BR0110098A - Polinucleotìdeo, construção genética recombinante, vetor de expressão, célula hospedeira, animal transgênico, peptìdeo, métodos para triagem de um agente quanto à atividade farmacológica, de inibir a ligação do gnrh a seu receptor nativo in vivo, e de contracepção, e, usos do gnrh-r do tipo ii ou de um seu domìnio extracelular - Google Patents
Polinucleotìdeo, construção genética recombinante, vetor de expressão, célula hospedeira, animal transgênico, peptìdeo, métodos para triagem de um agente quanto à atividade farmacológica, de inibir a ligação do gnrh a seu receptor nativo in vivo, e de contracepção, e, usos do gnrh-r do tipo ii ou de um seu domìnio extracelularInfo
- Publication number
- BR0110098A BR0110098A BR0110098-0A BR0110098A BR0110098A BR 0110098 A BR0110098 A BR 0110098A BR 0110098 A BR0110098 A BR 0110098A BR 0110098 A BR0110098 A BR 0110098A
- Authority
- BR
- Brazil
- Prior art keywords
- gnrh
- type
- polynucleotide
- peptide
- screening
- Prior art date
Links
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 241001465754 Metazoa Species 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- 239000013604 expression vector Substances 0.000 title abstract 2
- 230000002068 genetic effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000000144 pharmacologic effect Effects 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 238000012216 screening Methods 0.000 title abstract 2
- 230000009261 transgenic effect Effects 0.000 title abstract 2
- 101150108262 gnrh1 gene Proteins 0.000 title 1
- 238000001727 in vivo Methods 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 102100033851 Gonadotropin-releasing hormone receptor Human genes 0.000 abstract 2
- 101710082444 Gonadotropin-releasing hormone receptor Proteins 0.000 abstract 2
- 102000008238 LHRH Receptors Human genes 0.000 abstract 1
- 108010021290 LHRH Receptors Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 241001515942 marmosets Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0009269A GB0009269D0 (en) | 2000-04-15 | 2000-04-15 | Receptor |
| GB0014761A GB0014761D0 (en) | 2000-06-17 | 2000-06-17 | Receptor |
| US21523200P | 2000-06-30 | 2000-06-30 | |
| PCT/GB2001/001755 WO2001078796A1 (fr) | 2000-04-15 | 2001-04-17 | Recepteur de la gonadoliberine de type ii et polynucleotides codant pour ce recepteur |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0110098A true BR0110098A (pt) | 2003-01-14 |
Family
ID=27255670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0110098-0A BR0110098A (pt) | 2000-04-15 | 2001-04-17 | Polinucleotìdeo, construção genética recombinante, vetor de expressão, célula hospedeira, animal transgênico, peptìdeo, métodos para triagem de um agente quanto à atividade farmacológica, de inibir a ligação do gnrh a seu receptor nativo in vivo, e de contracepção, e, usos do gnrh-r do tipo ii ou de um seu domìnio extracelular |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1337282A2 (fr) |
| JP (1) | JP2003530837A (fr) |
| KR (1) | KR20020097218A (fr) |
| AU (1) | AU2001248599A1 (fr) |
| BR (1) | BR0110098A (fr) |
| CA (1) | CA2404127A1 (fr) |
| HU (1) | HUP0301666A2 (fr) |
| IL (1) | IL152011A0 (fr) |
| NO (1) | NO20024937L (fr) |
| PL (1) | PL357684A1 (fr) |
| WO (1) | WO2001078796A1 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002000701A2 (fr) * | 2000-06-26 | 2002-01-03 | Bayer Aktiengesellschaft | Regulation du recepteur humain couple a la proteine g semblable au recepteur de l'hormone liberant la gonadotropine |
| WO2002070701A2 (fr) * | 2001-03-01 | 2002-09-12 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Nouveau recepteur gnrh humain |
| US20050282745A1 (en) * | 2001-08-28 | 2005-12-22 | Siler-Khodr Theresa M | Non-mammalian GnRH analogs and uses thereof in regulation of fertility and pregnancy |
| WO2004009636A2 (fr) * | 2002-07-22 | 2004-01-29 | Ardana Bioscience Limited | Modulateur de la gnrh |
| DK1512016T3 (da) | 2002-07-22 | 2006-07-03 | Ardana Bioscience Ltd | Screeningsmetode og antitumor-medikamentkandidat opnået derved |
| AU2003248955A1 (en) * | 2002-07-22 | 2004-02-09 | Ardana Bioscience Limited | Screening method |
| KR101038183B1 (ko) * | 2010-12-27 | 2011-06-01 | 강범준 | 조립식 파형블록과 이를 이용한 호안 경사면 피복방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994000590A1 (fr) * | 1992-06-23 | 1994-01-06 | The Mt. Sinai School Of Medicine Of The City University Of New York | CLONAGE ET EXPRESSION D'UN RECEPTEUR D'HORMONE LIBERANT DE LA GONADOTROPINE (R-HLGn) |
| WO1997047743A1 (fr) * | 1996-06-13 | 1997-12-18 | Zymogenetics, Inc. | Recepteur humain de l'hormone de liberation de la gonadotrophine de type ii |
-
2001
- 2001-04-17 AU AU2001248599A patent/AU2001248599A1/en not_active Abandoned
- 2001-04-17 KR KR1020027013776A patent/KR20020097218A/ko not_active Application Discontinuation
- 2001-04-17 PL PL01357684A patent/PL357684A1/xx unknown
- 2001-04-17 CA CA002404127A patent/CA2404127A1/fr not_active Abandoned
- 2001-04-17 IL IL15201101A patent/IL152011A0/xx unknown
- 2001-04-17 HU HU0301666A patent/HUP0301666A2/hu unknown
- 2001-04-17 JP JP2001576095A patent/JP2003530837A/ja active Pending
- 2001-04-17 EP EP01921629A patent/EP1337282A2/fr not_active Withdrawn
- 2001-04-17 BR BR0110098-0A patent/BR0110098A/pt not_active Application Discontinuation
- 2001-04-17 WO PCT/GB2001/001755 patent/WO2001078796A1/fr not_active Application Discontinuation
-
2002
- 2002-10-14 NO NO20024937A patent/NO20024937L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2404127A1 (fr) | 2001-10-25 |
| HUP0301666A2 (hu) | 2003-08-28 |
| WO2001078796A9 (fr) | 2002-02-28 |
| NO20024937L (no) | 2002-12-09 |
| PL357684A1 (en) | 2004-07-26 |
| EP1337282A2 (fr) | 2003-08-27 |
| WO2001078796A3 (fr) | 2003-04-24 |
| NO20024937D0 (no) | 2002-10-14 |
| IL152011A0 (en) | 2003-04-10 |
| WO2001078796A1 (fr) | 2001-10-25 |
| JP2003530837A (ja) | 2003-10-21 |
| KR20020097218A (ko) | 2002-12-31 |
| AU2001248599A1 (en) | 2001-10-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0113921A (pt) | ácidos nucléicos e polipeptìdeos receptores | |
| AR006188A1 (es) | "composicion farmaceutica para inhibir la actividad de serinproteasa, metodo in vitro para inhibir la actividad de serinproteasa y metodo para preparar dicha composicion". | |
| Fischer-Colbrie et al. | Sequence analysis, tissue distribution and regulation by cell depolarization, and second messengers of bovine secretogranin II (chromogranin C) mRNA. | |
| PH12013502425A1 (en) | Smoothened polypeptides and methods of use | |
| WO2004069876A3 (fr) | Reponse de lymphocyte t durable | |
| DE60140218D1 (de) | Expressionsvektor für tierische zellen | |
| DE69939327D1 (de) | Funktionelle antagonisten von hedgehog-aktivität | |
| Albert et al. | Direct synthesis of [DOTA-DPhe1]-octreotide and [DOTA-DPhe1, Tyr3]-octreotide (SMT487): two conjugates for systemic delivery of radiotherapeutical nuclides to somatostatin receptor positive tumors in man | |
| BR0110098A (pt) | Polinucleotìdeo, construção genética recombinante, vetor de expressão, célula hospedeira, animal transgênico, peptìdeo, métodos para triagem de um agente quanto à atividade farmacológica, de inibir a ligação do gnrh a seu receptor nativo in vivo, e de contracepção, e, usos do gnrh-r do tipo ii ou de um seu domìnio extracelular | |
| ATE293169T1 (de) | Latency associated peptide von tgf-beta um pharmazeutisch aktive proteine latent zu machen | |
| KR960704932A (ko) | 당단백질 호르몬 4개조의 단일-사슬 형태(single-chain forms of the glycoprotein hormone quartet) | |
| Yotov et al. | Nucleotide sequence of a mouse cDNA encoding the nonhistone chromosomal high mobility group protein-1 (HMG1). | |
| Eberle | Proopiomelanocortin and the melanocortin peptides | |
| WO2002050111A3 (fr) | Laminine 10 isolee | |
| BR9812138A (pt) | Métodos e composições para terapias empregando genes codificando proteìnas segregadas tal como interferon-beta | |
| ATE357526T1 (de) | Modifizierte hcv peptid-impfstoffe | |
| ATE364392T1 (de) | Zusammensetzung aus liganden/lytischen petiden und ihre verwendung | |
| ATE294816T1 (de) | Neue, physiologisch aktive peptide und ihre verwendung. | |
| WO2002070657A3 (fr) | 93870, recepteur couple a la proteine g humaine et ses utilisations | |
| PT1095143E (pt) | Inibidor para o diagnóstico e tratamento de doentes com hemofilia a | |
| Anderson | Stress proteins and apoptosis in prenatal development, cancer and medicine | |
| DE60142356D1 (de) | 18480 humane proteinkinasemoleküle und ihre verwendungen | |
| WO2002013845A3 (fr) | Inflammation associee au recepteur couple a la proteine g | |
| IL138585A (en) | Vertebrate patched -2 protein | |
| Elkon | Ribosomal RNP |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |