BE875014A - Procede et reactif pour la determination de l'heparine active dans le plasma sanguin - Google Patents
Procede et reactif pour la determination de l'heparine active dans le plasma sanguinInfo
- Publication number
- BE875014A BE875014A BE194147A BE194147A BE875014A BE 875014 A BE875014 A BE 875014A BE 194147 A BE194147 A BE 194147A BE 194147 A BE194147 A BE 194147A BE 875014 A BE875014 A BE 875014A
- Authority
- BE
- Belgium
- Prior art keywords
- reagent
- determination
- blood plasma
- active heparin
- heparin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/10—Anilides
- C12Q2337/12—Para-Nitroanilides p-NA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
- G01N2333/8114—Kunitz type inhibitors
- G01N2333/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
- G01N2333/96444—Factor X (3.4.21.6)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/974—Thrombin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
- G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2812943A DE2812943C3 (de) | 1978-03-23 | 1978-03-23 | Verfahren und Reagens zur Bestimmung der biologischen Aktivität von Heparin im Plasma |
Publications (1)
Publication Number | Publication Date |
---|---|
BE875014A true BE875014A (fr) | 1979-09-24 |
Family
ID=6035376
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE194147A BE875014A (fr) | 1978-03-23 | 1979-03-22 | Procede et reactif pour la determination de l'heparine active dans le plasma sanguin |
Country Status (22)
Country | Link |
---|---|
US (1) | US4234682A (fr) |
EP (1) | EP0004271A3 (fr) |
JP (1) | JPS54128796A (fr) |
AR (1) | AR217503A1 (fr) |
AT (1) | AT362080B (fr) |
AU (1) | AU512206B2 (fr) |
BE (1) | BE875014A (fr) |
CA (1) | CA1111334A (fr) |
CH (1) | CH642749A5 (fr) |
DD (1) | DD141952A5 (fr) |
DE (1) | DE2812943C3 (fr) |
DK (1) | DK149475C (fr) |
FI (1) | FI62859C (fr) |
FR (1) | FR2420764A1 (fr) |
GB (1) | GB2017298B (fr) |
HU (1) | HU176068B (fr) |
IE (1) | IE48067B1 (fr) |
IT (1) | IT1112966B (fr) |
LU (1) | LU81070A1 (fr) |
NL (1) | NL7902259A (fr) |
SE (1) | SE445560B (fr) |
ZA (1) | ZA79622B (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2903701C2 (de) * | 1979-01-31 | 1980-10-16 | Boehringer Mannheim Gmbh, 6800 Mannheim | Kontrollreagens für die Bestimmung der Heparinaktivität |
US4244865A (en) * | 1979-12-03 | 1981-01-13 | Abbott Laboratories | α hydroxy tripeptide substrates |
DE3005540A1 (de) * | 1980-02-14 | 1981-08-20 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und reagens zur bestimmung der biologischen aktivitaet von heparin im plasma |
DE3019612A1 (de) * | 1980-05-22 | 1981-11-26 | Boehringer Mannheim Gmbh, 6800 Mannheim | Stabilisiertes thrombinpraeparat |
WO1982001377A1 (fr) * | 1980-10-09 | 1982-04-29 | Lill Helmut | Procede de determination d'une bm ('binding moderately') antithrombine |
US4473639A (en) * | 1982-09-15 | 1984-09-25 | Miles Laboratories, Inc. | Reagent strip test for antithrombin-III |
US4543335A (en) * | 1982-12-20 | 1985-09-24 | Miles Laboratories, Inc. | Device and method for the quantitative determination of heparin in mammalian blood plasma |
US4851336A (en) * | 1985-09-05 | 1989-07-25 | Yin E Thye | Composition, kit, and method for assaying heparinano a method for making the composition |
US4946775A (en) * | 1985-09-05 | 1990-08-07 | Yin E Thye | Composition, kit and method for assaying heparin and a method for making the composition |
US4948724A (en) * | 1985-09-05 | 1990-08-14 | Yin E Thye | Composition, kit and method for assaying heparin and a method for making the composition |
DE3679763D1 (de) * | 1985-09-05 | 1991-07-18 | E Thye Yin | Verfahren und zusammensetzungen zur bestimmung von heparin. |
EP0482088B1 (fr) * | 1989-07-20 | 1999-03-31 | Analytical Control Systems, Inc. | Regulations ameliorees pour effectuer une coagulation stable du sang |
US5939325A (en) * | 1989-07-20 | 1999-08-17 | Analytical Control Systems, Inc. | Stable whole blood coagulation controls |
DK0509086T3 (da) * | 1990-11-05 | 1995-07-03 | Dade Produktions Ag | Fremgangsmåde til bestemmelse af koncentrationen af antikoagulanter |
US5308755A (en) * | 1992-06-08 | 1994-05-03 | Research Corporation Technologies, Inc. | Method for measuring heparin |
EP1325962A1 (fr) * | 2001-12-17 | 2003-07-09 | Gentium S.p.A. | Procédé pour la détermination de l'activité biologique de la defibrotide |
WO2005111231A2 (fr) * | 2004-05-11 | 2005-11-24 | Heptest Laboratories, Inc. | Compositions, kit et procede en une etape permettant de surveiller des composes possedant des activites d'antifacteur xa et/ou d'antifacteur iia |
US7219827B2 (en) | 2004-11-19 | 2007-05-22 | General Electric Company | Braze end isolation layer for generator armature winding bar and method for applying the isolation layer |
DE102005038418A1 (de) * | 2005-08-12 | 2007-02-15 | Dade Behring Marburg Gmbh | Faktor Xa-basierter Heparinassay unter Verwendung einer Heparin-modifizierenden Komponente |
US8980862B2 (en) | 2010-11-12 | 2015-03-17 | Gentium S.P.A. | Defibrotide for use in prophylaxis and/or treatment of Graft versus Host Disease (GVHD) |
EP2484775A1 (fr) | 2011-02-07 | 2012-08-08 | Siemens Healthcare Diagnostics Products GmbH | Procédé non sensible à l'héparine destiné à la détermination d'inhibiteurs de facteurs de coagulation directs |
CN110079580B (zh) | 2012-06-22 | 2022-12-06 | 真蒂奥姆责任有限公司 | 用于测定去纤维蛋白多核苷酸的生物活性的基于优球蛋白的方法 |
EP2843416A1 (fr) | 2013-09-02 | 2015-03-04 | Siemens Healthcare Diagnostics Products GmbH | Matériau de contrôle et de calibrage pour la détermination d'anticoagulants directs |
EP3026122A1 (fr) | 2014-11-27 | 2016-06-01 | Gentium S.p.A. | Procédé à base cellulaire pour déterminer la puissance de défibrotide |
EP3348649A1 (fr) | 2017-01-16 | 2018-07-18 | Siemens Healthcare Diagnostics Products GmbH | Matériel de contrôle universel pour tests d'inhibiteur de facteur de coagulation |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3769617A (en) * | 1971-12-09 | 1973-10-30 | Rca Corp | Transmission line using a pair of staggered broad metal strips |
SE380257B (sv) * | 1972-05-02 | 1975-11-03 | Bofors Ab | Nya diagnostiskt verksamma substrat med hog specificitet till trombin och andra proteolytiska enzymer av typen peptidyl-peptid-hydrolaser |
US4162941A (en) * | 1974-12-05 | 1979-07-31 | Ab Kabi | Method for determining a proteolytic enzyme |
CH587439A5 (fr) * | 1974-12-10 | 1977-04-29 | Daimler Benz Ag | |
CH622286A5 (fr) * | 1975-06-23 | 1981-03-31 | Pentapharm Ag | |
SE407405B (sv) * | 1975-07-11 | 1979-03-26 | Kabi Ab | Nya kromogena trombinsubstrat |
US4061625A (en) * | 1975-07-11 | 1977-12-06 | Ab Kabi | Novel chromogenic thrombin substrates |
DE2601372C3 (de) * | 1976-01-15 | 1980-03-27 | Behringwerke Ag, 3550 Marburg | Verfahren zur Bestimmung von Antithrombin III |
NL7602423A (nl) * | 1976-03-08 | 1977-09-12 | Leuven Res & Dev Vzw | Bepaling van heparine in bloedplasma. |
US4067777A (en) * | 1976-05-13 | 1978-01-10 | Innerfield Irving | Determination of heparin in the blood |
-
1978
- 1978-03-23 DE DE2812943A patent/DE2812943C3/de not_active Expired
-
1979
- 1979-01-16 EP EP79100122A patent/EP0004271A3/fr not_active Withdrawn
- 1979-01-16 AT AT32179A patent/AT362080B/de not_active IP Right Cessation
- 1979-01-31 AU AU43825/79A patent/AU512206B2/en not_active Ceased
- 1979-02-07 DD DD79210876A patent/DD141952A5/de not_active IP Right Cessation
- 1979-02-07 CA CA321,067A patent/CA1111334A/fr not_active Expired
- 1979-02-07 JP JP1234279A patent/JPS54128796A/ja active Granted
- 1979-02-08 IE IE238/79A patent/IE48067B1/en not_active IP Right Cessation
- 1979-02-12 DK DK57079A patent/DK149475C/da active
- 1979-02-13 HU HU79BO1763A patent/HU176068B/hu not_active IP Right Cessation
- 1979-02-13 FI FI790476A patent/FI62859C/fi not_active IP Right Cessation
- 1979-02-13 ZA ZA79622A patent/ZA79622B/xx unknown
- 1979-02-14 AR AR275507A patent/AR217503A1/es active
- 1979-02-21 US US06/013,759 patent/US4234682A/en not_active Expired - Lifetime
- 1979-03-20 CH CH261079A patent/CH642749A5/de not_active IP Right Cessation
- 1979-03-21 GB GB7909974A patent/GB2017298B/en not_active Expired
- 1979-03-21 SE SE7902555A patent/SE445560B/sv not_active IP Right Cessation
- 1979-03-22 IT IT21220/79A patent/IT1112966B/it active
- 1979-03-22 BE BE194147A patent/BE875014A/fr not_active IP Right Cessation
- 1979-03-22 NL NL7902259A patent/NL7902259A/xx active Search and Examination
- 1979-03-23 FR FR7907424A patent/FR2420764A1/fr active Granted
- 1979-03-23 LU LU81070A patent/LU81070A1/de unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BE875014A (fr) | Procede et reactif pour la determination de l'heparine active dans le plasma sanguin | |
JPS5519097A (en) | Determining method and reagent of substance present in biological fluid | |
FR2277344A1 (fr) | Reactif et procede pour determiner les leucocytes et l'hemoglobine dans le sang | |
KR860700153A (ko) | 백혈구의 4가지 집단을 감별 결정하기 위한 방법과 시약체계 | |
BR8107873A (pt) | Prensa de alta velocidade e metodo de sua utilizacao | |
BE880817A (fr) | Procede des reactifs pour la determination de l'hemoglobine glucosylee dans le sang | |
DE3377285D1 (en) | Device and method for the quantitative determination of heparin in mammalian blood plasma and method for preparing the device | |
BE879914A (fr) | Procede et composition pour la determination directe de fer dans le serum sanguin | |
BE876053A (fr) | Reactif et methode de detection de l'hepatite b | |
BE875965A (fr) | Composition et reactif pour la mesure cinetique de concentration en glucose dans les fluides de l'organisme | |
BE861100A (fr) | Procede et agent pour la determination d'hydroperoxydes | |
FR2482729B1 (fr) | Procede et reactif pour la determination de la teneur en hemoglobine du sang | |
BE867952A (fr) | Procede et reactif pour le dosage de l'acide ascorbique | |
FR2580469B1 (fr) | Procede et dispositif pour la preparation de croissants | |
BE876204A (fr) | Composition en vue de reduire le taux de phenylalanine dans le sang, et son procede d'utilisation | |
FR2542620B1 (fr) | Filtre et procede pour l'obtention d'echantillons de plasma sanguin | |
FR2618351B1 (fr) | Emulsions gelifiees transparentes et leur procede d'obtention | |
FR2319130A1 (fr) | Methode et reactif pour la detection de l'hepatite serique | |
FR2475226B1 (fr) | Methode et reactif pour le dosage direct de l'ion chlorure dans le serum | |
PT89138A (pt) | Metodo de determinacao de concentracoes de colesterol total em amostras de sangue capilar | |
BE866414A (fr) | Procede et reactif pour le dosage de l'acide urique | |
BE891078A (fr) | Composition et procede pour l'electrodeposition rapide de l'argent | |
BE893362A (fr) | Procede de determination don isoenzymes cytoplasmique et mitochondrienne de la gutamate-oxalacetate-transaminase dans le serum ou le plasma humain | |
FR2594558B1 (fr) | Procede et dispositif pour determiner l'apparition de phenomenes de rearrangement dans le sol | |
BE870365A (fr) | Procede et reactif pour la determination de l'alpha-amylase |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: BOEHRINGER MANNHEIM G.M.B.H. Effective date: 19930331 |