BE836954A - Nouveaux derives du tryptophane a activite nerveuse centrale renforcee - Google Patents
Nouveaux derives du tryptophane a activite nerveuse centrale renforceeInfo
- Publication number
- BE836954A BE836954A BE163017A BE163017A BE836954A BE 836954 A BE836954 A BE 836954A BE 163017 A BE163017 A BE 163017A BE 163017 A BE163017 A BE 163017A BE 836954 A BE836954 A BE 836954A
- Authority
- BE
- Belgium
- Prior art keywords
- central nervous
- nervous activity
- tryptophan derivatives
- reinforced central
- new
- Prior art date
Links
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical class C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/003—Compounds containing elements of Groups 2 or 12 of the Periodic Table without C-Metal linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7442505A FR2295746A1 (fr) | 1974-12-23 | 1974-12-23 | Nouveaux derives du tryptophane a activite nerveuse centrale renforcee |
Publications (1)
Publication Number | Publication Date |
---|---|
BE836954A true BE836954A (fr) | 1976-04-16 |
Family
ID=9146520
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE163017A BE836954A (fr) | 1974-12-23 | 1975-12-22 | Nouveaux derives du tryptophane a activite nerveuse centrale renforcee |
Country Status (6)
Country | Link |
---|---|
US (1) | US4299838A (xx) |
BE (1) | BE836954A (xx) |
DE (1) | DE2557497C2 (xx) |
ES (1) | ES443766A1 (xx) |
FR (1) | FR2295746A1 (xx) |
GB (1) | GB1529340A (xx) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0484437A4 (en) * | 1989-07-27 | 1994-06-01 | Searle & Co | Renal-selective prodrugs for the treatment of hypertension |
US5939076A (en) * | 1997-11-12 | 1999-08-17 | Allocca Techical, Inc. | Composition and method for treating or alleviating migraine headaches |
WO1999052539A1 (en) * | 1998-04-10 | 1999-10-21 | Mayo Foundation For Medical Education And Research | Neo-tryptophan |
US7087575B2 (en) * | 2002-07-18 | 2006-08-08 | Mayo Foundation For Medical Education And Research | Treating the effect of nicotine |
ES2373649T3 (es) | 2002-09-20 | 2012-02-07 | The Trustees Of The University Of Pennsylvania | Análogos de compstatina con actividad mejorada. |
US7399324B2 (en) * | 2004-01-29 | 2008-07-15 | Camovision Of Georgia, Llc | Active agent delivery device |
US8168584B2 (en) | 2005-10-08 | 2012-05-01 | Potentia Pharmaceuticals, Inc. | Methods of treating age-related macular degeneration by compstatin and analogs thereof |
CN101325963B (zh) | 2005-10-08 | 2016-01-27 | 博泰迪亚制药公司 | 用于眼部病症的补体抑制素和其类似物 |
EP2377877B1 (en) | 2005-11-28 | 2018-03-28 | The Trustees Of The University Of Pennsylvania | Potent compstatin analogs |
US7671025B2 (en) * | 2006-02-24 | 2010-03-02 | Sarentis Therapeutics, Inc. | Neurotensin receptor agonists and opioid receptor agonists |
WO2007114948A2 (en) * | 2006-04-04 | 2007-10-11 | The Brigham And Women's Hospital, Inc. | Methods and compositions for inhibiting cell death |
ES2545775T3 (es) | 2007-02-05 | 2015-09-15 | Apellis Pharmaceuticals, Inc. | Análogos de compstatina para uso en el tratamiento de afecciones inflamatorias del sistema respiratorio |
CN102458438A (zh) | 2009-05-01 | 2012-05-16 | 宾夕法尼亚州大学理事会 | 具有肽骨架和c-末端修饰的经修饰补体抑素 |
WO2012040259A2 (en) | 2010-09-23 | 2012-03-29 | The Trustees Of The University Of Pennsylvania | Modified compstatin with improved stability and binding properties |
CN107050422B (zh) | 2011-05-11 | 2021-11-09 | 阿佩利斯制药公司 | 细胞反应性的、长效的或靶向的坎普他汀类似物及其用途 |
MX363606B (es) | 2011-06-22 | 2019-03-28 | Apellis Pharmaceuticals Inc | Uso de inhibidores del complemento en trastornos crónicos. |
EP2753636B1 (en) | 2011-09-07 | 2019-10-23 | The Trustees Of The University Of Pennsylvania | Compstatin analogs with improved pharmacokinetic properties |
SI3660033T1 (sl) | 2012-11-15 | 2021-09-30 | Apellis Pharmaceuticals, Inc. | Analogi kompstatina z dolgotrajnim delovanjem in sorodni sestavki in postopki |
WO2014152391A1 (en) | 2013-03-15 | 2014-09-25 | Apellis Pharmaceuticals, Inc. | Cell-penetrating compstatin analogs and uses thereof |
US10213476B2 (en) | 2014-03-17 | 2019-02-26 | The Trustees Of The University Of Pennsylvania | Compstatin analogs with improved potency and pharmacokinetic properties |
RU2770099C2 (ru) | 2015-10-07 | 2022-04-14 | Апеллис Фармасьютикалс, Инк. | Схемы введения |
US11040107B2 (en) | 2017-04-07 | 2021-06-22 | Apellis Pharmaceuticals, Inc. | Dosing regimens and related compositions and methods |
AU2019247467B2 (en) | 2018-04-06 | 2023-01-19 | The Trustees Of The University Of Pennsylvania | Compstatin analogs with increased solubility and improved pharmacokinetic properties |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2865928A (en) * | 1956-08-03 | 1958-12-23 | Du Pont | Resolution of n-acyl-dl-tryptophans |
GB873777A (en) * | 1959-01-26 | 1961-07-26 | Upjohn Co | 5-hydroxy-ª--alkyltryptophans |
BE791909A (fr) * | 1971-11-24 | 1973-05-24 | Beecham Group Ltd | Compositions pharmaceutiques contenant du lithium et du tryptophane |
-
1974
- 1974-12-23 FR FR7442505A patent/FR2295746A1/fr active Granted
-
1975
- 1975-12-15 GB GB51324/75A patent/GB1529340A/en not_active Expired
- 1975-12-19 DE DE2557497A patent/DE2557497C2/de not_active Expired
- 1975-12-22 BE BE163017A patent/BE836954A/xx not_active IP Right Cessation
- 1975-12-22 ES ES443766A patent/ES443766A1/es not_active Expired
-
1978
- 1978-02-17 US US05/878,811 patent/US4299838A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE2557497A1 (de) | 1976-06-24 |
ES443766A1 (es) | 1977-04-16 |
FR2295746B1 (xx) | 1978-08-18 |
DE2557497C2 (de) | 1983-11-03 |
FR2295746A1 (fr) | 1976-07-23 |
US4299838A (en) | 1981-11-10 |
GB1529340A (en) | 1978-10-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2295746A1 (fr) | Nouveaux derives du tryptophane a activite nerveuse centrale renforcee | |
FR2326181A1 (fr) | Nouveaux derives benzhydrylsulfinyle | |
BE817826A (fr) | Nouveaux derives de la phenylethylamine | |
FR2329270A1 (fr) | Nouveaux composes a activite anti-fertilite | |
BE787941A (fr) | Nouveaux derives d'oxazoline a activite anti-inflammatoire | |
FR2326198A1 (fr) | Nouveaux steroides a activite erythropoietique | |
BE824579A (fr) | Nouveaux amides a activite pharmacologique | |
BE814617A (fr) | Nouveaux derives de phenylethanolamine a activite pharmacoleogique | |
BE821418A (fr) | Nouveaux derives thiazoliques | |
BE819749A (fr) | Nouveaux derives du benzoxoazole utilisables | |
FR2329263A1 (fr) | Derives du naphtalene | |
BE846805A (fr) | Nouveaux steroides a activite erythropoietique | |
BE852457A (fr) | Nouveaux derives 17-spirosultines | |
BE808544A (fr) | Derives du benzimidazole a substitution basique | |
BE795265A (fr) | Nouveaux derives de quinoleine a activite pharmacologique | |
BE825075A (fr) | Nouveaux derives de la 1,2,4-oxdiazoline-5-one a activite fongicide | |
BE816566A (fr) | Nouveaux derives cyclopentaniques | |
BE849388A (fr) | Nouveaux derives de la spermine a activite bacteriostatique | |
BE819283A (fr) | Nouveaux derives du thiazol 5-methanol | |
BE815565A (fr) | Derives du benzimidazole | |
FR2278324A1 (fr) | Nouveaux derives du paracetamol | |
BE820723A (fr) | Nouveaux derives pyridiques | |
BE810400A (fr) | Nouveaux derives caphalosporaniques | |
FR2309218A1 (fr) | Nouveaux derives de benzobicyclononene a activite anorexiante | |
BE817377A (fr) | Nouveaux thiocarbamates a activite herbicide |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: LES LABORATOIRES MERAM Effective date: 19881231 |