BG28417A3 - Метод за получаване на транс-5а-арил-декахидробензазепини - Google Patents

Метод за получаване на транс-5а-арил-декахидробензазепини

Info

Publication number
BG28417A3
BG28417A3 BG037703A BG3770377A BG28417A3 BG 28417 A3 BG28417 A3 BG 28417A3 BG 037703 A BG037703 A BG 037703A BG 3770377 A BG3770377 A BG 3770377A BG 28417 A3 BG28417 A3 BG 28417A3
Authority
BG
Bulgaria
Prior art keywords
trans
aryldecahydrobenzazepine
obtaining
decahydrobenzepines
proved
Prior art date
Application number
BG037703A
Other languages
English (en)
Inventor
Dennis Zimmermann
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BG28417A3 publication Critical patent/BG28417A3/bg

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Метод за получаване на охарактеризирани и доказани в описанието транс-5а-арил-декахидробензепини с формула... Патентните претенции са формулирани в 5 точки.
BG037703A 1976-11-02 1977-11-01 Метод за получаване на транс-5а-арил-декахидробензазепини BG28417A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/737,959 US4141894A (en) 1976-11-02 1976-11-02 Trans-5a-aryl-decahydrobenzazepines

Publications (1)

Publication Number Publication Date
BG28417A3 true BG28417A3 (bg) 1980-04-15

Family

ID=24965985

Family Applications (1)

Application Number Title Priority Date Filing Date
BG037703A BG28417A3 (bg) 1976-11-02 1977-11-01 Метод за получаване на транс-5а-арил-декахидробензазепини

Country Status (26)

Country Link
US (1) US4141894A (bg)
JP (1) JPS5356683A (bg)
AR (1) AR221835A1 (bg)
AT (1) AT358046B (bg)
AU (1) AU510911B2 (bg)
BE (1) BE860315A (bg)
BG (1) BG28417A3 (bg)
CA (2) CA1096861A (bg)
DD (1) DD133797A5 (bg)
DE (1) DE2748468A1 (bg)
DK (1) DK485177A (bg)
ES (1) ES463782A1 (bg)
FR (1) FR2369268A1 (bg)
GB (1) GB1585296A (bg)
GR (1) GR70052B (bg)
IE (1) IE45899B1 (bg)
IL (1) IL53235A0 (bg)
NL (1) NL7712052A (bg)
PH (1) PH13506A (bg)
PL (1) PL108916B1 (bg)
PT (1) PT67195B (bg)
RO (1) RO72899B (bg)
SE (1) SE7712219L (bg)
SU (1) SU843743A3 (bg)
YU (1) YU257577A (bg)
ZA (1) ZA776498B (bg)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2703697C (en) * 2000-07-06 2012-09-04 Daiichi Sankyo Company, Limited Acid addition salts of hydropyridine derivatives
FR3062850B1 (fr) * 2017-02-10 2020-01-31 Guerbet Procede de preparation monotope de composes organo-iodes
FR3084668A1 (fr) 2018-08-02 2020-02-07 Guerbet Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA734895B (en) * 1972-07-20 1974-06-26 Du Pont Analgesigs and/or narcotic antagonists
US4001248A (en) * 1974-06-07 1977-01-04 Eli Lilly And Company N-cycloalkylmethyl decahydroisoquinolines
US4001247A (en) * 1974-06-07 1977-01-04 Eli Lilly And Company 1-ethyl 3a-(substituted-phenyl) decahydroisoquinoline

Also Published As

Publication number Publication date
PH13506A (en) 1980-06-03
AT358046B (de) 1980-08-11
DK485177A (da) 1978-05-03
AU3023377A (en) 1979-05-10
PL108916B1 (en) 1980-05-31
FR2369268B1 (bg) 1980-05-16
IE45899L (en) 1978-05-02
ZA776498B (en) 1979-06-27
SU843743A3 (ru) 1981-06-30
IE45899B1 (en) 1982-12-29
AR221835A1 (es) 1981-03-31
SE7712219L (sv) 1978-05-03
CA1096861A (en) 1981-03-03
RO72899B (ro) 1981-03-22
ATA782277A (de) 1980-01-15
DD133797A5 (de) 1979-01-24
PL201883A1 (pl) 1979-01-29
FR2369268A1 (fr) 1978-05-26
ES463782A1 (es) 1978-12-16
GB1585296A (en) 1981-02-25
JPS5356683A (en) 1978-05-23
IL53235A0 (en) 1977-12-30
PT67195A (en) 1977-11-01
AU510911B2 (en) 1980-07-17
NL7712052A (nl) 1978-05-05
US4141894A (en) 1979-02-27
BE860315A (fr) 1978-04-28
DE2748468A1 (de) 1978-05-03
CA1102319A (en) 1981-06-02
YU257577A (en) 1983-01-21
PT67195B (en) 1979-03-23
GR70052B (bg) 1982-07-26

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