GB1161915A - Pharmaceutical Preparations comprising Sulphur-Containing Amino-Compounds for the Treatment of Depressive Conditions - Google Patents
Pharmaceutical Preparations comprising Sulphur-Containing Amino-Compounds for the Treatment of Depressive ConditionsInfo
- Publication number
- GB1161915A GB1161915A GB24300/67D GB2430067D GB1161915A GB 1161915 A GB1161915 A GB 1161915A GB 24300/67 D GB24300/67 D GB 24300/67D GB 2430067 D GB2430067 D GB 2430067D GB 1161915 A GB1161915 A GB 1161915A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbon atoms
- sulphur
- pharmaceutical preparations
- treatment
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,161,915. Anti-depressants. CIBA Ltd.. 25 May, 1967 [3 June, 1966], No. 24330/67. Heading A5B. Pharmaceutical preparations for the treatment of depressive conditions comprise from 0.01 to 0.15 g. .per dosage unit of an arylmercapto - alky] amine compound of the general formula I P.h-S-Alk-NH. 2 (I) in which Ph represents a substituted or unsubstituted phenyl group and Alk represents an alkylene residue separating the sulphur from the nitrogen atom by at least two carbon atoms, or a physiologically tolerable acid addition salt of compound of the general formula I, in admixture or conjunction with a pharmaceutically acceptable carrier. The phenyl group may be substituted by one or more of lower alkyl; free, etherified or esterified hydroxyl groups; lower alkoxy or alkylenedioxy; halogen; trifluoromethyl; free or subtituted amino, eg alkylamino, acylamino or alkanoylamino; carboxyl; or carbo-lower alkoxy groups (lower indicates the presence of up to 7 carbon atoms). The alkylene radical preferably contains up to 7 carbon atoms. Salts may be formed with HC1, HBr, HNO 3 , H 2 SO 4 phosphoric, acetic propionic, glycollic, malonic, succinic, maleic, hydroxyma:leic, dihydroxymaleic, fumaric, malic, tartaric, citric, benzoic, cinnamic, mandelic, salicylic, 4-amino salicylic, 2-phenoxybenzoic, 2-acetoxy benzoic, embonic, glucuronic, nicotinic, isonicotinic, methanesulphonic, ethanesulphonic, 2-hydroxyethahesulphionic, 1, 2-ethanedisulphonic, benzenesulphonic, p-toluene sulphonic, 2-naphthalene sulphonic or N-cyolohexylsulphamic acids. The compositions may be administered orally, parenterally or rectally in the form of tablets, dragees, powders, suppositories, solutions, suspensions or emulsions containing conventional excipients.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH808566 | 1966-06-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1161915A true GB1161915A (en) | 1969-08-20 |
Family
ID=4334921
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB24300/67D Expired GB1161915A (en) | 1966-06-03 | 1967-05-25 | Pharmaceutical Preparations comprising Sulphur-Containing Amino-Compounds for the Treatment of Depressive Conditions |
Country Status (3)
Country | Link |
---|---|
US (1) | US3538228A (en) |
BE (1) | BE699422A (en) |
GB (1) | GB1161915A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0000573A1 (en) * | 1977-07-30 | 1979-02-07 | Bayer Ag | Process for the preparation of diamines containing a thioether group |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1288066A (en) * | 1968-09-16 | 1972-09-06 | ||
US4139563A (en) * | 1977-07-01 | 1979-02-13 | Merrell Toraude Et Compagnie | α-ACETYLENIC DERIVATIVES OF AMINES |
DE2734574A1 (en) * | 1977-07-30 | 1979-02-08 | Bayer Ag | THIOGROUPPIC POLYURETHANE PLASTICS |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2769839A (en) * | 1950-06-23 | 1956-11-06 | Monsanto Chemicals | Preparation of mercapto amines |
US2765338A (en) * | 1952-06-08 | 1956-10-02 | Cilag Ltd | New aliphatic acid amide derivatives and processes for the production thereof |
US3142554A (en) * | 1961-10-10 | 1964-07-28 | Monsanto Co | Controlling vegetation with aryl thioalkylamines |
GB1027611A (en) * | 1962-01-04 | 1966-04-27 | May & Baker Ltd | Phenoxy- and phenylthio-alkylamines and acid addition salts thereof |
US3205136A (en) * | 1962-12-24 | 1965-09-07 | Smith Kline French Lab | Antidepressant phenyloxyalkylamines |
-
1967
- 1967-05-25 GB GB24300/67D patent/GB1161915A/en not_active Expired
- 1967-06-02 BE BE699422D patent/BE699422A/xx unknown
-
1968
- 1968-06-10 US US735584A patent/US3538228A/en not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0000573A1 (en) * | 1977-07-30 | 1979-02-07 | Bayer Ag | Process for the preparation of diamines containing a thioether group |
Also Published As
Publication number | Publication date |
---|---|
US3538228A (en) | 1970-11-03 |
BE699422A (en) | 1967-12-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PLNP | Patent lapsed through nonpayment of renewal fees |