BR0108659A - Métodos para tratamento ou prevenção ou profilaxia de câncer de mama, para detecção, diagnóstico e/ou avaliação ou prognóstico quanto ao câncer de mama, para monitoração e/ou estimativa de tratamento do câncer de mama, para identificação da presença ou ausência de células de câncer de mama metastáticas em um amostra biológica e para avaliação ou identificação de compostos, usos de uma ou mais bcmps, de uma composição, de um anticorpo, de ácido nucleico e de um agente que interaja com ou module a atividade de uma ou mais bcmps, vacina, composição, kit e anticorpo - Google Patents
Métodos para tratamento ou prevenção ou profilaxia de câncer de mama, para detecção, diagnóstico e/ou avaliação ou prognóstico quanto ao câncer de mama, para monitoração e/ou estimativa de tratamento do câncer de mama, para identificação da presença ou ausência de células de câncer de mama metastáticas em um amostra biológica e para avaliação ou identificação de compostos, usos de uma ou mais bcmps, de uma composição, de um anticorpo, de ácido nucleico e de um agente que interaja com ou module a atividade de uma ou mais bcmps, vacina, composição, kit e anticorpoInfo
- Publication number
- BR0108659A BR0108659A BR0108659-6A BR0108659A BR0108659A BR 0108659 A BR0108659 A BR 0108659A BR 0108659 A BR0108659 A BR 0108659A BR 0108659 A BR0108659 A BR 0108659A
- Authority
- BR
- Brazil
- Prior art keywords
- breast cancer
- bcmps
- antibody
- composition
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A61K51/1051—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57525—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57555—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57557—Immunoassay; Biospecific binding assay; Materials therefor for cancer of other specific parts of the body, e.g. brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Optics & Photonics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0004576.5A GB0004576D0 (en) | 2000-02-25 | 2000-02-25 | Proteins |
| GB0031341A GB0031341D0 (en) | 2000-12-21 | 2000-12-21 | Protein |
| PCT/GB2001/000748 WO2001062784A2 (en) | 2000-02-25 | 2001-02-21 | Use of breast cancer associated membrane proteins (bcmp) for treatment, prophylaxis and diagnosis of breast cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0108659A true BR0108659A (pt) | 2002-11-05 |
Family
ID=26243736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0108659-6A BR0108659A (pt) | 2000-02-25 | 2001-02-21 | Métodos para tratamento ou prevenção ou profilaxia de câncer de mama, para detecção, diagnóstico e/ou avaliação ou prognóstico quanto ao câncer de mama, para monitoração e/ou estimativa de tratamento do câncer de mama, para identificação da presença ou ausência de células de câncer de mama metastáticas em um amostra biológica e para avaliação ou identificação de compostos, usos de uma ou mais bcmps, de uma composição, de um anticorpo, de ácido nucleico e de um agente que interaja com ou module a atividade de uma ou mais bcmps, vacina, composição, kit e anticorpo |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20030130214A1 (https=) |
| EP (2) | EP1259604A1 (https=) |
| JP (1) | JP2003524017A (https=) |
| KR (1) | KR100740761B1 (https=) |
| CN (1) | CN100384875C (https=) |
| AT (1) | ATE352311T1 (https=) |
| AU (3) | AU2001233929C1 (https=) |
| BR (1) | BR0108659A (https=) |
| CA (1) | CA2399999A1 (https=) |
| DE (1) | DE60126248T2 (https=) |
| ES (1) | ES2279801T3 (https=) |
| IL (1) | IL151448A0 (https=) |
| NZ (1) | NZ520967A (https=) |
| WO (2) | WO2001062784A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7054758B2 (en) | 2001-01-30 | 2006-05-30 | Sciona Limited | Computer-assisted means for assessing lifestyle risk factors |
| GB0125072D0 (en) * | 2001-10-18 | 2001-12-12 | Oxford Glycosciences Uk Ltd | Protein |
| WO2003075014A2 (en) * | 2002-03-06 | 2003-09-12 | Oxford Glycosciences (Uk) Ltd | Protein-protein interactions in human tumours involving bcmp-7 and bcmp-11 |
| WO2003087834A2 (en) * | 2002-04-08 | 2003-10-23 | Affinium Pharmaceuticals, Inc. | High throughput analysis of recombinant proteins in multi-well plates |
| GB0208331D0 (en) * | 2002-04-11 | 2002-05-22 | Oxford Glycosciences Uk Ltd | Proteins |
| FR2846426B1 (fr) * | 2002-10-28 | 2004-12-10 | Bio Merieux | Procede de dosage du ngf pour le diagnostic in vitro du cancer du sein et utilisation en therapie |
| US7408028B2 (en) * | 2002-12-06 | 2008-08-05 | Sinapore General Hospital Pte Ltd. | Peptides, antibodies thereto, and their use in treatment of central nervous system, damage |
| WO2005029083A1 (en) * | 2003-09-22 | 2005-03-31 | Green Peptide Co., Ltd. | Prognosis in cancer patients vaccinated with a cancer antigen peptide-associated agent |
| US8603481B2 (en) | 2003-10-10 | 2013-12-10 | Chugai Seiyaku Kabushiki Kaisha | Therapeutic agents for solid tumors |
| JP2007520217A (ja) * | 2004-01-27 | 2007-07-26 | コンピュゲン ユーエスエイ,インク. | 新規ヌクレオチドおよびアミノ酸配列、ならびにそれを用いた乳癌診断のためのアッセイおよび使用方法 |
| KR100763902B1 (ko) * | 2004-02-20 | 2007-10-05 | 삼성전자주식회사 | 유방암 특이적 단백질, 그를 코딩하는 유전자, 및 상기단백질 또는 유전자를 이용한 유방암의 진단 방법 |
| WO2008104803A2 (en) * | 2007-02-26 | 2008-09-04 | Oxford Genome Sciences (Uk) Limited | Proteins |
| KR101398079B1 (ko) * | 2011-10-10 | 2014-05-27 | 재단법인 의약바이오컨버젼스연구단 | 글리실-티알엔에이 합성효소 및 캐드헤린을 이용한 암 예방 또는 치료제의 스크리닝 방법 |
| CN104447975A (zh) * | 2014-11-18 | 2015-03-25 | 深圳市人口和计划生育科学研究所 | 一种提取人肿瘤细胞膜蛋白的方法 |
| US20180200331A1 (en) * | 2015-07-10 | 2018-07-19 | University Of Iowa Research Foundation | Bst-2 as a therapeutic target and diagnostic marker for breast cancer growth and metastasis |
| WO2018119142A1 (en) | 2016-12-21 | 2018-06-28 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| KR102312897B1 (ko) * | 2021-02-26 | 2021-10-15 | 에스케이바이오사이언스(주) | 목적 단백질의 고수율 정제방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0929575A4 (en) * | 1996-08-23 | 2004-09-08 | Human Genome Sciences Inc | NEW HUMAN GROWTH FACTORS. |
| DE19813839A1 (de) * | 1998-03-20 | 1999-09-23 | Metagen Gesellschaft Fuer Genomforschung Mbh | Menschliche Nukleinsäuresequenzen aus Brusttumorgewebe |
| JP2004500029A (ja) * | 1999-06-30 | 2004-01-08 | コリクサ コーポレイション | 肺癌の治療および診断のための組成物および方法 |
-
2001
- 2001-02-21 NZ NZ520967A patent/NZ520967A/en unknown
- 2001-02-21 BR BR0108659-6A patent/BR0108659A/pt not_active IP Right Cessation
- 2001-02-21 WO PCT/GB2001/000748 patent/WO2001062784A2/en not_active Ceased
- 2001-02-21 IL IL15144801A patent/IL151448A0/xx unknown
- 2001-02-21 AU AU2001233929A patent/AU2001233929C1/en not_active Ceased
- 2001-02-21 EP EP01905949A patent/EP1259604A1/en not_active Withdrawn
- 2001-02-21 ES ES01905965T patent/ES2279801T3/es not_active Expired - Lifetime
- 2001-02-21 AU AU2001233913A patent/AU2001233913A1/en not_active Abandoned
- 2001-02-21 WO PCT/GB2001/000729 patent/WO2001062914A1/en not_active Ceased
- 2001-02-21 EP EP01905965A patent/EP1257285B1/en not_active Expired - Lifetime
- 2001-02-21 JP JP2001562565A patent/JP2003524017A/ja active Pending
- 2001-02-21 KR KR1020027011130A patent/KR100740761B1/ko not_active Expired - Fee Related
- 2001-02-21 AU AU3392901A patent/AU3392901A/xx active Pending
- 2001-02-21 DE DE60126248T patent/DE60126248T2/de not_active Expired - Fee Related
- 2001-02-21 CA CA002399999A patent/CA2399999A1/en not_active Abandoned
- 2001-02-21 CN CNB018084885A patent/CN100384875C/zh not_active Expired - Fee Related
- 2001-02-21 AT AT01905965T patent/ATE352311T1/de not_active IP Right Cessation
- 2001-02-23 US US09/791,392 patent/US20030130214A1/en not_active Abandoned
-
2002
- 2002-08-23 US US10/227,616 patent/US20030099662A1/en not_active Abandoned
-
2006
- 2006-08-24 US US11/509,841 patent/US20070212368A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1259604A1 (en) | 2002-11-27 |
| KR20030007440A (ko) | 2003-01-23 |
| US20030130214A1 (en) | 2003-07-10 |
| EP1257285B1 (en) | 2007-01-24 |
| DE60126248T2 (de) | 2007-07-05 |
| AU3392901A (en) | 2001-09-03 |
| CA2399999A1 (en) | 2001-08-30 |
| AU2001233929C1 (en) | 2006-03-02 |
| EP1257285A2 (en) | 2002-11-20 |
| WO2001062914A1 (en) | 2001-08-30 |
| WO2001062784A2 (en) | 2001-08-30 |
| KR100740761B1 (ko) | 2007-07-19 |
| HK1056692A1 (zh) | 2004-02-27 |
| US20030099662A1 (en) | 2003-05-29 |
| DE60126248D1 (de) | 2007-03-15 |
| WO2001062784A3 (en) | 2002-01-31 |
| IL151448A0 (en) | 2003-04-10 |
| JP2003524017A (ja) | 2003-08-12 |
| NZ520967A (en) | 2004-04-30 |
| AU2001233929B2 (en) | 2005-09-08 |
| ES2279801T3 (es) | 2007-09-01 |
| US20070212368A1 (en) | 2007-09-13 |
| CN100384875C (zh) | 2008-04-30 |
| ATE352311T1 (de) | 2007-02-15 |
| AU2001233913A1 (en) | 2001-09-03 |
| CN1426307A (zh) | 2003-06-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0108659A (pt) | Métodos para tratamento ou prevenção ou profilaxia de câncer de mama, para detecção, diagnóstico e/ou avaliação ou prognóstico quanto ao câncer de mama, para monitoração e/ou estimativa de tratamento do câncer de mama, para identificação da presença ou ausência de células de câncer de mama metastáticas em um amostra biológica e para avaliação ou identificação de compostos, usos de uma ou mais bcmps, de uma composição, de um anticorpo, de ácido nucleico e de um agente que interaja com ou module a atividade de uma ou mais bcmps, vacina, composição, kit e anticorpo | |
| Seerangaiyan et al. | The tongue microbiome in healthy subjects and patients with intra-oral halitosis | |
| BR0115715A (pt) | Análise de expressão de ácidos nucleìcos e polipeptìdeos úteis na diagnose e tratamento de câncer da próstata | |
| BR9814821A (pt) | Ensaio de analìtico usando marcas em partìculas | |
| Hernandez et al. | A five-year report on experience in the detection of pheochromocytoma | |
| EP1474510A4 (en) | COMPOSITIONS AND METHODS FOR DETECTION, DIAGNOSIS AND THERAPY OF HEMATOLOGICAL MALIGNITIES | |
| Meisel et al. | The performance of BRCA1 immunohistochemistry for detecting germline, somatic, and epigenetic BRCA1 loss in high-grade serous ovarian cancer | |
| Siemund et al. | Establishing aluminium contact allergy | |
| BRPI0602594A (pt) | dispositivo e método para determinação rápida da eficácia de processos de esterilização ou desinfecção | |
| BR0210579A (pt) | Anticorpos, cadeias pesadas e leves, composição farmacêutica e métodos de detecção do nìvel de opgl em amostra biológia e de tratamento | |
| Seidel et al. | Modified nucleosides as biomarkers for early cancer diagnose in exposed populations | |
| BRPI0506752A (pt) | sistema ou método para avaliar a circulação de sangue periférica de um indivìduo | |
| Rana | Crime investigation through DNA methylation analysis: methods and applications in forensics | |
| Crunelle et al. | Hair ethyl glucuronide as a biomarker of alcohol consumption in alcohol-dependent patients: role of gender differences | |
| TR199902828T2 (xx) | Lizofosfolipidlerin de�i�mi� konsantrasyonlar� ile birle�tirilmi� kanser belirleme y�ntemi. | |
| Ponten et al. | Patch testing with 2.0%(0.60 mg/cm2) formaldehyde instead of 1.0%(0.30 mg/cm2) detects significantly more contact allergy | |
| CA3047060A1 (en) | Methods of determining colorectal cancer status in an individual | |
| BRPI0612169A2 (pt) | métodos prognósticos, métodos de detecção, de distinção, de identificação, de determinação e de monitoramento relacionados com cáncer de pulmão, métodos para amplificação de um ácido nucléico que codifica c-met humano , biomarcadores de cáncer de pulmão, agentes de imagem de cáncer de pulmão, polinucleotìdeos, agente s de ligação de antìgeno, conjuntos, meios legìveis em computador e kits e/ou artigos de fabricação | |
| BRPI0809958C1 (pt) | conjunto de esferas para a detecção de uma cepa de hpv e/ou para diferenciação entre duas ou mais cepas de hpv, método para a preparação do referido conjunto de esferas, método para o diagnóstico de infecção por hpv, método para determinação do risco de um indivíduo humano desenvolver uma doença associada a uma ou mais cepas de hpv e par de iniciadores para amplificação de oligonucleotídeo direcionado ao hpv oncogênico | |
| Isaksson et al. | Multicentre patch testing with fragrance mix II and hydroxyisohexyl 3-cyclohexene carboxaldehyde by the Swedish Contact Dermatitis Research Group. | |
| ATE553112T1 (de) | Ttk in der diagnose und als therapeutisches target bei krebs | |
| Engarås | Individual cutoff levels of carcinoembryonic antigen and CA 242 indicate recurrence of colorectal cancer with high sensitivity | |
| Richards-Rios et al. | Changes in the faecal microbiome of pied tamarins (Saguinus bicolor) associated with chronic, recurrent diarrhoea and weight loss | |
| BR9910372A (pt) | Processos para detectar tecido canceroso, e, para realizar um procedimento cirúrgico para remover uma lesão cancerosa de um tecido | |
| Hegde et al. | Relating tooth‐and blood‐lead levels in children residing near a zinc–lead smelter in India |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 11A ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012. |