BG101982A - Метод за изготвяне на форма 1 ренитидин хидрохлорид - Google Patents

Метод за изготвяне на форма 1 ренитидин хидрохлорид

Info

Publication number
BG101982A
BG101982A BG101982A BG10198297A BG101982A BG 101982 A BG101982 A BG 101982A BG 101982 A BG101982 A BG 101982A BG 10198297 A BG10198297 A BG 10198297A BG 101982 A BG101982 A BG 101982A
Authority
BG
Bulgaria
Prior art keywords
methyl
hydrochloride
ranitidine hydrochloride
preparing form
ranitidinehydrochloride
Prior art date
Application number
BG101982A
Other languages
English (en)
Inventor
Helmut Schickaneder
Aggelos NIKOPOULOS
Original Assignee
Hexal Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hexal Pharmaceuticals, Inc. filed Critical Hexal Pharmaceuticals, Inc.
Publication of BG101982A publication Critical patent/BG101982A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Методът включва изготвяне на чист N-[2-[[[5-[диметиламино]-метил-2-фуранил]метил]тио]етил]-N'-метил-2-нитро-1,1-етилдиаминхидрохлорид, обозначен катоформа 1 ранитидинхидрохлорид, от ранитидин в метиленхлорид с добавка на хлороводородна киселина. Получената форма 1 е стабилна и може да се използва при производството на търговски количества от нея.
BG101982A 1995-04-21 1997-10-20 Метод за изготвяне на форма 1 ренитидин хидрохлорид BG101982A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/426,930 US5663381A (en) 1995-04-21 1995-04-21 Process for preparing form 1 ranitidine hydrochloride
PCT/US1996/000992 WO1996033185A1 (en) 1995-04-21 1996-01-26 A process for preparing form 1 ranitidine hydrochloride

Publications (1)

Publication Number Publication Date
BG101982A true BG101982A (bg) 1998-04-30

Family

ID=23692783

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101982A BG101982A (bg) 1995-04-21 1997-10-20 Метод за изготвяне на форма 1 ренитидин хидрохлорид

Country Status (17)

Country Link
US (1) US5663381A (bg)
JP (1) JPH11503755A (bg)
KR (1) KR19990007912A (bg)
AU (1) AU691736B2 (bg)
BG (1) BG101982A (bg)
BR (1) BR9608177A (bg)
CA (1) CA2218562A1 (bg)
CZ (1) CZ332097A3 (bg)
EE (1) EE9700291A (bg)
FI (1) FI974002A (bg)
HU (1) HUP9801658A2 (bg)
NO (1) NO974846L (bg)
NZ (1) NZ302872A (bg)
PL (1) PL322979A1 (bg)
SI (1) SI9620056A (bg)
SK (1) SK143697A3 (bg)
WO (1) WO1996033185A1 (bg)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6004985A (en) * 1996-10-09 1999-12-21 Berlex Laboratories, Inc. Thio acid derived monocylic N-heterocyclics as anticoagulants
US6140351A (en) * 1997-12-19 2000-10-31 Berlex Laboratories, Inc. Ortho-anthranilamide derivatives as anti-coagulants
IT1317858B1 (it) 2000-02-29 2003-07-15 Pharmexcel S R L Allomorfo del cloridrato dell'isomero z di derivato dialchilamminofurano, procedimento per la sua produzione e composizione
US7439268B2 (en) * 2003-07-18 2008-10-21 Idexx Laboratories Compositions containing prodrugs of florfenicol and methods of use
ATE543817T1 (de) * 2003-07-29 2012-02-15 Dainippon Sumitomo Pharma Co Verfahren zur herstellung einer imidverbindung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
IL63968A (en) * 1980-10-01 1985-10-31 Glaxo Group Ltd Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
US5338871A (en) * 1991-12-20 1994-08-16 Torcan Chemical Ltd. Preparation of form 1 ranitidine hydrochloride

Also Published As

Publication number Publication date
JPH11503755A (ja) 1999-03-30
HUP9801658A2 (hu) 1999-09-28
NO974846L (no) 1997-12-19
WO1996033185A1 (en) 1996-10-24
MX9708122A (es) 1998-06-28
KR19990007912A (ko) 1999-01-25
AU691736B2 (en) 1998-05-21
CA2218562A1 (en) 1996-10-24
NO974846D0 (no) 1997-10-20
FI974002A (fi) 1997-12-03
AU4903296A (en) 1996-11-07
EE9700291A (et) 1998-06-15
PL322979A1 (en) 1998-03-02
CZ332097A3 (cs) 1998-03-18
SI9620056A (sl) 1998-04-30
SK143697A3 (en) 1998-05-06
US5663381A (en) 1997-09-02
BR9608177A (pt) 2000-10-31
NZ302872A (en) 1998-04-27
FI974002A0 (fi) 1997-10-20

Similar Documents

Publication Publication Date Title
IL117848A0 (en) Novel compounds a process for their production and pharmacetical compositions containing same
AU8229691A (en) Starch encapsulation of biologically active agents by a continuous process
CA2245151A1 (en) Improved process for obtaining insulin precursors having correctly bonded cystine bridges
AU7562296A (en) Novel amino acid derivatives, methods of producing them, and pharmaceutical compounds containing these compounds
AU6181394A (en) N-acyl-N,N',N'-ethylenediaminetriacetic acid derivatives and process for preparing same
HU9400186D0 (en) Using of n-cyclic and n,n'-dicyclic urea derivatives and process for producing thereof
MY121299A (en) A new process for the preparation of a pharmacologically active substance
SG44989A1 (en) Crystalline hydrochloride of (R)-(-)-2-{N-[4-(1,1-dioxid-3-oxo-2,3-dihydro-benzisothiazol-2-yl)-butyl]-aminomethyl}-chroman
EP0485636A4 (en) Indole derivative
MX9804226A (es) Derivados novedosos de 2,3,5-trimetil-4-hidroxianilida, su preparacion y su aplicacion de terapeutica.
PL326081A1 (en) Novel derivatives of amino acids, their production and application
LV10256B (en) Novel acylale of imidazole-5-carboxylic acid derivatives, process for producing thereof and using same
BG101982A (bg) Метод за изготвяне на форма 1 ренитидин хидрохлорид
HU9700060D0 (en) New compound, it's production and it's use as active component of a medicine
PL314745A1 (en) Derivatives of n-[(1,4-diazabicyclo[2.2.2]-oct-2-ylo)methyl]benzamide and method of obtaining them
HU9201575D0 (en) Pyrimidone derivatives and their analogues
WO2004007441A3 (fr) Derives de 4,4' -dithiobis- (3-aminobutane-1-sulfonates) nouveaux et compositions les contenant
PL343316A1 (en) Process for producing 5-hydroxybenzo[b]thiophene-3-carboxylic acid derivatives
AU1755092A (en) Preparation of 3'-substituted-2',3'-dideoxynucleosides and 2'-deoxynucleosides from acyclic, achiral precursors
AU1925392A (en) A process for the preparation of n-(2,6-dichlorophenyl)-n-phenyl-n-(chloroacetyl)-amine
UA41981C2 (uk) Біотинові сполуки, спосіб їх отримання, фармацевтична композиція та спосіб її отримання
CZ20011832A3 (cs) Nový farmaceutický přípravek a způsob jeho přípravy
MX9702506A (es) Suspensiones orales de sabeluzol.
EP0367233A3 (en) Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof
HUP9603150A3 (en) (sulfonylamino)benzoyl guanidine derivatives, process for producing them and pharmaceutical compositions containing them