BE766390A - Derives aminocetoniques du phloroglucinol - Google Patents
Derives aminocetoniques du phloroglucinolInfo
- Publication number
- BE766390A BE766390A BE766390A BE766390A BE766390A BE 766390 A BE766390 A BE 766390A BE 766390 A BE766390 A BE 766390A BE 766390 A BE766390 A BE 766390A BE 766390 A BE766390 A BE 766390A
- Authority
- BE
- Belgium
- Prior art keywords
- aminocetonic
- phloroglucinol
- derivatives
- aminocetonic derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
- C07C43/2055—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2186570 | 1970-05-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
BE766390A true BE766390A (fr) | 1971-09-16 |
Family
ID=10170122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE766390A BE766390A (fr) | 1970-05-06 | 1971-04-28 | Derives aminocetoniques du phloroglucinol |
Country Status (12)
Country | Link |
---|---|
US (1) | US3895030A (ko) |
JP (1) | JPS5123492B1 (ko) |
AU (1) | AU2849871A (ko) |
BE (1) | BE766390A (ko) |
CA (1) | CA935431A (ko) |
CH (1) | CH530369A (ko) |
DE (1) | DE2122144A1 (ko) |
ES (1) | ES390905A1 (ko) |
FR (1) | FR2092133B1 (ko) |
GB (1) | GB1325192A (ko) |
LU (1) | LU63096A1 (ko) |
NL (1) | NL174143C (ko) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2404003A1 (fr) * | 1977-09-26 | 1979-04-20 | Lafon Labor | Nouveaux derives de phloroglucinol, leur procede de preparation et leur application en therapeutique |
DE2841702C2 (de) * | 1977-09-26 | 1994-08-04 | Lafon Labor | Verwendung von (2,4,6-Trihydroxyphenyl)-(3-pyrrolidinopropyl)keton zur Hemmung der Blutplättchenaggregation und zur Behandlung des Wundliegens |
JPS56104835A (en) * | 1980-01-23 | 1981-08-20 | Shionogi & Co Ltd | Novel synthesis of 2-haloacetylphenols |
FR2503143A1 (fr) * | 1981-03-31 | 1982-10-08 | Lafon Labor | Nouveaux derives de phenacylamine, leur utilisation en therapeutique et leur procede de preparation |
FR2504136A1 (fr) * | 1981-04-15 | 1982-10-22 | Lafon Labor | (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-cetone et ses sels d'addition, utilisation en therapeutique et procede de preparation |
FR2534916B1 (fr) * | 1982-10-26 | 1985-11-22 | Lafon Labor | Nouveaux derives de phenyl-(3-aminopropyl)-cetone, utilisation en therapeutique et procede de preparation |
FR2534912B1 (fr) * | 1982-10-26 | 1985-06-28 | Lafon Labor | Nouveaux derives de (2,4,6-trimethoxyphenyl) - (3-piperidinopropyl) -cetone, utilisation en therapeutique et procede de preparation |
FR2555576B1 (fr) * | 1983-11-25 | 1986-06-13 | Lafon Labor | Derives de n-(methoxyphenacyl)-amine, utilisation notamment en therapeutique et procede de preparation |
DE3520910C2 (de) * | 1985-06-11 | 1987-04-02 | Avesta Nyby Powder AB, Torshälla | Verfahren zur Herstellung von Strangpreßbolzen, zur pulvermetallurgischen Erzeugung von Rohren |
FR2584715B1 (fr) * | 1985-07-10 | 1987-10-09 | Lafon Labor | Phenyl-(3-hexamethyleneiminopropyl)-cetone, procede de preparation et utilisation en therapeutique |
FR2597864B1 (fr) * | 1986-04-28 | 1990-11-16 | Lafon Labor | Nouveaux derives de la n-((trimethoxy-2,4,6-benzoyl)-3 propyl) piperidine, leurs procedes de preparation et leur application en therapeutique |
US4870083A (en) * | 1987-11-24 | 1989-09-26 | Merrell Dow Pharmaceuticals Inc. | 1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants |
IT1231260B (it) * | 1988-11-16 | 1991-11-28 | Sergio Bertini Curri | Farmaco e metodo per aumentare volume e velocita' del flusso microcircolatorio capillare a livello cutaneo |
OA12905A (en) | 2002-08-19 | 2006-10-13 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases. |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
GB0410215D0 (en) * | 2004-05-07 | 2004-06-09 | Lescroart Pol | Nerve damage |
GB2414665A (en) * | 2004-06-01 | 2005-12-07 | Pol Lescroart | Aminoketone derivatives of phloroglucinol for the treatment of motor neuron disease |
US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
US8383660B2 (en) | 2006-03-10 | 2013-02-26 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
WO2007136790A2 (en) | 2006-05-18 | 2007-11-29 | Mannkind Corporation | Intracellular kinase inhibitors |
US8404896B2 (en) | 2006-12-01 | 2013-03-26 | Bristol-Myers Squibb Company | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
JP4827986B2 (ja) | 2007-06-08 | 2011-11-30 | マンカインド コーポレ−ション | IRE−1αインヒビター |
CN101220006B (zh) * | 2007-12-19 | 2010-09-01 | 齐鲁天和惠世制药有限公司 | 丁咯地尔的制备方法 |
CN102898404A (zh) * | 2012-10-11 | 2013-01-30 | 南通康鑫药业有限公司 | 一种盐酸丁咯地尔的制备方法 |
JP2016516804A (ja) | 2013-04-17 | 2016-06-09 | ファイザー・インク | 心血管疾患を治療するためのn−ピペリジン−3−イルベンズアミド誘導体 |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CN105924411B (zh) * | 2016-05-10 | 2018-12-11 | 王珍 | 一种盐酸丁咯地尔化合物及其药物组合物 |
JOP20210193A1 (ar) | 2019-01-18 | 2023-01-30 | Astrazeneca Ab | مثبطات pcsk9 وطرق استخدامها |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1115992A (en) * | 1965-03-26 | 1968-06-06 | Lafon Labor | Improvements in or relating to n-piperidino-alkoxyacetophenones |
-
1971
- 1971-04-20 FR FR7114011A patent/FR2092133B1/fr not_active Expired
- 1971-04-27 CH CH619171A patent/CH530369A/fr not_active IP Right Cessation
- 1971-04-28 BE BE766390A patent/BE766390A/xx not_active IP Right Cessation
- 1971-05-03 US US139894A patent/US3895030A/en not_active Expired - Lifetime
- 1971-05-04 AU AU28498/71A patent/AU2849871A/en not_active Expired
- 1971-05-04 LU LU63096D patent/LU63096A1/xx unknown
- 1971-05-05 NL NLAANVRAGE7106122,A patent/NL174143C/xx not_active IP Right Cessation
- 1971-05-05 ES ES390905A patent/ES390905A1/es not_active Expired
- 1971-05-05 DE DE19712122144 patent/DE2122144A1/de active Pending
- 1971-05-05 CA CA112197A patent/CA935431A/en not_active Expired
- 1971-05-06 GB GB2186570A patent/GB1325192A/en not_active Expired
- 1971-05-06 JP JP46029486A patent/JPS5123492B1/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
FR2092133B1 (ko) | 1974-03-22 |
NL174143B (nl) | 1983-12-01 |
GB1325192A (en) | 1973-08-01 |
ES390905A1 (es) | 1973-06-01 |
NL7106122A (ko) | 1971-11-09 |
CA935431A (en) | 1973-10-16 |
LU63096A1 (ko) | 1971-08-31 |
AU2849871A (en) | 1972-11-09 |
US3895030A (en) | 1975-07-15 |
NL174143C (nl) | 1984-05-01 |
FR2092133A1 (ko) | 1972-01-21 |
DE2122144A1 (de) | 1971-11-25 |
CH530369A (fr) | 1972-11-15 |
JPS5123492B1 (ko) | 1976-07-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE20 | Patent expired |
Owner name: S.A. ORSYMONDE Effective date: 19910428 |