BE809234A - Nouveaux produits a activite anthelminthique - Google Patents

Nouveaux produits a activite anthelminthique

Info

Publication number
BE809234A
BE809234A BE139375A BE139375A BE809234A BE 809234 A BE809234 A BE 809234A BE 139375 A BE139375 A BE 139375A BE 139375 A BE139375 A BE 139375A BE 809234 A BE809234 A BE 809234A
Authority
BE
Belgium
Prior art keywords
emi
compound
mixture
methanol
chloroform
Prior art date
Application number
BE139375A
Other languages
English (en)
French (fr)
Inventor
C C Beard
J A Edwards
J H Fried
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of BE809234A publication Critical patent/BE809234A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/38—Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
BE139375A 1972-12-29 1973-12-28 Nouveaux produits a activite anthelminthique BE809234A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31929972A 1972-12-29 1972-12-29

Publications (1)

Publication Number Publication Date
BE809234A true BE809234A (fr) 1974-06-28

Family

ID=23241674

Family Applications (2)

Application Number Title Priority Date Filing Date
BE139376A BE809235A (fr) 1972-12-29 1973-12-28 Benzimidazole-2-carbamates a substitution en 5(6) sur le noyau benzenique
BE139375A BE809234A (fr) 1972-12-29 1973-12-28 Nouveaux produits a activite anthelminthique

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BE139376A BE809235A (fr) 1972-12-29 1973-12-28 Benzimidazole-2-carbamates a substitution en 5(6) sur le noyau benzenique

Country Status (5)

Country Link
JP (2) JPS5639016A (ru)
BE (2) BE809235A (ru)
DD (1) DD112450A5 (ru)
PL (1) PL99587B1 (ru)
ZA (2) ZA739220B (ru)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3978075A (en) * 1974-05-02 1976-08-31 Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt Substituted carbamoyl benzimidazole derivatives with antifungal properties
US3993769A (en) * 1972-12-29 1976-11-23 Syntex (U.S.A.) Inc. 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3996369A (en) * 1974-08-28 1976-12-07 Hoechst Aktiengesellschaft Anthelmintically active 2-carbalkoxyamino benzimidazolyl-5(6)-sulfonic acid phenyl esters
US3996368A (en) * 1974-08-24 1976-12-07 Hoechst Aktiengesellschaft Anthelmintically active 2-carbalkoxyamino-5(6)-phenyl sulfonyloxy benzimidazoles
US4002640A (en) * 1972-12-29 1977-01-11 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US4025638A (en) * 1975-03-10 1977-05-24 Smithkline Corporation Methods and compositions using 5-cycloalkylthio- and oxy-2-carbalkoxy-aminobenzimidazole
US4093732A (en) * 1977-02-17 1978-06-06 E. R. Squibb & Sons, Inc. Sulfoxide derivatives of benzimidazoles
US4258198A (en) * 1973-05-29 1981-03-24 Smithkline Corporation 5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63154063U (ru) * 1987-03-31 1988-10-11
EP2606726A1 (de) 2011-12-21 2013-06-26 Bayer CropScience AG N-Arylamidine-substituierte trifluoroethylsulfid-Derivate als Akarizide und Insektizide

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993769A (en) * 1972-12-29 1976-11-23 Syntex (U.S.A.) Inc. 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US4002640A (en) * 1972-12-29 1977-01-11 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US4258198A (en) * 1973-05-29 1981-03-24 Smithkline Corporation 5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles
US3978075A (en) * 1974-05-02 1976-08-31 Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt Substituted carbamoyl benzimidazole derivatives with antifungal properties
US3996368A (en) * 1974-08-24 1976-12-07 Hoechst Aktiengesellschaft Anthelmintically active 2-carbalkoxyamino-5(6)-phenyl sulfonyloxy benzimidazoles
US3996369A (en) * 1974-08-28 1976-12-07 Hoechst Aktiengesellschaft Anthelmintically active 2-carbalkoxyamino benzimidazolyl-5(6)-sulfonic acid phenyl esters
US4025638A (en) * 1975-03-10 1977-05-24 Smithkline Corporation Methods and compositions using 5-cycloalkylthio- and oxy-2-carbalkoxy-aminobenzimidazole
US4093732A (en) * 1977-02-17 1978-06-06 E. R. Squibb & Sons, Inc. Sulfoxide derivatives of benzimidazoles

Also Published As

Publication number Publication date
DD112450A5 (ru) 1975-04-12
JPS6023371A (ja) 1985-02-05
JPS6254786B2 (ru) 1987-11-17
ZA739219B (en) 1975-07-30
JPS624365B2 (ru) 1987-01-30
JPS5639016A (en) 1981-04-14
ZA739220B (en) 1975-07-30
BE809235A (fr) 1974-06-28
PL99587B1 (pl) 1978-07-31

Similar Documents

Publication Publication Date Title
EP0442820B1 (fr) Nouveaux dérivés de benzimidazole et d'azabenzimidazole, antagonistes des récepteurs au thromboxane; leurs procédés de préparation, intermédiaires de synthèse, compositions les contenant
JPS5939428B2 (ja) 駆虫効果を有する５（６）−ベンゼン環置換ベンズイミダゾ−ル−２−カルバメ−ト誘導体の製造方法
LU82272A1 (fr) Nouveau compose du benzodiazepine
FR2831883A1 (fr) Forme polymorphe du rimonabant, son procede de preparation et les compositions pharmaceutiques en contenant
CH643546A5 (fr) Procede pour la preparation de derives d'hydantoine.
EP0507696B1 (fr) Antihistaminiques non sédatifs, dérivés de benzimidazole, leur procédé de préparation et leur utilisation en tant que médicaments.
FR2599739A1 (fr) Acides biphenyl hydroxamiques a action therapeutique
EP0611766A1 (fr) Dérivés de 2-amido-thiazoles polysubstitués, procédé de préparation, composition pharmaceutique et utilisation de ces dérivés pour la préparation d'un médicament
BE809234A (fr) Nouveaux produits a activite anthelminthique
EP0109866A1 (fr) Nouveaux dérivés de la sulfonylurée, leurs procédés de préparation et les compositions pharmaceutiques les renfermant
CH640229A5 (fr) 1-(2-acylaminophenyl)imidazoles.
CH630382A5 (fr) Pyrroloquinoxalines et leurs sels.
EP0021924B1 (fr) Dérivés de l'indole, procédé pour leur préparation, leur application comme médicaments et compositions pharmaceutiques les contenant
CA2074365A1 (fr) Derives de l'uree, leur preparation et les medicaments les contenant
EP0201400B1 (fr) Dérivés du 4-phénylpropyl indole et leurs sels, leur procédé de préparation, leur application à titre de médicaments et les compositions pharmaceutiques les renfermant
EP0209435B1 (fr) Dérivés de l'hydroxy alkoxy 4-phénylpropyl indole, leurs sels, procédé et intermédiaires de préparation, application à titre de médicaments et compositions les renfermant
EP0176444B1 (fr) Nouveau procédé de préparation de dérivés du 4 H-1,2-4-triazole, nouveaux triazoles ainsi obtenus, leur applicication comme médicaments et les compositions pharmaceutiques les renfermant
CH639075A5 (fr) Ethers dibenzyliques substitues actifs sur le plan therapeutique.
EP0275762B1 (fr) Dérivés de l'indole carboxamide ainsi que leurs sels, procédé et intermédiaires de préparation, application à titre de médicaments de ces dérivés et compositions les renfermant
FR2500454A1 (fr) Nouveaux derives de l'ergoline, leur preparation et leur application comme medicaments
EP0076713B1 (fr) Nouveaux dérivés de l'aminométhyl 1H-indole 4-méthanol et leurs sels, leur procédé et les intermédiaires de préparation, leur application à titre de médicaments, les compositions les renfermant
EP0663903B1 (fr) Derives de dihydro-1,2 oxo-2 amino-3 quinoxalines, leur preparation et leur application en therapeutique
FR2560193A1 (fr) Derives d'aminodiaryl sulfoxyde, procede pour leur preparation et compositions pharmaceutiques et pesticides les contenant
LU84375A1 (fr) Nouveaux derives de n"-cyano n-oxydo-1 pyridinio-4 guanidine n'-substituee utiles comme medicaments antihypertenseurs et procede de leur preparation
US4080461A (en) 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity

Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: SYNTEX (U.S.A.) INC.

Effective date: 19931228