AU8023500A - System and method for detecting and identifying molecular events in a test sample - Google Patents

System and method for detecting and identifying molecular events in a test sample

Info

Publication number
AU8023500A
AU8023500A AU80235/00A AU8023500A AU8023500A AU 8023500 A AU8023500 A AU 8023500A AU 80235/00 A AU80235/00 A AU 80235/00A AU 8023500 A AU8023500 A AU 8023500A AU 8023500 A AU8023500 A AU 8023500A
Authority
AU
Australia
Prior art keywords
test
signal
fluid
response
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU80235/00A
Other languages
English (en)
Inventor
Barrett J. Bartell
Robert G. Chapman
John J. Hefti
Mark A. Rhodes
Min Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MDS SCIEX
Original Assignee
Signature Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Signature Bioscience Inc filed Critical Signature Bioscience Inc
Publication of AU8023500A publication Critical patent/AU8023500A/en
Assigned to MDS SCIEX reassignment MDS SCIEX Alteration of Name(s) of Applicant(s) under S113 Assignors: SIGNATURE BIOSCIENCE INC.
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0673Handling of plugs of fluid surrounded by immiscible fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0645Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0418Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electro-osmotic flow [EOF]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N22/00Investigating or analysing materials by the use of microwaves or radio waves, i.e. electromagnetic waves with a wavelength of one millimetre or more
AU80235/00A 1999-10-13 2000-10-13 System and method for detecting and identifying molecular events in a test sample Abandoned AU8023500A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15917599P 1999-10-13 1999-10-13
US60159175 1999-10-13
US19170200P 2000-03-23 2000-03-23
US60191702 2000-03-23
PCT/US2000/028491 WO2001027610A2 (en) 1999-10-13 2000-10-13 System and method for detecting and identifying molecular events in a test sample

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2005203756A Division AU2005203756A1 (en) 1999-10-13 2005-08-19 System and method for detecting and identifying molecular events in a test sample

Publications (1)

Publication Number Publication Date
AU8023500A true AU8023500A (en) 2001-04-23

Family

ID=26855720

Family Applications (3)

Application Number Title Priority Date Filing Date
AU80235/00A Abandoned AU8023500A (en) 1999-10-13 2000-10-13 System and method for detecting and identifying molecular events in a test sample
AU2005203756A Abandoned AU2005203756A1 (en) 1999-10-13 2005-08-19 System and method for detecting and identifying molecular events in a test sample
AU2008203111A Abandoned AU2008203111A1 (en) 1999-10-13 2008-07-14 System and method for detecting and identifying molecular events in a test sample

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2005203756A Abandoned AU2005203756A1 (en) 1999-10-13 2005-08-19 System and method for detecting and identifying molecular events in a test sample
AU2008203111A Abandoned AU2008203111A1 (en) 1999-10-13 2008-07-14 System and method for detecting and identifying molecular events in a test sample

Country Status (10)

Country Link
EP (1) EP1224453A2 (no)
JP (1) JP2003535310A (no)
KR (1) KR20020071853A (no)
CN (1) CN1425133A (no)
AU (3) AU8023500A (no)
CA (1) CA2386193A1 (no)
IL (1) IL149001A0 (no)
MX (1) MXPA02003815A (no)
NO (1) NO20021687L (no)
WO (1) WO2001027610A2 (no)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586946B2 (en) 2000-11-13 2003-07-01 Signature Bioscience, Inc. System and method for detecting and identifying molecular events in a test sample using a resonant test structure
WO2002066983A2 (en) * 2001-02-01 2002-08-29 Signature Bioscience, Inc. Bioassay device for detecting molecular events
US20020168659A1 (en) * 2001-02-12 2002-11-14 Signature Bioscience Inc. System and method for characterizing the permittivity of molecular events
GB0117715D0 (en) * 2001-07-19 2001-09-12 Mrbp Res Ltd Microwave biochemical analysis
US7670770B2 (en) 2001-07-25 2010-03-02 The Trustees Of Princeton University Nanochannel arrays and their preparation and use for high throughput macromolecular analysis
US9678038B2 (en) 2001-07-25 2017-06-13 The Trustees Of Princeton University Nanochannel arrays and their preparation and use for high throughput macromolecular analysis
US20030032000A1 (en) * 2001-08-13 2003-02-13 Signature Bioscience Inc. Method for analyzing cellular events
KR100537504B1 (ko) 2003-01-20 2005-12-19 삼성전자주식회사 생물학적 시료 내에서의 단백질 검출을 위한 자동화된 유동 시스템
GB0328054D0 (en) * 2003-12-04 2004-01-07 Council Cent Lab Res Councils Fluid probe
GB0605273D0 (en) * 2006-03-16 2006-04-26 Council Cent Lab Res Councils Fluid robe
US10746680B2 (en) * 2006-11-16 2020-08-18 General Electric Company Sensing system and method
EP2136922B1 (en) 2007-03-28 2012-12-05 BioNano Genomics, Inc. Methods of macromolecular analysis using nanochannel arrays
GB0716202D0 (en) * 2007-08-11 2007-09-26 Microvisk Ltd Improved fluid probe
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9567631B2 (en) 2012-12-14 2017-02-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10221442B2 (en) 2012-08-14 2019-03-05 10X Genomics, Inc. Compositions and methods for sample processing
CA3216609A1 (en) 2012-08-14 2014-02-20 10X Genomics, Inc. Microcapsule compositions and methods
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10400280B2 (en) 2012-08-14 2019-09-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
GB201219016D0 (en) * 2012-10-23 2012-12-05 Liverpool John Moores University Electromagnetic wave sensing
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9791453B2 (en) * 2012-12-26 2017-10-17 International Business Machines Corporation Methods for determining binding capability of target ligands with G protein-coupled receptors using translocation through nanochannels
WO2014124338A1 (en) 2013-02-08 2014-08-14 10X Technologies, Inc. Polynucleotide barcode generation
JP6625519B2 (ja) * 2013-03-15 2019-12-25 イナノベイト, インコーポレイテッド アッセイシステムおよびカートリッジデバイス
CN111662960B (zh) 2013-06-25 2024-04-12 普罗格诺西斯生物科学公司 采用微流控装置的空间编码生物分析
US9255321B2 (en) 2013-10-15 2016-02-09 Globalfoundries Inc. Directed surface functionalization on selected surface areas of topographical features with nanometer resolution
US9303310B2 (en) 2013-10-15 2016-04-05 International Business Machines Corporation Nanofluidic sensor comprising spatially separated functional sensing components
US10024851B2 (en) 2013-10-15 2018-07-17 International Business Machines Corporation Use of disulfide bonds to form a reversible and reusable coating for nanofluidic devices
CN114534806B (zh) 2014-04-10 2024-03-29 10X基因组学有限公司 用于封装和分割试剂的流体装置、系统和方法及其应用
US9921181B2 (en) 2014-06-26 2018-03-20 International Business Machines Corporation Detection of translocation events using graphene-based nanopore assemblies
WO2015200893A2 (en) 2014-06-26 2015-12-30 10X Genomics, Inc. Methods of analyzing nucleic acids from individual cells or cell populations
MX2017005267A (es) 2014-10-29 2017-07-26 10X Genomics Inc Metodos y composiciones para la secuenciacion de acidos nucleicos seleccionados como diana.
US9975122B2 (en) 2014-11-05 2018-05-22 10X Genomics, Inc. Instrument systems for integrated sample processing
TWI569017B (zh) * 2014-11-14 2017-02-01 Nippon Mektron Kk Coaxial probe holding mechanism and electrical characteristics check device
KR102321863B1 (ko) 2015-01-12 2021-11-08 10엑스 제노믹스, 인크. 핵산 시퀀싱 라이브러리의 제조 방법 및 시스템 및 이를 이용하여 제조한 라이브러리
EP4286516A3 (en) 2015-02-24 2024-03-06 10X Genomics, Inc. Partition processing methods and systems
AU2016222719B2 (en) 2015-02-24 2022-03-31 10X Genomics, Inc. Methods for targeted nucleic acid sequence coverage
EP4151748B1 (en) 2015-04-10 2023-12-20 10x Genomics Sweden AB Spatially distinguished, multiplex nucleic acid analysis of biological specimens
SG10202108763UA (en) 2015-12-04 2021-09-29 10X Genomics Inc Methods and compositions for nucleic acid analysis
ES2809127T3 (es) * 2015-12-23 2021-03-03 Viking Genetics Fmba Sistema RFID para identificación de pajillas criogénicas
WO2017197338A1 (en) 2016-05-13 2017-11-16 10X Genomics, Inc. Microfluidic systems and methods of use
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
CN117512066A (zh) 2017-01-30 2024-02-06 10X基因组学有限公司 用于基于微滴的单细胞条形编码的方法和系统
EP4230746A3 (en) 2017-05-26 2023-11-01 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
US20180340169A1 (en) 2017-05-26 2018-11-29 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
SG11201913654QA (en) 2017-11-15 2020-01-30 10X Genomics Inc Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
CN108257052B (zh) * 2018-01-16 2022-04-22 中南大学 一种在线学生知识评估方法及其系统
EP3775271A1 (en) 2018-04-06 2021-02-17 10X Genomics, Inc. Systems and methods for quality control in single cell processing
CN109192250B (zh) * 2018-08-01 2021-12-07 华东理工大学 一种多相催化中克服表面物种快速迁移的加速模拟方法
WO2021236929A1 (en) 2020-05-22 2021-11-25 10X Genomics, Inc. Simultaneous spatio-temporal measurement of gene expression and cellular activity
CN115598464A (zh) * 2022-10-08 2023-01-13 金华乐馨发制品有限公司(Cn) 一种电缆末端高低压电路的检测和修复装置及其方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0519250A3 (en) * 1991-06-10 1993-06-02 Miles Inc. Microparticle-labeled binding assay analyzed by microwave spectroscopy
WO1995003542A1 (en) * 1993-07-26 1995-02-02 Phase Dynamics, Inc. System and method for monitoring substances and reactions
SE9700828D0 (sv) * 1997-03-07 1997-03-07 Asea Brown Boveri Förfarande och anordning för att bestämma ett flertal kvalitetsparametrar vilka beskriver tillståndet hos ett organiskt material
EP0991938B1 (en) * 1998-02-02 2004-06-30 MDS Sciex Method and apparatus for detecting molecular binding events

Also Published As

Publication number Publication date
JP2003535310A (ja) 2003-11-25
WO2001027610A9 (en) 2002-08-01
KR20020071853A (ko) 2002-09-13
MXPA02003815A (es) 2002-09-30
WO2001027610A2 (en) 2001-04-19
CN1425133A (zh) 2003-06-18
NO20021687D0 (no) 2002-04-10
EP1224453A2 (en) 2002-07-24
WO2001027610A3 (en) 2002-03-28
IL149001A0 (en) 2002-11-10
AU2005203756A1 (en) 2005-09-15
NO20021687L (no) 2002-06-12
AU2008203111A1 (en) 2008-08-07
CA2386193A1 (en) 2001-04-19

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