BR0111014A - Compostos de praziquantel para o tratamento de doenças causadas por sarcocystis, neospora, toxoplasma e isospora - Google Patents
Compostos de praziquantel para o tratamento de doenças causadas por sarcocystis, neospora, toxoplasma e isosporaInfo
- Publication number
- BR0111014A BR0111014A BR0111014-4A BR0111014A BR0111014A BR 0111014 A BR0111014 A BR 0111014A BR 0111014 A BR0111014 A BR 0111014A BR 0111014 A BR0111014 A BR 0111014A
- Authority
- BR
- Brazil
- Prior art keywords
- praziquantel
- sarcocystis
- diseases caused
- treatment
- neospora
- Prior art date
Links
- FSVJFNAIGNNGKK-UHFFFAOYSA-N 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one Chemical class C1C(C2=CC=CC=C2CC2)N2C(=O)CN1C(=O)C1CCCCC1 FSVJFNAIGNNGKK-UHFFFAOYSA-N 0.000 title abstract 3
- 241000224003 Sarcocystis Species 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 241000567229 Isospora Species 0.000 title abstract 2
- 241001147660 Neospora Species 0.000 title abstract 2
- 241000223996 Toxoplasma Species 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229960002957 praziquantel Drugs 0.000 abstract 2
- 201000005485 Toxoplasmosis Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 244000045947 parasite Species 0.000 abstract 1
- -1 praziquantel compound Chemical class 0.000 abstract 1
- 238000011269 treatment regimen Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
"COMPOSTOS DE PRAZIQUANTEL PARA O TRATAMENTO DE DOENçAS CAUSADAS POR SARCOCYSTIS, NEOSPORA, TOXOPLASMA E ISOSPORA". São divulgadas neste caso composições e processos para tratar terapeuticamente, ou metafilaticamente, mamíferos infectados suscetíveis ou mamíferos infectados que sofrem de doenças neurológicas ou abortigênicas causadas por parasitas tais como Sarcocystis, Neosporose ou Toxoplasmose ou lsosporose que podem ser tratadas com um composto de praziquantel administrando a ele uma composição que contém uma quantidade farmaceuticamente eficaz de praziquantel ou derivado do mesmo, incluindo regimes de tratamento metafilático e de uma única dose alta.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/576,791 US6429211B1 (en) | 2000-05-23 | 2000-05-23 | Praziquantel compounds for treating diseases due to Sarcocystis Neospora Toxoplasma and Isospora |
PCT/US2001/016440 WO2001089497A2 (en) | 2000-05-23 | 2001-05-18 | Praziquantel compositions for treating diseases due to sarcocystis, neospora, toxoplasma and isospora |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0111014A true BR0111014A (pt) | 2003-04-08 |
Family
ID=24306001
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0111014-4A BR0111014A (pt) | 2000-05-23 | 2001-05-18 | Compostos de praziquantel para o tratamento de doenças causadas por sarcocystis, neospora, toxoplasma e isospora |
Country Status (19)
Country | Link |
---|---|
US (2) | US6429211B1 (pt) |
EP (1) | EP1296686B1 (pt) |
JP (1) | JP4991076B2 (pt) |
KR (1) | KR100821112B1 (pt) |
CN (1) | CN1250222C (pt) |
AT (1) | ATE310521T1 (pt) |
AU (1) | AU2001274886A1 (pt) |
BR (1) | BR0111014A (pt) |
CA (1) | CA2409926C (pt) |
DE (1) | DE60115237T2 (pt) |
DK (1) | DK1296686T3 (pt) |
ES (1) | ES2252242T3 (pt) |
HK (1) | HK1059894A1 (pt) |
HU (1) | HUP0302330A3 (pt) |
MX (1) | MXPA02011453A (pt) |
NZ (1) | NZ522687A (pt) |
PL (1) | PL202041B1 (pt) |
WO (1) | WO2001089497A2 (pt) |
ZA (1) | ZA200208770B (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006061214A1 (en) * | 2004-12-10 | 2006-06-15 | Bayer Healthcare Ag | Anthelmintic composition |
US8563554B2 (en) | 2009-03-17 | 2013-10-22 | Concert Pharmaceuticals, Inc. | Deuterated pyrazinoisoquinoline compounds |
US10137111B2 (en) | 2016-08-11 | 2018-11-27 | Adamis Pharmaceuticals Corporation | Drug compositions comprising an anti-parasitic and proton pump inhibitor |
US11564910B2 (en) | 2017-12-08 | 2023-01-31 | Adamis Pharmaceuticals Corporation | Drug compositions |
US20200138823A1 (en) * | 2018-11-02 | 2020-05-07 | Adamis Pharmaceuticals Corporation | Drug compositions |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2362539C2 (de) | 1973-12-17 | 1986-05-07 | Merck Patent Gmbh, 6100 Darmstadt | 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
US4447414A (en) | 1982-12-21 | 1984-05-08 | Cutter Laboratories, Inc. | Carnivore anthelmintics |
DE3634755A1 (de) * | 1986-10-11 | 1988-04-14 | Bayer Ag | Dermale behandlung von wurmerkrankungen der katze mit praziquantel |
DE3805660A1 (de) | 1988-02-24 | 1989-09-07 | Bayer Ag | Substituierte 1,2,4-triazindione, verfahren zu ihrer herstellung und ihre verwendung |
DE3826058A1 (de) | 1988-07-30 | 1990-02-08 | Bayer Ag | Mittel gegen fischparasiten |
US4933341A (en) | 1988-10-08 | 1990-06-12 | Bayer Aktiengesellschaft | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa |
US5196562A (en) | 1988-10-08 | 1993-03-23 | Bayer Aktiengesellschaft | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa |
EP0377903A3 (de) | 1989-01-09 | 1991-07-17 | Bayer Ag | Substituierte Hexahydro-1,2,4-triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung |
CN1044905A (zh) | 1989-02-16 | 1990-08-29 | 赫彻斯特股份公司 | 鱼和昆虫寄生虫对抗剂 |
DE4030042A1 (de) | 1990-05-17 | 1991-11-21 | Bayer Ag | Verwendung von substituierten 1,2,4-triazindionen |
DE4120138A1 (de) | 1991-06-19 | 1992-12-24 | Bayer Ag | Substituierte hexahydro-1,2,4-triazindione, verfahren zu ihrer herstellung, zwischenprodukte dafuer und ihre verwendung |
AUPM969994A0 (en) | 1994-11-28 | 1994-12-22 | Virbac S.A. | Equine anthelmintic formulations |
US5663155A (en) | 1994-11-30 | 1997-09-02 | The University Hospital | Compositions for the treatment of parasitic infections |
JPH0987196A (ja) * | 1995-09-25 | 1997-03-31 | Masatoshi Nakano | 寄生虫駆除・駆虫剤 |
US6051604A (en) * | 1995-12-07 | 2000-04-18 | The Proctor & Gamble Company | Methods and compositions for the prevention and treatment of gastrointestinal disorders |
US6180604B1 (en) * | 1996-08-21 | 2001-01-30 | Micrologix Biotech Inc. | Compositions and methods for treating infections using analogues of indolicidin |
AU5529600A (en) * | 1999-06-18 | 2001-01-09 | Bayer Aktiengesellschaft | Anthelmintic compositions |
-
2000
- 2000-05-23 US US09/576,791 patent/US6429211B1/en not_active Expired - Fee Related
-
2001
- 2001-05-18 ES ES01941541T patent/ES2252242T3/es not_active Expired - Lifetime
- 2001-05-18 AT AT01941541T patent/ATE310521T1/de active
- 2001-05-18 DK DK01941541T patent/DK1296686T3/da active
- 2001-05-18 HU HU0302330A patent/HUP0302330A3/hu unknown
- 2001-05-18 WO PCT/US2001/016440 patent/WO2001089497A2/en active IP Right Grant
- 2001-05-18 NZ NZ522687A patent/NZ522687A/en not_active IP Right Cessation
- 2001-05-18 PL PL360503A patent/PL202041B1/pl not_active IP Right Cessation
- 2001-05-18 CN CNB018100910A patent/CN1250222C/zh not_active Expired - Fee Related
- 2001-05-18 MX MXPA02011453A patent/MXPA02011453A/es active IP Right Grant
- 2001-05-18 CA CA002409926A patent/CA2409926C/en not_active Expired - Fee Related
- 2001-05-18 AU AU2001274886A patent/AU2001274886A1/en not_active Abandoned
- 2001-05-18 DE DE60115237T patent/DE60115237T2/de not_active Expired - Lifetime
- 2001-05-18 KR KR1020027014957A patent/KR100821112B1/ko not_active IP Right Cessation
- 2001-05-18 EP EP01941541A patent/EP1296686B1/en not_active Expired - Lifetime
- 2001-05-18 JP JP2001585742A patent/JP4991076B2/ja not_active Expired - Fee Related
- 2001-05-18 BR BR0111014-4A patent/BR0111014A/pt not_active Application Discontinuation
-
2002
- 2002-03-05 US US10/090,858 patent/US20020143018A1/en not_active Abandoned
- 2002-10-30 ZA ZA200208770A patent/ZA200208770B/en unknown
-
2004
- 2004-04-20 HK HK04102773A patent/HK1059894A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NZ522687A (en) | 2004-07-30 |
EP1296686B1 (en) | 2005-11-23 |
PL202041B1 (pl) | 2009-05-29 |
DE60115237T2 (de) | 2006-06-29 |
DK1296686T3 (da) | 2006-04-03 |
CN1452489A (zh) | 2003-10-29 |
PL360503A1 (en) | 2004-09-06 |
HK1059894A1 (en) | 2004-07-23 |
DE60115237D1 (de) | 2005-12-29 |
ES2252242T3 (es) | 2006-05-16 |
US20020143018A1 (en) | 2002-10-03 |
MXPA02011453A (es) | 2003-05-23 |
ATE310521T1 (de) | 2005-12-15 |
WO2001089497A3 (en) | 2002-11-28 |
HUP0302330A3 (en) | 2012-02-28 |
KR20020097257A (ko) | 2002-12-31 |
CA2409926A1 (en) | 2001-11-29 |
US6429211B1 (en) | 2002-08-06 |
AU2001274886A1 (en) | 2001-12-03 |
ZA200208770B (en) | 2003-10-30 |
CA2409926C (en) | 2009-11-03 |
JP4991076B2 (ja) | 2012-08-01 |
HUP0302330A2 (hu) | 2003-11-28 |
WO2001089497A2 (en) | 2001-11-29 |
JP2003534275A (ja) | 2003-11-18 |
EP1296686A2 (en) | 2003-04-02 |
CN1250222C (zh) | 2006-04-12 |
KR100821112B1 (ko) | 2008-04-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] |
Free format text: DE ACORDO COM O ART.34 "II" DA LPI (LEI 9279, DE 14/05/96), O EXAME FICA SUSPENSO PARA QUE O REQUERENTE APRESENTE DOCUMENTOS NECESSARIOS A REGULARIZACAO DO PROCESSO E EXAME DO PEDIDO. |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Free format text: PARA: INT. CL. A61K 31/47; A61P 33/10 Ipc: A61K 31/00 (2011.01), A61P 33/10 (2011.01) |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |