BR0015779A - Composição efervescente antagonista h2 da histamina - Google Patents

Composição efervescente antagonista h2 da histamina

Info

Publication number
BR0015779A
BR0015779A BR0015779-1A BR0015779A BR0015779A BR 0015779 A BR0015779 A BR 0015779A BR 0015779 A BR0015779 A BR 0015779A BR 0015779 A BR0015779 A BR 0015779A
Authority
BR
Brazil
Prior art keywords
acidulant
antagonist
composition
effervescent
histamine
Prior art date
Application number
BR0015779-1A
Other languages
English (en)
Inventor
Mamoun M Hussein
John Migton
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of BR0015779A publication Critical patent/BR0015779A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"COMPOSIçãO EFERVESCENTE ANTAGONISTA H~ 2~ DA HISTAMINA". Um antagonista H~ 2~ da histamina incompatível com materiais ácidos é incorporado em uma composição efervescente e é estável nela contanto que o acidulante empregado no par efervescente seja um acidulante contendo um grupo não-hidroxila e tal acidulante seja empregado como substancialmente a quantidade completa de acidulante presente na formulação. Preferivelmente, a composição é desprovida de acidulante contendo grupo hidroxila. O ácido adípico, ácido succínico, ácido fumárico e o anidrido succínico podem ser empregados como o acidulante. O ácido adípico é o preferido.
BR0015779-1A 1999-12-06 2000-11-16 Composição efervescente antagonista h2 da histamina BR0015779A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/455,233 US6264984B1 (en) 1999-12-06 1999-12-06 Effervescent histamine H2 antagonist composition
PCT/US2000/031360 WO2001039750A1 (en) 1999-12-06 2000-11-16 Effervescent histamine h2 antagonist composition

Publications (1)

Publication Number Publication Date
BR0015779A true BR0015779A (pt) 2002-07-09

Family

ID=23807966

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0015779-1A BR0015779A (pt) 1999-12-06 2000-11-16 Composição efervescente antagonista h2 da histamina

Country Status (18)

Country Link
US (1) US6264984B1 (pt)
EP (1) EP1237543B1 (pt)
JP (1) JP2003515553A (pt)
KR (1) KR100795259B1 (pt)
CN (1) CN1211077C (pt)
AR (1) AR030172A1 (pt)
AT (1) ATE309783T1 (pt)
AU (1) AU1766101A (pt)
BR (1) BR0015779A (pt)
CA (1) CA2394902C (pt)
CY (1) CY1105495T1 (pt)
DE (1) DE60024132T2 (pt)
DK (1) DK1237543T3 (pt)
ES (1) ES2252078T3 (pt)
MX (1) MXPA02005534A (pt)
PE (1) PE20010909A1 (pt)
WO (1) WO2001039750A1 (pt)
ZA (1) ZA200203168B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070154542A1 (en) * 2005-12-30 2007-07-05 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
US9717726B2 (en) * 2013-03-14 2017-08-01 Maregade Rx, LLC Product and method for treating diarrhea
WO2015157729A1 (en) * 2014-04-11 2015-10-15 Wilmink Michael Pharmaceutical formulations an comprising analgesic agent, a nonsteroidal anti-inflammatory agent, a gastric acid production suppressant and an anti-nauseant
CN105997922A (zh) * 2016-06-12 2016-10-12 佛山市腾瑞医药科技有限公司 一种盐酸雷尼替丁泡腾片及其制备方法
EP3558296B1 (en) 2016-12-23 2023-06-28 Maregade RX, LLC Low dose product and method for treating diarrhea

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2593065B1 (fr) 1986-01-22 1988-09-09 Smith Kline French Lab Couples effervescents, compositions effervescentes d'antagonistes h2 de l'histamine les contenant et leur preparation.
FR2633181B1 (fr) 1988-06-24 1992-01-10 Glaxo Lab Sa Composition pharmaceutique a base de ranitidine et son procede de preparation
DE4027927A1 (de) * 1990-09-04 1992-03-05 Bayer Ag Brausekomponente und verfahren zu ihrer herstellung
CA2061520C (en) 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
US5503846A (en) * 1993-03-17 1996-04-02 Cima Labs, Inc. Base coated acid particles and effervescent formulation incorporating same
ES2126147T3 (es) 1993-09-09 1999-03-16 Gerhard Gergely Granulado efervescente y procedimiento para su preparacion.
WO1995010274A1 (en) 1993-10-14 1995-04-20 F.H. Faulding & Co. Limited Aqueous pharmaceutical composition
IL112779A (en) 1994-03-01 1999-11-30 Gergely Gerhard Granular product or tablet containing an efferescent system and an active pharmaceutical substance and its preparation
ES2136157T3 (es) 1994-03-01 1999-11-16 Gerhard Gergely Producto granular o comprimido que contiene un sistema efervescente y una sustancia farmaceutica activa, asi como un procedimiento para su preparacion.
US5824339A (en) 1995-09-08 1998-10-20 Takeda Chemical Industries, Ltd Effervescent composition and its production
US5728401A (en) * 1997-04-16 1998-03-17 Ranbaxy Laboratories, Ltd. Effervescent ranitidine formulations

Also Published As

Publication number Publication date
MXPA02005534A (es) 2002-11-29
WO2001039750A1 (en) 2001-06-07
DE60024132T2 (de) 2006-08-03
DE60024132D1 (de) 2005-12-22
EP1237543B1 (en) 2005-11-16
AU1766101A (en) 2001-06-12
EP1237543A1 (en) 2002-09-11
US6264984B1 (en) 2001-07-24
KR20020070309A (ko) 2002-09-05
CA2394902A1 (en) 2001-06-07
CY1105495T1 (el) 2010-04-28
DK1237543T3 (da) 2006-01-16
ZA200203168B (en) 2003-09-23
AR030172A1 (es) 2003-08-13
CN1211077C (zh) 2005-07-20
JP2003515553A (ja) 2003-05-07
CN1407885A (zh) 2003-04-02
CA2394902C (en) 2006-08-08
ATE309783T1 (de) 2005-12-15
PE20010909A1 (es) 2001-11-11
ES2252078T3 (es) 2006-05-16
KR100795259B1 (ko) 2008-01-15
EP1237543A4 (en) 2004-06-30

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements