BR0103241A - Dispositivo de cultura, e, processo para controlar espumas por desespumação com um dispositivo de cultura - Google Patents

Dispositivo de cultura, e, processo para controlar espumas por desespumação com um dispositivo de cultura

Info

Publication number
BR0103241A
BR0103241A BR0103241-0A BR0103241A BR0103241A BR 0103241 A BR0103241 A BR 0103241A BR 0103241 A BR0103241 A BR 0103241A BR 0103241 A BR0103241 A BR 0103241A
Authority
BR
Brazil
Prior art keywords
foams
culture device
liquid
vapor separation
culture
Prior art date
Application number
BR0103241-0A
Other languages
English (en)
Inventor
Atsushi Okada
Yoshitaka Teratani
Naohiro Kadota
Hisao Itoh
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of BR0103241A publication Critical patent/BR0103241A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/02—Means for regulation, monitoring, measurement or control, e.g. flow regulation of foam
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/02—Percolation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/20—Degassing; Venting; Bubble traps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Degasification And Air Bubble Elimination (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"DISPOSITIVO DE CULTURA, E, PROCESSO PARA CONTROLAR ESPUMAS POR DESESPUMAçãO COM UM DISPOSITIVO DE CULTURA". Um sensor detector de espuma (7) e uma corneta de oscilação ultra-sónica (13) são montadas sobre uma tubulação vertical entre o tanque de cultura (1) e um dispositivo (5) de separação de líquido-vapor. Quando as espumas que extravasam são submetidas a irradiação ultra-sónica, elas se rompem e perdem volume. As espumas rompidas têm alta densidade aparente, em comparação com as espumas antes da irradiação. Assim, o uso simultâneo dos dispositivos oscilador ultra-sónica (12, 13) e do dispositivo de separação de líquido-vapor (5), tal como o ciclone, conduz a uma eficiência de separação líquido-vapor intensificada, e produtividade mais elevada por fermentação.
BR0103241-0A 2000-08-08 2001-08-07 Dispositivo de cultura, e, processo para controlar espumas por desespumação com um dispositivo de cultura BR0103241A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000239836A JP4273643B2 (ja) 2000-08-08 2000-08-08 好気性培養における培養装置及び消泡制御方法

Publications (1)

Publication Number Publication Date
BR0103241A true BR0103241A (pt) 2002-03-19

Family

ID=18731311

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0103241-0A BR0103241A (pt) 2000-08-08 2001-08-07 Dispositivo de cultura, e, processo para controlar espumas por desespumação com um dispositivo de cultura

Country Status (7)

Country Link
US (1) US6465243B2 (pt)
EP (1) EP1179584B1 (pt)
JP (1) JP4273643B2 (pt)
AU (1) AU781773B2 (pt)
BR (1) BR0103241A (pt)
DE (1) DE60130714T2 (pt)
MY (1) MY118668A (pt)

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US7745210B2 (en) * 2006-06-30 2010-06-29 Corning Incorporated Fluid flow diverter for cell culture vessel
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CN101003780B (zh) * 2007-01-24 2011-12-14 王培生 安装有消沫器由罐顶中心排气的微生物发酵装置
US7897379B2 (en) * 2007-02-26 2011-03-01 Corning Incorporated Device and method for reducing bubble formation in cell culture
US9309491B2 (en) 2007-05-29 2016-04-12 Corning Incorporated Cell culture apparatus for co-culture of cells
EP2245453B1 (en) 2008-01-03 2016-10-05 EMD Millipore Corporation Microfluidic cell culture array system for automated assays and methods of operation
CN101285034B (zh) * 2008-06-06 2010-05-12 李明忠 多功能复合型生物发酵用阻沫回收装置
JP5326117B2 (ja) * 2008-08-25 2013-10-30 株式会社ＡＭＢｉＳ 消泡装置、培養システム及び消泡装置付き容器
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US9353342B2 (en) 2010-01-21 2016-05-31 Emd Millipore Corporation Cell culture and gradient migration assay methods and devices
CN101921703B (zh) * 2010-07-16 2013-07-10 李明忠 高效生物消沫器
CN102259064A (zh) * 2010-08-25 2011-11-30 鞍钢集团矿业公司 浮选泡沫消泡设备
US10526572B2 (en) 2011-04-01 2020-01-07 EMD Millipore Corporaticn Cell culture and invasion assay method and system
JP6232383B2 (ja) 2011-12-03 2017-11-15 イー・エム・デイー・ミリポア・コーポレイシヨン マイクロ流体の細胞培養のためのマイクロインキュベーションシステムおよび方法
JP6561071B2 (ja) * 2014-01-16 2019-08-14 ライフ テクノロジーズ コーポレイション 反応器気泡センサシステム及び使用方法
KR101538401B1 (ko) * 2014-02-24 2015-08-07 농업회사법인 마동이주식회사 발효 효율을 향상시킨 수세미오이 발효기
CN103952293B (zh) * 2014-05-04 2015-07-08 梁山菱花生物科技有限公司 一种利用超声波消泡的发酵罐空气分布器
CN103952294B (zh) * 2014-05-04 2015-07-08 梁山菱花生物科技有限公司 设有超声波发生装置的发酵罐
CN103952306B (zh) * 2014-05-04 2015-09-30 梁山菱花生物科技有限公司 一种使用超声波消泡的发酵罐
WO2016071691A1 (en) * 2014-11-07 2016-05-12 Oxy Solutions As Apparatus for dissolving gas into a liquid
US20170051245A1 (en) * 2015-08-19 2017-02-23 Ge Healthcare Bio-Sciences Corp. Passive automatic antifoam delivery system for use with single-use bioreactors
DE102015114510A1 (de) 2015-08-31 2017-03-02 Agraferm Technologies Ag Vorrichtung und Verringerung der Schaumbildung in einem Biogasfermenter
CN107022481A (zh) * 2017-06-01 2017-08-08 广西金茂生物化工有限公司 一种适用于发酵罐的除沫消泡器
JP6594462B2 (ja) * 2018-01-16 2019-10-23 月島機械株式会社 培養装置
KR101989348B1 (ko) 2018-03-02 2019-06-20 한국에너지기술연구원 생물반응기 내부의 폼을 제거하는 트랩 및 이를 사용하여 미생물 배양시 발생하는 폼을 제거하는 방법
CN109266530A (zh) * 2018-09-06 2019-01-25 常州大学 一种消泡分离装置
US11999937B2 (en) 2018-10-16 2024-06-04 Sartorius Stedim North America Inc. Foam mitigation in bioreactors using ultrasound
WO2020129342A1 (ja) * 2018-12-18 2020-06-25 積水化学工業株式会社 有機物質生成システム
JP7278097B2 (ja) * 2019-02-21 2023-05-19 三菱ケミカルエンジニアリング株式会社 超音波消泡手段を備えた微生物培養装置、およびこの微生物培養装置を用いた微生物培養方法
KR102179144B1 (ko) 2019-03-04 2020-11-16 한국에너지기술연구원 미생물 배양시 발생하는 폼을 제거하기 위한 장치 및 이를 사용하여 폼을 제거하는 방법
RU2728193C1 (ru) * 2019-06-11 2020-07-28 Общество с ограниченной ответственностью "Биопрактика" (ООО "Биопрактика") Ферментер и ферментационная установка для непрерывного культивирования микроорганизмов
CN110938535B (zh) * 2019-11-25 2023-03-21 郑州职业技术学院 一种生防放线菌发酵罐
CN114100286A (zh) * 2021-11-11 2022-03-01 濮阳泓天威药业有限公司 一种生物发酵逃液收集装置

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Also Published As

Publication number Publication date
MY118668A (en) 2004-12-31
DE60130714D1 (de) 2007-11-15
EP1179584B1 (en) 2007-10-03
AU781773B2 (en) 2005-06-09
JP4273643B2 (ja) 2009-06-03
US6465243B2 (en) 2002-10-15
JP2002051763A (ja) 2002-02-19
AU5779501A (en) 2002-02-14
DE60130714T2 (de) 2008-04-30
EP1179584A1 (en) 2002-02-13
US20020039784A1 (en) 2002-04-04

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A(S) 10A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2112 DE 28/06/2011.