BR0103059A - Processo para a preparação de pirazóis - Google Patents

Processo para a preparação de pirazóis

Info

Publication number
BR0103059A
BR0103059A BR0103059-0A BR0103059A BR0103059A BR 0103059 A BR0103059 A BR 0103059A BR 0103059 A BR0103059 A BR 0103059A BR 0103059 A BR0103059 A BR 0103059A
Authority
BR
Brazil
Prior art keywords
general formula
reaction
compound
preparing pyrazoles
pirazóis
Prior art date
Application number
BR0103059-0A
Other languages
English (en)
Inventor
Laurence James Harris
Philip Charles Levett
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0018662A external-priority patent/GB0018662D0/en
Priority claimed from GB0106276A external-priority patent/GB0106276D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of BR0103059A publication Critical patent/BR0103059A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Patente de Invenção: "PROCESSO PARA A PREPARAçãO DE PIRAZóIS". é aqui proporcionado um processo para a produção de compostos de pirazól da fórmula geral (II): em que R^ P^ representa H ou R^ 1^; processo esse que compreende a reação do composto de fórmula geral (III), em que R^ 11a^ e R^ 11b^ independentemente representam C~ 1~-C~ 6~ alquila, R^ 2^ é como aqui definido anteriormente, com um agente acilante na presença de uma base, seguido de reação in situ com um composto de hidrazina em que o referido processo é realizado opcionalmente na presença de um agente ativante.
BR0103059-0A 2000-07-28 2001-07-27 Processo para a preparação de pirazóis BR0103059A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0018662A GB0018662D0 (en) 2000-07-28 2000-07-28 Novel process for the preparation of pyrazoles
GB0106276A GB0106276D0 (en) 2001-03-14 2001-03-14 Novel process for the preparation of pyrazoles

Publications (1)

Publication Number Publication Date
BR0103059A true BR0103059A (pt) 2002-03-12

Family

ID=26244759

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0103059-0A BR0103059A (pt) 2000-07-28 2001-07-27 Processo para a preparação de pirazóis

Country Status (5)

Country Link
EP (1) EP1176142A1 (pt)
JP (1) JP2002193941A (pt)
BR (1) BR0103059A (pt)
CA (1) CA2354173C (pt)
MX (1) MXPA01007674A (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
OA13050A (en) 2003-04-29 2006-11-10 Pfizer Ltd 5,7-diaminopyrazolo [4,3-D] pyrimidines useful in the treatment of hypertension.
US7572799B2 (en) 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
ATE417849T1 (de) 2004-04-07 2009-01-15 Pfizer Pyrazoloä4,3-düpyrimidine
CN102267986B (zh) * 2011-09-01 2014-04-16 中国农业大学 一种吡唑双酰胺类化合物及其合成方法与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9013750D0 (en) * 1990-06-20 1990-08-08 Pfizer Ltd Therapeutic agents
GB9612514D0 (en) * 1996-06-14 1996-08-14 Pfizer Ltd Novel process
EP0977756A1 (en) * 1997-04-25 2000-02-09 Pfizer Limited PYRAZOLOPYRIMIDINONES WHICH INHIBIT TYPE 5 CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASE (cGMP PDE5) FOR THE TREATMENT OF SEXUAL DYSFUNCTION
PL343794A1 (en) * 1998-04-20 2001-09-10 Pfizer Pyrazolopyrimidinone cgmp pde5 inhibitors for the treatment of sexual dysfunction
GB9822238D0 (en) * 1998-10-12 1998-12-09 Pfizer Ltd Process for preparation of pyrazolo[4,3-D]pyrimidin-7-ones and intermediates thereof
GB9823101D0 (en) * 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
TWI265925B (en) * 1999-10-11 2006-11-11 Pfizer Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
CN1378547A (zh) * 1999-10-11 2002-11-06 辉瑞大药厂 用作磷酸二酯酶抑制剂的5－(2－取代的－5－杂环基磺酰基吡啶－3－基)－二氢吡唑并[4,3－d]嘧啶－7－酮类化合物

Also Published As

Publication number Publication date
EP1176142A1 (en) 2002-01-30
CA2354173C (en) 2005-12-27
CA2354173A1 (en) 2002-01-28
MXPA01007674A (es) 2002-10-23
JP2002193941A (ja) 2002-07-10

Similar Documents

Publication Publication Date Title
BR9917518A (pt) Processos para a preparação de pestecidas 1-arilpirazóis e seus intermediários
HN2006019068A (es) "sintesis de (r)-n-metilnaltrexona"
GT200200145A (es) Nuevos compuestos fungicidas
PL369530A1 (en) Chemical compounds
BRPI9917739B8 (pt) composto intermediário na preparação de inibidores de cox-2
CO5560574A2 (es) Procesos para la preparacion de compuestos de aminopirimidina, halogenopirimidina, sulfoniloxipirimidina e hidroxipirimidina; y un compuesto de hidroxipirimidina
GT200400107A (es) Fungicidas
PE20061447A1 (es) Tigeciclina y metodos para preparar 9-aminominociclina
BR0211204A (pt) Processo e intermediários para preparar latanoprost
ATE302813T1 (de) Fein verteilte stabilisatorzusammensetzung für halogenhaltige polymere
BR0103059A (pt) Processo para a preparação de pirazóis
DK1706414T3 (da) Fremgangsmåde til fluorcytidinderivater
UA93860C2 (ru) Способ получения пиразолов, способ региоселективного алкилирования и применение фосфата или фосфоната b способе
BRPI0108990B8 (pt) processo para preparação de derivados de pirimidona com atividade antifungos
DE60309251D1 (de) Verfahren zur Herstellung von Donepezil
BR0112880B1 (pt) composto de pirazol, agente de controle de peste compreendendo o mesmo como ingrediente ativo e processo para produÇço do mesmo.
BRPI0508602A (pt) processo para a preparação de compostos, e, compostos de hidrazona
AR039719A1 (es) Derivados de ftalamida
BR0215306A (pt) Uso de deoxipeganina
DE602006008836D1 (de) Reaktionsprodukt von Resorcin und Methylethylketon
BR0113170A (pt) Processo para a preparação de dinapsolina
BRPI0408754A (pt) processo para combater fungos fitopatogênicos nocivos, compostos, processo para preparar os mesmos, e, agente adequado para combater fungos nocivos
MX2009013336A (es) Sintesis de 3-aminopirazoles sustituidos.
DE60110975D1 (de) Acylierungsverfahren
BR0209852A (pt) método para a produção de biperideno, e, composto

Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 6A , 7A E 8A ANUIDADES.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2012 DE 28/07/2009.