BE628544A - - Google Patents
Info
- Publication number
- BE628544A BE628544A BE628544DA BE628544A BE 628544 A BE628544 A BE 628544A BE 628544D A BE628544D A BE 628544DA BE 628544 A BE628544 A BE 628544A
- Authority
- BE
- Belgium
- Prior art keywords
- water
- complex
- antibiotic
- dry
- polypeptide
- Prior art date
Links
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 34
- 238000000034 method Methods 0.000 claims description 23
- 230000003115 biocidal effect Effects 0.000 claims description 20
- 239000000463 material Substances 0.000 claims description 17
- 239000003910 polypeptide antibiotic agent Substances 0.000 claims description 11
- 239000003125 aqueous solvent Substances 0.000 claims description 9
- 229920002554 vinyl polymer Polymers 0.000 claims description 9
- -1 polyoxyethylene Polymers 0.000 claims description 8
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 8
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 8
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 8
- 239000002904 solvent Substances 0.000 claims description 8
- GSXRBRIWJGAPDU-BBVRJQLQSA-N tyrocidine A Chemical compound C([C@H]1C(=O)N[C@H](C(=O)N[C@@H](CCCN)C(=O)N[C@H](C(N[C@H](CC=2C=CC=CC=2)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N1)=O)CC(C)C)C(C)C)C1=CC=C(O)C=C1 GSXRBRIWJGAPDU-BBVRJQLQSA-N 0.000 claims description 7
- 108010021006 Tyrothricin Proteins 0.000 claims description 6
- 229960003281 tyrothricin Drugs 0.000 claims description 6
- 239000003242 anti bacterial agent Substances 0.000 claims description 5
- 229920001184 polypeptide Polymers 0.000 claims description 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 5
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 claims description 4
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims description 4
- 229920001400 block copolymer Polymers 0.000 claims description 4
- 229920001577 copolymer Polymers 0.000 claims description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 2
- 238000001704 evaporation Methods 0.000 claims description 2
- 230000008020 evaporation Effects 0.000 claims description 2
- 239000004743 Polypropylene Substances 0.000 claims 2
- 229920001155 polypropylene Polymers 0.000 claims 2
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 claims 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 18
- 239000000243 solution Substances 0.000 description 14
- 229920000642 polymer Polymers 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
- 229920006316 polyvinylpyrrolidine Polymers 0.000 description 7
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 6
- 239000007864 aqueous solution Substances 0.000 description 5
- 229940088710 antibiotic agent Drugs 0.000 description 4
- 230000005764 inhibitory process Effects 0.000 description 4
- 230000001476 alcoholic effect Effects 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 108010026389 Gramicidin Proteins 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229960004905 gramicidin Drugs 0.000 description 2
- ZWCXYZRRTRDGQE-SORVKSEFSA-N gramicidina Chemical compound C1=CC=C2C(C[C@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC=3C4=CC=CC=C4NC=3)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC=3C4=CC=CC=C4NC=3)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC=3C4=CC=CC=C4NC=3)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC=O)C(C)C)CC(C)C)C(=O)NCCO)=CNC2=C1 ZWCXYZRRTRDGQE-SORVKSEFSA-N 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229920001983 poloxamer Polymers 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- VUEZBQJWLDBIDE-UHFFFAOYSA-N 3-ethenyl-1,3-oxazolidin-2-one Chemical compound C=CN1CCOC1=O VUEZBQJWLDBIDE-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000251730 Chondrichthyes Species 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 108010076164 Tyrocidine Proteins 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 125000005233 alkylalcohol group Chemical group 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000002036 drum drying Methods 0.000 description 1
- 229920006158 high molecular weight polymer Polymers 0.000 description 1
- 238000002789 length control Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000009149 molecular binding Effects 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE628544A true BE628544A (index.php) |
Family
ID=198376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE628544D BE628544A (index.php) |
Country Status (1)
| Country | Link |
|---|---|
| BE (1) | BE628544A (index.php) |
-
0
- BE BE628544D patent/BE628544A/fr unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3089818A (en) | Water dispersible antibiotics | |
| CN100352426C (zh) | 含有注射用药物的聚合物微囊制剂制造方法 | |
| EP1830898B1 (fr) | Composition polymere pour lentille intraoculaire | |
| FR2471213A1 (fr) | Composition absorbant l'eau, catheter, suture ou plaque de verre enduits de cette composition | |
| FR2488901A1 (fr) | Composition de matiere absorbante, procede de preparation d'une telle composition et articles confectionnes avec celle-ci | |
| EP3648809B1 (fr) | Materiau solide organique antibacterien | |
| JP2001517731A (ja) | ヒドロゲルの表面処理方法および同方法にて形成される物品 | |
| EP1328249B1 (fr) | Copolymeres amphiphiles utilisables notamment comme agent emulsionnant | |
| EP0687283B1 (fr) | Film d'elastomere comprenant des gouttelettes, son procede de preparation et ses applications | |
| Real et al. | Design, characterization, and in vitro evaluation of antifungal polymeric films | |
| EP0141768A1 (fr) | Procédé perfectionné d'obtention de liposomes unilamellaires de diamètres élevés, leur application pharmacologique pour l'encapsulage d'un principe actif en vue de son administration extemporanée et dispositif correspondant | |
| Ravindra et al. | Tensile and thermal properties of poly (vinyl pyrrolidone)/vanillin incorporated poly (vinyl alcohol) films | |
| FR2470638A1 (fr) | Composition absorbant l'eau, catheter, suture ou plaque de verre enduits de cette composition | |
| FR2944957A1 (fr) | Support cellulosique contenant des derives de mannose aptes a fixer les bacteries dotees de pilis de type 1, application aux lingettes desinfectantes notamment | |
| BE628544A (index.php) | ||
| CH660371A5 (fr) | Poly beta-alanine reticulee et ses differentes applications. | |
| BE1009403A3 (fr) | Composition souple a base de polymere de chlorure de vinyle, utilisation de cette composition pour la fabrication d'un article et article comprenant cette composition. | |
| Şanlı et al. | Release of salicylic acid through poly (vinyl alcohol)/poly (vinyl pyrrolidone) and poly (vinyl alcohol‐g‐N‐vinyl‐2‐pyrrolidone) membranes | |
| CA2394241C (fr) | Procede d'additivation minimisant la segregation des additifs et leur migration | |
| JPH05168909A (ja) | 高含水ヒドロゲルおよびその製造方法 | |
| CN120465196B (zh) | 可生物降解壳聚糖-聚硫辛酸复合膜及其制备方法和应用 | |
| Asman et al. | pH‐and temperature‐sensitive in vitro release of salicylic acid through poly (vinyl alcohol‐g‐acrylamide) membranes | |
| Port et al. | Development of sublingual films and electrospun nanofibers of pramipexole for the immediate relief of dyskinesias in Parkinson’s disease | |
| WO2024156642A1 (en) | Hydrogels containing atropine | |
| JPH0627068B2 (ja) | 経皮薬剤 |