BR0015491A - Métodos para tratar um distúrbio proliferativo celular mediado por ras em um mamìfero, para tratar um neoplasma tendo uma via-ras ativada em um humano, para inibir metástase de um neoplasma tendo uma via-ras ativada em um mamìfero, e para tratar um neoplasma suspeito de ter uma via-ras ativada em um mamìfero, composição farmacêutica, kit, e, método para tratar uma população de células compreendendo um neoplasma suspeito de ter uma via-ras ativada in vitro - Google Patents
Métodos para tratar um distúrbio proliferativo celular mediado por ras em um mamìfero, para tratar um neoplasma tendo uma via-ras ativada em um humano, para inibir metástase de um neoplasma tendo uma via-ras ativada em um mamìfero, e para tratar um neoplasma suspeito de ter uma via-ras ativada em um mamìfero, composição farmacêutica, kit, e, método para tratar uma população de células compreendendo um neoplasma suspeito de ter uma via-ras ativada in vitroInfo
- Publication number
- BR0015491A BR0015491A BR0015491-1A BR0015491A BR0015491A BR 0015491 A BR0015491 A BR 0015491A BR 0015491 A BR0015491 A BR 0015491A BR 0015491 A BR0015491 A BR 0015491A
- Authority
- BR
- Brazil
- Prior art keywords
- activated
- neoplasm
- pathway
- treat
- mammal
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 8
- 208000035269 cancer or benign tumor Diseases 0.000 title abstract 7
- 230000002062 proliferating effect Effects 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 5
- 230000037361 pathway Effects 0.000 title abstract 5
- 206010027476 Metastases Diseases 0.000 title abstract 2
- 230000009401 metastasis Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 title 3
- 238000000338 in vitro Methods 0.000 title 1
- 230000001404 mediated effect Effects 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 3
- 241000700635 Orf virus Species 0.000 abstract 1
- 241000700618 Vaccinia virus Species 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 229940125721 immunosuppressive agent Drugs 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 238000010030 laminating Methods 0.000 abstract 1
- 241000701161 unidentified adenovirus Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/761—Adenovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16487899P | 1999-11-12 | 1999-11-12 | |
| PCT/CA2000/001329 WO2001035970A1 (en) | 1999-11-12 | 2000-11-08 | Viruses for the treatment of cellular proliferative disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0015491A true BR0015491A (pt) | 2002-10-15 |
Family
ID=22596481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0015491-1A BR0015491A (pt) | 1999-11-12 | 2000-11-08 | Métodos para tratar um distúrbio proliferativo celular mediado por ras em um mamìfero, para tratar um neoplasma tendo uma via-ras ativada em um humano, para inibir metástase de um neoplasma tendo uma via-ras ativada em um mamìfero, e para tratar um neoplasma suspeito de ter uma via-ras ativada em um mamìfero, composição farmacêutica, kit, e, método para tratar uma população de células compreendendo um neoplasma suspeito de ter uma via-ras ativada in vitro |
Country Status (11)
| Country | Link |
|---|---|
| US (9) | US6596268B1 (enExample) |
| EP (2) | EP1227828A1 (enExample) |
| JP (1) | JP2003514024A (enExample) |
| AU (1) | AU782020B2 (enExample) |
| BR (1) | BR0015491A (enExample) |
| CA (2) | CA2720361A1 (enExample) |
| HK (1) | HK1047698A1 (enExample) |
| MX (1) | MXPA02004736A (enExample) |
| NZ (1) | NZ518454A (enExample) |
| WO (1) | WO2001035970A1 (enExample) |
| ZA (1) | ZA200203041B (enExample) |
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| AU3001799A (en) * | 1998-03-12 | 1999-09-27 | Trustees Of The University Of Pennsylvania, The | Producer cells for replication selective viruses in the treatment of malignancy |
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| AU4582899A (en) | 1998-06-22 | 2000-01-10 | Board Of Trustees Of The University Of Arkansas, The | Mutated herpes simplex virus type 1 thymidine kinases and uses thereof |
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-
2000
- 2000-11-08 EP EP00974225A patent/EP1227828A1/en not_active Ceased
- 2000-11-08 CA CA2720361A patent/CA2720361A1/en not_active Abandoned
- 2000-11-08 HK HK02108779.8A patent/HK1047698A1/zh unknown
- 2000-11-08 MX MXPA02004736A patent/MXPA02004736A/es active IP Right Grant
- 2000-11-08 NZ NZ518454A patent/NZ518454A/en unknown
- 2000-11-08 BR BR0015491-1A patent/BR0015491A/pt not_active Application Discontinuation
- 2000-11-08 ZA ZA200203041A patent/ZA200203041B/en unknown
- 2000-11-08 CA CA2388807A patent/CA2388807C/en not_active Expired - Lifetime
- 2000-11-08 JP JP2001537962A patent/JP2003514024A/ja active Pending
- 2000-11-08 AU AU12626/01A patent/AU782020B2/en not_active Expired
- 2000-11-08 EP EP08009283A patent/EP1955703A1/en not_active Ceased
- 2000-11-08 WO PCT/CA2000/001329 patent/WO2001035970A1/en not_active Ceased
- 2000-11-09 US US09/708,663 patent/US6596268B1/en not_active Expired - Lifetime
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2001
- 2001-09-28 US US09/965,294 patent/US6649157B2/en not_active Expired - Lifetime
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2003
- 2003-04-18 US US10/418,290 patent/US7252817B2/en not_active Expired - Lifetime
-
2006
- 2006-11-07 US US11/557,467 patent/US7731951B2/en not_active Expired - Fee Related
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2007
- 2007-05-30 US US11/807,770 patent/US7799329B2/en not_active Expired - Fee Related
- 2007-05-30 US US11/807,906 patent/US7582289B2/en not_active Expired - Lifetime
- 2007-05-30 US US11/807,920 patent/US7964186B2/en not_active Expired - Fee Related
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2010
- 2010-04-16 US US12/761,534 patent/US8080241B2/en not_active Expired - Fee Related
-
2011
- 2011-11-16 US US13/297,384 patent/US8491886B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6596268B1 (en) | 2003-07-22 |
| US20070086984A1 (en) | 2007-04-19 |
| WO2001035970A1 (en) | 2001-05-25 |
| US7731951B2 (en) | 2010-06-08 |
| US20080019981A1 (en) | 2008-01-24 |
| JP2003514024A (ja) | 2003-04-15 |
| US8491886B2 (en) | 2013-07-23 |
| US20100203147A1 (en) | 2010-08-12 |
| US20120156168A1 (en) | 2012-06-21 |
| AU782020B2 (en) | 2005-06-30 |
| ZA200203041B (en) | 2003-12-09 |
| US7964186B2 (en) | 2011-06-21 |
| US7799329B2 (en) | 2010-09-21 |
| US20080019980A1 (en) | 2008-01-24 |
| MXPA02004736A (es) | 2003-01-28 |
| HK1047698A1 (zh) | 2003-03-07 |
| US7582289B2 (en) | 2009-09-01 |
| AU1262601A (en) | 2001-05-30 |
| US20040057929A1 (en) | 2004-03-25 |
| US6649157B2 (en) | 2003-11-18 |
| EP1227828A1 (en) | 2002-08-07 |
| CA2388807A1 (en) | 2001-05-25 |
| US8080241B2 (en) | 2011-12-20 |
| EP1955703A1 (en) | 2008-08-13 |
| CA2388807C (en) | 2013-08-06 |
| US20080031886A1 (en) | 2008-02-07 |
| CA2720361A1 (en) | 2001-05-25 |
| US20020028195A1 (en) | 2002-03-07 |
| US7252817B2 (en) | 2007-08-07 |
| NZ518454A (en) | 2004-07-30 |
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