BE533358A - - Google Patents
Info
- Publication number
- BE533358A BE533358A BE533358DA BE533358A BE 533358 A BE533358 A BE 533358A BE 533358D A BE533358D A BE 533358DA BE 533358 A BE533358 A BE 533358A
- Authority
- BE
- Belgium
- Prior art keywords
- semicarbazide
- water
- dichloroacetyl
- acetone
- alcohol
- Prior art date
Links
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000000155 melt Substances 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 4
- 150000004820 halides Chemical class 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 150000008064 anhydrides Chemical class 0.000 claims description 2
- 150000002148 esters Chemical class 0.000 claims description 2
- 239000012442 inert solvent Substances 0.000 claims description 2
- 150000007513 acids Chemical class 0.000 claims 3
- 150000003349 semicarbazides Chemical class 0.000 claims 1
- CSCPPACGZOOCGX-UHFFFAOYSA-N acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 35
- 238000009835 boiling Methods 0.000 description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- FBCCMZVIWNDFMO-UHFFFAOYSA-N dichloroacetyl chloride Chemical compound ClC(Cl)C(Cl)=O FBCCMZVIWNDFMO-UHFFFAOYSA-N 0.000 description 6
- 239000011541 reaction mixture Substances 0.000 description 6
- 238000001953 recrystallisation Methods 0.000 description 6
- 125000001424 substituent group Chemical group 0.000 description 5
- 238000000354 decomposition reaction Methods 0.000 description 4
- 238000002844 melting Methods 0.000 description 4
- AVKHCKXGKPAGEI-UHFFFAOYSA-N Phenicarbazide Chemical compound NC(=O)NNC1=CC=CC=C1 AVKHCKXGKPAGEI-UHFFFAOYSA-N 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 229960001206 PHENICARBAZIDE Drugs 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229910052736 halogen Inorganic materials 0.000 description 2
- 150000002367 halogens Chemical class 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- -1 nitro, amino Chemical group 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- 150000003512 tertiary amines Chemical class 0.000 description 2
- YXFVVABEGXRONW-UHFFFAOYSA-N toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 2
- CWLVXOXYLODUHV-UHFFFAOYSA-N (3-methylanilino)urea Chemical compound CC1=CC=CC(NNC(N)=O)=C1 CWLVXOXYLODUHV-UHFFFAOYSA-N 0.000 description 1
- SLXAVUNYRGGKFM-UHFFFAOYSA-N (3-nitroanilino)urea Chemical compound NC(=O)NNC1=CC=CC([N+]([O-])=O)=C1 SLXAVUNYRGGKFM-UHFFFAOYSA-N 0.000 description 1
- FLZJLXWMFXXIPE-UHFFFAOYSA-N (4-methoxyanilino)urea Chemical compound COC1=CC=C(NNC(N)=O)C=C1 FLZJLXWMFXXIPE-UHFFFAOYSA-N 0.000 description 1
- BNLXVFJINKTAST-UHFFFAOYSA-N (N-chloroanilino)urea Chemical compound NC(=O)NN(Cl)C1=CC=CC=C1 BNLXVFJINKTAST-UHFFFAOYSA-N 0.000 description 1
- SCQYFFYVHXLAQV-UHFFFAOYSA-N 2,2-dibromoacetyl bromide Chemical compound BrC(Br)C(Br)=O SCQYFFYVHXLAQV-UHFFFAOYSA-N 0.000 description 1
- JWBKFUKBVHLCIA-UHFFFAOYSA-N 4-(2-carbamoylhydrazinyl)benzoic acid Chemical compound NC(=O)NNC1=CC=C(C(O)=O)C=C1 JWBKFUKBVHLCIA-UHFFFAOYSA-N 0.000 description 1
- XLJMAIOERFSOGZ-UHFFFAOYSA-N 420-05-3 Chemical compound OC#N XLJMAIOERFSOGZ-UHFFFAOYSA-N 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- OWMRWRFYPHLYEF-UHFFFAOYSA-N [N+](=O)([O-])C=1C=C(C=CC=1)N(NC(=O)N)C(C(Cl)Cl)=O Chemical compound [N+](=O)([O-])C=1C=C(C=CC=1)N(NC(=O)N)C(C(Cl)Cl)=O OWMRWRFYPHLYEF-UHFFFAOYSA-N 0.000 description 1
- 125000004442 acylamino group Chemical group 0.000 description 1
- 125000005138 alkoxysulfonyl group Chemical group 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 description 1
- 125000004414 alkyl thio group Chemical group 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 230000000973 chemotherapeutic Effects 0.000 description 1
- 230000000875 corresponding Effects 0.000 description 1
- XLJMAIOERFSOGZ-UHFFFAOYSA-M cyanate Chemical compound [O-]C#N XLJMAIOERFSOGZ-UHFFFAOYSA-M 0.000 description 1
- 201000009910 diseases by infectious agent Diseases 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE533358A true BE533358A (no) |
Family
ID=165096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE533358D BE533358A (no) |
Country Status (1)
| Country | Link |
|---|---|
| BE (1) | BE533358A (no) |
-
0
- BE BE533358D patent/BE533358A/fr unknown
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