BG105276A - Pharmaceutical composition containing calcium valproate with delayed active substance release and method for the production of said composition - Google Patents
Pharmaceutical composition containing calcium valproate with delayed active substance release and method for the production of said compositionInfo
- Publication number
- BG105276A BG105276A BG105276A BG10527601A BG105276A BG 105276 A BG105276 A BG 105276A BG 105276 A BG105276 A BG 105276A BG 10527601 A BG10527601 A BG 10527601A BG 105276 A BG105276 A BG 105276A
- Authority
- BG
- Bulgaria
- Prior art keywords
- active substance
- production
- substance release
- containing calcium
- pharmaceutical composition
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title abstract 4
- 230000003111 delayed effect Effects 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 229940095670 calcium valproate Drugs 0.000 title abstract 2
- PIZHURYFCSGTJX-UHFFFAOYSA-L calcium;2-propylpentanoate Chemical compound [Ca+2].CCCC(C([O-])=O)CCC.CCCC(C([O-])=O)CCC PIZHURYFCSGTJX-UHFFFAOYSA-L 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- NIJJYAXOARWZEE-UHFFFAOYSA-N Valproic acid Chemical compound CCCC(C(O)=O)CCC NIJJYAXOARWZEE-UHFFFAOYSA-N 0.000 abstract 2
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 208000028683 bipolar I disease Diseases 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 229920000058 polyacrylate Polymers 0.000 abstract 1
- 229960000604 valproic acid Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19840152A DE19840152A1 (de) | 1998-09-03 | 1998-09-03 | Calciumvalproat enthaltende pharmazeutische Zusammensetzungen mit retardierter Wirkstoff-Freisetzung, Verfahren zu deren Herstellung und deren Verwendung |
| PCT/EP1999/006490 WO2000013711A1 (de) | 1998-09-03 | 1999-09-03 | Calciumvalproat enthaltende pharmazeutische zusammensetzungen mit retardierter wirkstoff-freisetzung und verfahren zu deren herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG105276A true BG105276A (en) | 2001-11-30 |
Family
ID=7879672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG105276A BG105276A (en) | 1998-09-03 | 2001-02-20 | Pharmaceutical composition containing calcium valproate with delayed active substance release and method for the production of said composition |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20020052411A1 (no) |
| EP (1) | EP1107792A1 (no) |
| AU (1) | AU5859799A (no) |
| BG (1) | BG105276A (no) |
| CZ (1) | CZ2001753A3 (no) |
| DE (1) | DE19840152A1 (no) |
| EA (1) | EA002695B1 (no) |
| HU (1) | HUP0201625A2 (no) |
| NO (1) | NO20011087L (no) |
| PL (1) | PL346474A1 (no) |
| SK (1) | SK2592001A3 (no) |
| WO (1) | WO2000013711A1 (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020083171A (ko) * | 2000-03-08 | 2002-11-01 | 아베데 파르마 게엠베하 운트 콤파니 카게 | 활성 성분의 방출 조절을 위한 삭카로스 지방산에스테르를 함유하는 약제학적 제제 |
| JP2007500770A (ja) * | 2003-07-28 | 2007-01-18 | マリンクロッド・インコーポレイテッド | 改善されたステアレート組成物およびその製法 |
| JP5269595B2 (ja) * | 2005-09-09 | 2013-08-21 | アンジェリーニ ラボファーム リミテッド ライアビリティ カンパニー | １日１回投与用トラゾドン組成物 |
| US20070160960A1 (en) * | 2005-10-21 | 2007-07-12 | Laser Shot, Inc. | System and method for calculating a projectile impact coordinates |
| US20090111733A1 (en) * | 2006-07-19 | 2009-04-30 | President And Fellows Of Harvard College | Par-4 related methods and compositions |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3063328D1 (en) * | 1979-08-20 | 1983-07-07 | Abbott Lab | Mixed salt of valproic acid |
| IL72381A (en) * | 1983-07-20 | 1988-03-31 | Sanofi Sa | Pharmaceutical composition based on valproic acid |
| CA1242738A (en) * | 1983-10-26 | 1988-10-04 | Abbott Laboratories | Acid salts of valproic acid |
| NL8600050A (nl) * | 1986-01-13 | 1987-08-03 | Sanico Nv | Farmaceutisch preparaat met vertraagde afgifte van het werkzame bestanddeel en werkwijze voor de bereiding er van. |
| JPS63101320A (ja) * | 1986-10-17 | 1988-05-06 | Dainippon Pharmaceut Co Ltd | バルプロ酸カルシウム製剤 |
| DE3709230A1 (de) * | 1987-03-20 | 1988-10-06 | Desitin Arzneimittel Gmbh | Neues calciumsalz der valproinsaeure |
| DD295543A5 (de) * | 1987-11-26 | 1991-11-07 | Univ Halle Wittenberg | Verfahren zur herstellung einer ca-valproat-arzneiform mit gleichmaessig verzoegerter wirkstofffreisetzung |
| FR2643556B1 (fr) * | 1989-02-27 | 1993-03-05 | Sanofi Sa | Composition pharmaceutique a liberation prolongee d'acide valproique |
| US6287598B1 (en) * | 1993-05-28 | 2001-09-11 | Alza Corporation | Method for providing sustained antiepileptic therapy |
-
1998
- 1998-09-03 DE DE19840152A patent/DE19840152A1/de not_active Ceased
-
1999
- 1999-09-03 EA EA200100309A patent/EA002695B1/ru not_active IP Right Cessation
- 1999-09-03 PL PL99346474A patent/PL346474A1/xx unknown
- 1999-09-03 WO PCT/EP1999/006490 patent/WO2000013711A1/de not_active Application Discontinuation
- 1999-09-03 EP EP99946111A patent/EP1107792A1/de not_active Withdrawn
- 1999-09-03 SK SK259-2001A patent/SK2592001A3/sk unknown
- 1999-09-03 HU HU0201625A patent/HUP0201625A2/hu unknown
- 1999-09-03 CZ CZ2001753A patent/CZ2001753A3/cs unknown
- 1999-09-03 AU AU58597/99A patent/AU5859799A/en not_active Abandoned
-
2001
- 2001-02-20 BG BG105276A patent/BG105276A/xx unknown
- 2001-02-27 US US09/794,318 patent/US20020052411A1/en not_active Abandoned
- 2001-03-02 NO NO20011087A patent/NO20011087L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20020052411A1 (en) | 2002-05-02 |
| WO2000013711A1 (de) | 2000-03-16 |
| DE19840152A1 (de) | 2000-03-09 |
| PL346474A1 (en) | 2002-02-11 |
| NO20011087D0 (no) | 2001-03-02 |
| AU5859799A (en) | 2000-03-27 |
| SK2592001A3 (en) | 2001-11-06 |
| HUP0201625A2 (en) | 2002-09-28 |
| CZ2001753A3 (cs) | 2001-08-15 |
| EA200100309A1 (ru) | 2001-08-27 |
| NO20011087L (no) | 2001-05-02 |
| EP1107792A1 (de) | 2001-06-20 |
| EA002695B1 (ru) | 2002-08-29 |
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