BE857708A - (((diphenylmethyl)-4 piperidino)methyl)-4 benzenamines et procedes de leur preparation - Google Patents

(((diphenylmethyl)-4 piperidino)methyl)-4 benzenamines et procedes de leur preparation

Info

Publication number
BE857708A
BE857708A BE180100A BE180100A BE857708A BE 857708 A BE857708 A BE 857708A BE 180100 A BE180100 A BE 180100A BE 180100 A BE180100 A BE 180100A BE 857708 A BE857708 A BE 857708A
Authority
BE
Belgium
Prior art keywords
benzenamines
diphenylmethyl
piperidino
methyl
preparation
Prior art date
Application number
BE180100A
Other languages
English (en)
French (fr)
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of BE857708A publication Critical patent/BE857708A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE180100A 1976-08-13 1977-08-11 (((diphenylmethyl)-4 piperidino)methyl)-4 benzenamines et procedes de leur preparation BE857708A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/714,429 US4035372A (en) 1976-08-13 1976-08-13 4-{[4-(Diphenylmethyl)-1-piperidinyl]methyl}benzenamines

Publications (1)

Publication Number Publication Date
BE857708A true BE857708A (fr) 1978-02-13

Family

ID=24870002

Family Applications (1)

Application Number Title Priority Date Filing Date
BE180100A BE857708A (fr) 1976-08-13 1977-08-11 (((diphenylmethyl)-4 piperidino)methyl)-4 benzenamines et procedes de leur preparation

Country Status (18)

Country Link
US (1) US4035372A (ja)
JP (1) JPS5323982A (ja)
AT (2) AT366031B (ja)
AU (1) AU506432B2 (ja)
BE (1) BE857708A (ja)
CA (1) CA1095523A (ja)
DE (1) DE2736201A1 (ja)
DK (1) DK359177A (ja)
ES (1) ES461543A1 (ja)
FR (1) FR2361367A1 (ja)
GB (1) GB1531949A (ja)
GR (1) GR71900B (ja)
IE (1) IE45402B1 (ja)
IL (1) IL52706A (ja)
NL (1) NL7708978A (ja)
NZ (1) NZ184902A (ja)
SE (1) SE7709135L (ja)
ZA (1) ZA774910B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4256891A (en) * 1978-05-08 1981-03-17 Mcneil Laboratories, Inc. (2-Amino-2-oxoethoxy)acetic acid compounds
US4650874A (en) * 1984-11-26 1987-03-17 G. D. Searle & Co. N-(aralkoxybenzyl)-4(benzhydryl) piperidines
US4628095A (en) * 1985-06-05 1986-12-09 G. D. Searle & Co. Substituted N-benzyl-4-(benzhydryl) piperidines
EP0235463A3 (en) * 1985-12-20 1990-01-17 A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents
IL78939A (en) * 1986-01-17 1990-04-29 Robins Co Inc A H Pharmaceutical compositions containing n-substituted arylalkyl-and arylalkylene-piperidines and tetrahydropyridines and certain such novel compounds
JPH01240821A (ja) * 1988-03-23 1989-09-26 Hamamatsu Photonics Kk ロータリエンコーダ
US5070087A (en) * 1989-05-08 1991-12-03 A. H. Robins Company, Incorporated Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents
KR100377280B1 (ko) * 1993-01-21 2003-07-18 메렐 파마슈티칼스 인크. 디아릴알킬피페리딘을함유하는다중-약물내성종양치료효력증강용약제학적조성물
US5569664A (en) * 1995-02-16 1996-10-29 Fmc Corporation Insecticidal n-(substituted arylmethyl)-4-[bis(substituted phenyl) methyl]pi
US6017931A (en) * 1994-03-01 2000-01-25 Fmc Corporation Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US5670521A (en) * 1994-08-05 1997-09-23 Merrell Pharmaceuticals Inc. Reversal of multi-drug resistance by triphenyl-azacycloalkane derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3068237A (en) * 1961-03-17 1962-12-11 Searle & Co N-[(chloro/nitro/amino)phenylalkyl]-alpha, alpha-diphenylpipidinemethanols
US3081303A (en) * 1961-10-13 1963-03-12 Searle & Co 1-aminoalkyl-alpha, alpha-diphenylpiperidine-methanols
GB1252315A (ja) * 1969-06-05 1971-11-03
US3946022A (en) * 1974-03-04 1976-03-23 Richardson-Merrell Inc. Piperidine derivatives

Also Published As

Publication number Publication date
DE2736201C2 (ja) 1989-03-16
DE2736201A1 (de) 1978-02-16
ES461543A1 (es) 1978-06-01
AU2784277A (en) 1979-02-15
JPS6134413B2 (ja) 1986-08-07
IE45402B1 (en) 1982-08-11
FR2361367B1 (ja) 1980-07-18
IL52706A0 (en) 1977-10-31
AT358581B (de) 1980-09-25
CA1095523A (en) 1981-02-10
ATA587777A (de) 1980-02-15
US4035372A (en) 1977-07-12
ATA418179A (de) 1981-07-15
AU506432B2 (en) 1980-01-03
GR71900B (ja) 1983-08-11
DK359177A (da) 1978-02-14
IL52706A (en) 1980-09-16
ZA774910B (en) 1978-09-27
GB1531949A (en) 1978-11-15
NL7708978A (nl) 1978-02-15
IE45402L (en) 1978-02-13
AT366031B (de) 1982-03-10
FR2361367A1 (fr) 1978-03-10
NZ184902A (en) 1980-05-08
JPS5323982A (en) 1978-03-06
SE7709135L (sv) 1978-02-14

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: G.D. SEARLE & CO.

Effective date: 19840811