BE1003227A3 - Tripeptides utiles comme immunostimulants de meme que dans la prevention des metastases. - Google Patents
Tripeptides utiles comme immunostimulants de meme que dans la prevention des metastases. Download PDFInfo
- Publication number
- BE1003227A3 BE1003227A3 BE8800895A BE8800895A BE1003227A3 BE 1003227 A3 BE1003227 A3 BE 1003227A3 BE 8800895 A BE8800895 A BE 8800895A BE 8800895 A BE8800895 A BE 8800895A BE 1003227 A3 BE1003227 A3 BE 1003227A3
- Authority
- BE
- Belgium
- Prior art keywords
- immunostimulants
- metastases
- prevention
- well
- tripeptides
- Prior art date
Links
- 206010027476 Metastases Diseases 0.000 title 1
- 229960001438 immunostimulant agent Drugs 0.000 title 1
- 239000003022 immunostimulating agent Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- CKLJMWTZIZZHCS-UHFFFAOYSA-N D-OH-Asp Chemical group OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 abstract 1
- ODKSFYDXXFIFQN-SCSAIBSYSA-N D-arginine Chemical group OC(=O)[C@H](N)CCCNC(N)=N ODKSFYDXXFIFQN-SCSAIBSYSA-N 0.000 abstract 1
- CKLJMWTZIZZHCS-UWTATZPHSA-N D-aspartic acid Chemical group OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 abstract 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical group OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical group OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
- 230000002001 anti-metastasis Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 229940124280 l-arginine Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21575/87A IT1222437B (it) | 1987-08-04 | 1987-08-04 | Tripeptidi utili come immunostimolanti e nella prevenzione delle metastasi e relativo procedimento di preparazione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE1003227A3 true BE1003227A3 (fr) | 1992-02-04 |
Family
ID=11183828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE8800895A BE1003227A3 (fr) | 1987-08-04 | 1988-08-02 | Tripeptides utiles comme immunostimulants de meme que dans la prevention des metastases. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4929601A (cg-RX-API-DMAC7.html) |
| JP (1) | JPS6463593A (cg-RX-API-DMAC7.html) |
| AT (1) | ATA195788A (cg-RX-API-DMAC7.html) |
| BE (1) | BE1003227A3 (cg-RX-API-DMAC7.html) |
| CH (1) | CH678059A5 (cg-RX-API-DMAC7.html) |
| DE (1) | DE3826595C2 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2621317B1 (cg-RX-API-DMAC7.html) |
| GB (1) | GB2207922B (cg-RX-API-DMAC7.html) |
| GR (1) | GR1000339B (cg-RX-API-DMAC7.html) |
| IE (1) | IE60870B1 (cg-RX-API-DMAC7.html) |
| IT (1) | IT1222437B (cg-RX-API-DMAC7.html) |
| NL (1) | NL8801932A (cg-RX-API-DMAC7.html) |
| SE (1) | SE8802790L (cg-RX-API-DMAC7.html) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4156490A (en) * | 1976-05-25 | 1979-05-29 | Prot S.R.L. | Method of hermetically sealing soft-drink bottles and like containers |
| US5827821A (en) | 1987-12-10 | 1998-10-27 | The Burnham Institute | Conformationally stabilized cell adhesion peptides |
| DE3855458T2 (de) * | 1987-12-10 | 1996-12-05 | Jolla Cancer Res Found | Verfahren zur herstellung von conformationnell stabilisierten zelladhäsionspeptiden |
| CA1324954C (en) * | 1988-03-10 | 1993-12-07 | Erkki I. Ruoslahti | Inhibition of cell migration with synthetic peptides |
| US5236903A (en) * | 1988-06-24 | 1993-08-17 | Ichiro Azuma | Polypeptide comprising repeated cell-adhesive core sequences |
| JP2625156B2 (ja) * | 1988-06-24 | 1997-07-02 | 市郎 東 | 細胞接着活性コア配列の繰り返し構造からなるポリペプチド |
| IT1226552B (it) * | 1988-07-29 | 1991-01-24 | Ellem Ind Farmaceutica | Peptidi immunostimolanti. |
| US5843897A (en) * | 1989-06-16 | 1998-12-01 | Cor Therapeutics, Inc. | Platelet aggregation inhibitors |
| US5795868A (en) * | 1989-06-16 | 1998-08-18 | Cor Therapeutics, Inc. | Platelet aggregation inhibitors |
| US5318899A (en) * | 1989-06-16 | 1994-06-07 | Cor Therapeutics, Inc. | Platelet aggregation inhibitors |
| US5384309A (en) * | 1989-07-17 | 1995-01-24 | Genentech, Inc. | Cyclized peptides and their use as platelet aggregation inhibitors |
| US5780303A (en) * | 1990-04-06 | 1998-07-14 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
| ES2104702T3 (es) * | 1990-04-06 | 1997-10-16 | Jolla Cancer Res Found | Metodo y composicion para el tratamiento de la trombosis. |
| US5612311A (en) | 1990-04-06 | 1997-03-18 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
| US5648330A (en) * | 1990-04-06 | 1997-07-15 | La Jolla Cancer Research Foundation | Method and composition for treating vascular graft occlusion |
| US6521594B1 (en) | 1990-04-06 | 2003-02-18 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
| US5672585A (en) * | 1990-04-06 | 1997-09-30 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
| US5264420A (en) * | 1990-09-27 | 1993-11-23 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| AU9131091A (en) * | 1990-11-07 | 1992-06-11 | Scripps Research Institute, The | Peptides that inhibit platelet binding of adhesion molecules |
| CA2106314A1 (en) * | 1991-04-05 | 1992-10-06 | John P. Burnier | Platelet aggregation inhibitors having high specification for gpiibiiia |
| HUT63609A (en) * | 1992-03-10 | 1993-09-28 | Sandoz Ag | Process for producing new derivatives and isosters of beta-amino acids and pharmaceutical compositions comprising such compounds |
| US5639729A (en) * | 1993-08-26 | 1997-06-17 | Immunobiology Research Institute, Inc. | Tripeptides useful in immune and CNS therapy |
| ATE350389T1 (de) | 2003-05-08 | 2007-01-15 | Pentapharm Ag | Tripeptide und deren derivate für die kosmetische verwendung zur verbesserung der hautstruktur |
| RU2301074C1 (ru) * | 2006-05-30 | 2007-06-20 | Общество С Ограниченной Ответственностью "Сиа Пептайдс" | Пептид, обладающий иммуногеропротекторным действием, фармацевтическая композиция на его основе и способ ее применения |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743590A (en) * | 1978-07-31 | 1988-05-10 | Debarbieri Augusto | In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound |
| US4508710A (en) * | 1978-07-31 | 1985-04-02 | Proter S.P.A. | In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound |
| HU185263B (en) * | 1981-06-12 | 1984-12-28 | Richter Gedeon Vegyeszet | Process for producing peptides effective on the immuncontroll analogous with the tp5 |
| FR2569111B1 (fr) * | 1984-08-16 | 1987-04-17 | Rhone Poulenc Sante | Nouveaux medicaments contenant des tripeptides |
-
1987
- 1987-08-04 IT IT21575/87A patent/IT1222437B/it active
-
1988
- 1988-08-02 US US07/227,356 patent/US4929601A/en not_active Expired - Fee Related
- 1988-08-02 CH CH2918/88A patent/CH678059A5/it not_active IP Right Cessation
- 1988-08-02 BE BE8800895A patent/BE1003227A3/fr not_active IP Right Cessation
- 1988-08-02 SE SE8802790A patent/SE8802790L/ not_active Application Discontinuation
- 1988-08-03 AT AT0195788A patent/ATA195788A/de not_active Application Discontinuation
- 1988-08-03 IE IE236688A patent/IE60870B1/en not_active IP Right Cessation
- 1988-08-03 GB GB8818447A patent/GB2207922B/en not_active Expired - Fee Related
- 1988-08-03 NL NL8801932A patent/NL8801932A/nl not_active Application Discontinuation
- 1988-08-03 FR FR888810487A patent/FR2621317B1/fr not_active Expired - Fee Related
- 1988-08-03 GR GR880100509A patent/GR1000339B/el unknown
- 1988-08-04 DE DE3826595A patent/DE3826595C2/de not_active Expired - Fee Related
- 1988-08-04 JP JP63197020A patent/JPS6463593A/ja active Pending
Non-Patent Citations (2)
| Title |
|---|
| J. EXP. MED., vol. 162, août 1985, pages 762-767, The Rockefeller University Press; S.D. WRIGHT et al.: "Fibronectin receptor of human macrophages recognizes the sequence Arg-Gly-Asp-Ser" * |
| PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES USA, vol. 82, septembre 1985, pages 5766-5770; R. PYTELA et al.: "A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin" * |
Also Published As
| Publication number | Publication date |
|---|---|
| CH678059A5 (cg-RX-API-DMAC7.html) | 1991-07-31 |
| US4929601A (en) | 1990-05-29 |
| IE882366L (en) | 1989-02-04 |
| IE60870B1 (en) | 1994-08-24 |
| SE8802790D0 (sv) | 1988-08-02 |
| DE3826595A1 (de) | 1989-02-16 |
| GR1000339B (el) | 1992-06-25 |
| GR880100509A (en) | 1989-05-25 |
| GB8818447D0 (en) | 1988-09-07 |
| GB2207922B (en) | 1991-02-20 |
| FR2621317B1 (fr) | 1994-06-17 |
| IT1222437B (it) | 1990-09-05 |
| IT8721575A0 (it) | 1987-08-04 |
| FR2621317A1 (fr) | 1989-04-07 |
| SE8802790L (sv) | 1989-02-05 |
| DE3826595C2 (de) | 1994-02-17 |
| JPS6463593A (en) | 1989-03-09 |
| NL8801932A (nl) | 1989-03-01 |
| ATA195788A (de) | 1996-05-15 |
| GB2207922A (en) | 1989-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: ELLEM INDUSTRIA FARMACEUTICA S.P.A. Effective date: 19960831 |