BE836954A - Nouveaux derives du tryptophane a activite nerveuse centrale renforcee - Google Patents
Nouveaux derives du tryptophane a activite nerveuse centrale renforceeInfo
- Publication number
- BE836954A BE836954A BE163017A BE163017A BE836954A BE 836954 A BE836954 A BE 836954A BE 163017 A BE163017 A BE 163017A BE 163017 A BE163017 A BE 163017A BE 836954 A BE836954 A BE 836954A
- Authority
- BE
- Belgium
- Prior art keywords
- central nervous
- nervous activity
- tryptophan derivatives
- reinforced central
- new
- Prior art date
Links
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical class C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/003—Compounds containing elements of Groups 2 or 12 of the Periodic Table without C-Metal linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7442505A FR2295746A1 (fr) | 1974-12-23 | 1974-12-23 | Nouveaux derives du tryptophane a activite nerveuse centrale renforcee |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE836954A true BE836954A (fr) | 1976-04-16 |
Family
ID=9146520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE163017A BE836954A (fr) | 1974-12-23 | 1975-12-22 | Nouveaux derives du tryptophane a activite nerveuse centrale renforcee |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4299838A (de) |
| BE (1) | BE836954A (de) |
| DE (1) | DE2557497C2 (de) |
| ES (1) | ES443766A1 (de) |
| FR (1) | FR2295746A1 (de) |
| GB (1) | GB1529340A (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04506967A (ja) * | 1989-07-27 | 1992-12-03 | ジー．ディー．サール アンド カンパニー | 高血圧症治療用腎選択性生成物 |
| US5939076A (en) * | 1997-11-12 | 1999-08-17 | Allocca Techical, Inc. | Composition and method for treating or alleviating migraine headaches |
| WO1999052539A1 (en) | 1998-04-10 | 1999-10-21 | Mayo Foundation For Medical Education And Research | Neo-tryptophan |
| US7087575B2 (en) * | 2002-07-18 | 2006-08-08 | Mayo Foundation For Medical Education And Research | Treating the effect of nicotine |
| PT1549333E (pt) | 2002-09-20 | 2012-01-03 | Univ Pennsylvania | Análogos de compstatina com actividade melhorada |
| US7399324B2 (en) * | 2004-01-29 | 2008-07-15 | Camovision Of Georgia, Llc | Active agent delivery device |
| US8168584B2 (en) | 2005-10-08 | 2012-05-01 | Potentia Pharmaceuticals, Inc. | Methods of treating age-related macular degeneration by compstatin and analogs thereof |
| PL1951279T3 (pl) | 2005-10-08 | 2017-12-29 | Apellis Pharmaceuticals, Inc. | Kompstatyna i jej analogi w zaburzeniach oczu |
| PT1960422E (pt) * | 2005-11-28 | 2012-08-16 | Univ Pennsylvania | Análogos de compstatina potentes |
| WO2007100718A2 (en) * | 2006-02-24 | 2007-09-07 | Denise Barbut | Neurotensin receptor agonists and opioid receptor agonists |
| WO2007114948A2 (en) * | 2006-04-04 | 2007-10-11 | The Brigham And Women's Hospital, Inc. | Methods and compositions for inhibiting cell death |
| US8580735B2 (en) | 2007-02-05 | 2013-11-12 | Apellis Pharmaceuticals, Inc. | Local complement inhibition for treatment of complement-mediated disorders |
| JP5882890B2 (ja) | 2009-05-01 | 2016-03-09 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | ペプチド骨格およびｃ末端改変を持つ改変したコンプスタチン |
| CA2813049A1 (en) | 2010-09-23 | 2012-03-29 | The Trustees Of The University Of Pennsylvania | Modified compstatin with improved stability and binding properties |
| EP4105224A1 (de) | 2011-05-11 | 2022-12-21 | Apellis Pharmaceuticals, Inc. | Langwirkende compstatin-analoga und verwendungen davon |
| AU2012272706B2 (en) | 2011-06-22 | 2017-07-06 | Apellis Pharmaceuticals, Inc. | Methods of treating chronic disorders with complement inhibitors |
| ES2766755T3 (es) | 2011-09-07 | 2020-06-15 | Univ Pennsylvania | Análogos de compstatina con propiedades farmacocinéticas mejoradas |
| EP3660033B9 (de) | 2012-11-15 | 2022-06-22 | Apellis Pharmaceuticals, Inc. | Langwirkende compstatin-analoga sowie verwandte zusammensetzungen und verfahren |
| US10308687B2 (en) | 2013-03-15 | 2019-06-04 | Apellis Pharmaceuticals, Inc. | Cell-penetrating compstatin analogs and uses thereof |
| US10213476B2 (en) | 2014-03-17 | 2019-02-26 | The Trustees Of The University Of Pennsylvania | Compstatin analogs with improved potency and pharmacokinetic properties |
| BR112018006810A2 (pt) | 2015-10-07 | 2018-10-23 | Apellis Pharmaceuticals Inc | regimes de dosagem |
| CN110831544B (zh) | 2017-04-07 | 2022-11-18 | 阿佩利斯制药有限公司 | 长效坎普他汀类似物、其组合物的给药方案及其医药用途 |
| RU2020136249A (ru) | 2018-04-06 | 2022-05-06 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Аналоги компстатина с увеличенной растворимостью и улучшенными фармакокинетическими свойствами |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2865928A (en) * | 1956-08-03 | 1958-12-23 | Du Pont | Resolution of n-acyl-dl-tryptophans |
| GB873777A (en) * | 1959-01-26 | 1961-07-26 | Upjohn Co | 5-hydroxy-ª--alkyltryptophans |
| BE791909A (fr) * | 1971-11-24 | 1973-05-24 | Beecham Group Ltd | Compositions pharmaceutiques contenant du lithium et du tryptophane |
-
1974
- 1974-12-23 FR FR7442505A patent/FR2295746A1/fr active Granted
-
1975
- 1975-12-15 GB GB51324/75A patent/GB1529340A/en not_active Expired
- 1975-12-19 DE DE2557497A patent/DE2557497C2/de not_active Expired
- 1975-12-22 BE BE163017A patent/BE836954A/xx not_active IP Right Cessation
- 1975-12-22 ES ES443766A patent/ES443766A1/es not_active Expired
-
1978
- 1978-02-17 US US05/878,811 patent/US4299838A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US4299838A (en) | 1981-11-10 |
| FR2295746A1 (fr) | 1976-07-23 |
| DE2557497A1 (de) | 1976-06-24 |
| ES443766A1 (es) | 1977-04-16 |
| GB1529340A (en) | 1978-10-18 |
| DE2557497C2 (de) | 1983-11-03 |
| FR2295746B1 (de) | 1978-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: LES LABORATOIRES MERAM Effective date: 19881231 |