BR0008006A - Métodos e composições para uso em aplicações deperfusão - Google Patents
Métodos e composições para uso em aplicações deperfusãoInfo
- Publication number
- BR0008006A BR0008006A BR0008006-3A BR0008006A BR0008006A BR 0008006 A BR0008006 A BR 0008006A BR 0008006 A BR0008006 A BR 0008006A BR 0008006 A BR0008006 A BR 0008006A
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- methods
- fluid
- applications
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
- A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Physiology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- External Artificial Organs (AREA)
Abstract
Patente de Invenção: "MéTODOS E COMPOSIçõES PARA USOEM APLICAçõES DE PERFUSãO". Métodos e composições parauso em aplicações de perfusão são fornecidos. Nos métodosobjetos, um sujeito ou um derivado deste, por exemplo órgão outecido isolado, é infundido, perfundido e/ou transfundido com pelomenos duas composições fluidas. A primeira composição fluida éuma solução tipo plasma sem tampão biológico de ocorrência nãonatural e a segunda composição fluida é uma composição desangue fluida. Em uma modalidade preferida, um volume adicionalda primeira solução, ou um derivado do mesmo, é administrada aopaciente seguindo a introdução da composição fluida de sangue.São também fornecidos kits e sistemas para execução dosmétodos objetos. Os métodos e composições objetos encontramuso na variedade de aplicações de perfusão, incluíndo otratamento de aplicações cirúrgicas hipotérmicas, procedimentoscriogênicos, e outros.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/243,921 US6589223B1 (en) | 1999-02-03 | 1999-02-03 | Method and compositions for use in perfusion applications |
PCT/US2000/001703 WO2000045873A1 (en) | 1999-02-03 | 2000-01-24 | Methods and compositions for use in perfusion applications |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0008006A true BR0008006A (pt) | 2001-12-04 |
Family
ID=22920663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0008006-3A BR0008006A (pt) | 1999-02-03 | 2000-01-24 | Métodos e composições para uso em aplicações deperfusão |
Country Status (14)
Country | Link |
---|---|
US (3) | US6589223B1 (pt) |
EP (1) | EP1150728A4 (pt) |
JP (2) | JP2002536078A (pt) |
CN (1) | CN1200742C (pt) |
AR (1) | AR022482A1 (pt) |
AU (1) | AU765144B2 (pt) |
BR (1) | BR0008006A (pt) |
CA (1) | CA2362051C (pt) |
EA (1) | EA003171B1 (pt) |
IL (1) | IL144710A0 (pt) |
MX (1) | MXPA01007875A (pt) |
TW (1) | TW542728B (pt) |
WO (1) | WO2000045873A1 (pt) |
ZA (1) | ZA200107243B (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8409846B2 (en) | 1997-09-23 | 2013-04-02 | The United States Of America As Represented By The Department Of Veteran Affairs | Compositions, methods and devices for maintaining an organ |
US6589223B1 (en) * | 1999-02-03 | 2003-07-08 | Biotime, Inc. | Method and compositions for use in perfusion applications |
US6718735B2 (en) * | 2002-03-19 | 2004-04-13 | Baxter International Inc. | Albumin in a flexible polymeric container |
US7354342B2 (en) * | 2003-07-30 | 2008-04-08 | Igt | Gaming device having a multiple coordinate award distributor including award percentages |
US8304181B2 (en) | 2004-10-07 | 2012-11-06 | Transmedics, Inc. | Method for ex-vivo organ care and for using lactate as an indication of donor organ status |
CA3178010A1 (en) * | 2004-10-07 | 2006-04-20 | Transmedics, Inc. | Systems and methods for ex-vivo organ care |
US12010987B2 (en) | 2004-10-07 | 2024-06-18 | Transmedics, Inc. | Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status |
US9301519B2 (en) * | 2004-10-07 | 2016-04-05 | Transmedics, Inc. | Systems and methods for ex-vivo organ care |
EP1904151A4 (en) * | 2005-06-22 | 2011-06-22 | Univ Pittsburgh | EMERGENCY RESERVE AND PRESERVATION METHODS |
US9078428B2 (en) | 2005-06-28 | 2015-07-14 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
US8286159B2 (en) * | 2005-12-22 | 2012-10-09 | Alan Joshua Shapiro | Method and apparatus for gryphing a data storage medium |
CA2980782C (en) * | 2006-04-19 | 2020-10-27 | Transmedics, Inc. | Systems and methods for ex vivo organ care |
US9457179B2 (en) | 2007-03-20 | 2016-10-04 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
CN101888846B (zh) * | 2007-10-05 | 2013-02-27 | 国立大学法人千叶大学 | 稳定的含碳酸氢根离子的药物溶液 |
US20090123436A1 (en) * | 2007-11-08 | 2009-05-14 | Surmodics, Inc. | Cryopreservative compositions and methods |
US10750738B2 (en) * | 2008-01-31 | 2020-08-25 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
SE534527C2 (sv) * | 2009-09-24 | 2011-09-20 | Vivoline Medical Ab | Förfarande, anordning och vätska för behandling av ett hjärta efter uttagning |
CN103841824B (zh) | 2011-04-14 | 2016-12-14 | 特兰斯迈迪茨公司 | 用于供体肺的离体机器灌注的器官护理溶液 |
US8579880B2 (en) * | 2012-03-01 | 2013-11-12 | Outcome Solutions, Llc | Devices and methods for making and administering an intravenous liquid with supersaturated dissolved gas |
IL303658B2 (en) | 2014-06-02 | 2024-07-01 | Transmedics Inc | Extracorporeal system for organ treatment |
CA2970117A1 (en) | 2014-12-12 | 2016-06-16 | Darren FREED | Apparatus and method for organ perfusion |
ES2853027T3 (es) | 2015-09-09 | 2021-09-14 | Transmedics Inc | Cánula aórtica para sistema de cuidado de órganos ex vivo |
EP3462861B9 (en) | 2016-05-30 | 2023-12-20 | Transmedics, Inc. | Method for ex vivo lung ventilation with a varying exterior pressure |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3677024A (en) | 1970-01-20 | 1972-07-18 | Paul E Segall | Preservation and storage of biologic materials |
US3937821A (en) | 1971-08-21 | 1976-02-10 | Kyorin Seiyaku Kabushiki Kaisha | Plasma substitute including artificial starch and method for the preparation thereof |
US4001401A (en) | 1975-02-02 | 1977-01-04 | Alza Corporation | Blood substitute and blood plasma expander comprising polyhemoglobin |
US4061736A (en) | 1975-02-02 | 1977-12-06 | Alza Corporation | Pharmaceutically acceptable intramolecularly cross-linked, stromal-free hemoglobin |
DE2801123C2 (de) | 1977-01-26 | 1986-01-02 | Armour Pharma GmbH & Co KG, 3440 Eschwege | Verfahren zur Herstellung eines intravenös applizierbaren Serumeiweiß-Präparates |
EP0185759B2 (en) | 1984-06-22 | 2004-06-02 | Btg International Limited | Electrolyte solutions and (in vivo) use thereof |
US5084377A (en) * | 1984-09-19 | 1992-01-28 | Larry Rowan | Cryogenic suspension method |
US4908350A (en) | 1985-10-31 | 1990-03-13 | The Regents Of The University Of California | Hyperosmotic/hyperoncotic solutions for resuscitation of hypodynamic shock |
US5210083A (en) * | 1986-07-17 | 1993-05-11 | Ed. Geistlich Sohne A.G. Fur Chemische Industrie | Pharmaceutical compositions |
JPS6360931A (ja) | 1986-08-29 | 1988-03-17 | Noboru Sato | 血液または血液製剤保存液およびこれを用いた血液または血液製剤の保存方法 |
US4927806A (en) * | 1987-04-23 | 1990-05-22 | The Regents Of The University Of California | Saturated salt/concentrated dextran formulation to treat hemorrhage |
EP0397689B1 (en) * | 1987-12-24 | 1994-05-11 | BORODY, Thomas Julius | Orthostatic lavage solutions |
USRE34077E (en) * | 1988-05-02 | 1992-09-22 | Cryomedical Sciences, Inc. | Blood substitute |
US4923442A (en) * | 1988-05-02 | 1990-05-08 | Cryomedical Sciences Inc. | Blood substitute |
US5130230A (en) * | 1988-05-02 | 1992-07-14 | Cryomedical Sciences, Inc. | Blood substitute |
US5082831A (en) * | 1989-12-05 | 1992-01-21 | Cryovita Laboratories, Inc. | Total body washout solution and method of use |
US5171526A (en) * | 1990-01-05 | 1992-12-15 | Allergan, Inc. | Ophthalmic compositions and methods for preserving and using same |
CA2066374C (en) | 1991-04-19 | 2002-01-29 | Paul E. Segall | Solution for perfusing primates |
WO1993002653A1 (en) * | 1991-08-08 | 1993-02-18 | Segel Leigh D | Fluorocarbon blood substitute |
US5334142A (en) * | 1991-09-09 | 1994-08-02 | New York University | Selective aortic perfusion system |
US5374428A (en) * | 1993-03-23 | 1994-12-20 | Kansas State University Research Foundation | Supplementation of protein diets with di- and tripeptides |
US5407428A (en) * | 1993-06-04 | 1995-04-18 | Biotime, Inc. | Solutions for use as plasma expanders and substitutes |
US5702880A (en) | 1993-06-04 | 1997-12-30 | Biotime, Inc. | Blood substitute comprising 0-5 mM K+ |
US5405742A (en) * | 1993-07-16 | 1995-04-11 | Cyromedical Sciences, Inc. | Solutions for tissue preservation and bloodless surgery and methods using same |
US6218099B1 (en) * | 1994-06-03 | 2001-04-17 | Biotime, Inc. | Methods and compositions for use in perfusion applications |
US5730720A (en) | 1995-08-18 | 1998-03-24 | Ip Scientific, Inc. | Perfusion hyperthermia treatment system and method |
US6589223B1 (en) * | 1999-02-03 | 2003-07-08 | Biotime, Inc. | Method and compositions for use in perfusion applications |
-
1999
- 1999-02-03 US US09/243,921 patent/US6589223B1/en not_active Expired - Lifetime
-
2000
- 2000-01-24 EA EA200100855A patent/EA003171B1/ru not_active IP Right Cessation
- 2000-01-24 CN CNB008060290A patent/CN1200742C/zh not_active Expired - Fee Related
- 2000-01-24 JP JP2000596992A patent/JP2002536078A/ja active Pending
- 2000-01-24 AU AU33497/00A patent/AU765144B2/en not_active Ceased
- 2000-01-24 EP EP00911630A patent/EP1150728A4/en not_active Withdrawn
- 2000-01-24 BR BR0008006-3A patent/BR0008006A/pt not_active Application Discontinuation
- 2000-01-24 IL IL14471000A patent/IL144710A0/xx not_active IP Right Cessation
- 2000-01-24 CA CA2362051A patent/CA2362051C/en not_active Expired - Fee Related
- 2000-01-24 MX MXPA01007875A patent/MXPA01007875A/es not_active Application Discontinuation
- 2000-01-24 WO PCT/US2000/001703 patent/WO2000045873A1/en active IP Right Grant
- 2000-02-02 AR ARP000100449A patent/AR022482A1/es not_active Application Discontinuation
- 2000-02-03 TW TW089102018A patent/TW542728B/zh not_active IP Right Cessation
-
2001
- 2001-08-31 ZA ZA200107243A patent/ZA200107243B/en unknown
-
2003
- 2003-05-23 US US10/445,392 patent/US6991624B2/en not_active Expired - Lifetime
-
2005
- 2005-10-12 US US11/249,757 patent/US7503913B2/en not_active Expired - Fee Related
-
2009
- 2009-06-02 JP JP2009133059A patent/JP5180912B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7503913B2 (en) | 2009-03-17 |
TW542728B (en) | 2003-07-21 |
MXPA01007875A (es) | 2002-08-20 |
EA200100855A1 (ru) | 2002-02-28 |
JP5180912B2 (ja) | 2013-04-10 |
IL144710A0 (en) | 2002-06-30 |
WO2000045873A1 (en) | 2000-08-10 |
CA2362051A1 (en) | 2000-08-10 |
AU765144B2 (en) | 2003-09-11 |
JP2009242404A (ja) | 2009-10-22 |
CA2362051C (en) | 2010-06-29 |
CN1200742C (zh) | 2005-05-11 |
EA003171B1 (ru) | 2003-02-27 |
EP1150728A4 (en) | 2004-09-29 |
US6589223B1 (en) | 2003-07-08 |
US6991624B2 (en) | 2006-01-31 |
AR022482A1 (es) | 2002-09-04 |
ZA200107243B (en) | 2002-09-02 |
US20040018966A1 (en) | 2004-01-29 |
US20060088606A1 (en) | 2006-04-27 |
AU3349700A (en) | 2000-08-25 |
CN1346286A (zh) | 2002-04-24 |
JP2002536078A (ja) | 2002-10-29 |
EP1150728A1 (en) | 2001-11-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0008006A (pt) | Métodos e composições para uso em aplicações deperfusão | |
Goodnough et al. | Bloodless medicine: clinical care without allogeneic blood transfusion. | |
ATE375809T1 (de) | Zugangsöffnung mit klip und verwendungsverfahren | |
BR0104817A (pt) | Sistema de liberação transdérmica de drogas baseado em solução | |
BR9811825A (pt) | Uso de lactobacillus para redução do nìvel de fibrinogênio no sangue | |
BR9810745A (pt) | Derivados de benzimidazol | |
Sheldon et al. | Cutaneous mucormycosis: two documented cases of suspected nosocomial cause | |
Sejourne et al. | Effect of haemodilution on transfusion requirements in liver resection | |
BRPI0408439A (pt) | composição farmacêutica lìquida aquosa, método para preparar e uso da mesma, método para tratar uma sìndrome responsiva ao fator vii, e, recipiente hermético | |
BR0110049A (pt) | Agonista de cxcr4, uso de um agonista de cxcr4, e composição farmacêutica | |
KR940003564A (ko) | 특정 질환의 예방 및 치료용 약제를 제조하기 위한 c1- 불활성제화제의 용도 | |
TW200501932A (en) | Sterile combined preparation and manufacture method thereof | |
Sealy | Hypothermia: its possible role in cardiac surgery | |
De Falco et al. | Intra-operative local plus systemic tranexamic acid significantly decreases post-operative bleeding and the need for allogeneic blood transfusion in total knee arthroplasty | |
KR960013383A (ko) | 항혈전성 및 피브린용해성 치료제와 조합하여 사용되는 치료제로서의 폰 빌레브란트 인자(vWF)-함유 농축물의 용도 | |
BRPI0410374A (pt) | composição farmacêutica que compreende valsartano | |
HUP0401188A2 (hu) | Hiperelágazásos amilopektin sebészeti, gyógyító vagy diagnosztikai eljárásokban emlősöknél való alkalmazásra, különösen plazmatérfogat-növelőként | |
Østergaard et al. | Intra-articular corticosteroids in arthritic disease: a guide to treatment | |
BRPI0416461A (pt) | método para o tratamento de episódios de sangramento, formulação farmacêutica, e, uso de um polipeptìdeo fxi | |
Galois et al. | Autologous bone marrow graft and treatment of delayed and non-unions of long bones: technical aspects | |
CN106822090B (zh) | 3,4,7-三羟基异黄酮或3-甲氧基大豆素在制备抑制血小板聚集和血栓药物中的应用 | |
SATTERLEE et al. | The use of herudin in the transfusion of blood | |
JP4752058B2 (ja) | 肝再生用骨髄細胞画分 | |
Wang et al. | Effectiveness and safeties of hemocoagulase and tranexamic acid to reduce perioperative blood loss in intertrochanteric fracture PFNA fixation | |
BRPI0413032A (pt) | diamidas de aminoacidos em uma posição não-(alfa), úteis como adjuvantes na administração de agentes biológicos ativos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10 (VIII), 11, 13 E 25 DA LPI. |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |