BG104092A - Сd154 блокадна терапия за лечение на белтък инхибиторен синдром - Google Patents
Сd154 блокадна терапия за лечение на белтък инхибиторен синдромInfo
- Publication number
- BG104092A BG104092A BG104092A BG10409200A BG104092A BG 104092 A BG104092 A BG 104092A BG 104092 A BG104092 A BG 104092A BG 10409200 A BG10409200 A BG 10409200A BG 104092 A BG104092 A BG 104092A
- Authority
- BG
- Bulgaria
- Prior art keywords
- treatment
- blockade therapy
- protein inhibition
- inhibition syndrome
- syndrome
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Abstract
Изобретението се отнася до методи, съгласно коитосе прилага блокатор на CD40:CD154 свързването, например CD154 блокиращ агент, за отслабване или подобрение на придобития биоинхибиторен хуморален имунитет, насочен срещу екзогенен белтък.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5027697P | 1997-06-20 | 1997-06-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
BG104092A true BG104092A (bg) | 2000-10-31 |
BG64436B1 BG64436B1 (en) | 2005-02-28 |
Family
ID=21964347
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG104092A BG64436B1 (en) | 1997-06-20 | 2000-01-18 | Cd154 blockade therapy for the treatment of protein inhibition syndrome |
Country Status (25)
Country | Link |
---|---|
US (1) | US20020119151A1 (bg) |
EP (1) | EP1034001B1 (bg) |
JP (1) | JP2002504910A (bg) |
KR (1) | KR100567998B1 (bg) |
CN (2) | CN1261285A (bg) |
AT (1) | ATE272408T1 (bg) |
AU (1) | AU733062B2 (bg) |
BG (1) | BG64436B1 (bg) |
BR (1) | BR9810755A (bg) |
CA (1) | CA2294138A1 (bg) |
CZ (1) | CZ295805B6 (bg) |
DE (1) | DE69825473T2 (bg) |
EA (1) | EA002512B1 (bg) |
EE (1) | EE9900587A (bg) |
ES (1) | ES2226152T3 (bg) |
HK (1) | HK1031825A1 (bg) |
HU (1) | HUP0002048A3 (bg) |
IL (1) | IL133305A0 (bg) |
IS (1) | IS2097B (bg) |
NO (1) | NO996274L (bg) |
NZ (1) | NZ502051A (bg) |
PT (1) | PT1034001E (bg) |
SK (1) | SK285962B6 (bg) |
TR (1) | TR199903141T2 (bg) |
WO (1) | WO1998058672A1 (bg) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA01002898A (es) * | 1998-09-21 | 2002-06-04 | Genetics Inst | Metodos de modulacion descendente de la respuesta inmune a proteinas terapeuticas. |
WO2001079555A2 (en) | 2000-04-14 | 2001-10-25 | Millennium Pharmaceuticals, Inc. | Roles of jak/stat family members in tolerance induction |
BR0110779A (pt) | 2000-05-12 | 2005-01-11 | Beth Israel Hospital | Composições e métodos para adquirir supressão imunológica |
IES20030299A2 (en) * | 2002-04-23 | 2003-10-29 | R Stephen Porter | Inhibition of platelet aggregation |
AU2011224032B2 (en) * | 2003-06-13 | 2013-01-31 | Biogen Ma Inc. | Aglycosyl Anti-CD154 (CD40 Ligand) Antibodies and Uses Thereof |
ES2353222T3 (es) * | 2003-06-13 | 2011-02-28 | Biogen Idec Ma Inc. | Anticuerpos anti-cd154 (ligando cd40) aglicosilados y usos de los mismos. |
AU2004253868B2 (en) * | 2003-06-13 | 2011-06-16 | Biogen Ma Inc. | Aglycosyl anti-CD154 (CD40 ligand) antibodies and uses thereof |
EP1694360B1 (en) | 2003-11-04 | 2010-08-04 | Novartis Vaccines and Diagnostics, Inc. | Use of antagonist anti-cd40 antibodies for treatment of autoimmune and inflammatory diseases and organ transplant rejection |
WO2006033702A2 (en) | 2004-07-26 | 2006-03-30 | Biogen Idec Ma Inc. | Anti-cd154 antibodies |
WO2006017574A1 (en) * | 2004-08-03 | 2006-02-16 | Mayo Foundation For Medical Education And Research | Improving treatments |
JP5421590B2 (ja) | 2005-05-18 | 2014-02-19 | ノバルティス アーゲー | 自己免疫および/または炎症性成分を有する疾患の診断および治療のための方法 |
EA018301B1 (ru) | 2006-04-21 | 2013-07-30 | Новартис Аг | Фармацевтические композиции, содержащие антагонистическое моноклональное антитело к cd40, и их применение |
US9382327B2 (en) | 2006-10-10 | 2016-07-05 | Vaccinex, Inc. | Anti-CD20 antibodies and methods of use |
AR083847A1 (es) | 2010-11-15 | 2013-03-27 | Novartis Ag | Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40 |
WO2012158789A2 (en) | 2011-05-17 | 2012-11-22 | St. Jude Children's Research Hospital | Methods and compositions for inhibiting neddylation of proteins |
US20140004131A1 (en) | 2012-05-04 | 2014-01-02 | Novartis Ag | Antibody formulation |
KR20210095781A (ko) | 2020-01-24 | 2021-08-03 | 주식회사 에이프릴바이오 | 항원결합 단편 및 생리활성 이펙터 모이어티로 구성된 융합 컨스트럭트를 포함하는 다중결합항체 및 이를 포함하는 약학조성물 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474771A (en) * | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
ZA946765B (en) * | 1993-09-02 | 1996-02-15 | Dartmouth College | Methods of prolonged suppression of humoral immunity |
US5872154A (en) * | 1995-02-24 | 1999-02-16 | The Trustees Of The University Of Pennsylvania | Method of reducing an immune response to a recombinant adenovirus |
DE69837322T2 (de) * | 1997-01-10 | 2007-11-22 | Biogen Idec Ma Inc., Cambridge | Verfahren zur therapeutischen verabreichung von anti-cd40l-mitteln |
-
1998
- 1998-06-19 TR TR1999/03141T patent/TR199903141T2/xx unknown
- 1998-06-19 KR KR1019997011990A patent/KR100567998B1/ko not_active IP Right Cessation
- 1998-06-19 CA CA002294138A patent/CA2294138A1/en not_active Abandoned
- 1998-06-19 EE EEP199900587A patent/EE9900587A/xx unknown
- 1998-06-19 DE DE69825473T patent/DE69825473T2/de not_active Expired - Fee Related
- 1998-06-19 CN CN98806403A patent/CN1261285A/zh active Pending
- 1998-06-19 NZ NZ502051A patent/NZ502051A/en unknown
- 1998-06-19 BR BR9810755-0A patent/BR9810755A/pt not_active Application Discontinuation
- 1998-06-19 CZ CZ19994588A patent/CZ295805B6/cs not_active IP Right Cessation
- 1998-06-19 PT PT98931391T patent/PT1034001E/pt unknown
- 1998-06-19 IL IL13330598A patent/IL133305A0/xx unknown
- 1998-06-19 HU HU0002048A patent/HUP0002048A3/hu unknown
- 1998-06-19 JP JP50339199A patent/JP2002504910A/ja not_active Ceased
- 1998-06-19 AU AU81536/98A patent/AU733062B2/en not_active Ceased
- 1998-06-19 AT AT98931391T patent/ATE272408T1/de not_active IP Right Cessation
- 1998-06-19 ES ES98931391T patent/ES2226152T3/es not_active Expired - Lifetime
- 1998-06-19 WO PCT/US1998/012773 patent/WO1998058672A1/en active IP Right Grant
- 1998-06-19 EP EP98931391A patent/EP1034001B1/en not_active Expired - Lifetime
- 1998-06-19 CN CNA2004100978650A patent/CN1651071A/zh active Pending
- 1998-06-19 EA EA200000059A patent/EA002512B1/ru not_active IP Right Cessation
- 1998-06-19 SK SK1803-99A patent/SK285962B6/sk unknown
-
1999
- 1999-11-26 IS IS5274A patent/IS2097B/is unknown
- 1999-12-17 NO NO996274A patent/NO996274L/no not_active Application Discontinuation
-
2000
- 2000-01-18 BG BG104092A patent/BG64436B1/bg unknown
-
2001
- 2001-02-14 HK HK01101074A patent/HK1031825A1/xx not_active IP Right Cessation
-
2002
- 2002-04-19 US US10/127,228 patent/US20020119151A1/en not_active Abandoned
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