GB1003802A
(en)
*
|
1963-06-04 |
1965-09-08 |
Searle & Co |
Pyrimidinone derivatives
|
GB1062357A
(en)
*
|
1965-03-23 |
1967-03-22 |
Pfizer & Co C |
Quinazolone derivatives
|
DE2027645A1
(de)
*
|
1970-06-05 |
1971-12-09 |
Byk Gulden Lomberg Chemische Fa bnk GmbH, 7750 Konstanz |
Piperazinylalkyl chinazolon (4) den vate, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel
|
US3900476A
(en)
*
|
1973-05-17 |
1975-08-19 |
Upjohn Co |
2(2'-pyrimidylamino)quinazolines and their preparation
|
US3959279A
(en)
*
|
1974-01-28 |
1976-05-25 |
Sandoz, Inc. |
1-Substituted-2-imino-quinazolin-4(1H)ones
|
US3936453A
(en)
*
|
1974-01-28 |
1976-02-03 |
Sandoz, Inc. |
1-Substituted-2-disubstituted aminoquin azolin-4(1h)-ones
|
US4113637A
(en)
*
|
1974-09-10 |
1978-09-12 |
Institut Francais Du Petrole |
Alkyl-guanidino-heterocyclic compounds, their manufacture and use as additives for fuels and lubricants
|
GB8429739D0
(en)
*
|
1984-11-24 |
1985-01-03 |
Fbc Ltd |
Fungicides
|
US5756502A
(en)
*
|
1994-08-08 |
1998-05-26 |
Warner-Lambert Company |
Quinazolinone derivatives as cholyecystokinin (CCK) ligands
|
WO1997010221A1
(en)
*
|
1995-09-15 |
1997-03-20 |
Torrey Pines Institute For Molecular Studies |
Synthesis of quinazolinone libraries
|
US6258819B1
(en)
*
|
1999-08-05 |
2001-07-10 |
Syntex (U.S.A.) Llc |
Substituted 2(4-piperidyl)-4(3H)-quinazolinones and 2-(4-piperidyl)-4(3H)-azaquinazolinones
|
US6545004B1
(en)
|
1999-10-27 |
2003-04-08 |
Cytokinetics, Inc. |
Methods and compositions utilizing quinazolinones
|
US7671200B2
(en)
*
|
1999-10-27 |
2010-03-02 |
Cytokinetics, Inc. |
Quinazolinone KSP inhibitors
|
US7230000B1
(en)
*
|
1999-10-27 |
2007-06-12 |
Cytokinetics, Incorporated |
Methods and compositions utilizing quinazolinones
|
US6667300B2
(en)
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
US6518277B1
(en)
*
|
2000-04-25 |
2003-02-11 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
JPWO2002094790A1
(ja)
*
|
2001-05-23 |
2004-09-09 |
三菱ウェルファーマ株式会社 |
縮合ヘテロ環化合物およびその医薬用途
|
AU2002363429B2
(en)
|
2001-11-07 |
2008-05-08 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
US6753428B2
(en)
*
|
2001-11-20 |
2004-06-22 |
Cytokinetics, Inc. |
Process for the racemization of chiral quinazolinones
|
JP2005529076A
(ja)
*
|
2002-02-15 |
2005-09-29 |
サイトキネティクス・インコーポレーテッド |
キナゾリノンの合成
|
CN100491358C
(zh)
*
|
2002-05-09 |
2009-05-27 |
赛特凯恩蒂克公司 |
嘧啶酮类化合物、组合物及方法
|
WO2003097053A1
(en)
|
2002-05-09 |
2003-11-27 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
EP1513820A4
(en)
*
|
2002-05-23 |
2006-09-13 |
Cytokinetics Inc |
COMPOUNDS, COMPOSITIONS AND METHODS
|
AU2003236527A1
(en)
*
|
2002-06-14 |
2003-12-31 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
AU2003256805A1
(en)
*
|
2002-07-23 |
2004-02-09 |
Cytokinetics, Inc. |
Compounds compositions and methods
|
WO2004018058A2
(en)
*
|
2002-08-21 |
2004-03-04 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
EP1558083A4
(en)
*
|
2002-09-30 |
2008-04-16 |
Cytokinetics Inc |
COMPOUNDS, COMPOSITIONS AND METHODS
|
US7687625B2
(en)
*
|
2003-03-25 |
2010-03-30 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
EP1506967B1
(en)
|
2003-08-13 |
2007-11-21 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
US20050054614A1
(en)
*
|
2003-08-14 |
2005-03-10 |
Diacovo Thomas G. |
Methods of inhibiting leukocyte accumulation
|
WO2005016348A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Method of inhibiting immune responses stimulated by an endogenous factor
|
JP2007505121A
(ja)
*
|
2003-09-08 |
2007-03-08 |
武田薬品工業株式会社 |
ジペプチジルぺプチダーゼ阻害剤
|
EP1697342A2
(en)
*
|
2003-09-08 |
2006-09-06 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
JP2007510652A
(ja)
*
|
2003-11-03 |
2007-04-26 |
サイトキネティクス・インコーポレーテッド |
ピリミジン−4−オン化合物、組成物、および方法
|
EP1680420A4
(en)
*
|
2003-11-07 |
2008-09-24 |
Cytokinetics Inc |
COMPOUNDS, COMPOSITIONS AND METHODS
|
US7439254B2
(en)
*
|
2003-12-08 |
2008-10-21 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
CN102127057A
(zh)
*
|
2004-03-15 |
2011-07-20 |
武田药品工业株式会社 |
二肽基肽酶抑制剂
|
PT1761540T
(pt)
|
2004-05-13 |
2016-12-07 |
Icos Corp |
Quinazolinonas como inibidores de fosfatidilinositol-3-cinase delta humana
|
CA2567883A1
(en)
*
|
2004-05-25 |
2005-12-15 |
Icos Corporation |
Methods for treating and/or preventing aberrant proliferation of hematopoietic cells
|
WO2006068978A2
(en)
|
2004-12-21 |
2006-06-29 |
Takeda Pharmaceutial Company Limited |
Dipeptidyl peptidase inhibitors
|
US20080287469A1
(en)
*
|
2005-02-17 |
2008-11-20 |
Diacovo Thomas G |
Phosphoinositide 3-Kinase Inhibitors for Inhibiting Leukocyte Accumulation
|
DE102005024017A1
(de)
*
|
2005-05-25 |
2006-11-30 |
Merck Patent Gmbh |
Chinazolinone
|
PE20070622A1
(es)
*
|
2005-09-14 |
2007-08-22 |
Takeda Pharmaceutical |
Administracion de inhibidores de dipeptidil peptidasa
|
EP1942898B2
(en)
|
2005-09-14 |
2014-05-14 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors for treating diabetes
|
KR101368988B1
(ko)
*
|
2005-09-16 |
2014-02-28 |
다케다 야쿠힌 고교 가부시키가이샤 |
디펩티딜 펩티다제 억제제
|
US8349850B2
(en)
*
|
2006-03-28 |
2013-01-08 |
Atir Holding S.A. |
Heterocyclic compounds and uses thereof in the treatment of sexual disorders
|
EP1999108A1
(en)
*
|
2006-03-28 |
2008-12-10 |
Takeda Pharmaceutical Company Limited |
Preparation of (r)-3-aminopiperidine dihydrochloride
|
PE20081150A1
(es)
*
|
2006-09-13 |
2008-10-03 |
Takeda Pharmaceutical |
Inhibidores de dipetidilpeptidasa
|
US8324383B2
(en)
|
2006-09-13 |
2012-12-04 |
Takeda Pharmaceutical Company Limited |
Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
|
TW200838536A
(en)
*
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
US8093236B2
(en)
|
2007-03-13 |
2012-01-10 |
Takeda Pharmaceuticals Company Limited |
Weekly administration of dipeptidyl peptidase inhibitors
|
CN102271683B
(zh)
|
2008-11-13 |
2014-07-09 |
吉里德卡利斯托加公司 |
恶性血液病的治疗
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
WO2010111432A1
(en)
|
2009-03-24 |
2010-09-30 |
Calistoga Pharmaceuticals Inc. |
Atropisomers of2-purinyl-3-tolyl-quinazolinone derivatives and methods of use
|
AU2010239312A1
(en)
*
|
2009-04-20 |
2011-11-10 |
Gilead Calistoga Llc |
Methods of treatment for solid tumors
|
KR20120049281A
(ko)
|
2009-07-21 |
2012-05-16 |
길리아드 칼리스토가 엘엘씨 |
Pi3k 억제제를 이용한 간 장애의 치료
|
EP3581567A1
(en)
|
2011-04-10 |
2019-12-18 |
Atir Holding S.A. |
Heterocyclic compounds and uses thereof in the treatment of sexual disorders
|
CA2864305C
(en)
|
2012-03-05 |
2021-02-16 |
Gilead Calistoga Llc |
Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one
|
EP3083630B1
(en)
|
2013-12-20 |
2019-08-21 |
Gilead Calistoga LLC |
Process methods for phosphatidylinositol 3-kinase inhibitors
|
EP3083623A1
(en)
|
2013-12-20 |
2016-10-26 |
Gilead Calistoga LLC |
Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
|
SG11201609877XA
(en)
|
2014-06-13 |
2016-12-29 |
Gilead Sciences Inc |
Phosphatidylinositol 3-kinase inhibitors
|