BE825653A - Compositions pharmaceutiques antibiotiques contenant le sel de sodium de l'acide 7- (d-2-formyloxy-2- phenylace tamido -3- 1-methyl-14-tetrazole-5-yl-thiomethyl)-3-cephem-40-carboxylique - Google Patents
Compositions pharmaceutiques antibiotiques contenant le sel de sodium de l'acide 7- (d-2-formyloxy-2- phenylace tamido -3- 1-methyl-14-tetrazole-5-yl-thiomethyl)-3-cephem-40-carboxyliqueInfo
- Publication number
- BE825653A BE825653A BE1006466A BE1006466A BE825653A BE 825653 A BE825653 A BE 825653A BE 1006466 A BE1006466 A BE 1006466A BE 1006466 A BE1006466 A BE 1006466A BE 825653 A BE825653 A BE 825653A
- Authority
- BE
- Belgium
- Prior art keywords
- phenylace
- tamido
- cephem
- formyloxy
- thiomethyl
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- NOJNFULGOQGBKB-UHFFFAOYSA-M sodium;3-[3-tert-butylsulfanyl-1-[[4-(6-ethoxypyridin-3-yl)phenyl]methyl]-5-[(5-methylpyridin-2-yl)methoxy]indol-2-yl]-2,2-dimethylpropanoate Chemical compound [Na+].C1=NC(OCC)=CC=C1C(C=C1)=CC=C1CN1C2=CC=C(OCC=3N=CC(C)=CC=3)C=C2C(SC(C)(C)C)=C1CC(C)(C)C([O-])=O NOJNFULGOQGBKB-UHFFFAOYSA-M 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US444622A US3928592A (en) | 1974-02-22 | 1974-02-22 | Antibiotic pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
BE825653A true BE825653A (fr) | 1975-08-18 |
Family
ID=23765656
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE1006466A BE825653A (fr) | 1974-02-22 | 1975-02-18 | Compositions pharmaceutiques antibiotiques contenant le sel de sodium de l'acide 7- (d-2-formyloxy-2- phenylace tamido -3- 1-methyl-14-tetrazole-5-yl-thiomethyl)-3-cephem-40-carboxylique |
Country Status (24)
Country | Link |
---|---|
US (1) | US3928592A (de) |
JP (1) | JPS6119605B2 (de) |
AR (1) | AR203895A1 (de) |
AT (1) | AT356264B (de) |
BE (1) | BE825653A (de) |
CA (1) | CA1043261A (de) |
CH (1) | CH620929A5 (de) |
CS (1) | CS189689B2 (de) |
DD (1) | DD117807A5 (de) |
DE (1) | DE2506622C2 (de) |
DK (1) | DK153919C (de) |
ES (1) | ES434976A1 (de) |
FR (1) | FR2261772B1 (de) |
GB (1) | GB1493676A (de) |
HU (1) | HU174129B (de) |
IE (1) | IE40671B1 (de) |
IL (1) | IL46650A (de) |
NL (1) | NL179976C (de) |
PH (1) | PH12058A (de) |
PL (1) | PL109311B1 (de) |
SE (1) | SE406153B (de) |
SU (1) | SU659094A3 (de) |
YU (1) | YU41875A (de) |
ZA (1) | ZA75975B (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5283956A (en) * | 1976-01-01 | 1977-07-13 | Lilly Co Eli | Antibiotic method and medical composition |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4054738A (en) * | 1975-12-22 | 1977-10-18 | Eli Lilly And Company | Sodium cefamandole crystalline forms |
JPS5329936A (en) * | 1976-08-31 | 1978-03-20 | Takeda Chem Ind Ltd | Antibiotic composition |
JPS5711909A (en) * | 1980-06-23 | 1982-01-21 | Shionogi & Co Ltd | Stable freeze-dried preparation of beta-lactam |
IL93618A0 (en) * | 1989-03-06 | 1990-12-23 | Lilly Co Eli | Improved diluent formulation for daptomycin |
JP4873207B2 (ja) * | 2001-02-26 | 2012-02-08 | 東レ・ファインケミカル株式会社 | 光学活性カルボン酸クロリドの精製方法 |
CN100554271C (zh) * | 2007-07-27 | 2009-10-28 | 苏州中联化学制药有限公司 | 抗菌素头孢孟多酯钠的合成方法 |
CN101880290B (zh) * | 2010-06-28 | 2012-03-07 | 海南新中正制药有限公司 | 头孢孟多酯钠的制备方法 |
WO2013057197A1 (en) * | 2011-10-20 | 2013-04-25 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Process for the formylation of cefamandole |
WO2013057196A1 (en) * | 2011-10-20 | 2013-04-25 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Process for the preparation of cefamandole nafate |
US9834567B1 (en) * | 2014-12-16 | 2017-12-05 | Tianjin University | Crystalline form of cefamandole nafate compound, preparation and preparing method thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1767891C3 (de) * | 1968-06-28 | 1980-10-30 | Pfizer | Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat |
US3641021A (en) * | 1969-04-18 | 1972-02-08 | Lilly Co Eli | 3 7-(ring-substituted) cephalosporin compounds |
-
1974
- 1974-02-22 US US444622A patent/US3928592A/en not_active Expired - Lifetime
-
1975
- 1975-02-05 JP JP50015230A patent/JPS6119605B2/ja not_active Expired
- 1975-02-17 ZA ZA00750975A patent/ZA75975B/xx unknown
- 1975-02-17 DE DE2506622A patent/DE2506622C2/de not_active Expired
- 1975-02-18 IL IL46650A patent/IL46650A/en unknown
- 1975-02-18 BE BE1006466A patent/BE825653A/xx not_active IP Right Cessation
- 1975-02-18 FR FR7505039A patent/FR2261772B1/fr not_active Expired
- 1975-02-19 AR AR257697A patent/AR203895A1/es active
- 1975-02-20 GB GB7111/75A patent/GB1493676A/en not_active Expired
- 1975-02-20 AT AT128475A patent/AT356264B/de not_active IP Right Cessation
- 1975-02-20 PL PL1975178215A patent/PL109311B1/pl unknown
- 1975-02-20 DD DD184320A patent/DD117807A5/xx unknown
- 1975-02-20 NL NLAANVRAGE7502045,A patent/NL179976C/xx not_active IP Right Cessation
- 1975-02-21 DK DK065575A patent/DK153919C/da not_active IP Right Cessation
- 1975-02-21 HU HU75EI599A patent/HU174129B/hu unknown
- 1975-02-21 ES ES434976A patent/ES434976A1/es not_active Expired
- 1975-02-21 CS CS751158A patent/CS189689B2/cs unknown
- 1975-02-21 CA CA220,537A patent/CA1043261A/en not_active Expired
- 1975-02-21 SU SU752109902A patent/SU659094A3/ru active
- 1975-02-21 SE SE7501985A patent/SE406153B/xx not_active IP Right Cessation
- 1975-02-21 PH PH16830A patent/PH12058A/en unknown
- 1975-02-21 YU YU00418/75A patent/YU41875A/xx unknown
- 1975-02-21 IE IE356/75A patent/IE40671B1/xx unknown
- 1975-02-21 CH CH216575A patent/CH620929A5/de not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5283956A (en) * | 1976-01-01 | 1977-07-13 | Lilly Co Eli | Antibiotic method and medical composition |
Also Published As
Publication number | Publication date |
---|---|
CA1043261A (en) | 1978-11-28 |
HU174129B (hu) | 1979-11-28 |
PH12058A (en) | 1978-10-18 |
DD117807A5 (de) | 1976-02-05 |
JPS6119605B2 (de) | 1986-05-17 |
DK153919C (da) | 1989-02-06 |
DK153919B (da) | 1988-09-26 |
SU659094A3 (ru) | 1979-04-25 |
ES434976A1 (es) | 1976-12-16 |
DE2506622C2 (de) | 1987-02-26 |
NL7502045A (nl) | 1975-08-26 |
AR203895A1 (es) | 1975-10-31 |
IE40671L (en) | 1975-08-22 |
NL179976B (nl) | 1986-07-16 |
FR2261772A1 (de) | 1975-09-19 |
AT356264B (de) | 1980-04-25 |
YU41875A (en) | 1982-05-31 |
SE7501985L (de) | 1975-08-25 |
SE406153B (sv) | 1979-01-29 |
PL109311B1 (en) | 1980-05-31 |
NL179976C (nl) | 1986-12-16 |
AU7833975A (en) | 1976-08-19 |
JPS50126817A (de) | 1975-10-06 |
IE40671B1 (en) | 1979-07-18 |
US3928592A (en) | 1975-12-23 |
CS189689B2 (en) | 1979-04-30 |
FR2261772B1 (de) | 1980-01-04 |
DE2506622A1 (de) | 1975-08-28 |
CH620929A5 (de) | 1980-12-31 |
DK65575A (de) | 1975-10-20 |
GB1493676A (en) | 1977-11-30 |
IL46650A0 (en) | 1975-05-22 |
ATA128475A (de) | 1979-09-15 |
IL46650A (en) | 1977-10-31 |
ZA75975B (en) | 1976-09-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE20 | Patent expired |
Owner name: ELI LILLY AND CY Effective date: 19950218 |