BR0008006A - Métodos e composições para uso em aplicações deperfusão - Google Patents

Métodos e composições para uso em aplicações deperfusão

Info

Publication number
BR0008006A
BR0008006A BR0008006-3A BR0008006A BR0008006A BR 0008006 A BR0008006 A BR 0008006A BR 0008006 A BR0008006 A BR 0008006A BR 0008006 A BR0008006 A BR 0008006A
Authority
BR
Brazil
Prior art keywords
compositions
methods
fluid
applications
composition
Prior art date
Application number
BR0008006-3A
Other languages
English (en)
Inventor
Paul E Segall
Harold D Watz
Hal Sternberg
Original Assignee
Biotime Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotime Inc filed Critical Biotime Inc
Publication of BR0008006A publication Critical patent/BR0008006A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/718Starch or degraded starch, e.g. amylose, amylopectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • External Artificial Organs (AREA)

Abstract

Patente de Invenção: "MéTODOS E COMPOSIçõES PARA USOEM APLICAçõES DE PERFUSãO". Métodos e composições parauso em aplicações de perfusão são fornecidos. Nos métodosobjetos, um sujeito ou um derivado deste, por exemplo órgão outecido isolado, é infundido, perfundido e/ou transfundido com pelomenos duas composições fluidas. A primeira composição fluida éuma solução tipo plasma sem tampão biológico de ocorrência nãonatural e a segunda composição fluida é uma composição desangue fluida. Em uma modalidade preferida, um volume adicionalda primeira solução, ou um derivado do mesmo, é administrada aopaciente seguindo a introdução da composição fluida de sangue.São também fornecidos kits e sistemas para execução dosmétodos objetos. Os métodos e composições objetos encontramuso na variedade de aplicações de perfusão, incluíndo otratamento de aplicações cirúrgicas hipotérmicas, procedimentoscriogênicos, e outros.
BR0008006-3A 1999-02-03 2000-01-24 Métodos e composições para uso em aplicações deperfusão BR0008006A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/243,921 US6589223B1 (en) 1999-02-03 1999-02-03 Method and compositions for use in perfusion applications
PCT/US2000/001703 WO2000045873A1 (en) 1999-02-03 2000-01-24 Methods and compositions for use in perfusion applications

Publications (1)

Publication Number Publication Date
BR0008006A true BR0008006A (pt) 2001-12-04

Family

ID=22920663

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008006-3A BR0008006A (pt) 1999-02-03 2000-01-24 Métodos e composições para uso em aplicações deperfusão

Country Status (14)

Country Link
US (3) US6589223B1 (pt)
EP (1) EP1150728A4 (pt)
JP (2) JP2002536078A (pt)
CN (1) CN1200742C (pt)
AR (1) AR022482A1 (pt)
AU (1) AU765144B2 (pt)
BR (1) BR0008006A (pt)
CA (1) CA2362051C (pt)
EA (1) EA003171B1 (pt)
IL (1) IL144710A0 (pt)
MX (1) MXPA01007875A (pt)
TW (1) TW542728B (pt)
WO (1) WO2000045873A1 (pt)
ZA (1) ZA200107243B (pt)

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US8409846B2 (en) 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US6589223B1 (en) * 1999-02-03 2003-07-08 Biotime, Inc. Method and compositions for use in perfusion applications
US6718735B2 (en) * 2002-03-19 2004-04-13 Baxter International Inc. Albumin in a flexible polymeric container
US7354342B2 (en) * 2003-07-30 2008-04-08 Igt Gaming device having a multiple coordinate award distributor including award percentages
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
CA3178010A1 (en) * 2004-10-07 2006-04-20 Transmedics, Inc. Systems and methods for ex-vivo organ care
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9301519B2 (en) * 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
EP1904151A4 (en) * 2005-06-22 2011-06-22 Univ Pittsburgh EMERGENCY RESERVE AND PRESERVATION METHODS
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US8286159B2 (en) * 2005-12-22 2012-10-09 Alan Joshua Shapiro Method and apparatus for gryphing a data storage medium
CA2980782C (en) * 2006-04-19 2020-10-27 Transmedics, Inc. Systems and methods for ex vivo organ care
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
CN101888846B (zh) * 2007-10-05 2013-02-27 国立大学法人千叶大学 稳定的含碳酸氢根离子的药物溶液
US20090123436A1 (en) * 2007-11-08 2009-05-14 Surmodics, Inc. Cryopreservative compositions and methods
US10750738B2 (en) * 2008-01-31 2020-08-25 Transmedics, Inc. Systems and methods for ex vivo lung care
SE534527C2 (sv) * 2009-09-24 2011-09-20 Vivoline Medical Ab Förfarande, anordning och vätska för behandling av ett hjärta efter uttagning
CN103841824B (zh) 2011-04-14 2016-12-14 特兰斯迈迪茨公司 用于供体肺的离体机器灌注的器官护理溶液
US8579880B2 (en) * 2012-03-01 2013-11-12 Outcome Solutions, Llc Devices and methods for making and administering an intravenous liquid with supersaturated dissolved gas
IL303658B2 (en) 2014-06-02 2024-07-01 Transmedics Inc Extracorporeal system for organ treatment
CA2970117A1 (en) 2014-12-12 2016-06-16 Darren FREED Apparatus and method for organ perfusion
ES2853027T3 (es) 2015-09-09 2021-09-14 Transmedics Inc Cánula aórtica para sistema de cuidado de órganos ex vivo
EP3462861B9 (en) 2016-05-30 2023-12-20 Transmedics, Inc. Method for ex vivo lung ventilation with a varying exterior pressure

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Also Published As

Publication number Publication date
US7503913B2 (en) 2009-03-17
TW542728B (en) 2003-07-21
MXPA01007875A (es) 2002-08-20
EA200100855A1 (ru) 2002-02-28
JP5180912B2 (ja) 2013-04-10
IL144710A0 (en) 2002-06-30
WO2000045873A1 (en) 2000-08-10
CA2362051A1 (en) 2000-08-10
AU765144B2 (en) 2003-09-11
JP2009242404A (ja) 2009-10-22
CA2362051C (en) 2010-06-29
CN1200742C (zh) 2005-05-11
EA003171B1 (ru) 2003-02-27
EP1150728A4 (en) 2004-09-29
US6589223B1 (en) 2003-07-08
US6991624B2 (en) 2006-01-31
AR022482A1 (es) 2002-09-04
ZA200107243B (en) 2002-09-02
US20040018966A1 (en) 2004-01-29
US20060088606A1 (en) 2006-04-27
AU3349700A (en) 2000-08-25
CN1346286A (zh) 2002-04-24
JP2002536078A (ja) 2002-10-29
EP1150728A1 (en) 2001-11-07

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10 (VIII), 11, 13 E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.