BE1011571A3 - Procede d'inhibition de la production cellulaire de cytokines. - Google Patents
Procede d'inhibition de la production cellulaire de cytokines. Download PDFInfo
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- BE1011571A3 BE1011571A3 BE9700949A BE9700949A BE1011571A3 BE 1011571 A3 BE1011571 A3 BE 1011571A3 BE 9700949 A BE9700949 A BE 9700949A BE 9700949 A BE9700949 A BE 9700949A BE 1011571 A3 BE1011571 A3 BE 1011571A3
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- OQJBFFCUFALWQL-UHFFFAOYSA-N n-(piperidine-1-carbonylimino)piperidine-1-carboxamide Chemical compound C1CCCCN1C(=O)N=NC(=O)N1CCCCC1 OQJBFFCUFALWQL-UHFFFAOYSA-N 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 238000012261 overproduction Methods 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 230000033116 oxidation-reduction process Effects 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 230000003169 placental effect Effects 0.000 description 1
- 229940068918 polyethylene glycol 400 Drugs 0.000 description 1
- 230000023603 positive regulation of transcription initiation, DNA-dependent Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001566 pro-viral effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 230000036303 septic shock Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 235000010215 titanium dioxide Nutrition 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE9700949A BE1011571A3 (fr) | 1997-11-26 | 1997-11-26 | Procede d'inhibition de la production cellulaire de cytokines. |
| US09/555,258 US6407081B1 (en) | 1997-11-26 | 1998-11-25 | Method for inhibiting cytokine production by cells |
| AU13276/99A AU757489B2 (en) | 1997-11-26 | 1998-11-25 | Method for inhibiting cytokine production by cells |
| JP2000522922A JP2001524526A (ja) | 1997-11-26 | 1998-11-25 | サイトカインの細胞生産を阻害するための方法 |
| PCT/BE1998/000183 WO1999027937A2 (fr) | 1997-11-26 | 1998-11-25 | Procede d'inhibition de la production cellulaire de cytokines |
| CA002312023A CA2312023A1 (fr) | 1997-11-26 | 1998-11-25 | Procede d'inhibition de la production cellulaire de cytokines |
| AT98956724T ATE290870T1 (de) | 1997-11-26 | 1998-11-25 | Verfahren zur hemmung der zellulären zytokinproduktion |
| DE69829406T DE69829406T2 (de) | 1997-11-26 | 1998-11-25 | Verfahren zur hemmung der zellulären zytokinproduktion |
| EP98956724A EP1032401B1 (fr) | 1997-11-26 | 1998-11-25 | Procede d'inhibition de la production cellulaire de cytokines |
| ES98956724T ES2241182T3 (es) | 1997-11-26 | 1998-11-25 | Procedimiento de inhibicion de la produccion de citocinas. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE9700949A BE1011571A3 (fr) | 1997-11-26 | 1997-11-26 | Procede d'inhibition de la production cellulaire de cytokines. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE1011571A3 true BE1011571A3 (fr) | 1999-11-09 |
Family
ID=3890860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE9700949A BE1011571A3 (fr) | 1997-11-26 | 1997-11-26 | Procede d'inhibition de la production cellulaire de cytokines. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6407081B1 (enExample) |
| EP (1) | EP1032401B1 (enExample) |
| JP (1) | JP2001524526A (enExample) |
| AT (1) | ATE290870T1 (enExample) |
| AU (1) | AU757489B2 (enExample) |
| BE (1) | BE1011571A3 (enExample) |
| CA (1) | CA2312023A1 (enExample) |
| DE (1) | DE69829406T2 (enExample) |
| ES (1) | ES2241182T3 (enExample) |
| WO (1) | WO1999027937A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE1011571A3 (fr) * | 1997-11-26 | 1999-11-09 | Hubriphar | Procede d'inhibition de la production cellulaire de cytokines. |
| AU2001245453B2 (en) * | 2000-03-14 | 2005-08-25 | National Jewish Medical And Research Center | Method and composition for treating airway hyperresponsiveness |
| AR058107A1 (es) * | 2005-10-26 | 2008-01-23 | Phar H | Azodicarbonamida micronizada, su preparacion y su utilizacion |
| EP2213299B1 (fr) | 2009-01-29 | 2015-09-09 | Michel Vandevelde | Composition vaccinale à base de virus exhibant une protéine à motif(s) en doigt de zinc, son procédé de préparation et son utilisation |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991016054A1 (fr) * | 1990-04-19 | 1991-10-31 | Previsan S.A. | Derives azoiques, compositions pharmaceutiques et desinfectantes les contenant et leurs utilisations contre le sida |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5585367A (en) | 1990-04-19 | 1996-12-17 | Previsan S.A. | Method of treating humans and animals infected with viruses of the retrovirus group |
| BE1011571A3 (fr) * | 1997-11-26 | 1999-11-09 | Hubriphar | Procede d'inhibition de la production cellulaire de cytokines. |
-
1997
- 1997-11-26 BE BE9700949A patent/BE1011571A3/fr not_active IP Right Cessation
-
1998
- 1998-11-25 DE DE69829406T patent/DE69829406T2/de not_active Expired - Lifetime
- 1998-11-25 AT AT98956724T patent/ATE290870T1/de not_active IP Right Cessation
- 1998-11-25 EP EP98956724A patent/EP1032401B1/fr not_active Expired - Lifetime
- 1998-11-25 ES ES98956724T patent/ES2241182T3/es not_active Expired - Lifetime
- 1998-11-25 AU AU13276/99A patent/AU757489B2/en not_active Ceased
- 1998-11-25 CA CA002312023A patent/CA2312023A1/fr not_active Abandoned
- 1998-11-25 US US09/555,258 patent/US6407081B1/en not_active Expired - Fee Related
- 1998-11-25 JP JP2000522922A patent/JP2001524526A/ja active Pending
- 1998-11-25 WO PCT/BE1998/000183 patent/WO1999027937A2/fr not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991016054A1 (fr) * | 1990-04-19 | 1991-10-31 | Previsan S.A. | Derives azoiques, compositions pharmaceutiques et desinfectantes les contenant et leurs utilisations contre le sida |
Non-Patent Citations (13)
| Title |
|---|
| A.K. SAMANTA ET AL.: "Modification of sulfhydryl groups of interleukin-8 (IL-8) receptor impairs binding of IL-8 and IL-8-mediated chemotactic response of human polymorphonuclear neutrophils", DIALOG(R) FILE 155: MEDLINE(R), ACCESSION NUMBER 07507394, J. BIOL. CHEM., vol. 268, no. 9, 25 March 1993 (1993-03-25), pages 6147 - 6153, XP002073575 * |
| C. MENDEZ ET AL.: "Oxidants augment endotoxin-induced activation of alveolar macrophages", DIALOG(R) FILE 155: MEDLINE(R), ACCESSION NUMBER 08881177, SHOCK, vol. 6, no. 3, September 1996 (1996-09-01), pages 157 - 163, XP002073572 * |
| J.C. NORMAND ET AL.: "Occupational asthma after exposure to azodicarbonamide: report of four cases", DIALOG(R) FILE 155: MEDLINE(R), ACCESSION NUMBER 05533800, BR. J. IND. MED., vol. 46, no. 1, January 1989 (1989-01-01), pages 60 - 62, XP002073577 * |
| K.KINOSHITA ET AL.: "Reducing environment protects sinusoidal lymphocytes isolated from normal human liver from apoptosis", DIALOG(R) FILE 155: MEDLINE(R), ACCESSION NUMBER 09003147, J. HEPATOL., vol. 26, no. 1, January 1997 (1997-01-01), pages 103 - 110, XP002073570 * |
| N. SATO ET AL.: "Thiol-mediated redox regulation of apoptosis. Possible roles of cellular thiols other than glutathione in T cell apoptosis", DIALOG(R) FILE 159: CANCERLIT, ACCESSION NUMBER 01125021, J. IMMUNOL., vol. 154, no. 7, 1995, pages 3194 - 3203, XP002073567 * |
| P. BRENNAN ET AL.: "Inhibition of NF kappa B activity by oxidative processes in intact cells mechanism of action of pyrolidine dithiocarbamate and diamide", DIALOG(R) FILE 155: MEDLINE(R), ACCESSION NUMBER 08615137, BIOCHEM. SOC. TRANS., vol. 24, no. 1, February 1996 (1996-02-01), pages 3S, XP002073573 * |
| P. BRENNAN ET AL.: "The effects of thiol modifiers on the activation of NF kappa B by interleukin-1", DIALOG(R) FILE 155: MEDLINE(R), ACCESSION NUMBER 07744657, BIOCHEM. SOC. TRANS., vol. 21, no. 4, November 1993 (1993-11-01), pages 390S, XP002073574 * |
| P. MARCHETTI ET AL.: "Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function", DIALOG(R) FILE 155: MEDLINE(R), ACCESSION NUMBER 08911997, EUR. J. IMMUNOL., vol. 27, no. 1, January 1997 (1997-01-01), pages 289 - 296, XP002073571 * |
| R.W. WATSON ET AL.: "Thiol-mediated redox regulation of neutrophil apoptosis", DIALOG(R) FILE 155: MEDLINE(R), ACCESSION NUMBER 09237740, SURGERY, vol. 120, no. 2, August 1996 (1996-08-01), pages 150 - 157, XP002073569 * |
| S. DHAWAN ET AL.: "Induction of endothelial cell surface adhesion molecules by tumor necrosis factor is blocked by protein tyrosine phosphatase inhibitors: role of the nuclear transcription factor NF-kappa B", DIALOG(R) FILE 155: MEDLINE(R), ACCESSION NUMBER 09294944, EUR. J. IMMUNOL., vol. 27, no. 9, September 1997 (1997-09-01), pages 2172 - 2179, XP002073568 * |
| S.SINGH ET AL.: "Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B", DIALOG(R) FILE 159: CANCERLIT, ACCESSION NUMBER 01132498, J BIOL CHEM, vol. 270, no. 18, 1995, pages 10631 - 10639, XP002073566 * |
| V.M.YATES ET AL.: "Contact dermatitis from azodicarbonamide in earplugs", DIALOG(R) FILE 155: MEDLINE(R), ACCESSION NUMBER 06072452, CONTACT DERMATITIS, vol. 19, no. 2, August 1988 (1988-08-01), pages 155 - 156, XP002073576 * |
| Y. MAKINO ET AL.: "Thioredoxin: a redox-regulating cellular cofactor for glucocorticoid hormone action. Cross talk between endocrine control of stress response and cellular antioxidant defense system", DIALOG(R) FILE 159: CANCERLIT, ACCESSION NUMBER 01283496, J. CLIN. INVEST., vol. 98, no. 11, 1996, pages 2469 - 2477, XP002073578 * |
Also Published As
| Publication number | Publication date |
|---|---|
| DE69829406D1 (de) | 2005-04-21 |
| CA2312023A1 (fr) | 1999-06-10 |
| WO1999027937A2 (fr) | 1999-06-10 |
| ATE290870T1 (de) | 2005-04-15 |
| EP1032401B1 (fr) | 2005-03-16 |
| US6407081B1 (en) | 2002-06-18 |
| ES2241182T3 (es) | 2005-10-16 |
| WO1999027937A3 (fr) | 1999-10-14 |
| DE69829406T2 (de) | 2006-03-02 |
| AU1327699A (en) | 1999-06-16 |
| AU757489B2 (en) | 2003-02-20 |
| EP1032401A2 (fr) | 2000-09-06 |
| JP2001524526A (ja) | 2001-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: HUBRIPHAR Effective date: 19991130 |