BG100166A - Use of natural products and related synthetic compounds for the treatment of cardiovascular disease - Google Patents
Use of natural products and related synthetic compounds for the treatment of cardiovascular diseaseInfo
- Publication number
- BG100166A BG100166A BG100166A BG10016695A BG100166A BG 100166 A BG100166 A BG 100166A BG 100166 A BG100166 A BG 100166A BG 10016695 A BG10016695 A BG 10016695A BG 100166 A BG100166 A BG 100166A
- Authority
- BG
- Bulgaria
- Prior art keywords
- optionally substituted
- alkynyl
- alkenyl
- alkyl
- hydrogen
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 title 1
- 229930014626 natural product Natural products 0.000 title 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 4
- 125000000304 alkynyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000004450 alkenylene group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000006649 (C2-C20) alkynyl group Chemical group 0.000 abstract 1
- 125000006374 C2-C10 alkenyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 229930182470 glycoside Natural products 0.000 abstract 1
- 150000002338 glycosides Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
- C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
- C07C39/16—Bis-(hydroxyphenyl) alkanes; Tris-(hydroxyphenyl)alkanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
- C07C39/14—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with at least one hydroxy group on a condensed ring system containing two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
- C07C39/15—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with all hydroxy groups on non-condensed rings, e.g. phenylphenol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPL918193 | 1993-06-03 | ||
PCT/AU1994/000297 WO1994028886A1 (en) | 1993-06-03 | 1994-06-03 | Use of natural products and related synthetic compounds for the treatment of cardiovascular disease |
Publications (1)
Publication Number | Publication Date |
---|---|
BG100166A true BG100166A (en) | 1996-11-29 |
Family
ID=3776946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG100166A BG100166A (en) | 1993-06-03 | 1995-11-24 | Use of natural products and related synthetic compounds for the treatment of cardiovascular disease |
Country Status (16)
Country | Link |
---|---|
US (2) | US5741821A (xx) |
EP (1) | EP0703780A4 (xx) |
JP (1) | JPH09502163A (xx) |
KR (1) | KR960702749A (xx) |
CN (1) | CN1124922A (xx) |
BG (1) | BG100166A (xx) |
BR (1) | BR9406747A (xx) |
CA (1) | CA2164317A1 (xx) |
CZ (1) | CZ318795A3 (xx) |
FI (1) | FI955786A (xx) |
HU (1) | HUT74174A (xx) |
NO (1) | NO954479L (xx) |
PL (1) | PL311810A1 (xx) |
SI (1) | SI9420037A (xx) |
SK (1) | SK147995A3 (xx) |
WO (1) | WO1994028886A1 (xx) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6545131B1 (en) | 1997-05-19 | 2003-04-08 | The Johns Hopkins University | Tissue specific prodrug |
US6504014B1 (en) | 1997-05-19 | 2003-01-07 | The John Hopkins University | Tissue specific prodrug |
AU7582298A (en) | 1997-05-19 | 1998-12-11 | Johns Hopkins University School Of Medicine, The | Tissue specific prodrug |
US6538022B1 (en) | 1997-09-24 | 2003-03-25 | Orion Corporation | Compounds for deactivating phospholamban function on Ca-ATPase (phopholamban inhibitors) |
RU2137472C1 (ru) * | 1998-10-12 | 1999-09-20 | Тихоокеанский институт биоорганической химии Дальневосточного отделения РАН | Лекарственный препарат "гистохром" для лечения острого инфаркта миокарда и ишемической болезни сердца |
US6566560B2 (en) | 1999-03-22 | 2003-05-20 | Immugen Pharmaceuticals, Inc. | Resorcinolic compounds |
CA2369478A1 (en) * | 1999-04-15 | 2000-10-26 | Devgen Nv | Compound screening methods |
US7053042B1 (en) | 1999-07-29 | 2006-05-30 | Samuel Denmeade | Activation of peptide prodrugs by hK2 |
AU2002213429A1 (en) * | 2000-09-28 | 2002-04-08 | Immugen Pharmaceuticals, Inc. | Antiviral methods and compounds |
AU2001296402A1 (en) * | 2000-09-28 | 2002-04-08 | Immugen Pharmaceuticals, Inc. | Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation |
EP1206934A1 (en) * | 2000-11-15 | 2002-05-22 | B. Braun Melsungen Ag | Blockade of sodium channels by phenol derivatives |
KR100704299B1 (ko) * | 2005-11-17 | 2007-04-09 | 한국생명공학연구원 | 신규한 퀴놀린계 화합물, 및 지네 추출물 또는 이로부터 분리된 화합물을 포함하는 심장순환계 질환의 예방 및 치료용 조성물 |
US9024273B2 (en) * | 2010-04-20 | 2015-05-05 | Varian Semiconductor Equipment Associates, Inc. | Method to generate molecular ions from ions with a smaller atomic mass |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2321620A (en) * | 1940-10-10 | 1943-06-15 | Du Pont | Phenolic compounds |
DE3527862A1 (de) * | 1985-08-02 | 1987-02-05 | Bayer Ag | Verfahren zur herstellung von bis-hydroxyphenyl-n-alkanen, neue bis-hydroxyphenyl-n-alkane und neue alkandione |
-
1994
- 1994-06-03 SK SK1479-95A patent/SK147995A3/sk unknown
- 1994-06-03 PL PL94311810A patent/PL311810A1/xx unknown
- 1994-06-03 HU HU9503441A patent/HUT74174A/hu unknown
- 1994-06-03 EP EP94916850A patent/EP0703780A4/en not_active Withdrawn
- 1994-06-03 CA CA002164317A patent/CA2164317A1/en not_active Abandoned
- 1994-06-03 JP JP7501103A patent/JPH09502163A/ja active Pending
- 1994-06-03 WO PCT/AU1994/000297 patent/WO1994028886A1/en not_active Application Discontinuation
- 1994-06-03 CN CN94192317A patent/CN1124922A/zh active Pending
- 1994-06-03 CZ CZ953187A patent/CZ318795A3/cs unknown
- 1994-06-03 BR BR9406747A patent/BR9406747A/pt not_active Application Discontinuation
- 1994-06-03 SI SI9420037A patent/SI9420037A/sl unknown
- 1994-06-03 US US08/553,714 patent/US5741821A/en not_active Expired - Fee Related
-
1995
- 1995-11-08 NO NO954479A patent/NO954479L/no unknown
- 1995-11-24 BG BG100166A patent/BG100166A/xx unknown
- 1995-12-01 FI FI955786A patent/FI955786A/fi unknown
- 1995-12-02 KR KR1019950705432A patent/KR960702749A/ko not_active Application Discontinuation
-
1997
- 1997-11-12 US US08/969,145 patent/US5859067A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1124922A (zh) | 1996-06-19 |
JPH09502163A (ja) | 1997-03-04 |
EP0703780A1 (en) | 1996-04-03 |
PL311810A1 (en) | 1996-03-18 |
CA2164317A1 (en) | 1994-12-22 |
HUT74174A (en) | 1996-11-28 |
NO954479L (no) | 1996-02-02 |
BR9406747A (pt) | 1996-04-02 |
FI955786A (fi) | 1996-01-29 |
KR960702749A (ko) | 1996-05-23 |
EP0703780A4 (en) | 1998-01-07 |
HU9503441D0 (en) | 1996-01-29 |
CZ318795A3 (en) | 1996-06-12 |
WO1994028886A1 (en) | 1994-12-22 |
SK147995A3 (en) | 1997-04-09 |
SI9420037A (en) | 1996-08-31 |
US5741821A (en) | 1998-04-21 |
US5859067A (en) | 1999-01-12 |
FI955786A0 (fi) | 1995-12-01 |
NO954479D0 (no) | 1995-11-08 |
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