BG105572A - Treatment of tumors by administration of growth hormone releasing compounds and their antagonists - Google Patents
Treatment of tumors by administration of growth hormone releasing compounds and their antagonistsInfo
- Publication number
- BG105572A BG105572A BG105572A BG10557201A BG105572A BG 105572 A BG105572 A BG 105572A BG 105572 A BG105572 A BG 105572A BG 10557201 A BG10557201 A BG 10557201A BG 105572 A BG105572 A BG 105572A
- Authority
- BG
- Bulgaria
- Prior art keywords
- tumors
- growth hormone
- hormone releasing
- antagonists
- administration
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 102000018997 Growth Hormone Human genes 0.000 title abstract 2
- 108010051696 Growth Hormone Proteins 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title abstract 2
- 239000000122 growth hormone Substances 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- CZCIKBSVHDNIDH-UHFFFAOYSA-N Nalpha-methyl-DL-tryptophan Natural products C1=CC=C2C(CC(NC)C(O)=O)=CNC2=C1 CZCIKBSVHDNIDH-UHFFFAOYSA-N 0.000 abstract 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 abstract 1
- 208000024770 Thyroid neoplasm Diseases 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 208000037841 lung tumor Diseases 0.000 abstract 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 210000001685 thyroid gland Anatomy 0.000 abstract 1
- 208000013076 thyroid tumor Diseases 0.000 abstract 1
- 231100000588 tumorigenic Toxicity 0.000 abstract 1
- 230000000381 tumorigenic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/192,406 US6124263A (en) | 1998-11-16 | 1998-11-16 | Treatment of tumors by administration of growth hormone releasing compounds and their antagonists |
| PCT/EP1999/008662 WO2000029011A1 (en) | 1998-11-16 | 1999-11-11 | Treatment of tumors by administration of growth hormone releasing compounds and their antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG105572A true BG105572A (en) | 2002-01-31 |
Family
ID=22709509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG105572A BG105572A (en) | 1998-11-16 | 2001-06-07 | Treatment of tumors by administration of growth hormone releasing compounds and their antagonists |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US6124263A (hu) |
| EP (1) | EP1131083B1 (hu) |
| JP (1) | JP2002529512A (hu) |
| KR (1) | KR100704138B1 (hu) |
| CN (3) | CN100368014C (hu) |
| AR (1) | AR021286A1 (hu) |
| AT (1) | ATE258062T1 (hu) |
| BG (1) | BG105572A (hu) |
| BR (1) | BR9915390A (hu) |
| CA (1) | CA2350914A1 (hu) |
| CO (1) | CO5140111A1 (hu) |
| CZ (1) | CZ20011577A3 (hu) |
| DE (1) | DE69914365T2 (hu) |
| DK (1) | DK1131083T3 (hu) |
| ES (1) | ES2212650T3 (hu) |
| HK (1) | HK1040934A1 (hu) |
| HU (1) | HUP0104374A3 (hu) |
| IL (1) | IL142858A0 (hu) |
| MX (1) | MXPA01004689A (hu) |
| NO (1) | NO20012367L (hu) |
| NZ (1) | NZ511280A (hu) |
| PL (1) | PL347659A1 (hu) |
| PT (1) | PT1131083E (hu) |
| RU (1) | RU2240133C2 (hu) |
| SK (1) | SK6352001A3 (hu) |
| TR (1) | TR200101350T2 (hu) |
| TW (2) | TWI237565B (hu) |
| UA (1) | UA73100C2 (hu) |
| WO (1) | WO2000029011A1 (hu) |
| ZA (1) | ZA200103182B (hu) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6211156B1 (en) * | 1999-11-10 | 2001-04-03 | Asta Medica A.G. | Peptides for treatment of erectile dysfunction |
| CU23157A1 (es) * | 2001-01-03 | 2006-07-18 | Ct Ingenieria Genetica Biotech | COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL |
| DE10112882A1 (de) * | 2001-03-15 | 2002-09-19 | Max Delbrueck Centrum | Verwendung von Tryptophan-Derivaten zur spezifischen zytostatischen Behandlung von Serotonin-produzierenden Tumoren |
| EP1385879A4 (en) * | 2001-05-10 | 2005-02-02 | Univ Queensland | DIAGNOSIS AND THERAPY OF CANCER OF REPRODUCTIVE ORGANS |
| EP1312363A1 (en) * | 2001-09-28 | 2003-05-21 | Pfizer Products Inc. | Methods of treatment and kits comprising a growth hormone secretagogue |
| TWI331922B (en) * | 2002-08-09 | 2010-10-21 | Ipsen Pharma Sas | Growth hormone releasing peptides |
| WO2005027913A1 (en) * | 2003-09-19 | 2005-03-31 | Pfizer Products Inc. | Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a growth hormone secretagogue |
| US20050164952A1 (en) * | 2004-01-23 | 2005-07-28 | Vital Pharmaceuticals, Inc. | Delivery system for growth hormone releasing peptides |
| US8536120B2 (en) * | 2006-04-28 | 2013-09-17 | The Administrators Of The Tulane Educational Fund | Ghrelin/growth hormone releasing peptide/growth hormone secretatogue receptor antagonists and uses thereof |
| US8299022B2 (en) | 2006-09-27 | 2012-10-30 | Ipsen Pharma S.A.S. | Analogs of ghrelin substituted at the N-terminal |
| WO2008100448A2 (en) | 2007-02-13 | 2008-08-21 | Helsinn Therapeutics (U.S.), Inc. | Method of treating cell proliferative disorders using growth hormone secretagogues |
| US8841257B2 (en) * | 2009-04-10 | 2014-09-23 | Board Of Regents, The University Of Texas System | Inhibitors of STAT3 and uses thereof |
| US9724381B2 (en) | 2009-05-12 | 2017-08-08 | The Administrators Of The Tulane Educational Fund | Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof |
| IT1399610B1 (it) * | 2010-01-28 | 2013-04-26 | Univ Milano Bicocca | Uso di agonisti e antagonisti dei recettori per i growth hormone secretagogues per la prevenzione e il trattamento di convulsioni ed epilessia |
| AU2020218272A1 (en) | 2019-02-08 | 2021-09-02 | United States Government As Represented By The Department Of Veterans Affairs | Growth hormone-releasing hormone antagonists and uses thereof |
| CA3143758A1 (en) * | 2019-07-18 | 2021-01-21 | University Of Miami | Ghrh antagonists for use in a method of treating sarcoidosis |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2053250A1 (en) * | 1989-04-26 | 1990-10-27 | David H. Coy | Linear somatostatin analogs |
| IT1240643B (it) * | 1990-05-11 | 1993-12-17 | Mediolanum Farmaceutici Spa | Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano |
| US5385682A (en) * | 1990-05-15 | 1995-01-31 | Exxon Research & Engineering Co. | Grease composition |
| ATE284413T1 (de) * | 1993-08-09 | 2004-12-15 | Sod Conseils Rech Applic | Therapeutische peptid derivate |
| US5550212A (en) * | 1993-12-17 | 1996-08-27 | The Administrators Of The Tulane Educational Fund | Analogues of hGH-RH(1-29)NH2 having antagonistic activity |
| US5807985A (en) * | 1996-06-11 | 1998-09-15 | Deghenghi; Romano | Oligopeptide compounds containing D-2-alkyltryptophan capable of promoting the release of growth hormone |
| US6063796A (en) * | 1997-04-04 | 2000-05-16 | Merck & Co., Inc. | Somatostatin agonists |
-
1998
- 1998-11-16 US US09/192,406 patent/US6124263A/en not_active Expired - Fee Related
-
1999
- 1999-10-28 CO CO99068206A patent/CO5140111A1/es unknown
- 1999-11-11 CN CNB2006100998244A patent/CN100368014C/zh not_active Expired - Fee Related
- 1999-11-11 SK SK635-2001A patent/SK6352001A3/sk unknown
- 1999-11-11 PT PT99955974T patent/PT1131083E/pt unknown
- 1999-11-11 CZ CZ20011577A patent/CZ20011577A3/cs unknown
- 1999-11-11 PL PL99347659A patent/PL347659A1/xx unknown
- 1999-11-11 MX MXPA01004689A patent/MXPA01004689A/es not_active IP Right Cessation
- 1999-11-11 TR TR2001/01350T patent/TR200101350T2/xx unknown
- 1999-11-11 AT AT99955974T patent/ATE258062T1/de not_active IP Right Cessation
- 1999-11-11 RU RU2001116722/14A patent/RU2240133C2/ru not_active IP Right Cessation
- 1999-11-11 CN CNB200410045995XA patent/CN1277840C/zh not_active Expired - Fee Related
- 1999-11-11 CA CA002350914A patent/CA2350914A1/en not_active Abandoned
- 1999-11-11 CN CNB998133612A patent/CN1200726C/zh not_active Expired - Fee Related
- 1999-11-11 UA UA2001064044A patent/UA73100C2/uk unknown
- 1999-11-11 JP JP2000582057A patent/JP2002529512A/ja active Pending
- 1999-11-11 EP EP99955974A patent/EP1131083B1/en not_active Expired - Lifetime
- 1999-11-11 WO PCT/EP1999/008662 patent/WO2000029011A1/en active IP Right Grant
- 1999-11-11 BR BR9915390-4A patent/BR9915390A/pt not_active IP Right Cessation
- 1999-11-11 ES ES99955974T patent/ES2212650T3/es not_active Expired - Lifetime
- 1999-11-11 NZ NZ511280A patent/NZ511280A/xx unknown
- 1999-11-11 HU HU0104374A patent/HUP0104374A3/hu unknown
- 1999-11-11 DE DE69914365T patent/DE69914365T2/de not_active Expired - Fee Related
- 1999-11-11 KR KR1020017006163A patent/KR100704138B1/ko not_active IP Right Cessation
- 1999-11-11 DK DK99955974T patent/DK1131083T3/da active
- 1999-11-11 IL IL14285899A patent/IL142858A0/xx unknown
- 1999-11-16 AR ARP990105814A patent/AR021286A1/es unknown
- 1999-11-30 TW TW088117984A patent/TWI237565B/zh not_active IP Right Cessation
- 1999-11-30 TW TW094111886A patent/TWI263642B/zh not_active IP Right Cessation
-
2001
- 2001-04-19 ZA ZA200103182A patent/ZA200103182B/en unknown
- 2001-05-14 NO NO20012367A patent/NO20012367L/no not_active Application Discontinuation
- 2001-06-07 BG BG105572A patent/BG105572A/xx unknown
-
2002
- 2002-04-12 HK HK02102769.3A patent/HK1040934A1/zh unknown
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