AU781376B2 - Telomerase-specific cancer vaccine - Google Patents

Telomerase-specific cancer vaccine Download PDF

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Publication number
AU781376B2
AU781376B2 AU41394/00A AU4139400A AU781376B2 AU 781376 B2 AU781376 B2 AU 781376B2 AU 41394/00 A AU41394/00 A AU 41394/00A AU 4139400 A AU4139400 A AU 4139400A AU 781376 B2 AU781376 B2 AU 781376B2
Authority
AU
Australia
Prior art keywords
telomerase
antigen
cytokine
protein
length
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU41394/00A
Other languages
English (en)
Other versions
AU4139400A (en
Inventor
Babita Agrawal
Bryan Michael Longenecker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncothyreon Canada Inc
Original Assignee
Biomira Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomira Inc filed Critical Biomira Inc
Publication of AU4139400A publication Critical patent/AU4139400A/en
Application granted granted Critical
Publication of AU781376B2 publication Critical patent/AU781376B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/462Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622Antigen presenting cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643Vertebrate antigens
    • A61K39/4644Cancer antigens
    • A61K39/464454Enzymes
    • A61K39/464457Telomerase or [telomerase reverse transcriptase [TERT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07Nucleotidyltransferases (2.7.7)
    • C12Y207/07049RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU41394/00A 1999-04-09 2000-04-07 Telomerase-specific cancer vaccine Ceased AU781376B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12853999P 1999-04-09 1999-04-09
US60/128539 1999-04-09
PCT/IB2000/000610 WO2000061766A2 (fr) 1999-04-09 2000-04-07 Vaccin anticancereux specifique de la telomerase

Publications (2)

Publication Number Publication Date
AU4139400A AU4139400A (en) 2000-11-14
AU781376B2 true AU781376B2 (en) 2005-05-19

Family

ID=22435817

Family Applications (1)

Application Number Title Priority Date Filing Date
AU41394/00A Ceased AU781376B2 (en) 1999-04-09 2000-04-07 Telomerase-specific cancer vaccine

Country Status (5)

Country Link
EP (1) EP1171612A2 (fr)
JP (1) JP2002541811A (fr)
AU (1) AU781376B2 (fr)
CA (1) CA2368967A1 (fr)
WO (1) WO2000061766A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7585622B1 (en) 1996-10-01 2009-09-08 Geron Corporation Increasing the proliferative capacity of cells using telomerase reverse transcriptase
AU734089B2 (en) 1996-10-01 2001-06-07 Geron Corporation Human telomerase catalytic subunit
US7622549B2 (en) 1997-04-18 2009-11-24 Geron Corporation Human telomerase reverse transcriptase polypeptides
US7413864B2 (en) 1997-04-18 2008-08-19 Geron Corporation Treating cancer using a telomerase vaccine
US7402307B2 (en) 1998-03-31 2008-07-22 Geron Corporation Method for identifying and killing cancer cells
CA2347067C (fr) * 1998-03-31 2013-09-17 Geron Corporation Vaccin a base de cellule dendritique contenant de la transcriptase inverse de la telomarase pour le traitement du cancer
EP1257284A4 (fr) * 2000-02-15 2005-12-21 Univ California Vaccin universel et methode de traitement du cancer utilisant la transcriptase inverse de la telomerase
JP2004527449A (ja) 2000-02-15 2004-09-09 リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア テロメラーゼ逆転写酵素を用いる癌を治療するための万能ワクチンと方法
GB0031430D0 (en) 2000-12-22 2001-02-07 Norsk Hydro As Polypeptides
JP2005525992A (ja) * 2001-06-25 2005-09-02 イサム・リサーチ・デベロツプメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシテイ・オブ・エルサレム 生物学的物質を充填した小胞の調製法およびそれらの様々な使用
DE102006025146A1 (de) * 2006-05-30 2007-12-06 Charité - Universitätsmedizin Berlin Peptide zur differentiellen Modulation der proteasomalen Aktivität
EP1887084A1 (fr) 2006-08-10 2008-02-13 International Investment and Patents SA Plasmides avec l'action immunologique
WO2014079464A1 (fr) * 2012-11-21 2014-05-30 Sherif Salah Abdul Aziz Nouvelles compositions enzymatiques pour le traitement d'une infection par le virus de l'immunodéficience humaine (vih)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3456099A (en) * 1998-03-31 1999-10-18 Geron Corporation Methods and compositions for eliciting an immune response to a telomerase antigen
AU4534099A (en) * 1998-07-08 2000-02-01 Gemvax As Antigenic peptides derived from telomerase

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU734089B2 (en) * 1996-10-01 2001-06-07 Geron Corporation Human telomerase catalytic subunit
ATE394474T1 (de) * 1997-05-08 2008-05-15 Biomira Inc Verfahren zur gewinnung von aktivierten t-zellen und mit antigen inkubierten antigenpräsentierenden zellen
EP1126872B1 (fr) * 1998-10-29 2006-12-13 Dana-Farber Cancer Institute, Inc. IMMUNOTHERAPIE ET DIAGNOSTIC DU CANCER AU MOYEN D'ANTIGENES UNIVERSELS ASSOCIES A DES TUMEURS TELS QUE hTERT

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3456099A (en) * 1998-03-31 1999-10-18 Geron Corporation Methods and compositions for eliciting an immune response to a telomerase antigen
AU4534099A (en) * 1998-07-08 2000-02-01 Gemvax As Antigenic peptides derived from telomerase

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VONDERHEIDE ET AL.(1998)BLOOD 92(10)SUPPL.1 PART 1-2,P500A *

Also Published As

Publication number Publication date
EP1171612A2 (fr) 2002-01-16
WO2000061766A2 (fr) 2000-10-19
WO2000061766A3 (fr) 2001-03-08
JP2002541811A (ja) 2002-12-10
CA2368967A1 (fr) 2000-10-19
AU4139400A (en) 2000-11-14

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