BE850104A - 1-(alcanoyl aminosubstitue)-2-(dibenzoxazepine-10-carbonyl) hydrazines - Google Patents

1-(alcanoyl aminosubstitue)-2-(dibenzoxazepine-10-carbonyl) hydrazines

Info

Publication number
BE850104A
BE850104A BE173851A BE173851A BE850104A BE 850104 A BE850104 A BE 850104A BE 173851 A BE173851 A BE 173851A BE 173851 A BE173851 A BE 173851A BE 850104 A BE850104 A BE 850104A
Authority
BE
Belgium
Prior art keywords
aminosubstitute
alcanoyl
dibenzoxazepine
hydrazines
carbonyl
Prior art date
Application number
BE173851A
Other languages
English (en)
French (fr)
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of BE850104A publication Critical patent/BE850104A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D267/20—[b, f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BE173851A 1976-01-05 1977-01-05 1-(alcanoyl aminosubstitue)-2-(dibenzoxazepine-10-carbonyl) hydrazines BE850104A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/646,686 US4045442A (en) 1976-01-05 1976-01-05 1-(Substituted amino)alkanoyl-2-(dibenzoxazepine-10-carbonyl)hydrazines and derivatives thereof

Publications (1)

Publication Number Publication Date
BE850104A true BE850104A (fr) 1977-07-05

Family

ID=24594058

Family Applications (1)

Application Number Title Priority Date Filing Date
BE173851A BE850104A (fr) 1976-01-05 1977-01-05 1-(alcanoyl aminosubstitue)-2-(dibenzoxazepine-10-carbonyl) hydrazines

Country Status (17)

Country Link
US (2) US4045442A (da)
JP (1) JPS6051474B2 (da)
AT (1) AT354453B (da)
AU (1) AU506737B2 (da)
BE (1) BE850104A (da)
CA (1) CA1077476A (da)
CH (1) CH632502A5 (da)
DE (1) DE2700091A1 (da)
DK (1) DK2677A (da)
ES (1) ES454780A1 (da)
FR (1) FR2337130A1 (da)
GB (1) GB1508117A (da)
IE (1) IE44330B1 (da)
NL (1) NL7700033A (da)
NZ (1) NZ182987A (da)
SE (1) SE424992B (da)
ZA (1) ZA7731B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4290953A (en) * 1978-12-06 1981-09-22 Chugai Seiyaku Kabushiki Kaisha Benzoxazepine derivatives and process for preparing the same

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4170593A (en) * 1976-01-05 1979-10-09 G. D. Searle & Co. 1-(Substituted amino)alkanoyl-2-(dibenzoxapine-10-carbonyl)hydrazines and derivatives thereof
US4559336A (en) * 1985-02-25 1985-12-17 G.D. Searle & Co. 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(sulfinyl- and sulfonyl-containing acyl)hydrazides
US4559337A (en) * 1985-02-25 1985-12-17 G.D. Searle & Co. 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(alkoxy-containing acyl)hydrazides
US4681939A (en) * 1985-08-29 1987-07-21 G. D. Searle & Co. 8-chlorodibenz[b,f][1,4]oxazepine-10-(11H)-carboxylic acid, 2-[(phenylthio)alkanoyl]hydrazides
US4704386A (en) * 1985-08-29 1987-11-03 G. D. Searle & Co. 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[(phenylsulfinyl-, and phenylsulfonyl)alkanoyl]hydrazides
WO1992019617A2 (en) * 1991-05-03 1992-11-12 G.D. Searle & Co. Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5378840A (en) * 1992-04-16 1995-01-03 G. D. Searle & Co. Substituted dibenzoxazepine compounds
US5180720A (en) * 1991-05-03 1993-01-19 G. D. Searle & Co. 2- and 3-alkoxy or hydroxy-8-substituted-dibenz[b,f]-[1,4]oxazepine-10(11H)-carboxylic acid, substituted hydrazides and methods for treating pain
US5182272A (en) * 1991-05-03 1993-01-26 G. D. Searle & Co. 8-substituted-dibenz[b,f][1,4]oxazepine-10(11)-carboxylic acid, substituted hydrazides, pharmaceutical compositions, and methods for treating pain
US5212169A (en) * 1991-10-31 1993-05-18 G. D. Searle & Co. Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain
CA2118688A1 (en) * 1991-11-05 1993-05-13 Timothy J. Hagen Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
AU3143593A (en) * 1991-12-20 1993-07-28 G.D. Searle & Co. Substituted dibenzoxazepines or dibenzothiazepines and their use as prostaglandin E2 antagonists
US5304644A (en) * 1992-04-15 1994-04-19 G. D. Searle & Co. 1-,2-,3-,4-,5-,6-,7-,8- and/or 9 substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain
US5449673A (en) * 1992-08-13 1995-09-12 G. D. Searle & Co. 10,11-dihydro-10-(3-substituted-1-oxo-2-propyl, propenyl or propynyl)dibenz[b,f][1,4] oxazepine prostaglandin antagonists
US5395932A (en) * 1993-04-30 1995-03-07 G. D. Searle & Co. 2,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5354746A (en) * 1993-06-01 1994-10-11 G. D. Searle & Co. Squaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5461047A (en) * 1993-06-16 1995-10-24 G. D. Searle & Co. 2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
US5354747A (en) * 1993-06-16 1994-10-11 G. D. Searle & Co. 2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
US5420270A (en) * 1993-10-07 1995-05-30 G. D. Searle & Co. Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5424424A (en) * 1993-10-07 1995-06-13 G. D. Searle & Co. Tartaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5488046A (en) * 1993-11-03 1996-01-30 G. D. Searle & Co. Carbamic acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5449675A (en) * 1994-06-09 1995-09-12 G. D. Searle & Co. Substituted dibenzoxazepine and dibenzthiazepine urea compounds, pharmaceutical compositions and methods of use
US5441950A (en) * 1994-06-09 1995-08-15 G. D. Searle & Co. Substituted dibenzoxazepine and dibenzthiazepine carbamate compounds, pharmaceutical compositions and methods of use

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1138055B (de) * 1957-12-20 1962-10-18 Geigy Ag J R Verfahren zur Herstellung von N-substituierten Azepinen und deren Salzen
DE1136706B (de) * 1958-05-30 1962-09-20 Cilag Chemie Verfahren zur Herstellung von basisch substituierten, schwefelhaltigen 1-Aza-[2, 3:5, 6]-dibenzocycloheptadien-derivaten und deren Salzen
DE1145620B (de) * 1958-07-23 1963-03-21 Geigy Ag J R Verfahren zur Herstellung von basisch substituierten Azepinderivaten und deren Salzen
GB1206332A (en) * 1967-04-08 1970-09-23 Yoshitomi Pharmaceutical Cyclic hydroxamic acid derivatives
US3534019A (en) * 1967-10-30 1970-10-13 Searle & Co Dibenzoxazepine - n - carboxylic acid hydrazides and related compounds
US3953469A (en) * 1968-04-24 1976-04-27 E. R. Squibb & Sons, Inc. Benzoxozepine carboxamides and derivatives thereof
US3624104A (en) * 1969-10-27 1971-11-30 Searle & Co Aralkanoyl derivatives of dibenzoxazepine-n-carboxylic acid hydrazides
US3718665A (en) * 1970-09-30 1973-02-27 Squibb & Sons Inc Azabicyclo-(n)-alkylene-5,11-dihydrodibenzoxa(or thia)zepines
CA981666A (en) * 1970-11-24 1976-01-13 E.R. Squibb And Sons 5,11-dihydrodibenzoxa(or thia)zepine derivatives
US3917649A (en) * 1971-03-23 1975-11-04 Searle & Co Dibenzoxazepine N-carboxylic acid hydrazides and derivatives
US4012393A (en) * 1976-03-22 1977-03-15 G. D. Searle & Co. 2-[5-(CYCLIC AMINO) ETHYL-10,11-DIHYDRO-5H-dibenzo[a,d]-cyclohepten-5- yl]-5

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4290953A (en) * 1978-12-06 1981-09-22 Chugai Seiyaku Kabushiki Kaisha Benzoxazepine derivatives and process for preparing the same

Also Published As

Publication number Publication date
IE44330B1 (en) 1981-10-21
AT354453B (de) 1979-01-10
FR2337130A1 (fr) 1977-07-29
ES454780A1 (es) 1978-01-01
DE2700091A1 (de) 1977-07-14
FR2337130B1 (da) 1980-04-18
GB1508117A (en) 1978-04-19
NL7700033A (nl) 1977-07-07
ATA1577A (de) 1979-06-15
AU506737B2 (en) 1980-01-24
DE2700091C2 (da) 1989-03-02
DK2677A (da) 1977-07-06
CA1077476A (en) 1980-05-13
JPS5285183A (en) 1977-07-15
JPS6051474B2 (ja) 1985-11-14
ZA7731B (en) 1978-02-22
IE44330L (en) 1977-07-05
NZ182987A (en) 1979-07-11
US4045442A (en) 1977-08-30
AU2102877A (en) 1978-07-13
SE424992B (sv) 1982-08-23
SE7700051L (sv) 1977-07-06
CH632502A5 (de) 1982-10-15
US4125532A (en) 1978-11-14

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: G.D. SEARLE & CO.

Effective date: 19850105