BG106361A - Лиганди на нуклеинови киселини за тенасцин - с - Google Patents

Лиганди на нуклеинови киселини за тенасцин - с Download PDF

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Publication number
BG106361A
BG106361A BG106361A BG10636102A BG106361A BG 106361 A BG106361 A BG 106361A BG 106361 A BG106361 A BG 106361A BG 10636102 A BG10636102 A BG 10636102A BG 106361 A BG106361 A BG 106361A
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BG
Bulgaria
Prior art keywords
tenascin
nucleic acid
nucleic acids
complex
candidate mixture
Prior art date
Application number
BG106361A
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Bulgarian (bg)
English (en)
Inventor
Brian Hicke
Stephen Warren
David Parma
Larry Gold
Original Assignee
Gilead Sciences, Inc.
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Publication date
Application filed by Gilead Sciences, Inc. filed Critical Gilead Sciences, Inc.
Publication of BG106361A publication Critical patent/BG106361A/bg

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
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    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
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    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
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    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96455—Kallikrein (3.4.21.34; 3.4.21.35)
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    • G01—MEASURING; TESTING
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    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
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    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/972—Plasminogen activators
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    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/976—Trypsin; Chymotrypsin

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BG106361A 1999-07-29 2002-01-29 Лиганди на нуклеинови киселини за тенасцин - с BG106361A (bg)

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US09/364,902 US6232071B1 (en) 1990-06-11 1999-07-29 Tenascin-C nucleic acid ligands
PCT/US2000/002167 WO2001009390A1 (en) 1999-07-29 2000-01-28 Tenascin-c nucleic acid ligands

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