BE900882A - Derives de 2h-azeto(2,1-a)-isoquinoleine, procede pour les preparer et compositions pharmaceutiques les contenant. - Google Patents

Derives de 2h-azeto(2,1-a)-isoquinoleine, procede pour les preparer et compositions pharmaceutiques les contenant. Download PDF

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Publication number
BE900882A
BE900882A BE213875A BE213875A BE900882A BE 900882 A BE900882 A BE 900882A BE 213875 A BE213875 A BE 213875A BE 213875 A BE213875 A BE 213875A BE 900882 A BE900882 A BE 900882A
Authority
BE
Belgium
Prior art keywords
derivatives
azeto
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
BE213875A
Other languages
English (en)
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of BE900882A publication Critical patent/BE900882A/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Ces dérivés correspondant à la formule générale (I) dans laquelle R1 et R2 sont un radical hydroxy ou alcoxy contenant 1 à 6 atomes de carbone; R3 est un radical hydroxy, un atome de halogène ou un groupe -O-C(X)-R4, où R4 représente un groupe phényle, éventuellement substitué et X est un atome de soufre ou d'oxygène. Ces dérivés présentent une activité anti-pyrétique analgésique, anti-allergique et inhibitrice de la secrétion d'acide gastrique.
BE213875A 1983-10-25 1984-10-24 Derives de 2h-azeto(2,1-a)-isoquinoleine, procede pour les preparer et compositions pharmaceutiques les contenant. BE900882A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU833655A HU186810B (en) 1983-10-25 1983-10-25 Process for producing 2h-azeto/2,1-a/ isoquinoline-derivatives

Publications (1)

Publication Number Publication Date
BE900882A true BE900882A (fr) 1985-04-24

Family

ID=10964934

Family Applications (1)

Application Number Title Priority Date Filing Date
BE213875A BE900882A (fr) 1983-10-25 1984-10-24 Derives de 2h-azeto(2,1-a)-isoquinoleine, procede pour les preparer et compositions pharmaceutiques les contenant.

Country Status (14)

Country Link
US (1) US4622327A (fr)
JP (1) JPS60115582A (fr)
BE (1) BE900882A (fr)
CA (1) CA1253156A (fr)
CH (1) CH666271A5 (fr)
DE (1) DE3439157A1 (fr)
DK (1) DK158985C (fr)
FI (1) FI76799C (fr)
FR (1) FR2553772B1 (fr)
GB (1) GB2154234B (fr)
HU (1) HU186810B (fr)
IT (1) IT1196309B (fr)
NL (1) NL8403252A (fr)
SE (1) SE456585B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713386A (en) * 1986-09-22 1987-12-15 Mcneilab, Inc. Tetrahydroazeto [2,1-a]isoquinolines and methods for treating depression

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1145255A (en) * 1965-03-18 1969-03-12 Bristol Myers Co Tetrahydroisoquinolinium salts
GB1145254A (en) * 1965-03-18 1969-03-12 Bristol Myers Co Novel tetrahydroisoquinoline derivatives and a process for the preparation thereof
US3389141A (en) * 1966-05-16 1968-06-18 Bristol Myers Co 1-beta-aryloxyethyltetrahydro-isoquinolines
US3652544A (en) * 1968-12-18 1972-03-28 Squibb & Sons Inc 3 4-bisnor-5-aza-b-homo-d-homoandrostanes
GB1242175A (en) * 1969-03-11 1971-08-11 Biorex Laboratories Ltd A new isoquinoline derivative
US4140688A (en) * 1978-04-03 1979-02-20 Smithkline Corporation Tricyclic (azeto-isoquinoline) β-lactams
HU189764B (en) * 1983-10-25 1986-07-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing 1-(bis (substituted methyl)-methyl)-isoquinoline-derivatives

Also Published As

Publication number Publication date
DE3439157C2 (fr) 1992-10-08
CH666271A5 (de) 1988-07-15
FI844188A0 (fi) 1984-10-25
DK508784A (da) 1985-04-26
DK158985B (da) 1990-08-13
FI76799C (fi) 1988-12-12
DE3439157A1 (de) 1985-05-02
FR2553772B1 (fr) 1987-04-24
SE8405332L (sv) 1985-04-26
SE8405332D0 (sv) 1984-10-25
CA1253156A (fr) 1989-04-25
US4622327A (en) 1986-11-11
FI76799B (fi) 1988-08-31
DK158985C (da) 1991-01-14
GB8426943D0 (en) 1984-11-28
DK508784D0 (da) 1984-10-25
GB2154234A (en) 1985-09-04
HU186810B (en) 1985-09-30
IT8423306A1 (it) 1986-04-25
JPH0561275B2 (fr) 1993-09-06
SE456585B (sv) 1988-10-17
FI844188L (fi) 1985-04-26
JPS60115582A (ja) 1985-06-22
FR2553772A1 (fr) 1985-04-26
IT1196309B (it) 1988-11-16
IT8423306A0 (it) 1984-10-25
GB2154234B (en) 1986-10-29
NL8403252A (nl) 1985-05-17

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