BE867269A - Derives de thiopropanoylamino-acides - Google Patents

Derives de thiopropanoylamino-acides

Info

Publication number
BE867269A
BE867269A BE187862A BE187862A BE867269A BE 867269 A BE867269 A BE 867269A BE 187862 A BE187862 A BE 187862A BE 187862 A BE187862 A BE 187862A BE 867269 A BE867269 A BE 867269A
Authority
BE
Belgium
Prior art keywords
thiopropanoylamino
acid derivatives
derivatives
acid
Prior art date
Application number
BE187862A
Other languages
English (en)
French (fr)
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of BE867269A publication Critical patent/BE867269A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
BE187862A 1977-03-11 1978-05-19 Derives de thiopropanoylamino-acides BE867269A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/776,792 US4108886A (en) 1977-03-11 1977-03-11 Thiopropanoylamino acid derivatives

Publications (1)

Publication Number Publication Date
BE867269A true BE867269A (fr) 1978-11-20

Family

ID=25108379

Family Applications (1)

Application Number Title Priority Date Filing Date
BE187862A BE867269A (fr) 1977-03-11 1978-05-19 Derives de thiopropanoylamino-acides

Country Status (7)

Country Link
US (1) US4108886A (xx)
JP (1) JPS53112810A (xx)
BE (1) BE867269A (xx)
CA (1) CA1090355A (xx)
DE (1) DE2810261A1 (xx)
FR (1) FR2383171A1 (xx)
GB (1) GB1593712A (xx)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT7851510A0 (it) * 1977-10-28 1978-10-16 Sandoz Ag Ammidi di amminoacidi ciclici loro preparazione e loro applicazione quali medicamenti
US4241076A (en) * 1978-02-21 1980-12-23 E. R. Squibb & Sons, Inc. Halogenated substituted mercaptoacylamino acids
IT1098328B (it) * 1978-06-16 1985-09-07 Gargani Pietro Sale sodico della mercapropropionilglicina,processo per la sua preparazione e suoi impieghi terapeutici
CA1144930A (en) * 1978-08-11 1983-04-19 Miguel A. Ondetti Mercaptoacyl derivatives of substituted prolines
JPS5531022A (en) * 1978-08-24 1980-03-05 Yoshitomi Pharmaceut Ind Ltd Hydroxamic acid derivative and its preparation
ZA794723B (en) * 1978-09-11 1980-08-27 Univ Miami Anti-hypertensive agents
US4690938A (en) * 1979-08-14 1987-09-01 University Of Miami Anti-hypertensive agents
US4690939A (en) * 1979-08-14 1987-09-01 University Of Miami Anti-hypertensive agents
US4698356A (en) * 1979-08-14 1987-10-06 University Of Miami Anti-hypertensive agents
US4690937A (en) * 1979-08-14 1987-09-01 University Of Miami Anti-hypertensive agents
US4695577A (en) * 1979-08-14 1987-09-22 University Of Miami Anti-hypertensive agents
US4690940A (en) * 1979-08-14 1987-09-01 University Of Miami Anti-hypertensive agents
US4698355A (en) * 1979-08-14 1987-10-06 University Of Miami Anti-hypertensive agents
GR73585B (xx) * 1978-09-11 1984-03-26 Univ Miami
JPS5829950B2 (ja) * 1978-10-05 1983-06-25 ウェルファイド株式会社 環状イミノカルボン酸誘導体およびその塩類
US4198515A (en) * 1978-12-08 1980-04-15 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids
IT1111384B (it) * 1978-12-21 1986-01-13 Sigma Tau Ind Farmaceuti Guaiacil esteri di derivati dello acido mercaptopropionico procedimento per la loro preparazione e loro uso terapeutico
EP0015544B1 (en) * 1979-03-06 1983-01-05 ZAMBON S.p.A. Derivatives of the mercaptopropionamido-acetic acid, process for the preparation thereof and compositions
JPS55164673A (en) * 1979-06-08 1980-12-22 Yoshitomi Pharmaceut Ind Ltd Zinc compound and its preparation
US4256761A (en) * 1979-07-13 1981-03-17 Usv Pharmaceutical Corporation Antihypertensive amides
US4291040A (en) * 1979-10-22 1981-09-22 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines
GB2065643B (en) * 1979-12-13 1983-08-24 Kanegafuchi Chemical Ind Optically active n-mercaptoalkanoylamino acids
US4690936A (en) * 1980-03-05 1987-09-01 University Of Miami Anti-hypertensive agents
US4734420A (en) * 1980-03-05 1988-03-29 University Of Miami Anti-hypertensive agents
AU542211B2 (en) * 1980-03-07 1985-02-14 Gruppo Lepetit S.P.A. Mercaptocycloalkyl carbonyl prolines
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
ZA811340B (en) * 1980-06-09 1982-03-31 Morton Norwich Products Inc N-(cycloalkyl)amino acid compounds
US4316905A (en) * 1980-07-01 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of various 4-substituted prolines
US4512979A (en) * 1981-03-23 1985-04-23 Merck & Co., Inc. Dipeptides containing thialysine and related amino acids as antihypertensives
IE52884B1 (en) * 1981-05-11 1988-03-30 Sigma Tau Ind Farmaceuti 2-methoxyphenyl esters of n-substituted amino acids, their preparation and pharmaceutical use
IT1140394B (it) * 1981-12-23 1986-09-24 Maggioni Farma Dipeptidi contenenti un residuo di metionina ad attivita' epatoprotettrice
US4634716A (en) * 1982-09-30 1987-01-06 Merck & Co., Inc. Substituted N-carboxymethyl-aminoacylaminoalkanoic acids useful as antihypertensive agents
US5760241A (en) * 1995-12-28 1998-06-02 Zambon Group S.P.A. Thiol derivatives with metallopeptidase inhibitory activity
JP4525885B2 (ja) * 2001-01-12 2010-08-18 三菱瓦斯化学株式会社 フォトレジスト用現像液及びフォトレジストの現像方法
CN103130692B (zh) * 2011-12-02 2016-09-14 天津市国际生物医药联合研究院 3-巯基丙酰胺类化合物在抑制ndm-1活性中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3098078A (en) * 1958-02-19 1963-07-16 Ciba Geigy Corp Thio alkane carboxylic acids and functional derivatives thereof
FR1491204A (fr) * 1962-08-10 1967-08-11 Santen Pharmaceutical Co Ltd Procédés pour la préparation des alpha-et beta mercaptopropionylglycocolle et de leurs dérivés
CA946837A (en) * 1970-07-28 1974-05-07 Miguel A. Ondetti Enzyme inhibitor
CA1009252A (en) * 1972-10-03 1977-04-26 Santen Pharmaceutical Co. N-(mercaptoacyl) aminoacids
JPS6058230A (ja) * 1983-09-09 1985-04-04 Babcock Hitachi Kk 排煙脱硫方法および装置

Also Published As

Publication number Publication date
US4108886A (en) 1978-08-22
JPS6216944B2 (xx) 1987-04-15
FR2383171B1 (xx) 1980-04-11
CA1090355A (en) 1980-11-25
FR2383171A1 (fr) 1978-10-06
GB1593712A (en) 1981-07-22
DE2810261C2 (xx) 1988-04-28
JPS53112810A (en) 1978-10-02
DE2810261A1 (de) 1978-09-14

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: E.R. SQUIBB & SONS INC.

Effective date: 19930531