BE854102A - Derives de desamination de l'inhibiteur de trypsinekallikreine, procede pour leur production et leur application comme medicament - Google Patents

Derives de desamination de l'inhibiteur de trypsinekallikreine, procede pour leur production et leur application comme medicament

Info

Publication number
BE854102A
BE854102A BE177127A BE177127A BE854102A BE 854102 A BE854102 A BE 854102A BE 177127 A BE177127 A BE 177127A BE 177127 A BE177127 A BE 177127A BE 854102 A BE854102 A BE 854102A
Authority
BE
Belgium
Prior art keywords
trypsinekallikrein
desamination
inhibitor
derivatives
production
Prior art date
Application number
BE177127A
Other languages
English (en)
French (fr)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BE854102A publication Critical patent/BE854102A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C07K14/8117—Bovine/basic pancreatic trypsin inhibitor (BPTI, aprotinin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BE177127A 1976-04-30 1977-04-29 Derives de desamination de l'inhibiteur de trypsinekallikreine, procede pour leur production et leur application comme medicament BE854102A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762619246 DE2619246A1 (de) 1976-04-30 1976-04-30 Desamino-derivate des kallikrein- trypsin-inhibitors, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
BE854102A true BE854102A (fr) 1977-10-31

Family

ID=5976820

Family Applications (1)

Application Number Title Priority Date Filing Date
BE177127A BE854102A (fr) 1976-04-30 1977-04-29 Derives de desamination de l'inhibiteur de trypsinekallikreine, procede pour leur production et leur application comme medicament

Country Status (11)

Country Link
US (1) US4118481A (enExample)
JP (1) JPS52134009A (enExample)
AT (1) AT361118B (enExample)
BE (1) BE854102A (enExample)
CH (1) CH635514A5 (enExample)
DE (1) DE2619246A1 (enExample)
DK (1) DK188077A (enExample)
FR (1) FR2349598A1 (enExample)
GB (1) GB1533358A (enExample)
NL (1) NL7704690A (enExample)
SE (1) SE442301B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748294A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2748295A1 (de) * 1977-10-27 1979-05-03 Bayer Ag Neue derivate des bpti
US4997537A (en) * 1986-10-21 1991-03-05 Northeastern University High performance microcapillary gel electrophoresis
US5665216A (en) * 1986-10-21 1997-09-09 Northeastern University Capillary column for high performance electrophoretic separation and detection of SDS proteins and system and using the same
ATE275583T1 (de) * 1994-01-11 2004-09-15 Dyax Corp KALLIKREINHEMMENDE ßKUNITZ-DOMÄNEß-PROTEINE UND DERIVATEN DAVON
ES2375561T3 (es) * 1994-01-11 2012-03-02 Dyax Corporation Inhibidores de la plasmina humana derivados de dominios kunitz y �?cidos nucleicos que codifican los mismos.
US6057287A (en) * 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
US20040054082A1 (en) * 2001-12-03 2004-03-18 Bank David H Toughened polymer blends with improved surface properties
ES2528254T3 (es) 2002-06-07 2015-02-05 Dyax Corp. Polipéptidos de dominio Kunitz modificado y su uso para reducir la isquemia o el inicio de una respuesta inflamatoria sistémica asociada con un procedimiento quirúrgico
US7153829B2 (en) * 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
DK1542710T3 (da) 2002-08-28 2012-10-15 Dyax Corp Fremgangsmåde til konservering af organer og væv
US7235530B2 (en) * 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US7276480B1 (en) 2005-12-30 2007-10-02 Dyax Corp. Prevention and reduction of blood loss
JP2009529542A (ja) * 2006-03-10 2009-08-20 ダイアックス コーポレーション エカランチドに関する配合物
JP2010536870A (ja) * 2007-08-21 2010-12-02 ジェンザイム・コーポレーション カリクレイン阻害剤を用いた治療
WO2009026539A1 (en) * 2007-08-23 2009-02-26 Genzyme Corporation Treatment with kallikrein inhibitors
WO2010080833A1 (en) * 2009-01-06 2010-07-15 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
HRP20220107T1 (hr) 2010-01-06 2022-04-15 Takeda Pharmaceutical Company Limited Proteini koji vežu kalikrein plazme
KR102107695B1 (ko) 2011-01-06 2020-05-07 다이액스 코포레이션 혈장 칼리크레인 결합 단백질
CA2942713A1 (en) 2014-03-27 2015-10-01 Dyax Corp. Compositions and methods for treatment of diabetic macular edema
EP3387018A1 (en) 2015-12-11 2018-10-17 Dyax Corp. Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack
AU2021209045A1 (en) 2020-01-13 2022-07-28 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating pediatric hereditary angioedema attack

Also Published As

Publication number Publication date
AT361118B (de) 1981-02-25
FR2349598B1 (enExample) 1980-02-22
SE7704928L (sv) 1977-10-31
GB1533358A (en) 1978-11-22
US4118481A (en) 1978-10-03
FR2349598A1 (fr) 1977-11-25
NL7704690A (nl) 1977-11-01
JPS52134009A (en) 1977-11-09
SE442301B (sv) 1985-12-16
CH635514A5 (de) 1983-04-15
DK188077A (da) 1977-10-31
DE2619246A1 (de) 1977-11-10
ATA305477A (de) 1980-07-15

Similar Documents

Publication Publication Date Title
FR2349598A1 (fr) Derives de desamination de l'inhibiteur de trypsine-kallikreine, procede pour leur production et leur application comme medicament
FR2321469A1 (fr) Procede de production d'ethanol a partir de cellulose
RO68441A (ro) Procedeu pentru prepararea unor derivati de eritromicilamina
BE833731A (fr) Derives d'alcool benzylique, procede pour leur preparation et application comme medicament
BE876435A (fr) Derives d'hydantoine, procede pour leur preparation et application de ces composes comme medicaments
LU79294A1 (fr) Procede pour la preparation de nouveaux derives de la morphine et application a titre de medicament
GB2011900A (en) N'-substituted -aminoalkanoyl- -aminoalkanoic acids their use and process for their production as well as pharmaceutical products containing these compounds
MA18832A1 (fr) Nouvelle saponine triterpenique,son procede d'obtention et son emploi comme medicament
BE880153A (fr) Derives de 7-oxo-4-thia-1-aza-bicyclo- (3,2,0) -heptane, procede pour les preparer et leur application comme medicaments
BE858283A (fr) Nouveaux derives de perhydro-aza-heterocycles utiles comme medicaments et procede pour leur preparation
BE828430A (fr) Phenylalcoylamines, leur procede d'obtention et leur application commemedicaments
PT66174A (fr) Procede pour la preparation de derives de ditiole-1,2 et de compositions qu'en contiennent
FR2317924A1 (fr) Procede de production de derives d'ortho-aminobutyrophenone, nouveaux produits ainsi obtenus et leur utilisation comme agents analgesiques et antipsychose
FR2349331A1 (fr) Nouveaux derives de 2,3 dihydro a/4-(3-indolyl) 1-piperidinyl/methyl 1,4-benzodioxin-2-methanol, un procede pour leur preparation et leur application comme medicaments
BE870709A (fr) Derives nouveaux de 7-azabenzimidazol a chaines laterales basiques, procede pour leur preparation et application comme medicaments
BE859120A (fr) Procede pour la preparation de steroides polyhalogenes utiles comme medicaments
BE833807A (fr) Phenoxyalkanecarbonamides d'acides thiazolidinecarboxyliques substitues, procede pour leur preparation et application comme medicament
BE794424A (fr) Nouveaux dibenzocycloheptenes, leur procede d'obtention et leur application comme medicament
FR2344286A1 (fr) Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament
BE861137A (fr) Ortho-aminoacetophenones utiles comme medicaments et procede pour leur preparation
BE866588A (fr) Derives de 2-benzyl-perhydroazepines, procede pour leur preparation et application comme medicaments
BE849013A (fr) Nouveaux diphenylacetamides, leur procede d'obtention et leur emploi comme medicament
BE871961A (fr) Procede ameliore pour la production d'alkylene-glycols
BE863881A (fr) Derives de la coumarine et d'indane-dione, utilisables comme medicament
LU81409A1 (fr) Nouveaux derives de la l-cysteine et leur application comme medicament,ainsi que composes intermediaires utiles pour leur procede de preparation

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BAYER A.G.

Effective date: 19860430