BE903122A - NOVEL PROCESSES FOR THE PREPARATION OF FURO- (3,4-C) -PYRIDINE DERIVATIVES SUSTITUTED IN POSITION 6 - Google Patents
NOVEL PROCESSES FOR THE PREPARATION OF FURO- (3,4-C) -PYRIDINE DERIVATIVES SUSTITUTED IN POSITION 6Info
- Publication number
- BE903122A BE903122A BE0/215502A BE215502A BE903122A BE 903122 A BE903122 A BE 903122A BE 0/215502 A BE0/215502 A BE 0/215502A BE 215502 A BE215502 A BE 215502A BE 903122 A BE903122 A BE 903122A
- Authority
- BE
- Belgium
- Prior art keywords
- furo
- preparation
- hydroxy
- sustituted
- pyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Nouveau procédé de préparation des dérivés de la dihydro-1,3 (hydroxy-1 diméthylaminométhyle-2 allyl)-6 hydroxy-7 furo-(3,4-c)-pyridine répondant à la formule générale II dans laquelle, chacun des groupements A1 et A2 représente divers substituants consistant à faire réagir le dérivé formyl-6 hydroxy-7 furo-(3,4-c)-pyridine rpondant à la formule générale 1 sur un léger excès de bromure de diméthylaminométhyle-1 vinylmagnésium, à l'ébullition, dans un solvant non polaire. Les dérivés de formule (II) présentent un interet thérapeutique dans le domaine de la diurèse, de l'abaissement de la tension artérielle et autres.New process for the preparation of 1,3-dihydro (1-hydroxy-dimethylaminomethyl-2 allyl) -6 hydroxy-7 furo- (3,4-c) -pyridine derivatives corresponding to general formula II in which, each of the groups A1 and A2 represent various substituents consisting in reacting the 6-formyl-7-hydroxy-furo (3,4-c) -pyridine derivative corresponding to general formula 1 with a slight excess of 1-dimethylaminomethyl-1 vinylmagnesium bromide, with boil, in a non-polar solvent. The derivatives of formula (II) have a therapeutic interest in the field of diuresis, lowering of blood pressure and others.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848422029A GB8422029D0 (en) | 1984-08-31 | 1984-08-31 | 6-substituted-furo-(3 4-c)-pyridine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BE903122A true BE903122A (en) | 1986-02-26 |
Family
ID=10566078
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/215502A BE903122A (en) | 1984-08-31 | 1985-08-26 | NOVEL PROCESSES FOR THE PREPARATION OF FURO- (3,4-C) -PYRIDINE DERIVATIVES SUSTITUTED IN POSITION 6 |
Country Status (22)
Country | Link |
---|---|
JP (1) | JPS6160688A (en) |
AR (1) | AR241455A1 (en) |
AT (1) | AT396590B (en) |
BE (1) | BE903122A (en) |
CA (1) | CA1300149C (en) |
CH (1) | CH666688A5 (en) |
DE (1) | DE3531004A1 (en) |
DK (1) | DK157871C (en) |
ES (1) | ES8604967A1 (en) |
FI (1) | FI82468C (en) |
FR (1) | FR2569698B1 (en) |
GB (2) | GB8422029D0 (en) |
HK (1) | HK6189A (en) |
IE (1) | IE58522B1 (en) |
IT (1) | IT1201459B (en) |
LU (1) | LU86052A1 (en) |
NL (1) | NL8502324A (en) |
NO (1) | NO162071C (en) |
OA (1) | OA08088A (en) |
PT (1) | PT81054B (en) |
SE (1) | SE462218B (en) |
ZA (1) | ZA856088B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8427218D0 (en) * | 1984-10-27 | 1984-12-05 | Scras | Pyridine derivatives |
GB8808001D0 (en) * | 1988-04-06 | 1988-05-05 | Scras | Stereospecific preparative process for furol(3,4-c)pyridine derivatives |
DE10323602A1 (en) * | 2003-05-19 | 2004-12-16 | Südzucker AG Mannheim/Ochsenfurt | Hard caramel for human consumption, contains hard caramel base and supported food color inhomogeneously distributed within hard caramel base |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA786269B (en) * | 1977-11-25 | 1979-10-31 | Scras | New pyridine derivative,its preparation and use |
ZA842029B (en) * | 1983-04-05 | 1984-10-31 | Scras | Furo-(3,4-c)-pyridine derivatives preparation thereof and therapeutic compositions containing the same |
GB2153824B (en) * | 1984-02-02 | 1987-04-01 | Scras | Furo-(3,4-c)-pyridine derivatives |
-
1984
- 1984-08-31 GB GB848422029A patent/GB8422029D0/en active Pending
-
1985
- 1985-08-12 ZA ZA856088A patent/ZA856088B/en unknown
- 1985-08-12 GB GB08520169A patent/GB2163744B/en not_active Expired
- 1985-08-19 SE SE8503869A patent/SE462218B/en not_active IP Right Cessation
- 1985-08-20 AR AR85301339A patent/AR241455A1/en active
- 1985-08-22 CA CA000489219A patent/CA1300149C/en not_active Expired - Fee Related
- 1985-08-22 LU LU86052A patent/LU86052A1/en unknown
- 1985-08-23 NL NL8502324A patent/NL8502324A/en not_active Application Discontinuation
- 1985-08-23 CH CH3653/85A patent/CH666688A5/en not_active IP Right Cessation
- 1985-08-26 BE BE0/215502A patent/BE903122A/en not_active IP Right Cessation
- 1985-08-28 FI FI853287A patent/FI82468C/en not_active IP Right Cessation
- 1985-08-29 AT AT0252985A patent/AT396590B/en not_active IP Right Cessation
- 1985-08-30 FR FR8512917A patent/FR2569698B1/en not_active Expired
- 1985-08-30 DE DE19853531004 patent/DE3531004A1/en active Granted
- 1985-08-30 IT IT22035/85A patent/IT1201459B/en active
- 1985-08-30 JP JP60190033A patent/JPS6160688A/en active Granted
- 1985-08-30 NO NO853418A patent/NO162071C/en unknown
- 1985-08-30 DK DK396085A patent/DK157871C/en not_active IP Right Cessation
- 1985-08-30 IE IE214385A patent/IE58522B1/en not_active IP Right Cessation
- 1985-08-30 ES ES546590A patent/ES8604967A1/en not_active Expired
- 1985-08-30 OA OA58669A patent/OA08088A/en unknown
- 1985-08-30 PT PT81054A patent/PT81054B/en not_active IP Right Cessation
-
1989
- 1989-01-19 HK HK61/89A patent/HK6189A/en not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: SOC. DE CONSEILS DE RECHERCHES ET D APPLICATION SC Effective date: 19980831 |