BE854683A - Benzamides n-acyle substitues, procede pour leur preparation et medicament contenant de tels benzamides - Google Patents
Benzamides n-acyle substitues, procede pour leur preparation et medicament contenant de tels benzamidesInfo
- Publication number
- BE854683A BE854683A BE177612A BE177612A BE854683A BE 854683 A BE854683 A BE 854683A BE 177612 A BE177612 A BE 177612A BE 177612 A BE177612 A BE 177612A BE 854683 A BE854683 A BE 854683A
- Authority
- BE
- Belgium
- Prior art keywords
- benzamides
- acyl
- substitute
- preparation
- product containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2623228A DE2623228C3 (de) | 1976-05-24 | 1976-05-24 | N-Acyl-substituierte Benzamide, Verfahren zu ihrer Herstellung und Arzneimittel, enthaltend solche Benzamide |
Publications (1)
Publication Number | Publication Date |
---|---|
BE854683A true BE854683A (fr) | 1977-11-16 |
Family
ID=5978871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE177612A BE854683A (fr) | 1976-05-24 | 1977-05-16 | Benzamides n-acyle substitues, procede pour leur preparation et medicament contenant de tels benzamides |
Country Status (9)
Country | Link |
---|---|
US (1) | US4146637A (fr) |
AT (1) | AT348990B (fr) |
BE (1) | BE854683A (fr) |
CA (1) | CA1091247A (fr) |
CH (1) | CH633259A5 (fr) |
DE (1) | DE2623228C3 (fr) |
FR (1) | FR2352791A1 (fr) |
GB (1) | GB1555723A (fr) |
NL (1) | NL187437C (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10647661B2 (en) | 2017-07-11 | 2020-05-12 | Vertex Pharmaceuticals Incorporated | Carboxamides as modulators of sodium channels |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2730174C2 (de) * | 1977-07-04 | 1981-12-10 | Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren | Aminobenzoesäurederivate und Arzneimittel enthaltend solche Aminobenzoesäurederivate |
US4251263A (en) * | 1979-09-04 | 1981-02-17 | Stauffer Chemical Company | N-substituted, 2-phenoxynicotinamide compounds and the herbicidal use thereof |
ZA86171B (en) * | 1985-01-16 | 1986-08-27 | Hoffmann La Roche | Polycyclic salts |
US6028111A (en) * | 1996-03-08 | 2000-02-22 | Oxigene, Inc. | Compositions and use of benzamides and nicotinamides as anti-inflammatory agents |
US6100299A (en) * | 1996-03-08 | 2000-08-08 | Oxigene, Inc. | N-acetyl 3-chloroprocainamide, acid addition salts thereof, and methods of use |
JP3933244B2 (ja) * | 1997-04-04 | 2007-06-20 | 株式会社資生堂 | アルキレンジアミン誘導体及び抗潰瘍剤、抗菌剤 |
SE9901875D0 (sv) | 1999-05-25 | 1999-05-25 | Astra Pharma Prod | Novel compounds |
ES2293980T3 (es) * | 2000-01-13 | 2008-04-01 | Amgen Inc. | Agentes antibacterianos. |
US20060235035A1 (en) * | 2002-04-09 | 2006-10-19 | 7Tm Pharma A/S | Novel methoxybenzamibe compounds for use in mch receptor related disorders |
US7351719B2 (en) * | 2002-10-31 | 2008-04-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds |
WO2004048319A1 (fr) * | 2002-11-25 | 2004-06-10 | 7Tm Pharma A/S | Nouveaux composes de benzamide destines a etre utilises dans des troubles associes au recepteur de mch |
US20090238763A1 (en) * | 2006-07-09 | 2009-09-24 | Chongxi Yu | High penetration compositions and uses thereof |
US20090221703A1 (en) | 2006-07-09 | 2009-09-03 | Chongxi Yu | High penetration composition and uses thereof |
WO2008036540A2 (fr) | 2006-09-20 | 2008-03-27 | Boehringer Ingelheim International Gmbh | Inhibiteurs de la rho-kinase |
US8455513B2 (en) | 2007-01-10 | 2013-06-04 | Aerie Pharmaceuticals, Inc. | 6-aminoisoquinoline compounds |
DK2170826T3 (da) * | 2007-06-04 | 2022-07-11 | Techfields Inc | Nsaia-pro-lægemidler med meget høje hud- og membranpenetrationshastigheder og deres nye medicinske anvendelser |
US8455514B2 (en) * | 2008-01-17 | 2013-06-04 | Aerie Pharmaceuticals, Inc. | 6-and 7-amino isoquinoline compounds and methods for making and using the same |
US8450344B2 (en) | 2008-07-25 | 2013-05-28 | Aerie Pharmaceuticals, Inc. | Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds |
CN102307857A (zh) | 2008-12-04 | 2012-01-04 | 于崇曦 | 高穿透性组合物及其它们的应用 |
EP3354643B1 (fr) | 2009-05-01 | 2020-10-28 | Aerie Pharmaceuticals, Inc. | Inhibiteurs à double mécanisme pour le traitement d'une maladie |
ES2942898T3 (es) | 2013-03-15 | 2023-06-07 | Aerie Pharmaceuticals Inc | Compuesto para uso en el tratamiento de trastornos oculares |
EP3101006A1 (fr) * | 2015-06-05 | 2016-12-07 | Lead Pharma Cel Models IP B.V. | Modulateurs de gamma ror (rory) |
EP3376870B1 (fr) | 2015-11-17 | 2021-08-11 | Aerie Pharmaceuticals, Inc. | Procédé de préparation d'inhibiteurs de kinase et de leurs intermédiaires |
US9643927B1 (en) | 2015-11-17 | 2017-05-09 | Aerie Pharmaceuticals, Inc. | Process for the preparation of kinase inhibitors and intermediates thereof |
KR102568082B1 (ko) | 2016-08-31 | 2023-08-17 | 에어리 파마슈티컬즈, 인코포레이티드 | 안과용 조성물 |
US10858339B2 (en) | 2017-03-31 | 2020-12-08 | Aerie Pharmaceuticals, Inc. | Aryl cyclopropyl-amino-isoquinolinyl amide compounds |
CA3112391A1 (fr) | 2018-09-14 | 2020-03-19 | Aerie Pharmaceuticals, Inc. | Composes d'amide aryl cyclopropyl-amino-isoquinolinyl |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR8120M (fr) * | 1968-12-26 | 1970-08-03 | ||
US3898278A (en) * | 1973-04-02 | 1975-08-05 | Menarini Sas | Substituted N-phenylbenzamides |
GB1438612A (en) * | 1974-02-08 | 1976-06-09 | Biorex Laboratories Ltd | Glycyrrhetinic acid derivatives |
-
1976
- 1976-05-24 DE DE2623228A patent/DE2623228C3/de not_active Expired
-
1977
- 1977-05-09 CH CH575477A patent/CH633259A5/de not_active IP Right Cessation
- 1977-05-16 BE BE177612A patent/BE854683A/fr not_active IP Right Cessation
- 1977-05-16 AT AT348877A patent/AT348990B/de not_active IP Right Cessation
- 1977-05-20 GB GB21342/77A patent/GB1555723A/en not_active Expired
- 1977-05-23 NL NLAANVRAGE7705630,A patent/NL187437C/xx not_active IP Right Cessation
- 1977-05-23 FR FR7715663A patent/FR2352791A1/fr active Granted
- 1977-05-23 US US05/799,166 patent/US4146637A/en not_active Expired - Lifetime
- 1977-05-24 CA CA278,971A patent/CA1091247A/fr not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10647661B2 (en) | 2017-07-11 | 2020-05-12 | Vertex Pharmaceuticals Incorporated | Carboxamides as modulators of sodium channels |
US11603351B2 (en) | 2017-07-11 | 2023-03-14 | Vertex Pharmaceuticals Incorporated | Carboxamides as modulators of sodium channels |
Also Published As
Publication number | Publication date |
---|---|
CH633259A5 (de) | 1982-11-30 |
US4146637A (en) | 1979-03-27 |
NL187437B (nl) | 1991-05-01 |
NL187437C (nl) | 1991-10-01 |
FR2352791B1 (fr) | 1979-03-09 |
ATA348877A (de) | 1978-08-15 |
NL7705630A (nl) | 1977-11-28 |
DE2623228A1 (de) | 1977-12-01 |
GB1555723A (en) | 1979-11-14 |
DE2623228C3 (de) | 1981-09-10 |
FR2352791A1 (fr) | 1977-12-23 |
AT348990B (de) | 1979-03-12 |
CA1091247A (fr) | 1980-12-09 |
DE2623228B2 (fr) | 1979-06-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: LUDWIG MERCKLE K.G. CHEM. PHARM. FABRIK Effective date: 19920531 |