BR0108436A - Método para a produção de corpos embrióides a partir de células tronco embrióticas de primatas - Google Patents
Método para a produção de corpos embrióides a partir de células tronco embrióticas de primatasInfo
- Publication number
- BR0108436A BR0108436A BR0108436-4A BRPI0108436A BR0108436A BR 0108436 A BR0108436 A BR 0108436A BR PI0108436 A BRPI0108436 A BR PI0108436A BR 0108436 A BR0108436 A BR 0108436A
- Authority
- BR
- Brazil
- Prior art keywords
- embryoid bodies
- production
- cells
- primate
- stem cells
- Prior art date
Links
- 241000288906 Primates Species 0.000 title abstract 4
- 210000002242 embryoid body Anatomy 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 210000000130 stem cell Anatomy 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 5
- 230000001464 adherent effect Effects 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 210000001671 embryonic stem cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"MéTODO PARA A PRODUçãO DE CORPOS EMBRIóIDES A PARTIR DE CéLULAS TRONCO EMBRIÈNICAS DE PRIMATAS". Corpos embriónicos primatas são formados a partir de células ES primatas. As células ES formam agrupamentos. Em seguida se remove os agrupamentos como grupos, e permite a incubação sob condições não-aderentes. O desenvolvimento dos corpos embrióides a partir de células ES primatas é dependente da manutenção da agregação das células, na medida em que as células individualizadas irão rapidamente morrer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/510,444 | 2000-02-21 | ||
US09/510,444 US6602711B1 (en) | 2000-02-21 | 2000-02-21 | Method of making embryoid bodies from primate embryonic stem cells |
PCT/US2001/005252 WO2001062899A2 (en) | 2000-02-21 | 2001-02-20 | Method of making embryoid bodies from primate embryonic stem cells |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0108436A true BR0108436A (pt) | 2003-03-25 |
BRPI0108436B1 BRPI0108436B1 (pt) | 2021-02-23 |
BRPI0108436B8 BRPI0108436B8 (pt) | 2021-05-25 |
Family
ID=24030756
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0108436-4 BRPI0108436B8 (pt) | 2000-02-21 | 2001-02-20 | método para produzir corpos embrionários primatas a partir de colônias de células-tronco embrionárias primatas que são aderentes a um substrato |
Country Status (15)
Country | Link |
---|---|
US (2) | US6602711B1 (pt) |
EP (1) | EP1257634A2 (pt) |
JP (1) | JP5339661B2 (pt) |
KR (1) | KR100812856B1 (pt) |
CN (1) | CN1404526A (pt) |
AU (3) | AU3849101A (pt) |
BR (1) | BRPI0108436B8 (pt) |
CA (1) | CA2400158C (pt) |
HK (1) | HK1052951A1 (pt) |
IL (2) | IL151176A0 (pt) |
IS (1) | IS6514A (pt) |
MX (1) | MXPA02008054A (pt) |
NO (1) | NO20023949L (pt) |
NZ (1) | NZ520700A (pt) |
WO (1) | WO2001062899A2 (pt) |
Families Citing this family (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
IL129966A (en) * | 1999-05-14 | 2009-12-24 | Technion Res & Dev Foundation | ISOLATED HUMAN EMBRYOID BODIES (hEB) DERIVED FROM HUMAN EMBRYONIC STEM CELLS |
US10638734B2 (en) | 2004-01-05 | 2020-05-05 | Abt Holding Company | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
US8252280B1 (en) | 1999-08-05 | 2012-08-28 | Regents Of The University Of Minnesota | MAPC generation of muscle |
US7015037B1 (en) | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
US20050042749A1 (en) * | 2001-05-16 | 2005-02-24 | Carpenter Melissa K. | Dopaminergic neurons and proliferation-competent precursor cells for treating Parkinson's disease |
US6602711B1 (en) * | 2000-02-21 | 2003-08-05 | Wisconsin Alumni Research Foundation | Method of making embryoid bodies from primate embryonic stem cells |
US7250294B2 (en) * | 2000-05-17 | 2007-07-31 | Geron Corporation | Screening small molecule drugs using neural cells differentiated from human embryonic stem cells |
US20020009743A1 (en) * | 2000-05-17 | 2002-01-24 | Carpenter Melissa K. | Neural progenitor cell populations |
EP1315835A2 (en) | 2000-08-01 | 2003-06-04 | Yissum Research Development Company of the Hebrew University of Jerusalem | Directed differentiation of embryonic cells |
CA2435826A1 (en) * | 2001-01-24 | 2002-08-01 | The Government Of The United States Of America | Differentiation of stem cells to pancreatic endocrine cells |
EP1491093B1 (en) | 2001-02-14 | 2013-07-31 | ABT Holding Company | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
US20030211605A1 (en) * | 2001-05-01 | 2003-11-13 | Lee Sang-Hun | Derivation of midbrain dopaminergic neurons from embryonic stem cells |
WO2003008535A2 (en) * | 2001-07-20 | 2003-01-30 | Technion Research And Development Foundation Ltd. | Methods of generating human cardiac cells and tissues and uses thereof |
JP4317337B2 (ja) * | 2001-10-16 | 2009-08-19 | 株式会社リプロセル | 細胞株継代用酵素溶液、および、それを用いた霊長類胚性幹細胞の培養増殖方法 |
US6759244B2 (en) | 2001-11-08 | 2004-07-06 | Art Institute Of New York And New Jersey, Inc. | Composite blastocysts (CBs) from aggregates of dissociated cells of non-viable pre-embryos |
US7799324B2 (en) | 2001-12-07 | 2010-09-21 | Geron Corporation | Using undifferentiated embryonic stem cells to control the immune system |
US20050170506A1 (en) * | 2002-01-16 | 2005-08-04 | Primegen Biotech Llc | Therapeutic reprogramming, hybrid stem cells and maturation |
US20030134422A1 (en) * | 2002-01-16 | 2003-07-17 | Sayre Chauncey Bigelow | Stem cell maturation for all tissue lines |
US20050090004A1 (en) * | 2003-01-16 | 2005-04-28 | Sayre Chauncey B. | Stem cell maturation for all tissue lines |
US20030162290A1 (en) * | 2002-01-25 | 2003-08-28 | Kazutomo Inoue | Method for inducing differentiation of embryonic stem cells into functioning cells |
US7160719B2 (en) * | 2002-06-07 | 2007-01-09 | Mayo Foundation For Medical Education And Research | Bioartificial liver system |
AU2003269379A1 (en) * | 2002-10-31 | 2004-05-25 | Pfizer Products Inc. | Suspension method for producing embryoid bodies, and compositions and methods related thereto |
US7947499B2 (en) * | 2002-11-29 | 2011-05-24 | Technion Research & Development Foundation Ltd. | Method of dynamically culturing embryonic stem cells |
CA2518577A1 (en) * | 2003-03-12 | 2004-09-23 | Reliance Life Sciences Pvt. Ltd. | Derivation of terminally differentiated dopaminergic neurons from human embryonic stem cells |
US9567591B2 (en) | 2003-05-15 | 2017-02-14 | Mello Biotechnology, Inc. | Generation of human embryonic stem-like cells using intronic RNA |
US20090203141A1 (en) * | 2003-05-15 | 2009-08-13 | Shi-Lung Lin | Generation of tumor-free embryonic stem-like pluripotent cells using inducible recombinant RNA agents |
CN1788079A (zh) * | 2003-06-13 | 2006-06-14 | 湖南惠霖生命科技有限公司 | 一种分离和培养人类多能胚胎干细胞的方法 |
AU2004256209B2 (en) * | 2003-07-08 | 2010-04-08 | Axiogenesis Ag | Novel method for the preparation of embryoid bodies (EBs) and uses thereof |
US7820439B2 (en) * | 2003-09-03 | 2010-10-26 | Reliance Life Sciences Pvt Ltd. | In vitro generation of GABAergic neurons from pluripotent stem cells |
US20070141703A1 (en) * | 2003-11-19 | 2007-06-21 | Stanley Edouard G | Methods for producing blood products from pluripotent cells in cell culture |
WO2005056755A2 (en) * | 2003-12-02 | 2005-06-23 | Catholic Healthcare West | Compositions and methods for propagation of neural progenitor cells |
US20070269412A1 (en) | 2003-12-02 | 2007-11-22 | Celavie Biosciences, Llc | Pluripotent cells |
US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
SG10201606441SA (en) * | 2004-01-23 | 2016-09-29 | Astellas Inst For Regenerative Medicine | Improved modalities for the treatment of degenerative diseases of the retina |
EP1730268A2 (en) * | 2004-04-01 | 2006-12-13 | Wisconsin Alumni Research Foundation | Differentiation of stem cells to endoderm and pancreatic lineage |
EP1740945B1 (en) | 2004-04-07 | 2018-09-19 | Ncardia AG | Non-invasive, in vitro functional tissue assay systems |
CA2565858C (en) | 2004-05-11 | 2021-06-22 | Axiogenesis Ag | Assay for drug discovery based on in vitro differentiated cells |
US20050277124A1 (en) | 2004-06-10 | 2005-12-15 | White Steven M | Cardiac conduction system cells and uses thereof |
WO2005123902A1 (ja) * | 2004-06-18 | 2005-12-29 | Riken | 無血清浮遊培養による胚性幹細胞の神経分化誘導法 |
US20070148767A1 (en) * | 2005-12-28 | 2007-06-28 | Mei-Ju Yang | Method of forming multicellular spheroids from the cultured cells |
KR100785049B1 (ko) | 2006-01-11 | 2007-12-12 | 한국과학기술연구원 | 줄기세포로부터 배아체를 형성 및 성장시키는 방법 및 장치 |
US20070238169A1 (en) * | 2006-04-11 | 2007-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Cell sorter and culture system |
WO2007120811A2 (en) | 2006-04-14 | 2007-10-25 | Advanced Cell Technology, Inc. | Hemangio-colony forming cells |
WO2007149926A1 (en) * | 2006-06-20 | 2007-12-27 | Wisconsin Alumni Research Foundation | Method for culturing stem cells |
AU2007321928A1 (en) | 2006-11-24 | 2008-05-29 | Regents Of The University Of Minnesota | Endodermal progenitor cells |
EP2607477B1 (en) | 2007-05-03 | 2020-09-23 | The Brigham and Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
US20110236971A2 (en) | 2007-09-25 | 2011-09-29 | Maksym Vodyanyk | Generation of Clonal Mesenchymal Progenitors and Mesenchymal Stem Cell Lines Under Serum-Free Conditions |
KR101849336B1 (ko) | 2007-10-12 | 2018-04-16 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | Rpe 세포의 개선된 생산 방법 및 rpe 세포의 조성물 |
EP3118308B1 (en) | 2008-04-30 | 2021-03-03 | SanBio, Inc. | Neural regenerating cells with alterations in dna methylation |
ES2685969T3 (es) * | 2008-05-06 | 2018-10-15 | Astellas Institute For Regenerative Medicine | Células formadoras de colonias hemangioblásticas y células hemangioblásticas no injertables |
KR101803562B1 (ko) | 2008-05-06 | 2017-12-01 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 다능성 줄기세포로부터 유도된 탈핵 적혈구계 세포를 생산하는 방법 |
US9394538B2 (en) | 2008-05-07 | 2016-07-19 | Shi-Lung Lin | Development of universal cancer drugs and vaccines |
US8956867B2 (en) | 2008-11-07 | 2015-02-17 | Wisconsin Alumni Research Foundation | Method for culturing stem cells |
US20110243898A1 (en) * | 2008-12-10 | 2011-10-06 | The University Of Louisville Research Foundation, Inc. | Somatic cell-derived pluripotent cells and methods of use therefor |
US20100209399A1 (en) * | 2009-02-13 | 2010-08-19 | Celavie Biosciences, Llc | Brain-derived stem cells for repair of musculoskeletal system in vertebrate subjects |
EP2772533B1 (en) * | 2009-03-09 | 2017-02-01 | Toyo Seikan Group Holdings, Ltd. | Cell culture method, cell culture device, method for counting subject matters to be counted in container and device for counting |
CN102421467B (zh) | 2009-03-13 | 2015-04-22 | 梅约医学教育与研究基金会 | 生物人工肝 |
WO2011017315A2 (en) * | 2009-08-03 | 2011-02-10 | Recombinetics, Inc. | Methods and compositions for targeted gene modification |
US8415155B2 (en) | 2009-10-19 | 2013-04-09 | Cellular Dynamics International, Inc. | Cardiomyocyte production |
IL281453B (en) | 2009-11-17 | 2022-07-01 | Astellas Inst For Regenerative Medicine | Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells |
EP2526189B1 (en) | 2010-01-22 | 2016-10-12 | Kyoto University | Method for improving induced pluripotent stem cell generation efficiency |
US8558913B2 (en) * | 2010-02-08 | 2013-10-15 | Apple Inc. | Capture condition selection from brightness and motion |
WO2011116361A1 (en) * | 2010-03-19 | 2011-09-22 | Amerstem, Inc. | Compositions and manufacture of mammalian stem cell-based cosmetics |
EP2582792B1 (en) | 2010-06-18 | 2018-10-31 | FUJIFILM Cellular Dynamics, Inc. | Cardiomyocyte medium with dialyzed serum |
US9181529B2 (en) | 2010-10-19 | 2015-11-10 | Cellular Dynamics International, Inc. | Titration of differentiation medium components |
AU2011316830A1 (en) | 2010-10-22 | 2013-05-02 | Biotime Inc. | Methods of modifying transcriptional regulatory networks in stem cells |
EP2647699B1 (en) | 2010-12-03 | 2020-04-01 | Kyoto University | Efficient method for establishing induced pluripotent stem cells |
US9700596B2 (en) | 2011-03-04 | 2017-07-11 | The Regents Of The University Of California | Locally released growth factors to mediate motor recovery after stroke |
CA2831609C (en) | 2011-03-30 | 2019-06-11 | Cellular Dynamics International, Inc. | Priming of pluripotent stem cells for neural differentiation |
EP2694080B1 (en) | 2011-04-06 | 2018-03-14 | SanBio, Inc. | Methods and compositions for modulating peripheral immune function |
WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
CN102329770A (zh) * | 2011-09-23 | 2012-01-25 | 安徽农业大学 | 改进的小鼠拟胚体制作方法 |
AU2013237760A1 (en) | 2012-10-08 | 2014-04-24 | Biotime, Inc. | Differentiated progeny of clonal progenitor cell lines |
ES2896354T3 (es) | 2012-12-21 | 2022-02-24 | Astellas Inst For Regenerative Medicine | Métodos para la producción de plaquetas a partir de células madre pluripotentes |
KR101870174B1 (ko) | 2013-05-31 | 2018-06-22 | 아이하트 재팬 가부시키가이샤 | 하이드로겔을 포함하는 적층화된 세포 시트 |
JP6529486B2 (ja) | 2013-06-05 | 2019-06-12 | バイオタイム インク.Biotime Inc. | 哺乳動物種における誘導組織再生のための組成物および方法 |
US11078462B2 (en) | 2014-02-18 | 2021-08-03 | ReCyte Therapeutics, Inc. | Perivascular stromal cells from primate pluripotent stem cells |
US10240127B2 (en) | 2014-07-03 | 2019-03-26 | ReCyte Therapeutics, Inc. | Exosomes from clonal progenitor cells |
IL258899B2 (en) | 2015-10-30 | 2024-03-01 | Univ California | Methods for producing T cells from stem cells and immunotherapy methods using T cells |
CA3007733A1 (en) | 2015-12-07 | 2017-06-15 | Biotime, Inc. | Methods for the re-derivation of diverse pluripotent stem cell-derived brown fat cells |
US11674952B2 (en) | 2016-02-24 | 2023-06-13 | The Rockefeller University | Embryonic cell-based therapeutic candidate screening systems, models for Huntington's Disease and uses thereof |
WO2018232079A1 (en) | 2017-06-14 | 2018-12-20 | Daley George Q | Hematopoietic stem and progenitor cells derived from hemogenic endothelial cells by episomal plasmid gene transfer |
CN112567021A (zh) | 2018-08-24 | 2021-03-26 | 日产化学株式会社 | 作为细胞培养的基底膜使用的聚合物的制造方法及细胞培养容器 |
CN111378613B (zh) * | 2018-12-27 | 2024-01-09 | 深圳华大生命科学研究院 | 一种两栖类动物细胞解离试剂盒 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5196315A (en) * | 1990-05-01 | 1993-03-23 | The Johns Hopkins University | Human neuronal cell line |
JPH0638742A (ja) * | 1992-04-06 | 1994-02-15 | N T Sci:Kk | 動物胚幹細胞の培養方法 |
US5453357A (en) | 1992-10-08 | 1995-09-26 | Vanderbilt University | Pluripotential embryonic stem cells and methods of making same |
US5874301A (en) | 1994-11-21 | 1999-02-23 | National Jewish Center For Immunology And Respiratory Medicine | Embryonic cell populations and methods to isolate such populations |
US5914268A (en) | 1994-11-21 | 1999-06-22 | National Jewish Center For Immunology & Respiratory Medicine | Embryonic cell populations and methods to isolate such populations |
US5843780A (en) * | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
WO1999027076A1 (en) | 1997-11-25 | 1999-06-03 | Arc Genomic Research | Pluripotent embryonic stem cells and methods of obtaining them |
DE19756864C5 (de) * | 1997-12-19 | 2014-07-10 | Oliver Brüstle | Neurale Vorläuferzellen, Verfahren zu ihrer Herstellung und ihre Verwendung zur Therapie von neuralen Defekten |
IL129966A (en) * | 1999-05-14 | 2009-12-24 | Technion Res & Dev Foundation | ISOLATED HUMAN EMBRYOID BODIES (hEB) DERIVED FROM HUMAN EMBRYONIC STEM CELLS |
US6280718B1 (en) * | 1999-11-08 | 2001-08-28 | Wisconsin Alumni Reasearch Foundation | Hematopoietic differentiation of human pluripotent embryonic stem cells |
US6602711B1 (en) | 2000-02-21 | 2003-08-05 | Wisconsin Alumni Research Foundation | Method of making embryoid bodies from primate embryonic stem cells |
-
2000
- 2000-02-21 US US09/510,444 patent/US6602711B1/en not_active Expired - Lifetime
-
2001
- 2001-02-20 KR KR1020027010830A patent/KR100812856B1/ko active IP Right Grant
- 2001-02-20 EP EP01910936A patent/EP1257634A2/en not_active Withdrawn
- 2001-02-20 CN CN01805291A patent/CN1404526A/zh active Pending
- 2001-02-20 MX MXPA02008054A patent/MXPA02008054A/es active IP Right Grant
- 2001-02-20 NZ NZ520700A patent/NZ520700A/en not_active IP Right Cessation
- 2001-02-20 CA CA002400158A patent/CA2400158C/en not_active Expired - Lifetime
- 2001-02-20 WO PCT/US2001/005252 patent/WO2001062899A2/en active IP Right Grant
- 2001-02-20 IL IL15117601A patent/IL151176A0/xx active IP Right Grant
- 2001-02-20 AU AU3849101A patent/AU3849101A/xx active Pending
- 2001-02-20 BR BR0108436-4 patent/BRPI0108436B8/pt not_active IP Right Cessation
- 2001-02-20 AU AU2001238491A patent/AU2001238491B2/en not_active Expired
- 2001-02-20 JP JP2001562673A patent/JP5339661B2/ja not_active Expired - Lifetime
-
2002
- 2002-08-20 NO NO20023949A patent/NO20023949L/no unknown
- 2002-08-20 IS IS6514A patent/IS6514A/is unknown
-
2003
- 2003-07-15 HK HK03105100.3A patent/HK1052951A1/zh unknown
- 2003-08-01 US US10/632,399 patent/US7220584B2/en not_active Expired - Lifetime
-
2006
- 2006-08-18 AU AU2006203588A patent/AU2006203588A1/en not_active Abandoned
-
2010
- 2010-10-14 IL IL208748A patent/IL208748A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CA2400158A1 (en) | 2001-08-30 |
CN1404526A (zh) | 2003-03-19 |
KR20030032921A (ko) | 2003-04-26 |
AU2006203588A1 (en) | 2006-09-07 |
IS6514A (is) | 2002-08-20 |
WO2001062899A3 (en) | 2002-02-21 |
CA2400158C (en) | 2006-04-04 |
WO2001062899A2 (en) | 2001-08-30 |
IL151176A0 (en) | 2003-04-10 |
US20040023376A1 (en) | 2004-02-05 |
MXPA02008054A (es) | 2003-01-28 |
IL208748A0 (en) | 2010-12-30 |
BRPI0108436B1 (pt) | 2021-02-23 |
NO20023949D0 (no) | 2002-08-20 |
HK1052951A1 (zh) | 2003-10-03 |
NZ520700A (en) | 2004-04-30 |
US7220584B2 (en) | 2007-05-22 |
BRPI0108436B8 (pt) | 2021-05-25 |
KR100812856B1 (ko) | 2008-03-11 |
JP2003523766A (ja) | 2003-08-12 |
JP5339661B2 (ja) | 2013-11-13 |
AU2001238491B2 (en) | 2006-05-18 |
US6602711B1 (en) | 2003-08-05 |
EP1257634A2 (en) | 2002-11-20 |
NO20023949L (no) | 2002-08-20 |
IL208748A (en) | 2015-01-29 |
AU3849101A (en) | 2001-09-03 |
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