BR0010495A - Derivado da imidazodiazepina - Google Patents

Derivado da imidazodiazepina

Info

Publication number
BR0010495A
BR0010495A BR0010495-7A BR0010495A BR0010495A BR 0010495 A BR0010495 A BR 0010495A BR 0010495 A BR0010495 A BR 0010495A BR 0010495 A BR0010495 A BR 0010495A
Authority
BR
Brazil
Prior art keywords
imidazodiazepine
derived
compound
midazo
benzodiazepin
Prior art date
Application number
BR0010495-7A
Other languages
English (en)
Inventor
Francois Jenck
Fabienne Hoffmann-Emery
Walter Hunkeler
James Richard Martin
Andrews Leight
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR0010495A publication Critical patent/BR0010495A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Patente de Invenção: "DERIVADO DA IMIDAZODIAZEPINA". A presente invenção refere-se ao composto 7-cloro-3-(5-dimetilaminometil-[1,2,4]oxadiazol-3-il)-5-metil-4,5-diidro-i midazo[1,5-a][1,4]benzodiazepin-6-ona (I) e ao uso do composto de fórmula (I) para a fabricação de medicamentos para serem usados como medicamentos ansiolíticos e/ou anticonvulsivos e/ou indutores do sono não-sedativos.
BR0010495-7A 1999-05-12 2000-05-05 Derivado da imidazodiazepina BR0010495A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99109513 1999-05-12
PCT/EP2000/004034 WO2000069858A1 (en) 1999-05-12 2000-05-05 Imidazodiazepine derivative

Publications (1)

Publication Number Publication Date
BR0010495A true BR0010495A (pt) 2002-02-13

Family

ID=8238165

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0010495-7A BR0010495A (pt) 1999-05-12 2000-05-05 Derivado da imidazodiazepina

Country Status (17)

Country Link
US (1) US6391873B1 (pt)
EP (1) EP1178990B1 (pt)
JP (1) JP3706307B2 (pt)
KR (1) KR100451610B1 (pt)
CN (1) CN1164590C (pt)
AR (1) AR023884A1 (pt)
AT (1) ATE231865T1 (pt)
AU (1) AU769666B2 (pt)
BR (1) BR0010495A (pt)
CA (1) CA2372040C (pt)
DE (1) DE60001313T2 (pt)
DK (1) DK1178990T3 (pt)
ES (1) ES2189759T3 (pt)
MX (1) MXPA01011449A (pt)
TR (1) TR200103237T2 (pt)
WO (1) WO2000069858A1 (pt)
ZA (1) ZA200108913B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5180077B2 (ja) 2006-08-11 2013-04-10 パナソニック株式会社 複数ドライブ装置の遅延対策と省電力制御を行う記録再生装置
EP2190435B1 (en) * 2007-08-20 2018-05-30 Evotec International GmbH Treatment of sleep disorders
WO2009024324A2 (en) * 2007-08-20 2009-02-26 Evotec Neurosciences Gmbh Treatment of sleep disorders
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
PL2252581T3 (pl) * 2008-01-22 2012-10-31 Lilly Co Eli Selektywny antagonista receptora opioidowego kappa
CN107007559B (zh) * 2017-04-21 2020-05-15 浙江京新药业股份有限公司 一种稳定的口服药物组合物及其制备方法
CN109134471B (zh) * 2017-06-27 2020-05-15 浙江京新药业股份有限公司 一种苯并二氮杂*化合物的固态形式及其制备方法和应用
CN112778220B (zh) * 2019-11-02 2024-06-07 浙江京新药业股份有限公司 一种苯并二氮杂䓬二酮化合物d的制备方法及其中间体
CN113045574B (zh) * 2019-12-26 2024-06-07 浙江京新药业股份有限公司 二氮杂䓬衍生物的制备方法及其中间体
US20220370409A1 (en) 2021-05-04 2022-11-24 Janssen Pharmaceuticals, Inc. Compositions And Methods For The Treatment Of Depression
WO2023170550A1 (en) 2022-03-07 2023-09-14 Janssen Pharmaceuticals, Inc. Polymorph forms of aticaprant for use in treating major depressive disorder

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2143246C (en) 1994-03-16 2000-08-22 Thierry Godel Imidazodiazepines
TR199700587T1 (xx) * 1995-01-06 1998-02-21 F. Hoffmann-La Roche Ag Hidroksimetil-imidazodiazepin ve bunlar�n esterleri.

Also Published As

Publication number Publication date
CN1350538A (zh) 2002-05-22
AR023884A1 (es) 2002-09-04
DE60001313D1 (en) 2003-03-06
MXPA01011449A (es) 2002-06-04
DK1178990T3 (da) 2003-05-26
AU5211400A (en) 2000-12-05
KR20010112487A (ko) 2001-12-20
DE60001313T2 (de) 2004-01-22
ES2189759T3 (es) 2003-07-16
KR100451610B1 (ko) 2004-10-06
EP1178990A1 (en) 2002-02-13
JP3706307B2 (ja) 2005-10-12
ATE231865T1 (de) 2003-02-15
EP1178990B1 (en) 2003-01-29
AU769666B2 (en) 2004-01-29
ZA200108913B (en) 2003-03-26
CA2372040A1 (en) 2000-11-23
JP2002544277A (ja) 2002-12-24
CA2372040C (en) 2008-12-02
CN1164590C (zh) 2004-09-01
WO2000069858A1 (en) 2000-11-23
US6391873B1 (en) 2002-05-21
TR200103237T2 (tr) 2002-04-22

Similar Documents

Publication Publication Date Title
TR200000197T2 (tr) Yeni bileşimler
NL350075I2 (pt)
HK1008222A1 (en) Pyrrolopyrimidines and processes for the preparation thereof
TW200617013A (en) Diazabicyclic central nervous system active agents
TR200101567T2 (tr) Yeni triazolo(4.5-D)pirimidin bileşimleri.
ATE320436T1 (de) Dimere pyrrolobenzodiazepine
BR0317483A (pt) Derivados de benzodiazepina para o tratamento de desordens neurológicas
DE69710490T2 (de) Triazolo(4,5-d)pyrimidinyl-derivate und ihre verwendung als medikamente
WO2000012504A3 (de) Dihydro-[1,2,3]triazolo-[4,5-d]pyrimidin-7-on
BR0010495A (pt) Derivado da imidazodiazepina
BR9913975A (pt) Agentes farmacêuticos para o tratamento da doença de parkinson, adhd e microadenomas
TR200402342T4 (tr) 2-Pirindinil-6,7,8,9- Tetrahidropyrimido[1,2-A] Pirimidin-4-On ve 7-Pirindinil-1,3-Dihydoimidazo[1,2-A]Pirimidin-5(1H) on Türevleri
SE9904129D0 (sv) Novel compounds
EE200100377A (et) Imidaso[1,5-a]-pürido[3,2-e]-pürasinoonide kasutamine arstimitena
BR0114379A (pt) Derivados de c-ciclohexilmetilamina substituìdos
WO2002010152A3 (de) Neue indolderivate und deren verwendung als arzneimittel
MXPA03003923A (es) Compuestos de n-([1,2,4]triazoloazinil)tiofensulfonamida como herbicidas.
UY26426A1 (es) Nuevos compuestos
DE60008400D1 (de) Triazolopyrimidinderivate
BRPI0409570A (pt) derivados de 3-benzidrilideno-8-aza-biciclo[3.2.1]octano com atividade receptora de opióides
ATE251162T1 (de) Triazolo(4,5-d)pyrimidin-verbindungen
DE50114335D1 (de) Lh-rh-antagonisten, deren herstellung und verwendung als arzneimittel
BR0010499A (pt) Agentes endoparasiticidas
BR0112092A (pt) 2-aminoalquiltieno[2,3-d]pirimidinas
DE50205888D1 (de) Pyrazolyl-substituierte triazolochinoxaline

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O E 11 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]