BE854683A - Benzamides n-acyle substitues, procede pour leur preparation et medicament contenant de tels benzamides - Google Patents

Benzamides n-acyle substitues, procede pour leur preparation et medicament contenant de tels benzamides

Info

Publication number
BE854683A
BE854683A BE177612A BE177612A BE854683A BE 854683 A BE854683 A BE 854683A BE 177612 A BE177612 A BE 177612A BE 177612 A BE177612 A BE 177612A BE 854683 A BE854683 A BE 854683A
Authority
BE
Belgium
Prior art keywords
benzamides
acyl
substitute
preparation
product containing
Prior art date
Application number
BE177612A
Other languages
English (en)
French (fr)
Inventor
G Metz
M Specker
Original Assignee
Merckle Kg Chem Pharm L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merckle Kg Chem Pharm L filed Critical Merckle Kg Chem Pharm L
Publication of BE854683A publication Critical patent/BE854683A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE177612A 1976-05-24 1977-05-16 Benzamides n-acyle substitues, procede pour leur preparation et medicament contenant de tels benzamides BE854683A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2623228A DE2623228C3 (de) 1976-05-24 1976-05-24 N-Acyl-substituierte Benzamide, Verfahren zu ihrer Herstellung und Arzneimittel, enthaltend solche Benzamide

Publications (1)

Publication Number Publication Date
BE854683A true BE854683A (fr) 1977-11-16

Family

ID=5978871

Family Applications (1)

Application Number Title Priority Date Filing Date
BE177612A BE854683A (fr) 1976-05-24 1977-05-16 Benzamides n-acyle substitues, procede pour leur preparation et medicament contenant de tels benzamides

Country Status (9)

Country Link
US (1) US4146637A (xx)
AT (1) AT348990B (xx)
BE (1) BE854683A (xx)
CA (1) CA1091247A (xx)
CH (1) CH633259A5 (xx)
DE (1) DE2623228C3 (xx)
FR (1) FR2352791A1 (xx)
GB (1) GB1555723A (xx)
NL (1) NL187437C (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10647661B2 (en) 2017-07-11 2020-05-12 Vertex Pharmaceuticals Incorporated Carboxamides as modulators of sodium channels

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2730174C2 (de) * 1977-07-04 1981-12-10 Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren Aminobenzoesäurederivate und Arzneimittel enthaltend solche Aminobenzoesäurederivate
US4251263A (en) * 1979-09-04 1981-02-17 Stauffer Chemical Company N-substituted, 2-phenoxynicotinamide compounds and the herbicidal use thereof
ZA86171B (en) * 1985-01-16 1986-08-27 Hoffmann La Roche Polycyclic salts
US6100299A (en) * 1996-03-08 2000-08-08 Oxigene, Inc. N-acetyl 3-chloroprocainamide, acid addition salts thereof, and methods of use
US6028111A (en) * 1996-03-08 2000-02-22 Oxigene, Inc. Compositions and use of benzamides and nicotinamides as anti-inflammatory agents
JP3933244B2 (ja) * 1997-04-04 2007-06-20 株式会社資生堂 アルキレンジアミン誘導体及び抗潰瘍剤、抗菌剤
SE9901875D0 (sv) * 1999-05-25 1999-05-25 Astra Pharma Prod Novel compounds
ES2293980T3 (es) * 2000-01-13 2008-04-01 Amgen Inc. Agentes antibacterianos.
US20060235035A1 (en) * 2002-04-09 2006-10-19 7Tm Pharma A/S Novel methoxybenzamibe compounds for use in mch receptor related disorders
US7351719B2 (en) * 2002-10-31 2008-04-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds
WO2004048319A1 (en) * 2002-11-25 2004-06-10 7Tm Pharma A/S Novel benzamide compounds for use in mch receptor related disorders
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
EP2526948A1 (en) * 2006-09-20 2012-11-28 Aerie Pharmaceuticals, Inc. RHO kinase inhibitors
US8455513B2 (en) 2007-01-10 2013-06-04 Aerie Pharmaceuticals, Inc. 6-aminoisoquinoline compounds
KR20180049144A (ko) * 2007-06-04 2018-05-10 테크필즈 인크 매우 높은 피부 및 막 침투율을 가지는 비스테로이드성 소염제(ｎｓａｉａ) 약물전구체 및 이들의 새로운 의약적 용도
US8455514B2 (en) * 2008-01-17 2013-06-04 Aerie Pharmaceuticals, Inc. 6-and 7-amino isoquinoline compounds and methods for making and using the same
US8450344B2 (en) 2008-07-25 2013-05-28 Aerie Pharmaceuticals, Inc. Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
JP2012511027A (ja) 2008-12-04 2012-05-17 チョンシー ユー 高透過性組成物およびその用途
CA2929545C (en) 2009-05-01 2019-04-09 Aerie Pharmaceuticals, Inc. Dual mechanism inhibitors for the treatment of disease
EP4335507A3 (en) 2013-03-15 2024-06-05 Aerie Pharmaceuticals, Inc. Combination therapy
EP3101006A1 (en) * 2015-06-05 2016-12-07 Lead Pharma Cel Models IP B.V. Ror gamma (rory) modulators
AU2015414743B2 (en) 2015-11-17 2019-07-18 Alcon Inc. Process for the preparation of kinase inhibitors and intermediates thereof
US9643927B1 (en) 2015-11-17 2017-05-09 Aerie Pharmaceuticals, Inc. Process for the preparation of kinase inhibitors and intermediates thereof
MX2019002396A (es) 2016-08-31 2019-07-08 Aerie Pharmaceuticals Inc Composiciones oftalmicas.
MX2019011784A (es) 2017-03-31 2019-11-18 Aerie Pharmaceuticals Inc Compuestos de aril ciclopropil-amino-isoquinolinil amida.
CA3112391A1 (en) 2018-09-14 2020-03-19 Aerie Pharmaceuticals, Inc. Aryl cyclopropyl-amino-isoquinolinyl amide compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR8120M (xx) * 1968-12-26 1970-08-03
US3898278A (en) * 1973-04-02 1975-08-05 Menarini Sas Substituted N-phenylbenzamides
GB1438612A (en) * 1974-02-08 1976-06-09 Biorex Laboratories Ltd Glycyrrhetinic acid derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10647661B2 (en) 2017-07-11 2020-05-12 Vertex Pharmaceuticals Incorporated Carboxamides as modulators of sodium channels
US11603351B2 (en) 2017-07-11 2023-03-14 Vertex Pharmaceuticals Incorporated Carboxamides as modulators of sodium channels

Also Published As

Publication number Publication date
ATA348877A (de) 1978-08-15
NL187437C (nl) 1991-10-01
DE2623228B2 (xx) 1979-06-21
DE2623228C3 (de) 1981-09-10
AT348990B (de) 1979-03-12
DE2623228A1 (de) 1977-12-01
FR2352791B1 (xx) 1979-03-09
NL7705630A (nl) 1977-11-28
FR2352791A1 (fr) 1977-12-23
CA1091247A (en) 1980-12-09
US4146637A (en) 1979-03-27
NL187437B (nl) 1991-05-01
GB1555723A (en) 1979-11-14
CH633259A5 (de) 1982-11-30

Similar Documents

Publication Publication Date Title
BE854683A (fr) Benzamides n-acyle substitues, procede pour leur preparation et medicament contenant de tels benzamides
BE855405A (fr) Nouvelles 4-amino-4-arylcyclohexanones, leur procede de preparation et medicament les contenant
BE860726A (fr) Nouveaux aryl-acylamides n-(2-aminocy-cloaliphatiques), leur procede de preparation et medicament les contenant
BE860727A (fr) Nouveaux benzamides trans-n-(2-aminocycloaliphatiques), leur procede de preparation et medicament les contenant
FR2323387A1 (fr) Nouveaux benzylates quaternaires de n-alcoyl-nortropines n-b-substituees, procede pour leur preparation et medicament en renfermant
BE829052A (fr) Nouvelles phenylguanidines substituees, leur procede de preparation et medicament les contenant
BE884189A (fr) Nouveaux aryl-1 arylsulfonyl-4 gamma-aminopropoxy-3, 1h-pyrazoles, medicament en contenant et procede pour les preparer
FR2328466A1 (fr) Nouvelles 4-aminopyrazoles substituees, procede pour leur preparation et medicaments contenant ces composes
FR2346324A1 (fr) Nouvelles amidino-urees, procede pour leur preparation et medicaments les renfermant
FR2338936A1 (fr) Nouvelles 1,2-benzisothiazolinones-3, leur procede de preparation et medicament les contenant
BE858269A (fr) Nouvelles aminoalkylidenamino-1,4-dihydropyridines, leur procede de preparation et medicament les contenant
BE857289A (fr) 2-benzyl-pyrrolidines, procede pour leur preparation et medicaments contenant ces composes
BE865601A (fr) Medicaments contenant des alcenylxanthines et leur procede de preparation
FR2342069A1 (fr) Nouvelles benzodiazepinones, leur procede de preparation et medicament les contenant
FR2278330A1 (fr) Nouvelles phenylisothiourees substituees, leur procede de preparation et medicament les contenant
FR2346354A1 (fr) Nouvelles as-triazinobenzodiazepine-1-ones, leur procede de preparation et medicament les contenant
BE860709A (fr) Nouveaux derives substitues de 0-phenylenediamine, leur procede de preparation et medicament les contenant
BE825245A (fr) Nouvelles 2-amino-6-dialkylaminodihydropyridines leur procede de preparation et medicament les contenant
BE861137A (fr) Ortho-aminoacetophenones utiles comme medicaments et procede pour leur preparation
BE845856A (fr) Sulfoximides substitues, procede pour leur production et medicaments contenant ces composes
BE843341A (fr) Nouvelles penicillines, leur procede de preparation et medicament les contenant
FR2338250A1 (fr) Mono-insuline, procede pour la preparer et medicaments la contenant
FR2348924A1 (fr) Nouvelles carbonylpiperazinylquinazolines azoliques,leur procede de preparation et medicament les contenant
FR2346352A1 (fr) Nouvelles triazinobenzodiazepines, leur procede de preparation et medicament les contenant
BE846397A (fr) Nouvelles 2,4-diamino-5-benzyl-pyrimidines, procede pour leur preparation et medicaments contenant ces composes

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: LUDWIG MERCKLE K.G. CHEM. PHARM. FABRIK

Effective date: 19920531