BE751299A - Dna polyamine compositions for treating - lesions caused by radiation - Google Patents
Dna polyamine compositions for treating - lesions caused by radiationInfo
- Publication number
- BE751299A BE751299A BE751299DA BE751299A BE 751299 A BE751299 A BE 751299A BE 751299D A BE751299D A BE 751299DA BE 751299 A BE751299 A BE 751299A
- Authority
- BE
- Belgium
- Prior art keywords
- dna
- radiation
- lesions caused
- treating
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
DNA-polyamine composition for treating lesions caused by radiation. Compns. are prepared by dissolving dioxyri bonucleic acid (DNA) and a basic amine or amino-acid separately in dilute sodium chloride solution opt. containing sodium citrate, mixing the two solutions at 37 degrees C for 6-36 hrs. and at pH 7, adding ethanol and recovering the precipitate formed by centrifuging. Suitable amines and amino-acids are spermine, spermidine, cadaverine, polylysine and polyarginine. The compositions may be used to cure lesions caused by radiation e.g. white corpuscle destruction and can be used to treat secondary effects in the X-ray and gamma-ray treatments for cancer.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE751299 | 1970-06-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
BE751299A true BE751299A (en) | 1970-11-16 |
Family
ID=3856574
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE751299D BE751299A (en) | 1970-06-01 | 1970-06-02 | Dna polyamine compositions for treating - lesions caused by radiation |
Country Status (1)
Country | Link |
---|---|
BE (1) | BE751299A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996022792A1 (en) * | 1995-01-25 | 1996-08-01 | Amgen Inc. | Cationic copolymers of vinylamine and vinyl alcohol for the delivery of oligonucleotides |
-
1970
- 1970-06-02 BE BE751299D patent/BE751299A/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996022792A1 (en) * | 1995-01-25 | 1996-08-01 | Amgen Inc. | Cationic copolymers of vinylamine and vinyl alcohol for the delivery of oligonucleotides |
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