BE851777A - Procede de preparation d'aminoglycosides a substituant 2- hydroxy-w-amino-alkyle sur le groupe 1-amino - Google Patents

Procede de preparation d'aminoglycosides a substituant 2- hydroxy-w-amino-alkyle sur le groupe 1-amino

Info

Publication number
BE851777A
BE851777A BE175220A BE175220A BE851777A BE 851777 A BE851777 A BE 851777A BE 175220 A BE175220 A BE 175220A BE 175220 A BE175220 A BE 175220A BE 851777 A BE851777 A BE 851777A
Authority
BE
Belgium
Prior art keywords
amino
aminoglycosides
hydroxy
preparing
amino group
Prior art date
Application number
BE175220A
Other languages
English (en)
French (fr)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BE851777A publication Critical patent/BE851777A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D265/10—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen atoms directly attached to ring carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BE175220A 1976-02-25 1977-02-24 Procede de preparation d'aminoglycosides a substituant 2- hydroxy-w-amino-alkyle sur le groupe 1-amino BE851777A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7529/76A GB1529243A (en) 1976-02-25 1976-02-25 Process for the preparation of aminoglycoside derivatives and cyclic urethane intermediates for use therein

Publications (1)

Publication Number Publication Date
BE851777A true BE851777A (fr) 1977-08-24

Family

ID=9834870

Family Applications (1)

Application Number Title Priority Date Filing Date
BE175220A BE851777A (fr) 1976-02-25 1977-02-24 Procede de preparation d'aminoglycosides a substituant 2- hydroxy-w-amino-alkyle sur le groupe 1-amino

Country Status (26)

Country Link
US (1) US4107435A (nl)
JP (1) JPS52111545A (nl)
AR (1) AR215616A1 (nl)
AT (1) AT348123B (nl)
BE (1) BE851777A (nl)
CA (1) CA1071624A (nl)
CH (1) CH618706A5 (nl)
CS (2) CS195714B2 (nl)
DD (2) DD130150A5 (nl)
DE (1) DE2708008C3 (nl)
DK (1) DK82177A (nl)
EG (1) EG12650A (nl)
ES (1) ES456304A1 (nl)
FI (1) FI770568A (nl)
FR (2) FR2351109A1 (nl)
GB (1) GB1529243A (nl)
GR (1) GR66424B (nl)
HU (1) HU179565B (nl)
IE (1) IE44885B1 (nl)
LU (1) LU76829A1 (nl)
NL (2) NL166265C (nl)
PL (2) PL102193B1 (nl)
PT (1) PT66229B (nl)
RO (1) RO76081A (nl)
SE (1) SE7702066L (nl)
SU (1) SU659092A3 (nl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5461151A (en) * 1977-10-25 1979-05-17 Shionogi & Co Ltd Novel aminoglycoside derivative
US4327087A (en) * 1978-01-16 1982-04-27 Schering Corporation Stabilized Netilmicin formulations
US4223022A (en) * 1978-01-16 1980-09-16 Schering Corporation Stabilized aminoglycoside antibiotic formulations
JPS5538345A (en) * 1978-09-11 1980-03-17 Shionogi & Co Ltd Novel aminoglycoside derivative
US4226980A (en) * 1978-12-07 1980-10-07 Abbott Laboratories Novel derivatives of fortimicin B and process for preparing same
DE2924659A1 (de) * 1979-06-19 1981-01-22 Bayer Ag Pseudotrisaccharide, ihre herstellung und verwendung als arzneimittel
DE3000841A1 (de) * 1980-01-11 1981-07-16 Bayer Ag, 5090 Leverkusen Isolierung und reinigung von aminoglycosid-antibiotiaka
DE3101376A1 (de) * 1981-01-17 1982-09-02 Bayer Ag, 5090 Leverkusen Sisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4427663A (en) 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
WO2009117036A2 (en) * 2007-12-21 2009-09-24 Massachusetts Institute Of Technology Bioactive molecules from co-cultivation of microbes
WO2018005964A1 (en) * 2016-07-01 2018-01-04 Wake Forest University Health Sciences Modified carbohydrates, compositions comprising the same, and methods of making and using the same
US10766970B2 (en) 2016-07-01 2020-09-08 Wake Forest University Health Sciences Modified carbohydrates, compositions comprising the same, and methods of making and using the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2399118A (en) * 1942-02-13 1946-04-23 Mallinckrodt Chemical Works 2-oxazolidone compounds and method for preparing the same
DE1593321A1 (de) * 1962-04-03 1970-04-02 Rit Rech Ind Therapeut Verfahren zur Herstellung von niederen N-Alkylderivaten basischer Antibiotica

Also Published As

Publication number Publication date
DE2708008B2 (de) 1981-07-02
PT66229B (en) 1978-07-17
LU76829A1 (nl) 1978-10-18
RO76081A (ro) 1981-08-17
FR2351109B1 (nl) 1981-07-24
IE44885B1 (en) 1982-05-05
HU179565B (en) 1982-11-29
DD135200A5 (de) 1979-04-18
EG12650A (en) 1979-06-30
DK82177A (da) 1977-08-26
GR66424B (nl) 1981-03-20
NL166265C (nl) 1981-07-15
AR215616A1 (es) 1979-10-31
NL7701980A (nl) 1977-08-29
ATA116777A (de) 1978-06-15
DE2708008C3 (de) 1982-04-22
IE44885L (en) 1977-08-25
GB1529243A (en) 1978-10-18
DD130150A5 (de) 1978-03-08
AT348123B (de) 1979-01-25
NL166265B (nl) 1981-02-16
FR2351127B1 (nl) 1981-06-12
FR2351109A1 (fr) 1977-12-09
JPS52111545A (en) 1977-09-19
SE7702066L (sv) 1977-08-26
DE2708008A1 (de) 1977-09-01
PL102193B1 (pl) 1979-03-31
PL103737B1 (pl) 1979-07-31
NL7901693A (nl) 1979-07-31
FI770568A (nl) 1977-08-26
CH618706A5 (nl) 1980-08-15
US4107435A (en) 1978-08-15
CS195715B2 (en) 1980-02-29
CS195714B2 (en) 1980-02-29
ES456304A1 (es) 1978-01-16
FR2351127A1 (fr) 1977-12-09
PT66229A (en) 1977-03-01
SU659092A3 (en) 1979-04-25
CA1071624A (en) 1980-02-12

Similar Documents

Publication Publication Date Title
BE835279A (fr) Procede de preparation de polyisocyanates a structure d'isocyandrates
CS193100B2 (en) Process for preparing dyes
FR2342981A1 (fr) Procede de preparation d'hydrogenosilanes
FR2351127A1 (fr) Procede de preparation d'aminoglycosides a substituant 2-hydroxy-o- amino-alkyle sur le groupe 1-amino
BE858576A (fr) Procede de preparation d'ethers
BE853564A (fr) Procede de preparation d'antibiotiques aminoglycosidiques
FR2352772A1 (fr) Procede d'hydrogenation stereoselective de l'a-pinene
FR2347345A1 (fr) Procede de preparation d'alkylthiomethylphenols
PT66743A (en) Process for preparing novel 2-oxy-5-isopropylidene-7-hydroxy-9-substituted-2,6-methano-3,4,5,6-tetrahydro-2h-1-benzoxocins
JPS5368727A (en) Process for preparing sulfate
BE855371A (fr) Procede de preparation de 1,1-difluorethylene
AU513177B2 (en) Preparing amines
HU175611B (hu) Sposob poluchenija 3,5,5-trimetil-geksanoil-ferrocena
PT66206B (en) Process for preparing 2,9-dioxatricyclo/4,3,1,03,7/decanes
JPS5295788A (en) Photosensitive polymer and process for preparing the same
BE852059A (fr) Procede de preparation de molybdene 99
AU509447B2 (en) Cyclosulphones for electrodeposition baths
YU298677A (en) Process for preparing 3,4-dideoxy-kanamycin b
BE859244A (fr) Procede de preparation de certains benzotrichlorures chlores sur le noyau
HU174318B (hu) Sposob poluchenija 2,4-diamino-5-/3',4',5'-trimetoksi-benzil/-pirimidina
BE860268A (fr) Procede de preparation d'alkylphenols
JPS52136137A (en) Process for preparing 2*66dii terttbutyl phenol
JPS5340729A (en) Process for preparing 2*66 diiterttbutyl phenol
FR2344564A2 (fr) Procede de preparation de 2,5-dioxo-1,2-oxa-phospholannes
BE844901A (fr) Procede de preparation de l'echinenone