BE868594A - Derives alpha-acetyleniques d'amines utiles notamment comme inhibiteurs de certaines decarboxylases et leur procede de preparation - Google Patents

Derives alpha-acetyleniques d'amines utiles notamment comme inhibiteurs de certaines decarboxylases et leur procede de preparation

Info

Publication number
BE868594A
BE868594A BE188954A BE188954A BE868594A BE 868594 A BE868594 A BE 868594A BE 188954 A BE188954 A BE 188954A BE 188954 A BE188954 A BE 188954A BE 868594 A BE868594 A BE 868594A
Authority
BE
Belgium
Prior art keywords
decarboxylases
inhibitors
alpha
certain
preparation process
Prior art date
Application number
BE188954A
Other languages
English (en)
French (fr)
Original Assignee
Merrell Toraude & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude & Co filed Critical Merrell Toraude & Co
Publication of BE868594A publication Critical patent/BE868594A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BE188954A 1977-07-01 1978-06-29 Derives alpha-acetyleniques d'amines utiles notamment comme inhibiteurs de certaines decarboxylases et leur procede de preparation BE868594A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/812,265 US4139563A (en) 1977-07-01 1977-07-01 α-ACETYLENIC DERIVATIVES OF AMINES

Publications (1)

Publication Number Publication Date
BE868594A true BE868594A (fr) 1978-10-16

Family

ID=25209053

Family Applications (1)

Application Number Title Priority Date Filing Date
BE188954A BE868594A (fr) 1977-07-01 1978-06-29 Derives alpha-acetyleniques d'amines utiles notamment comme inhibiteurs de certaines decarboxylases et leur procede de preparation

Country Status (14)

Country Link
US (1) US4139563A (sv)
JP (1) JPS5481206A (sv)
AU (1) AU517458B2 (sv)
BE (1) BE868594A (sv)
CA (1) CA1090790A (sv)
CH (1) CH640820A5 (sv)
DE (1) DE2827907A1 (sv)
ES (1) ES471269A1 (sv)
FR (1) FR2395990A1 (sv)
GB (1) GB2001058B (sv)
IT (1) IT1105054B (sv)
NL (1) NL190115C (sv)
NZ (1) NZ187543A (sv)
ZA (1) ZA783355B (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182891A (en) * 1977-07-01 1980-01-08 Merrell Toraude Et Compagnie α-Acetylenic derivatives of α-amino acids
US4456619A (en) * 1978-09-18 1984-06-26 Sandoz, Inc. Amides of 2-alkynoic acids and use for inhibiting accumulation of cholesterol ester in arterial walls
US4414395A (en) * 1980-03-13 1983-11-08 Ciba-Geigy Corporation Process for the manufacture of hydrazono-isoindolines
ZA811555B (en) * 1980-03-25 1982-03-31 Merrell Toraude & Co Substituted deoxyadenosine derivatives
AU544990B2 (en) * 1980-06-16 1985-06-27 Merrell Pharmaceuticals Inc. Antiprotozal composition containing amino compounds
US4437873A (en) 1981-03-23 1984-03-20 Merrell Dow Pharmaceuticals Inc. Method of inhibiting algae
IE54304B1 (en) * 1981-08-19 1989-08-16 Merrell Dow France Fluorinated diamino-heptene and -heptyne derivatives
US4376116A (en) * 1981-09-01 1983-03-08 Research Corporation Polyamine biosynthesis inhibitors
US4421768A (en) 1982-08-11 1983-12-20 Merrell Toraude Et Compagnie Fluorinated diamino-heptene and-heptyne derivatives
US4720489A (en) * 1984-10-15 1988-01-19 Douglas Shander Hair growth modification with ornithine decarboxylase inhibitors
JPS62148462A (ja) * 1985-12-19 1987-07-02 メレルダウフア−マス−テイカルズ　インコ−ポレ−テツド 原生動物の生長を抑制する新規な方法
US5196450A (en) * 1985-12-19 1993-03-23 Merrell Dow Pharmaceuticals Inc. Method of inhibiting protozoal growth
US4707498A (en) * 1986-01-14 1987-11-17 Merrell Dow Pharmaceuticals Inc. Fluorinated diaminoalkyne derivatives
US5366971A (en) * 1987-11-09 1994-11-22 Sandoz Ltd. Use of 11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them
PH26083A (en) * 1987-11-09 1992-02-06 Sandoz Ltd 11, 28-dioxa-4-azatricyclo [22.3.1.04.9) octacos-18-ene derivatives and pharmaceutical compositions containing them and method of use thereof
US5013719A (en) * 1988-05-13 1991-05-07 Merrell Dow Pharmaceuticals Inc. Method of effecting immunosuppression
AU2001268422A1 (en) 2000-06-15 2001-12-24 University Of Kentucky Research Foundation Agmatine and agmatine analogs in the treatment of epilepsy, seizure, and electroconvulsive disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2766285A (en) * 1952-10-20 1956-10-09 Lilly Co Eli Substituted aminopropynes and process for their preparation
US3024190A (en) * 1958-10-03 1962-03-06 Commercial Solvents Corp Process for the control of bacteria in a flooding process for the recovery of petroleum oil
US3160664A (en) * 1959-04-10 1964-12-08 Miles Lab Acetylenic omega-haloalkylamines
GB1041987A (en) * 1964-09-03 1966-09-07 Beecham Group Ltd Acetylenic compounds
US3291683A (en) * 1965-05-24 1966-12-13 American Cyanamid Co Controlling fungi and bacteria with alkoxy or alkylthio alkylamine ethers
FR1481067A (fr) * 1965-12-29 1967-05-19 Soc Ind Fab Antibiotiques Sifa Nouvelles nu-propynyl méthylamines et leurs sels et procédé de préparation
GB1161915A (en) * 1966-06-03 1969-08-20 Ciba Ltd Pharmaceutical Preparations comprising Sulphur-Containing Amino-Compounds for the Treatment of Depressive Conditions
US3960927A (en) * 1975-03-18 1976-06-01 Richardson-Merrell Inc. Olefinic derivatives of amino acids
FR2354100A2 (fr) * 1976-06-08 1978-01-06 Anvar Medicament a base de 5' thioethers de l'adenosine

Also Published As

Publication number Publication date
ES471269A1 (es) 1979-10-01
JPS5481206A (en) 1979-06-28
CA1090790A (en) 1980-12-02
FR2395990B1 (sv) 1980-07-18
FR2395990A1 (fr) 1979-01-26
NL190115C (nl) 1993-11-01
DE2827907C2 (sv) 1987-10-01
ZA783355B (en) 1979-06-27
US4139563A (en) 1979-02-13
JPS6216941B2 (sv) 1987-04-15
AU517458B2 (en) 1981-07-30
NL7807090A (nl) 1979-01-03
AU3732078A (en) 1980-01-03
NL190115B (nl) 1993-06-01
GB2001058B (en) 1982-02-03
GB2001058A (en) 1979-01-24
CH640820A5 (de) 1984-01-31
DE2827907A1 (de) 1979-01-11
IT7850078A0 (it) 1978-06-28
NZ187543A (en) 1982-03-30
IT1105054B (it) 1985-10-28

Similar Documents

Publication Publication Date Title
BE868594A (fr) Derives alpha-acetyleniques d'amines utiles notamment comme inhibiteurs de certaines decarboxylases et leur procede de preparation
BE896009A (fr) Nouveaux derives aryliques de la piperazine, leur procede de preparation et leur application en therapeutique
BE839657A (fr) Derives olefiniques d'aminoacides et procede de leur preparation
FR2313031A1 (fr) Derives d'anilides de l'acide cyanoacetique, leur procede de preparation et leur application
BE839658A (fr) Derives acetyleniques d'aminoacides et leur procede de preparation
FR2589152B1 (fr) Derives pyridine-3-carboxamides et leur application comme inhibiteurs de la croissance des plantes
BE863565A (fr) Nouveaux halogenacetanilides substitues sur l'azote, leur procede de preparation et leur application comme herbicides
BE853304A (fr) Nouveaux derives de 1,3,4,-thiadiazolyle, leur procede de preparation et leur application comme herbicides
BE846569A (fr) Nouveaux derives phenylacetiques utiles notamment comme hypolipemiants et leur procede de preparation
FR2528046B1 (fr) Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation
BE847915R (fr) Nouvelles cycloalcano (b) thienylurees substituees utiles notamment comme agents de croissance pour animaux et comme herbicides, et leur procede de preparation
LU79842A1 (fr) Nouveaux derives de l'acide amidinop-enicillanique et procede de preparation
FR2344538A1 (fr) Nouveaux derives de carbostyrile, utiles notamment comme b-bloquants cardio-selectifs, et leur procede de preparation
BE859480A (fr) Nouveaux derives de (1-phenyl-2-triazolyl-ethyl)-thioethers leur procede de preparation et leur application comme fongicides et substances de croissance
BE866548A (fr) Nouveaux derives d'acide naphtalenetris (sulfonamidobenzenemono-,di- ou tricarboxyliques), utiles notamment comme inhibiteurs du complement, et leur procede de preparation
BE875013A (fr) Nouveaux derives de 2-hydroxymethyl-pyrazine, utiles notamment comme hypolipemiants, et leur procede de preparation
FR2323690A1 (fr) Nouveaux derives de n-(1,2,4-triazine-5-one-4-yl)-glycine, leur procede de preparation et leur application comme herbicides
BE841165A (fr) Derives d'acides 8-aza-prostanoiques et leur procede de preparation
FR2320746A1 (fr) Nouveau thiopyranno(4,3-c)pyrasoles, utiles notamment comme anti-inflammatoires et leur procede de preparation
BE868591A (fr) Derives d'amines et d'amino-acides, leur procede d'obtention et leur utilisation notamment comme agents anti-infectieux et immunosuppresseurs
BE859629A (fr) Nouveaux derives 4,5-dichlorimidazoliques leur procede de preparation et leur application comme substances de croissance des plantes
BE868595A (fr) Nouveaux derives alpha-acetyleniques d'histamine utiles notamment comme antihistaminiques et leur procede de preparation
BE877687A (fr) Nouveaux derives de 20-methyl-13,14-bisdeshydro-pgi utiles notamment comme inhibiteurs de l'agglomeration des plaquettes et leur procede de preparation
BE866718A (fr) Nouveaux derives d'acides azolylalcane-carboxyliques, leur procede de preparation et leur application comme fongicides
FR2310771A1 (fr) Nouveaux sels d'((oxepannylidene-2)methyl)triphenylphosphonium, utiles notamment comme analgesiques et leur procede de preparation

Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: MERRELL TORAUDE ET CIE

Effective date: 19980629