BE638369A - - Google Patents

Info

Publication number
BE638369A
BE638369A BE638369DA BE638369A BE 638369 A BE638369 A BE 638369A BE 638369D A BE638369D A BE 638369DA BE 638369 A BE638369 A BE 638369A
Authority
BE
Belgium
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of BE638369A publication Critical patent/BE638369A/xx
Priority claimed from GB3844462A external-priority patent/GB1049789A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE638369D 1962-10-10 BE638369A (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3844462A GB1049789A (en) 1963-04-17 1962-10-10 New thebaine derivatives and methods of preparing the same

Publications (1)

Publication Number Publication Date
BE638369A true BE638369A (enExample)

Family

ID=10403484

Family Applications (1)

Application Number Title Priority Date Filing Date
BE638369D BE638369A (enExample) 1962-10-10

Country Status (2)

Country Link
US (1) US3299072A (enExample)
BE (1) BE638369A (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342824A (en) * 1964-12-07 1967-09-19 Lilly Co Eli Normorphines
GB1123768A (en) * 1966-07-29 1968-08-14 Smith Kline French Lab New thebaine and oripavine derivatives and processes for preparing the same
US3466277A (en) * 1966-12-13 1969-09-09 Boehringer Sohn Ingelheim N-allylic cyclohexyl lower alkyl normorphines
US3905981A (en) * 1973-10-12 1975-09-16 Research Corp N-dealkylation of tertiary amines
NO802139L (no) * 1979-08-09 1981-02-10 Mallinckrodt Inc Utgangsforbindelser for fremstilling av morfinderivater, samt fremgangsmaate til fremstilling av utgangsforbindelsene
US4613668A (en) * 1983-12-22 1986-09-23 The United States Of America As Represented By The Department Of Health And Human Services Short total synthesis or morphinan compounds which uses cyclization of a cycloalkylcarbonyl compound selected from cyclopropylcarbonyl and cyclobutylcarbonyl
US4722928A (en) * 1985-12-02 1988-02-02 E. I. Du Pont De Nemours And Company N-oxide prodrug derivatives of 3-hydroxy morphinans and partial morphinans having improved oral bioavailability, pharmaceutical compositions, and processes
US4990617A (en) * 1985-12-02 1991-02-05 E. I. Du Pont De Nemours And Company N-oxide prodrug derivatives of 3-hydroxy morphinans and partial morphinans and derivatives
US5668285A (en) * 1986-10-31 1997-09-16 The United States Of America As Represented By The Department Of Health And Human Services Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
CA2067200C (en) * 1989-10-16 1998-06-30 Kenner C. Rice Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates
US5028612A (en) * 1990-03-22 1991-07-02 Hillel Glover Method for treating emotional numbness
EP1782834A3 (en) * 2003-03-13 2007-08-01 Controlled Chemicals, Inc. Oxycodone conjugates with lower abuse potential and extended duration of action
WO2004082620A2 (en) * 2003-03-13 2004-09-30 Controlled Chemicals, Inc. Oxycodone conjugates with lower the abuse potential and extended duration of action
ES2357216T3 (es) * 2005-06-16 2011-04-20 Mallinckrodt, Inc. Una ruta de síntesis de 14-hidroxil-opiáceos a través de 1-halo-tebaína o análogos.
US20090047279A1 (en) * 2006-11-22 2009-02-19 Progenics Pharmaceuticals, Inc. (R)-N-Stereoisomers of 7,8-Saturated-4,5-Epoxy-Morphinanium Analogs
CA2681740A1 (en) * 2007-03-23 2008-10-02 Mallinckrodt Inc. Improved preparation of oxymorphone from oripavine
DK2146961T3 (da) 2007-04-12 2014-04-28 Ivax Int Gmbh N-oxid- og/eller di-N-oxidderivater af dopaminreceptorstabilisatorer/modulatorer udvisende forbedrede cardiovaskulære bivirkningsprofiler
ES2423180T3 (es) * 2007-04-16 2013-09-18 Mallinckrodt Llc Nueva reducción de opiáceos mediante reacción de transferencia de hidrógeno catalítica
CA2709882A1 (en) 2007-12-17 2009-06-25 Peter X. Wang N-demethylation of n-methyl morphinans
PL2222642T3 (pl) * 2007-12-17 2014-07-31 SpecGx LLC Sposób i związki do wytwarzania (+) opiatów
WO2010039209A2 (en) * 2008-09-30 2010-04-08 Mallinckrodt Inc. Processes for the synthesis of tertiary amines
WO2011008636A1 (en) * 2009-07-15 2011-01-20 Mallinckrodt Inc. 3-oxy-hydromorphone derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3153042A (en) * 1964-10-13 Morphinone and codeinone derivatives
US2890221A (en) * 1957-07-24 1959-06-09 Rapoport Henry Method for preparing normorphine
US3101339A (en) * 1958-10-30 1963-08-20 Boehringer Sohn Ingelheim Quaternary salts of normorphine and its acylated derivatives

Also Published As

Publication number Publication date
US3299072A (en) 1967-01-17

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