BG106001A - Метод за лечение на апнея по време на сън - Google Patents

Метод за лечение на апнея по време на сън

Info

Publication number
BG106001A
BG106001A BG106001A BG10600101A BG106001A BG 106001 A BG106001 A BG 106001A BG 106001 A BG106001 A BG 106001A BG 10600101 A BG10600101 A BG 10600101A BG 106001 A BG106001 A BG 106001A
Authority
BG
Bulgaria
Prior art keywords
sleep apnoea
treating sleep
chlorphenyl
snoring
racemates
Prior art date
Application number
BG106001A
Other languages
English (en)
Inventor
Sharon Cheetham
David Heal
Carl Mendel
Timothy SEATON
Steve Weinstein
Anton Safer
Original Assignee
Abbott Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co. Kg filed Critical Abbott Gmbh & Co. Kg
Publication of BG106001A publication Critical patent/BG106001A/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Harvester Elements (AREA)
  • Fluid-Pressure Circuits (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Изобретението се отнася до съединение или до негови фармацевтично приемливи соли с формула, в коятоR1 и R2 са независимо един от друг Н или метил, до негови отделни енантиомери или рацемати, например N,N-диметил-1- [1-(4-хлорофенил) циклобутил]-3-метилбутиламин хидрохлорид, в даден случай под формата на неговия монохидрат, както и до лечение на разстройства на съня - апнея по време на сън и хъркане.
BG106001A 1999-03-19 2001-10-10 Метод за лечение на апнея по време на сън BG106001A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12518599P 1999-03-19 1999-03-19
PCT/US2000/007177 WO2000056314A1 (en) 1999-03-19 2000-03-17 Method of treating sleep apnoea

Publications (1)

Publication Number Publication Date
BG106001A true BG106001A (bg) 2002-06-28

Family

ID=22418567

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106001A BG106001A (bg) 1999-03-19 2001-10-10 Метод за лечение на апнея по време на сън

Country Status (26)

Country Link
US (1) US6365631B1 (bg)
EP (1) EP1169029B1 (bg)
JP (1) JP2003521469A (bg)
KR (1) KR100682291B1 (bg)
CN (1) CN1161114C (bg)
AT (1) ATE294573T1 (bg)
AU (1) AU773489B2 (bg)
BG (1) BG106001A (bg)
BR (1) BR0009080A (bg)
CA (1) CA2367022A1 (bg)
CZ (1) CZ298293B6 (bg)
DE (1) DE60019914T2 (bg)
DK (1) DK1169029T3 (bg)
ES (1) ES2244420T3 (bg)
HK (1) HK1044462B (bg)
HU (1) HUP0200501A3 (bg)
IL (2) IL145244A (bg)
MX (1) MXPA01009464A (bg)
NO (1) NO20014475L (bg)
NZ (1) NZ514014A (bg)
PL (1) PL359467A1 (bg)
PT (1) PT1169029E (bg)
SI (1) SI1169029T1 (bg)
SK (1) SK285308B6 (bg)
WO (1) WO2000056314A1 (bg)
ZA (1) ZA200107678B (bg)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476078B2 (en) 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6974838B2 (en) 1998-08-24 2005-12-13 Sepracor Inc. Methods of treating or preventing pain using sibutramine metabolites
US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
WO2002083631A1 (en) 2001-04-13 2002-10-24 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
EP1545484A4 (en) * 2002-10-05 2010-01-13 Hanmi Pharm Ind Co Ltd PHARMACEUTICAL COMPOSITION COMPRISING CRYSTALLINE SIBUTRAMINE METHANESULFONATE HEMIHYDRATE
US20050131074A1 (en) * 2003-08-04 2005-06-16 Beckman Kristen M. Methods for treating metabolic syndrome
US20050228052A1 (en) * 2004-01-29 2005-10-13 Barberich Timothy J Methods of treating, preventing and managing a sleep disorder using (S)-didesmethylsibutramine
DK1742624T3 (da) 2004-02-18 2010-03-08 Sepracor Inc Dopamin-agonist-kombinationsterapi med sedativer til forbedring af søvnkvalitet
KR100627687B1 (ko) * 2005-04-20 2006-09-25 주식회사 씨티씨바이오 시부트라민 유리염기 함유 조성물 및 이의 제조방법
AU2007322477A1 (en) * 2006-11-22 2008-05-29 Sk Chemicals Co., Ltd. Inclusion complex of sibutramine and beta-cyclodextrin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8531071D0 (en) * 1985-12-17 1986-01-29 Boots Co Plc Therapeutic compound
IE61928B1 (en) * 1988-11-29 1994-11-30 Boots Co Plc Treatment of obesity
US5356934A (en) * 1990-03-29 1994-10-18 Eli Lilly And Company Selected serotonin subtype receptor agonist to treat sleep apnea
US5459164A (en) * 1994-02-03 1995-10-17 Boots Pharmaceuticals, Inc. Medical treatment

Also Published As

Publication number Publication date
CN1356897A (zh) 2002-07-03
WO2000056314A1 (en) 2000-09-28
NO20014475D0 (no) 2001-09-14
IL145244A0 (en) 2002-06-30
CA2367022A1 (en) 2000-09-28
BR0009080A (pt) 2002-02-13
ES2244420T3 (es) 2005-12-16
US6365631B1 (en) 2002-04-02
KR100682291B1 (ko) 2007-02-15
ATE294573T1 (de) 2005-05-15
NO20014475L (no) 2001-11-14
SK285308B6 (sk) 2006-10-05
HK1044462B (zh) 2006-03-03
HK1044462A1 (en) 2002-10-25
JP2003521469A (ja) 2003-07-15
MXPA01009464A (es) 2004-03-19
AU3896800A (en) 2000-10-09
DE60019914D1 (de) 2005-06-09
EP1169029A4 (en) 2004-01-21
DK1169029T3 (da) 2005-08-29
NZ514014A (en) 2004-02-27
CN1161114C (zh) 2004-08-11
PL359467A1 (en) 2004-08-23
CZ20013280A3 (cs) 2002-07-17
DE60019914T2 (de) 2006-05-04
EP1169029A1 (en) 2002-01-09
CZ298293B6 (cs) 2007-08-15
HUP0200501A3 (en) 2004-03-29
SI1169029T1 (sl) 2005-12-31
KR20010113847A (ko) 2001-12-28
PT1169029E (pt) 2005-08-31
AU773489B2 (en) 2004-05-27
IL177626A0 (en) 2006-12-31
ZA200107678B (en) 2003-06-18
EP1169029B1 (en) 2005-05-04
HUP0200501A2 (en) 2002-08-28
SK13382001A3 (sk) 2002-04-04
IL145244A (en) 2006-12-10

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