BE801108A - Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant - Google Patents

Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
BE801108A
BE801108A BE132425A BE132425A BE801108A BE 801108 A BE801108 A BE 801108A BE 132425 A BE132425 A BE 132425A BE 132425 A BE132425 A BE 132425A BE 801108 A BE801108 A BE 801108A
Authority
BE
Belgium
Prior art keywords
pyridopyrrolobenzheterocyclic
compounds
preparation
new
pharmaceutical compositions
Prior art date
Application number
BE132425A
Other languages
English (en)
French (fr)
Inventor
P Rajagopalan
Original Assignee
Endo Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endo Lab filed Critical Endo Lab
Publication of BE801108A publication Critical patent/BE801108A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/22—Eight-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/18—Eight-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE132425A 1972-06-19 1973-06-19 Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant BE801108A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26376672A 1972-06-19 1972-06-19
US357528A US3914421A (en) 1972-06-19 1973-05-07 Pyridopyrrolobenzheterocycles for combatting depression

Publications (1)

Publication Number Publication Date
BE801108A true BE801108A (fr) 1973-10-15

Family

ID=26950035

Family Applications (1)

Application Number Title Priority Date Filing Date
BE132425A BE801108A (fr) 1972-06-19 1973-06-19 Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant

Country Status (7)

Country Link
US (1) US3914421A (ja)
BE (1) BE801108A (ja)
DE (1) DE2330719A1 (ja)
FR (1) FR2189048B1 (ja)
IL (1) IL42430A0 (ja)
LU (1) LU67815A1 (ja)
NL (1) NL7308525A (ja)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4183936A (en) * 1972-06-19 1980-01-15 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
US4013652A (en) * 1972-06-19 1977-03-22 Endo Laboratories, Inc. Pyridopyrrolobenzoxazine
US4115577A (en) * 1972-06-19 1978-09-19 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
IT1119096B (it) * 1978-06-05 1986-03-03 Sankyo Co Derivati della benzotiazocina e della benzotiazonina particolarmente utili come medicamenti e procedimento per la loro preparazione
US4219550A (en) * 1978-11-09 1980-08-26 E. I. Du Pont De Nemours And Company Cis- and trans- octahydropyridopyrrolobenzheterocycles
EP0357417A1 (en) * 1988-09-01 1990-03-07 Glaxo Group Limited Lactam derivatives
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
EP0380155A1 (en) * 1989-01-19 1990-08-01 Duphar International Research B.V 8,9-Annelated-1,2,3,4-tetrahydro-beta-carboline derivatives
US6713471B1 (en) * 1999-06-15 2004-03-30 Bristol-Myers Squibb Pharma Company Substituted heterocycle fused gamma-carbolines
CN1371374A (zh) 1999-06-15 2002-09-25 杜邦药品公司 取代的杂环稠合γ－咔啉
US7071186B2 (en) 1999-06-15 2006-07-04 Bristol-Myers Squibb Pharma Co. Substituted heterocycle fused gamma-carbolines
EE200300301A (et) 2000-12-20 2003-10-15 Bristol-Myers Squibb Pharma Company Asendatud pürasinokinoksaliini derivaadid kui serotoniiniretseptorite agonistid ja antagonistid
JP4386639B2 (ja) 2000-12-20 2009-12-16 ブリストル−マイヤーズ スクイブ カンパニー セロトニンアゴニストおよびアンタゴニストとしての置換されたピロロキノリン化合物およびピリドキノリン化合物
US6849619B2 (en) * 2000-12-20 2005-02-01 Bristol-Myers Squibb Company Substituted pyridoindoles as serotonin agonists and antagonists
HUP0303432A3 (en) * 2000-12-20 2012-09-28 Bristol Myers Squibb Co Substituted pyridoindoles as serotonin agonists and antagonists and pharmaceutical compositions containing the compounds and their use
WO2003024976A2 (en) * 2001-09-21 2003-03-27 Pharmacia & Upjohn Company Tricyclic indole derivatives as 5-ht ligands
AU2003303210A1 (en) * 2002-12-19 2004-07-14 Bristol-Myers Squibb Company Substituted tricyclic gamma-carbolines as serotonin receptor agonists and antagonists
KR102107954B1 (ko) 2007-03-12 2020-05-07 인트라-셀룰라 써래피스, 인코퍼레이티드. 치환된 헤테로환 융합 감마-카르볼린 합성
US8575186B2 (en) 2009-10-05 2013-11-05 Albany Molecular Research, Inc. Epiminocycloalkyl[b] indole derivatives as serotonin sub-type 6 (5-HT6) modulators and uses thereof
WO2012099952A2 (en) 2011-01-19 2012-07-26 Albany Molecular Research, Inc. Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-ht6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia
WO2013155504A1 (en) 2012-04-14 2013-10-17 Intra-Cellular Therapies, Inc. Novel methods
PT2968320T (pt) 2013-03-15 2021-01-28 Intra Cellular Therapies Inc Compostos orgânicos
IL293523B2 (en) * 2013-12-03 2024-02-01 Intra Cellular Therapies Inc Lometaferon for use in the treatment of type I and/or type II bipolar disorders
RU2020123764A (ru) 2014-04-04 2020-08-05 Интра-Селлулар Терапиз, Инк. Органические соединения
AU2015240526A1 (en) 2014-04-04 2016-11-24 Intra-Cellular Therapies, Inc. Organic compounds
IL296884B2 (en) 2016-01-26 2024-05-01 Intra Cellular Therapies Inc Condensed heterocyclic converted gamma carbonyls for use in the treatment of central nervous system disorders
ES2879888T3 (es) 2016-03-25 2021-11-23 Intra Cellular Therapies Inc Compuestos orgánicos y su uso en el tratamiento o prevención de trastornos del sistema nervioso central
US11014925B2 (en) 2016-03-28 2021-05-25 Intra-Cellular Therapies, Inc. Co-crystals of 1-(4-fluoro-phenyl)-4-((6bR,1OaS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H,7H- pyrido[3′,4′:4,51_pyrrolo [1,2,3-delqcuinoxalin-8-yl)-butan-1-one with nicotinamide or isonicotinamide
WO2017172784A1 (en) 2016-03-28 2017-10-05 Intra-Cellular Therapies, Inc. Novel salts and crystals
EP3436083A4 (en) 2016-03-28 2019-11-27 Intra-Cellular Therapies, Inc. NEW COMPOSITIONS AND METHODS
EP3525763A4 (en) 2016-10-12 2020-06-17 Intra-Cellular Therapies, Inc. AMORPHE FIXED DISPERSIONS
WO2018126140A1 (en) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Organic compounds
WO2018126143A1 (en) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Organic compounds
KR20220066988A (ko) 2017-03-24 2022-05-24 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 조성물 및 방법
CA3071137A1 (en) 2017-07-26 2019-01-31 Intra-Cellular Therapies, Inc. Prodrugs of substituted heterocycle fused gamma-carbolines
IL272249B2 (en) 2017-07-26 2023-11-01 Intra Cellular Therapies Inc organic compounds
EP3801527A4 (en) 2018-06-08 2022-03-30 Intra-Cellular Therapies, Inc. NEW METHODS
CA3240552A1 (en) 2018-06-11 2019-12-19 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines synthesis
AU2019331490A1 (en) 2018-08-31 2021-03-18 Intra-Cellular Therapies, Inc. Novel methods
EP3843738A4 (en) 2018-08-31 2022-06-01 Intra-Cellular Therapies, Inc. NEW METHODS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH307223A (de) * 1952-04-28 1955-05-15 Bayer Ag Verfahren zur Herstellung eines Derivates des Tetrahydro-y-carbolins.

Also Published As

Publication number Publication date
IL42430A0 (en) 1973-08-29
FR2189048A1 (ja) 1974-01-25
FR2189048B1 (ja) 1976-10-22
LU67815A1 (ja) 1973-09-26
NL7308525A (ja) 1973-12-21
DE2330719A1 (de) 1974-01-10
US3914421A (en) 1975-10-21

Similar Documents

Publication Publication Date Title
BE801108A (fr) Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant
BE771493A (fr) Nouveaux derives de l'isoindoline, leur preparation et les compositionsqui les contiennent
BE826709A (fr) Nouveaux composes heterocycliques, leur preparation et medicament les contenant
FR2347365A1 (fr) Trans-hexahydro-pyrido-indoles, leur preparation et compositions pharmaceutiques les contenant
BE764660A (fr) Nouveaux derives de l'indole, leur preparation et medicaments contenantces derives
BE764659A (fr) Nouveaux derives de l'indole, leur preparation et medicaments contenantces derives
FR2283686A1 (fr) Nouveaux composes heterocycliques et compositions pharmaceutiques les contenant
BE776682A (fr) Nouveaux derives de l'isoindoline, leur preparation et les compositionsmedicinales qui les contiennent
BE746301A (fr) Nouveaux benzylimidazoles alpha, alpha-disubstitues, leur procede de preparation et compositions pharmaceutiques les contenant
BE796828A (fr) Nouveaux derives de l'isoindoline leur preparation et les compositions medicinales qui les contiennent
BE800311A (fr) Aminohalopyridines substituees, leur preparation et compositions en contenant
BE777911A (fr) Nouveaux composes heterocycliques, leur preparation et compositions pharmaceutiques les contenant
BE848227A (fr) Nouveaux composes heterocycliques et compositions pharmaceutiques les contenant,
BE806854A (fr) Nouvelles urees tricycliques, leur preparation et les compositions pharmaceutiques en contenant
FR2290193A1 (fr) Derives de n2-naphtalenesulfonyl-l-arginine, leur preparation et compositions pharmaceutiques les contenant
BE803474A (fr) Nouvelles 2-alkylamino-dihydropyridines, leur procede de preparation et compositions pharmaceutiques les contenant
BE786031A (fr) Nouveaux derives de la phenanthridine, leur preparation et les compositions medicinales qui les contiennent
FR2340310A1 (fr) Hydrazinophtalazines substituees, leur preparation et compositions pharmaceutiques les contenant
BE775294A (fr) Nouveaux derives de la pyridazine, leur preparation et medicaments les contenant
FR2310132A1 (fr) 14b-hydroxy-3-desoxycardenolides et analogues de ceux-ci, leur preparation et compositions pharmaceutiques les contenant
BE793851A (fr) Nouveaux derives de l'isoindoline, leur preparation et les compositions medicinales qui les contiennent
BE832121A (fr) Nouveaux composes anti-arythmiques et compositions pharmaceutiques les contenant
BE808094A (fr) Nouveaux derives de propanolamine et composition pharmaceutique les contenant
BE761713A (fr) Nouvelles pyrrolidines substituees, leur preparation et compositions pharmaceutiques les contenant
BE778564A (fr) Nouveaux esters d'ara-cytidine, leur preparation et compositions pharmaceutiques les contenant