410 A BR 0113410A BR 0113410 A BR0113410 A BR 0113410A
Authority
BR
Brazil
Prior art keywords
electrostatic
dose
powder
density
measured
Prior art date
Application number
BR0113410-8A
Other languages
English (en)
Inventor
Thomas Nilsson
Lars-Gunnar Nilsson
Original Assignee
Microdrug Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microdrug Ag filed Critical Microdrug Ag
Publication of BR0113410A publication Critical patent/BR0113410A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Battery Electrode And Active Subsutance (AREA)
  • Electrotherapy Devices (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)

Abstract

"DOSE ELETROSTáTICA MEDIDA". A presente invenção refere-se a uma dose eletrostática e um método e um processo para a obtenção de uma dose eletrostática. A dose eletrostática consiste em um pó medicinal medido e é formada a partir de um pó eletrostático consistindo de uma sustância ativa em pó ou uma formulação medicinal na forma de po seco, que e transferida para sobre um membro do dispositivo que forma um suporte de dose. A dose eletrostática preparada a partir de um pó eletrostático apresenta uma fração de partículas finas (FPF) contendo da ordem de 50% ou mais de seu conteúdo com tamanho de partícula entre 0,5 e 5 <109>m. O pó eletrostático de tal dose eletrostática medida provê ainda propriedades eletrostáticas no que diz respeito à carga específica absoluta por massa após a carga da ordem de 0,1 a 25 <109>C/g, e apresenta uma constante de decaimento de carga Q~ 50~ maior que 0,1 segundos, com uma densidade tap menor que 0,8 g/ml. A porosidade da dose eletrostática é ajustada por meio de vibração mecânica e/ou elétrica do membro do dispositivo recipiente de dose durante, a operação de obtenção da dose eletrostática, para obter-se um valor de porosidade otimizado de 75 a 99,9% calculado como 100-100x (Densidade~ dose-eletrostática~/Densidade~ pó-eletrostático~). O método e o processamento da dose eletrostática são parcialmente ilustrados por um fluxograma no qual as etapas 230 a 270 apresentam os parâmetros necessários que devem ser mantidos sob controle.
BR0113410-8A 2000-08-31 2001-07-27 Dose eletrostática medida BR0113410A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0003082A SE516554C2 (sv) 2000-08-31 2000-08-31 Uppmätt elektrodos
PCT/SE2001/001683 WO2002018000A1 (en) 2000-08-31 2001-07-27 Metered electro-dose

Publications (1)

Publication Number Publication Date
BR0113410A true BR0113410A (pt) 2003-07-29

Family

ID=20280852

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113410-8A BR0113410A (pt) 2000-08-31 2001-07-27 Dose eletrostática medida

Country Status (12)

Country Link
US (1) US6868853B1 (pt)
EP (1) EP1315532A1 (pt)
JP (1) JP2004516046A (pt)
KR (1) KR20030066606A (pt)
CN (1) CN1468121A (pt)
AU (1) AU2001280352A1 (pt)
BR (1) BR0113410A (pt)
CA (1) CA2418039A1 (pt)
PL (1) PL360177A1 (pt)
RU (1) RU2003101911A (pt)
SE (1) SE516554C2 (pt)
WO (1) WO2002018000A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE524957C2 (sv) * 2002-04-12 2004-11-02 Microdrug Ag Förfarande för uppdelning och fördelning i luft av torrt pulvermedikament
SE524990C2 (sv) * 2002-04-12 2004-11-09 Microdrug Ag Preparation av terapeutiskt torrt pulver samt förfarande för uppdelning och spridning i luft av medicinskt pulver
AU2002952683A0 (en) * 2002-11-15 2002-11-28 Commonwealth Scientific And Industrial Research Organisation Apparatus for delivering dry aerosols to the respiratory tract
SE528121C2 (sv) * 2004-03-29 2006-09-05 Mederio Ag Preparering av torrpulver för på förhand uppmätt DPI
ATE501183T1 (de) 2004-10-21 2011-03-15 Basell Polyolefine Gmbh 1-buten-polymer und herstellungsverfahren dafür
US7659725B2 (en) * 2006-03-24 2010-02-09 3M Innovative Properties Company Method for assessing the suitability of metered dose inhaler actuators
NZ576637A (en) 2006-10-25 2012-05-25 Novartis Ag Powder dispersion apparatus with and mediciment receptacles that are cut open using an elliptical arc shaped knife blade oriented to yaw between 4 and 12 degrees
US7958683B2 (en) * 2007-10-04 2011-06-14 Hni Corporation Wall panel system
US9089279B2 (en) 2011-12-29 2015-07-28 General Electric Company Ion-based breath analysis system
EP3212212B1 (en) 2014-10-31 2020-09-23 Monash University Powder formulation
EP3285075A1 (en) * 2016-08-19 2018-02-21 Consejo Superior De Investigaciones Cientificas Device and method for mapping ferroelectric and/or piezoelectric samples

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714007A (en) * 1995-06-06 1998-02-03 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate
SE504458C2 (sv) 1995-06-21 1997-02-17 Lars Gunnar Nilsson Inhalator för elektrisk dosering av substanser
US5694920A (en) 1996-01-25 1997-12-09 Abrams; Andrew L. Inhalation device
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6565885B1 (en) * 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6063194A (en) * 1998-06-10 2000-05-16 Delsys Pharmaceutical Corporation Dry powder deposition apparatus
SE512386C2 (sv) 1998-07-30 2000-03-06 Microdrug Ag Förfarande och anordning för klassificering av elektrostatiskt laddat pulverformigt material
SE512433C2 (sv) 1998-07-30 2000-03-13 Microdrug Ag Förfarande för finfördelning och elektrostatisk uppladdning av ett pulver avsett för administrering främst genom inhalation jämte anordning för matning, finfördelning och elektrostatisk uppladdning av ett pulver avsett för administrering främst genom inhalation

Also Published As

Publication number Publication date
KR20030066606A (ko) 2003-08-09
SE0003082L (sv) 2002-01-29
PL360177A1 (en) 2004-09-06
RU2003101911A (ru) 2004-07-27
EP1315532A1 (en) 2003-06-04
WO2002018000A1 (en) 2002-03-07
CA2418039A1 (en) 2002-03-07
JP2004516046A (ja) 2004-06-03
CN1468121A (zh) 2004-01-14
AU2001280352A1 (en) 2002-03-13
SE516554C2 (sv) 2002-01-29
US6868853B1 (en) 2005-03-22
SE0003082D0 (sv) 2000-08-31

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired