BR0009640A - Vìrus de herpes recombinantes e mutantes - Google Patents

Vìrus de herpes recombinantes e mutantes

Info

Publication number
BR0009640A
BR0009640A BR0009640-7A BR0009640A BR0009640A BR 0009640 A BR0009640 A BR 0009640A BR 0009640 A BR0009640 A BR 0009640A BR 0009640 A BR0009640 A BR 0009640A
Authority
BR
Brazil
Prior art keywords
recombinant
herpes viruses
foreign dna
present
mutant herpes
Prior art date
Application number
BR0009640-7A
Other languages
English (en)
Inventor
David E Junker
Original Assignee
Schering Plough Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough Ltd filed Critical Schering Plough Ltd
Publication of BR0009640A publication Critical patent/BR0009640A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Patente de Invenção: "VìRUS DE HERPES RECOMBINANTES E MUTANTES". A presente invenção proporciona métodos e reagentes para induzir imunidade ativa em animais. Em particular, a presente invenção proporciona vírus de herpes recombinantes que apresentam DNA estranho os quais são capazes de induzir imunidade ao vírus de herpes e/ou à fonte do DNA estranho. A presente invenção também proporciona vírus de herpes mutante que apresentam porções de seu genoma suprimidas. Preferencialmente, DNA estranho é introduzido, ou porções do genoma são suprimidas, na estrutura de leitura aberta UL54.5 de um vírus de herpes de aves ou na estrutura de leitura aberta UL43 de vírus da doença de Marek.
BR0009640-7A 1999-04-09 2000-04-07 Vìrus de herpes recombinantes e mutantes BR0009640A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/289,254 US6299882B1 (en) 1999-04-09 1999-04-09 UL54.5 of Marek's disease virus (MDV)
PCT/US2000/009518 WO2000061736A2 (en) 1999-04-09 2000-04-07 Recombinant and mutant marek's disease virus

Publications (1)

Publication Number Publication Date
BR0009640A true BR0009640A (pt) 2002-03-05

Family

ID=23110719

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0009640-7A BR0009640A (pt) 1999-04-09 2000-04-07 Vìrus de herpes recombinantes e mutantes

Country Status (9)

Country Link
US (1) US6299882B1 (pt)
EP (1) EP1171608A2 (pt)
JP (2) JP2002541797A (pt)
AU (1) AU4223900A (pt)
BR (1) BR0009640A (pt)
CA (1) CA2366541C (pt)
MX (1) MXPA01010273A (pt)
WO (1) WO2000061736A2 (pt)
ZA (1) ZA200108263B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6913751B2 (en) 1992-06-12 2005-07-05 Schering-Plough Veterinary Corporation Recombinant avian herpesvirus useful in vaccine production
EP1178111A1 (en) 2000-08-03 2002-02-06 Lohmann Animal Health GmbH & Co. KG Vaccination against host cell-associated herpesviruses
US7314715B2 (en) 2001-06-14 2008-01-01 Schering-Plough Animal Health Corporation Recombinant avian herpesvirus useful in vaccine production
AU2003239589A1 (en) 2002-05-24 2003-12-12 Schering-Plough Ltd. Eta-1 gene and methods for use
CN101135762A (zh) * 2006-09-01 2008-03-05 深圳富泰宏精密工业有限公司 镜头组件及其制造方法
EP2629794B1 (en) * 2010-10-18 2017-06-07 Intervet International B.V. Herpesvirus of turkeys vectored vaccine against avian influenza in poultry
CN103890183A (zh) * 2011-10-21 2014-06-25 英特维特国际股份有限公司 编码传染性喉气管炎病毒和新城疫病毒抗原的重组非致病性马立克氏病病毒构建体
BR112014008161A2 (pt) 2011-10-21 2017-04-11 Intervet Int Bv vírus da doença de marek não patogênico recombinante, método para a preparação do mesmo, molécula do ácido nucleico, célula hospedeira, vacina para aves domésticas, método para a preparação de uma vacina, uso de um vírus da doença de marek não patogênico recombinante, e, método de vacinação de aves domésticas
US9114108B2 (en) 2011-11-30 2015-08-25 Merial, Inc. Recombinant HVT vectors expressing antigens of avian pathogens and uses thereof
ME03433B (me) 2011-11-30 2020-01-20 Merial Inc REKOMBINANTNI VEKTORI GALLID HERPESVIRUSA 3 (MDV SEROTIP 2) KOJI EKSPRIMIRAJU ANTIGENE PTIČJIH PATHOGENA l NJIHOVE UPOTREBE
US9950059B2 (en) * 2014-02-25 2018-04-24 The United States Of America, As Represented By The Secretary Of Agriculture. Immunogenic composition
US11596687B2 (en) 2016-06-17 2023-03-07 Intervet Inc. Recombinant non-pathogenic Marek's disease virus constructs encoding infectious laryngotracheitis virus and infectious bursal disease virus antigens
ES2936117T3 (es) 2016-12-14 2023-03-14 Boehringer Ingelheim Animal Health Usa Inc Vectores recombinantes de VHT que expresan múltiples antígenos de patógenos aviares y vacunas que los comprenden
US11229698B2 (en) 2017-10-12 2022-01-25 Intervet Inc. Recombinant non-pathogenic Marek's Disease virus constructs encoding multiple heterologous antigens
WO2019179966A1 (en) * 2018-03-19 2019-09-26 Boehringer Ingelheim Vetmedica Gmbh Ehv insertion site ul43
WO2020093984A1 (en) * 2018-11-06 2020-05-14 Boehringer Ingelheim Vetmedica Gmbh Immunogenic composition against avian influenza virus h5 subtype
KR20220056241A (ko) 2019-09-11 2022-05-04 조에티스 서비시즈 엘엘씨 조류 병원체의 항원을 발현하는 재조합 칠면조 헤르페스바이러스 벡터 및 이의 용도
MX2022016337A (es) 2020-06-17 2023-04-10 Boehringer Ingelheim Vetmedica Gmbh Vectores de hvt recombinantes que expresan hemaglutinina de influenza y composiciones inmunogenicas, su produccion y usos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965138A (en) * 1985-09-06 1999-10-12 Syntro Corporation Recombinant chimeric virus and uses thereof
CA1319101C (en) 1986-09-03 1993-06-15 Marta Iris Sabara Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules
US5151267A (en) 1988-07-15 1992-09-29 University Of Saskatchewan Bovine herpesvirus type 1 polypeptides and vaccines
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5853733A (en) * 1993-02-26 1998-12-29 Syntro Corporation Recombinant herpesvirus of turkeys and uses thereof

Also Published As

Publication number Publication date
AU4223900A (en) 2000-11-14
WO2000061736A3 (en) 2001-02-01
JP2002541797A (ja) 2002-12-10
ZA200108263B (en) 2003-02-11
WO2000061736A9 (en) 2002-06-13
JP2010187679A (ja) 2010-09-02
WO2000061736A2 (en) 2000-10-19
CA2366541A1 (en) 2000-10-19
US6299882B1 (en) 2001-10-09
MXPA01010273A (es) 2002-09-18
EP1171608A2 (en) 2002-01-16
CA2366541C (en) 2011-11-29

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