BG45047A3 - - Google Patents

Info

Publication number
BG45047A3
BG45047A3 BG8674576A BG7457686A BG45047A3 BG 45047 A3 BG45047 A3 BG 45047A3 BG 8674576 A BG8674576 A BG 8674576A BG 7457686 A BG7457686 A BG 7457686A BG 45047 A3 BG45047 A3 BG 45047A3
Authority
BG
Bulgaria
Application number
BG8674576A
Inventor
Thomas D Ingolia
Stephen W Queener
Suellen M Samson
Paul L Skatrud
Original Assignee
Lilly And Co, Eli,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US72587085A priority Critical
Priority to US79938485A priority
Application filed by Lilly And Co, Eli,Us filed Critical Lilly And Co, Eli,Us
Publication of BG45047A3 publication Critical patent/BG45047A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • C12N15/69Increasing the copy number of the vector
BG8674576A 1985-04-22 1986-04-18 BG45047A3 (xx)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US72587085A true 1985-04-22 1985-04-22
US79938485A true 1985-11-18 1985-11-18

Publications (1)

Publication Number Publication Date
BG45047A3 true BG45047A3 (xx) 1989-03-15

Family

ID=27111238

Family Applications (2)

Application Number Title Priority Date Filing Date
BG8674576A BG45047A3 (xx) 1985-04-22 1986-04-18
BG8778442A BG45219A3 (xx) 1985-04-22 1986-04-18

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG8778442A BG45219A3 (xx) 1985-04-22 1986-04-18

Country Status (14)

Country Link
EP (1) EP0200425B1 (xx)
JP (1) JPH0787788B2 (xx)
KR (1) KR860008287A (xx)
CN (1) CN86102604A (xx)
AU (2) AU592791B2 (xx)
BG (2) BG45047A3 (xx)
CA (1) CA1309673C (xx)
DE (1) DE3683080D1 (xx)
DK (1) DK178386A (xx)
ES (3) ES8800344A1 (xx)
FI (1) FI95810C (xx)
HU (1) HU202279B (xx)
IE (1) IE58780B1 (xx)
IL (1) IL78531D0 (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI88175C (fi) 1980-04-03 1993-04-13 Biogen Inc Rekombinant-dna-molekyler och foerfaranden foer framstaellning av polypeptider liknande humant -interferon
GB8508800D0 (en) * 1985-04-04 1985-05-09 Glaxo Group Ltd Microbiological process
US4892819A (en) * 1985-11-25 1990-01-09 Eli Lilly And Company Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum
DE3789880T2 (de) * 1986-01-31 1994-09-08 Beecham Group Plc Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen.
CA1327170C (en) * 1987-03-04 1994-02-22 Stephen Wyatt Queener Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase and deacetylcephalosporin c synthetase
GB2208077A (en) * 1987-04-24 1989-02-22 Antibioticos Sa Isopenicillin n synthetase gene derived from aspergillus nidulans
AU1975988A (en) * 1987-08-10 1989-02-16 Governers Of The University Of Alberta, The Cloning and nucleotide sequence determination of the isopenicillin n. synthetase gene from streptomyces clauvigerus
US4885252A (en) * 1987-09-08 1989-12-05 Eli Lilly And Company Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from aspergillus nidulans
US4950603A (en) * 1987-11-02 1990-08-21 Eli Lilly And Company Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from Streptomyces lipmanii
GB8728811D0 (en) * 1987-12-09 1988-01-27 Beecham Group Plc Novel substance
US6258555B1 (en) 1987-12-09 2001-07-10 Beecham Group P.L.C. DNA encoding ACV synthetase
KR0171897B1 (ko) * 1989-12-27 1999-02-01 후지사와 도모끼찌로 7-아미노세펨 화합물 또는 그 염류의 제조 방법
EP0437378B1 (en) * 1990-01-12 1999-05-19 Glaxo Group Limited DNA sequence for an antibiotic biosynthesis enzyme
WO1996010084A1 (en) * 1994-09-28 1996-04-04 Novo Nordisk A/S Process for the production of secondary metabolites
DE19755302A1 (de) * 1997-12-12 1999-06-17 Hoechst Marion Roussel De Gmbh Neuer Transkriptionsfaktor CPCR1 zur Regulation des Isopenicillin N-Synthetase-Gens (pcbC) und des AC-/ACV-Synthetase-Gens (pcbAB)
CA2361848A1 (en) 1999-04-02 2000-10-12 Dupont Pharmaceuticals Company Novel lactam inhibitors of matrix metalloproteinases, tnf-.alpha., and aggrecanase

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3330003A1 (de) * 1982-10-21 1984-10-31 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig Dna-sequenz und dna-strukturen und sie verwendendes verfahren zur herstellung von penicillin-acylase
CA1278540C (en) * 1983-07-22 1991-01-02 Eli Lilly And Company Modified antibiotic resistance gene
US4762786A (en) * 1984-09-27 1988-08-09 Eli Lilly And Company Vectors and conditions which allow genetic transformation of cephalosporium
GB8508800D0 (en) * 1985-04-04 1985-05-09 Glaxo Group Ltd Microbiological process
US4892819A (en) * 1985-11-25 1990-01-09 Eli Lilly And Company Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum

Also Published As

Publication number Publication date
ES8800344A1 (es) 1987-11-01
ES8802585A1 (es) 1988-08-16
AU619596B2 (en) 1992-01-30
CN86102604A (zh) 1986-11-26
AU592791B2 (en) 1990-01-25
EP0200425B1 (en) 1991-12-27
EP0200425A3 (en) 1988-07-06
AU5643186A (en) 1986-10-30
FI95810B (fi) 1995-12-15
FI861653A (fi) 1986-10-23
IE861029L (en) 1986-10-22
ES8900142A1 (es) 1989-01-16
HUT40705A (en) 1987-01-28
ES557829A0 (es) 1989-01-16
FI861653A0 (fi) 1986-04-18
ES554218A0 (es) 1987-11-01
JPS61254192A (en) 1986-11-11
KR860008287A (ko) 1986-11-14
ES557658A0 (es) 1988-08-16
EP0200425A2 (en) 1986-11-05
JPH0787788B2 (ja) 1995-09-27
IL78531D0 (en) 1986-08-31
FI95810C (fi) 1996-03-25
DE3683080D1 (de) 1992-02-06
AU4234789A (en) 1990-01-11
CA1309673C (en) 1992-11-03
DK178386D0 (da) 1986-04-18
DK178386A (da) 1986-10-23
IE58780B1 (en) 1993-11-17
BG45219A3 (xx) 1989-04-14
HU202279B (en) 1991-02-28

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