BR0009640A - Vìrus de herpes recombinantes e mutantes - Google Patents
Vìrus de herpes recombinantes e mutantesInfo
- Publication number
- BR0009640A BR0009640A BR0009640-7A BR0009640A BR0009640A BR 0009640 A BR0009640 A BR 0009640A BR 0009640 A BR0009640 A BR 0009640A BR 0009640 A BR0009640 A BR 0009640A
- Authority
- BR
- Brazil
- Prior art keywords
- recombinant
- herpes viruses
- foreign dna
- present
- mutant herpes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16341—Use of virus, viral particle or viral elements as a vector
- C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Patente de Invenção: "VìRUS DE HERPES RECOMBINANTES E MUTANTES". A presente invenção proporciona métodos e reagentes para induzir imunidade ativa em animais. Em particular, a presente invenção proporciona vírus de herpes recombinantes que apresentam DNA estranho os quais são capazes de induzir imunidade ao vírus de herpes e/ou à fonte do DNA estranho. A presente invenção também proporciona vírus de herpes mutante que apresentam porções de seu genoma suprimidas. Preferencialmente, DNA estranho é introduzido, ou porções do genoma são suprimidas, na estrutura de leitura aberta UL54.5 de um vírus de herpes de aves ou na estrutura de leitura aberta UL43 de vírus da doença de Marek.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/289,254 US6299882B1 (en) | 1999-04-09 | 1999-04-09 | UL54.5 of Marek's disease virus (MDV) |
PCT/US2000/009518 WO2000061736A2 (en) | 1999-04-09 | 2000-04-07 | Recombinant and mutant marek's disease virus |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0009640A true BR0009640A (pt) | 2002-03-05 |
Family
ID=23110719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0009640-7A BR0009640A (pt) | 1999-04-09 | 2000-04-07 | Vìrus de herpes recombinantes e mutantes |
Country Status (9)
Country | Link |
---|---|
US (1) | US6299882B1 (pt) |
EP (1) | EP1171608A2 (pt) |
JP (2) | JP2002541797A (pt) |
AU (1) | AU4223900A (pt) |
BR (1) | BR0009640A (pt) |
CA (1) | CA2366541C (pt) |
MX (1) | MXPA01010273A (pt) |
WO (1) | WO2000061736A2 (pt) |
ZA (1) | ZA200108263B (pt) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6913751B2 (en) | 1992-06-12 | 2005-07-05 | Schering-Plough Veterinary Corporation | Recombinant avian herpesvirus useful in vaccine production |
EP1178111A1 (en) | 2000-08-03 | 2002-02-06 | Lohmann Animal Health GmbH & Co. KG | Vaccination against host cell-associated herpesviruses |
US7314715B2 (en) | 2001-06-14 | 2008-01-01 | Schering-Plough Animal Health Corporation | Recombinant avian herpesvirus useful in vaccine production |
AU2003239589A1 (en) | 2002-05-24 | 2003-12-12 | Schering-Plough Ltd. | Eta-1 gene and methods for use |
CN101135762A (zh) * | 2006-09-01 | 2008-03-05 | 深圳富泰宏精密工业有限公司 | 镜头组件及其制造方法 |
EP2629794B1 (en) * | 2010-10-18 | 2017-06-07 | Intervet International B.V. | Herpesvirus of turkeys vectored vaccine against avian influenza in poultry |
CN103890183A (zh) * | 2011-10-21 | 2014-06-25 | 英特维特国际股份有限公司 | 编码传染性喉气管炎病毒和新城疫病毒抗原的重组非致病性马立克氏病病毒构建体 |
BR112014008161A2 (pt) | 2011-10-21 | 2017-04-11 | Intervet Int Bv | vírus da doença de marek não patogênico recombinante, método para a preparação do mesmo, molécula do ácido nucleico, célula hospedeira, vacina para aves domésticas, método para a preparação de uma vacina, uso de um vírus da doença de marek não patogênico recombinante, e, método de vacinação de aves domésticas |
US9114108B2 (en) | 2011-11-30 | 2015-08-25 | Merial, Inc. | Recombinant HVT vectors expressing antigens of avian pathogens and uses thereof |
ME03433B (me) | 2011-11-30 | 2020-01-20 | Merial Inc | REKOMBINANTNI VEKTORI GALLID HERPESVIRUSA 3 (MDV SEROTIP 2) KOJI EKSPRIMIRAJU ANTIGENE PTIČJIH PATHOGENA l NJIHOVE UPOTREBE |
US9950059B2 (en) * | 2014-02-25 | 2018-04-24 | The United States Of America, As Represented By The Secretary Of Agriculture. | Immunogenic composition |
US11596687B2 (en) | 2016-06-17 | 2023-03-07 | Intervet Inc. | Recombinant non-pathogenic Marek's disease virus constructs encoding infectious laryngotracheitis virus and infectious bursal disease virus antigens |
ES2936117T3 (es) | 2016-12-14 | 2023-03-14 | Boehringer Ingelheim Animal Health Usa Inc | Vectores recombinantes de VHT que expresan múltiples antígenos de patógenos aviares y vacunas que los comprenden |
US11229698B2 (en) | 2017-10-12 | 2022-01-25 | Intervet Inc. | Recombinant non-pathogenic Marek's Disease virus constructs encoding multiple heterologous antigens |
WO2019179966A1 (en) * | 2018-03-19 | 2019-09-26 | Boehringer Ingelheim Vetmedica Gmbh | Ehv insertion site ul43 |
WO2020093984A1 (en) * | 2018-11-06 | 2020-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Immunogenic composition against avian influenza virus h5 subtype |
KR20220056241A (ko) | 2019-09-11 | 2022-05-04 | 조에티스 서비시즈 엘엘씨 | 조류 병원체의 항원을 발현하는 재조합 칠면조 헤르페스바이러스 벡터 및 이의 용도 |
MX2022016337A (es) | 2020-06-17 | 2023-04-10 | Boehringer Ingelheim Vetmedica Gmbh | Vectores de hvt recombinantes que expresan hemaglutinina de influenza y composiciones inmunogenicas, su produccion y usos. |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5965138A (en) * | 1985-09-06 | 1999-10-12 | Syntro Corporation | Recombinant chimeric virus and uses thereof |
CA1319101C (en) | 1986-09-03 | 1993-06-15 | Marta Iris Sabara | Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules |
US5151267A (en) | 1988-07-15 | 1992-09-29 | University Of Saskatchewan | Bovine herpesvirus type 1 polypeptides and vaccines |
US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
US5853733A (en) * | 1993-02-26 | 1998-12-29 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
-
1999
- 1999-04-09 US US09/289,254 patent/US6299882B1/en not_active Expired - Lifetime
-
2000
- 2000-04-07 CA CA2366541A patent/CA2366541C/en not_active Expired - Fee Related
- 2000-04-07 AU AU42239/00A patent/AU4223900A/en not_active Abandoned
- 2000-04-07 BR BR0009640-7A patent/BR0009640A/pt not_active Application Discontinuation
- 2000-04-07 JP JP2000611660A patent/JP2002541797A/ja active Pending
- 2000-04-07 WO PCT/US2000/009518 patent/WO2000061736A2/en active Application Filing
- 2000-04-07 MX MXPA01010273A patent/MXPA01010273A/es active IP Right Grant
- 2000-04-07 EP EP00921990A patent/EP1171608A2/en not_active Ceased
-
2001
- 2001-10-08 ZA ZA200108263A patent/ZA200108263B/xx unknown
-
2010
- 2010-03-18 JP JP2010063199A patent/JP2010187679A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU4223900A (en) | 2000-11-14 |
WO2000061736A3 (en) | 2001-02-01 |
JP2002541797A (ja) | 2002-12-10 |
ZA200108263B (en) | 2003-02-11 |
WO2000061736A9 (en) | 2002-06-13 |
JP2010187679A (ja) | 2010-09-02 |
WO2000061736A2 (en) | 2000-10-19 |
CA2366541A1 (en) | 2000-10-19 |
US6299882B1 (en) | 2001-10-09 |
MXPA01010273A (es) | 2002-09-18 |
EP1171608A2 (en) | 2002-01-16 |
CA2366541C (en) | 2011-11-29 |
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B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
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