AU784755B2 - Daptomycin Analogs as antibacterial agents - Google Patents

Daptomycin Analogs as antibacterial agents Download PDF

Info

Publication number
AU784755B2
AU784755B2 AU22682/01A AU2268201A AU784755B2 AU 784755 B2 AU784755 B2 AU 784755B2 AU 22682/01 A AU22682/01 A AU 22682/01A AU 2268201 A AU2268201 A AU 2268201A AU 784755 B2 AU784755 B2 AU 784755B2
Authority
AU
Australia
Prior art keywords
alkyl
group
compound
heterocyclyl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU22682/01A
Other languages
English (en)
Other versions
AU2268201A (en
Inventor
Dale Christensen
John Finn
Jason Hill
Dennis Keith
Tsvetelina Lazarova
Michael Morytko
Ian Parr
Jim Siedlecki
Jared Silverman
Alan D. Watson
Xiang Yang Yu
Yan Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Cubist Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cubist Pharmaceuticals LLC filed Critical Cubist Pharmaceuticals LLC
Publication of AU2268201A publication Critical patent/AU2268201A/en
Application granted granted Critical
Publication of AU784755B2 publication Critical patent/AU784755B2/en
Assigned to MERCK SHARP & DOHME CORP. reassignment MERCK SHARP & DOHME CORP. Alteration of Name(s) in Register under S187 Assignors: CUBIST PHARMACEUTICALS, INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU22682/01A 1999-12-15 2000-12-15 Daptomycin Analogs as antibacterial agents Ceased AU784755B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17094399P 1999-12-15 1999-12-15
US60/170943 1999-12-15
PCT/US2000/034118 WO2001044272A2 (en) 1999-12-15 2000-12-15 Daptomycin analogs as antibacterial agents

Publications (2)

Publication Number Publication Date
AU2268201A AU2268201A (en) 2001-06-25
AU784755B2 true AU784755B2 (en) 2006-06-08

Family

ID=22621910

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22682/01A Ceased AU784755B2 (en) 1999-12-15 2000-12-15 Daptomycin Analogs as antibacterial agents

Country Status (13)

Country Link
US (2) US6911525B2 (enExample)
EP (4) EP2298790A1 (enExample)
JP (2) JP4990456B2 (enExample)
KR (1) KR20020063227A (enExample)
CN (1) CN1425025A (enExample)
AU (1) AU784755B2 (enExample)
BR (1) BR0017026A (enExample)
CA (1) CA2393907A1 (enExample)
IL (2) IL150223A0 (enExample)
MX (1) MXPA02006029A (enExample)
NO (1) NO20022888L (enExample)
WO (1) WO2001044272A2 (enExample)
ZA (1) ZA200205106B (enExample)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1423656A (zh) * 1999-12-15 2003-06-11 卡比斯特制药公司 作为抗菌剂的脂肽
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
CA2301336A1 (en) * 2000-03-17 2001-09-17 Michael T. Kelly Topical treatment of rosacea
KR20090122469A (ko) 2000-12-18 2009-11-30 큐비스트 파마슈티컬즈 인코포레이티드 정제된 리포펩티드의 제조 방법
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
EP1932853A1 (en) 2001-08-06 2008-06-18 Cubist Pharmaceutical Inc. Novel depsipeptides and process for preparing same
EP1423137B1 (en) * 2001-08-06 2009-04-29 Cubist Pharmaceuticals, Inc. Lipopeptide stereoisomers, methods for preparing same, and useful intermediates
ES2243763T3 (es) * 2001-08-28 2005-12-01 Pharmacia Corporation Base libre de clindamicina cristalina.
US6767718B2 (en) 2002-05-10 2004-07-27 Biosource Pharm, Inc. Lipodepsipeptide antibiotics and methods of preparation
AU2003265241A1 (en) * 2002-05-23 2003-12-12 Activbiotics, Inc. Methods of treating bacterial infections and diseases associated therewith
CA2488803C (en) 2002-06-06 2013-08-13 Vicuron Pharmaceuticals Inc. Use of ramoplanin to treat diseases associated with the use of antibiotics
IL150907A (en) * 2002-07-25 2007-07-04 Stephan Cherkez Process for the preparation of stable amorphous calcium pseudomonate
ITMI20022076A1 (it) * 2002-10-01 2004-04-02 Antibioticos Spa Sali di intermedi del cefdinir.
US20040132764A1 (en) * 2002-10-23 2004-07-08 Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie Antibiotics for the treatment of infections in acidic environments
US20060004185A1 (en) 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
JP2008519848A (ja) * 2004-11-12 2008-06-12 キュービスト ファーマシューティカルズ， インコーポレイテッド 抗感染性リポペプチド
US20080051326A1 (en) * 2004-11-12 2008-02-28 Alexander Dylan C Antiinfective Lipopeptides
CA2606386C (en) * 2005-04-29 2014-06-10 Cubist Pharmaceuticals, Inc. Therapeutic compositions
US20100227918A1 (en) * 2006-04-26 2010-09-09 Taro Pharmaceuticals North America, Inc. Streptomyces-derived antimicrobial compound and method of using same against antibiotic-resistant bacteria
JP5345532B2 (ja) * 2006-08-02 2013-11-20 ヨハネス・グーテンベルク−ウニヴェルジテート・マインツ Ｌｃｔ中毒に対する医薬品
US8662086B2 (en) 2007-02-06 2014-03-04 BBK Tobacco & Foods, LLP Reclosable package with magnetic clasp for rolling papers used in smoking articles
US20080185010A1 (en) * 2007-02-06 2008-08-07 Kesselman Joshua D Interleaved Transparent Cellulose Paper with Opaque Adhesive
US8584854B2 (en) * 2007-02-06 2013-11-19 BBK Tobacco & Foods, LLP Reclosable package with magnetic clasp and detachable tray for rolling papers used in smoking articles
US20090020443A1 (en) * 2007-05-09 2009-01-22 Kesselman Joshua D Credit Card Carrying Pack for Rolling Papers
US9072319B2 (en) 2007-06-15 2015-07-07 Joshua D. Kesselman Rolling paper structures for creating smoking articles and gummed, coiled inserts for same
US9161572B2 (en) * 2007-06-15 2015-10-20 Bbk Tobacco & Foods, Inc. Structures for creating smoking articles and methods of packaging same
US20090014342A1 (en) * 2007-07-14 2009-01-15 Kesselman Joshua D Rolling papers and methods of packaging same
EP2018864A1 (en) 2007-07-23 2009-01-28 Biomet Deutschland GmbH Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition
CN101959849A (zh) * 2007-12-26 2011-01-26 利德治疗公司 作为抗菌剂的新型半合成糖肽
USD606858S1 (en) 2008-08-21 2009-12-29 Joshua Kesselman Packaging for smoking articles
US8393332B2 (en) 2008-08-21 2013-03-12 BBK Tobacco & Foods, LLP Packaging for rolling papers for smoking articles
GB2465863A (en) * 2008-12-05 2010-06-09 Lead Therapeutics Inc Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections
DK2379580T3 (da) * 2008-12-22 2014-01-20 Cubist Pharm Inc Hidtil ukendte antibakterielle midler til behandling af gram-positive infektioner
AR074874A1 (es) 2008-12-23 2011-02-16 Biosource Pharm Inc Composiciones antibioticas para el tratamiento de infecciones gram negativas. metodo. uso. compuesto.
ES2374779B1 (es) * 2010-03-10 2012-12-27 Universidad De Barcelona Compuestos péptidicos útiles como agentes antibacterianos.
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
WO2012011917A1 (en) * 2010-07-23 2012-01-26 Activbiotics Pharma, Llc Administration of rifalazil to immunocompromised patients
US10072045B1 (en) 2017-06-26 2018-09-11 Ramapo Pharmaceuticals, Inc. Antibacterial lipopeptides and methods for their preparation and use
US10526343B2 (en) 2018-03-26 2020-01-07 University Of Sharjah Heterocyclic systems and pharmaceutical applications thereof
CN110577581A (zh) * 2018-06-07 2019-12-17 美国蓝博药业公司 一种新型的抑菌脂肽化合物、制备方法及其应用
CN109182563B (zh) * 2018-08-01 2020-07-14 浙江大学 检测20种dfrA类甲氧苄胺嘧啶类药物耐药基因的方法及所用试剂盒
CN113061164B (zh) * 2021-03-29 2023-01-10 四川大学 环脂肽类化合物及其在抗类风湿关节炎药物中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0095295A1 (en) * 1982-05-21 1983-11-30 Eli Lilly And Company Cyclic peptide derivatives

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854480A (en) 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
USRE32455E (en) 1978-10-16 1987-07-07 Eli Lilly And Company A-21978 antibiotics and process for their production
USRE32333E (en) 1978-10-16 1987-01-20 Eli Lilly And Company A-21978 Antibiotics and process for their production
CA1195983A (en) 1982-02-27 1985-10-29 Graham Walker Antibacterial 1-normon-2-yl thiazoles and - oxazoles
US4482487A (en) 1982-05-21 1984-11-13 Eli Lilly And Company A-21978C cyclic peptides
USRE32311E (en) 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4537717A (en) * 1982-05-21 1985-08-27 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4396543A (en) 1982-05-21 1983-08-02 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
USRE32310E (en) 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4399067A (en) 1982-05-21 1983-08-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4524135A (en) 1982-05-21 1985-06-18 Eli Lilly And Company A-21978C cyclic peptides
US4452775A (en) 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
US4885243A (en) 1984-10-09 1989-12-05 Eli Lilly And Company Process for producing A-21978C derivatives
DD238068A5 (de) 1984-10-09 1986-08-06 ���@�����@�K@�������k�� Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c
US4874843A (en) 1987-12-03 1989-10-17 Eli Lilly And Company Chromatographic purification process
CA1315229C (en) 1987-06-10 1993-03-30 Eli Lilly And Company Chromatographic purification process
EP0460882B1 (en) 1990-06-07 1996-07-24 Eli Lilly And Company Lipopeptide deacylase
JPH04167172A (ja) 1990-10-31 1992-06-15 Nec Corp ベクトルプロセッサ
JPH09504512A (ja) 1993-08-13 1997-05-06 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 抗菌活性、抗マイコプラズマ活性、抗真菌類活性および除草活性を有するモン酸ａおよびｃの誘導体
DE4411025A1 (de) 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
EP1854877B1 (en) 1996-03-08 2012-02-08 Astellas Pharma Inc. Process for the deacylation of cyclic lipopeptides
DE19807972A1 (de) 1998-02-25 1999-08-26 Hoechst Marion Roussel De Gmbh Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
DK1115417T3 (da) 1998-09-25 2006-07-31 Cubist Pharm Inc Anvendelse af daptomycin
US9393093B2 (en) 2008-02-18 2016-07-19 Covidien Lp Clip for implant deployment device
KR20220135825A (ko) 2021-03-31 2022-10-07 에스케이하이닉스 주식회사 반도체 장치 제조 방법

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0095295A1 (en) * 1982-05-21 1983-11-30 Eli Lilly And Company Cyclic peptide derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF ANTIBIOTICS (1988), 1093-1105 *

Also Published As

Publication number Publication date
WO2001044272A2 (en) 2001-06-21
US20050203006A1 (en) 2005-09-15
EP2295444A2 (en) 2011-03-16
EP1884520A3 (en) 2008-03-05
JP4990456B2 (ja) 2012-08-01
EP1240181A2 (en) 2002-09-18
NO20022888D0 (no) 2002-06-17
KR20020063227A (ko) 2002-08-01
CA2393907A1 (en) 2001-06-21
IL150223A0 (en) 2002-12-01
JP2003517004A (ja) 2003-05-20
US7335725B2 (en) 2008-02-26
US6911525B2 (en) 2005-06-28
EP1884520A2 (en) 2008-02-06
AU2268201A (en) 2001-06-25
EP2298790A1 (en) 2011-03-23
NO20022888L (no) 2002-08-02
BR0017026A (pt) 2003-01-07
US20020025924A1 (en) 2002-02-28
EP2295444A3 (en) 2011-03-23
JP2012140432A (ja) 2012-07-26
IL150223A (en) 2013-09-30
CN1425025A (zh) 2003-06-18
WO2001044272A3 (en) 2001-11-29
ZA200205106B (en) 2003-09-25
MXPA02006029A (es) 2004-08-23

Similar Documents

Publication Publication Date Title
AU784942B2 (en) Daptomycin analogs and their use as antibacterial agents
US20020025924A1 (en) Novel lipopeptides as antibacterial agents
AU784812B2 (en) Lipopeptides as antibacterial agents
US20080119395A1 (en) Novel Depsipeptides and Process for Preparing Same
CA2747965A1 (en) Novel antibacterial agents for the treatment of gram positive infections
HK1156040A (en) Lipopeptides as antibacterial agents
HK1112926A (en) Daptomycin analogs as antibacterial agents
HK1155465A (en) Daptomycin analogs as antibacterial agents
EP1932853A1 (en) Novel depsipeptides and process for preparing same

Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired