AU780444B2 - Chlamydia antigens and corresponding DNA fragments and uses thereof - Google Patents
Chlamydia antigens and corresponding DNA fragments and uses thereof Download PDFInfo
- Publication number
- AU780444B2 AU780444B2 AU43885/00A AU4388500A AU780444B2 AU 780444 B2 AU780444 B2 AU 780444B2 AU 43885/00 A AU43885/00 A AU 43885/00A AU 4388500 A AU4388500 A AU 4388500A AU 780444 B2 AU780444 B2 AU 780444B2
- Authority
- AU
- Australia
- Prior art keywords
- ala
- polypeptide
- ser
- seq
- gin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/295—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Otolaryngology (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13227099P | 1999-05-03 | 1999-05-03 | |
| US60/132270 | 1999-05-03 | ||
| US14127699P | 1999-06-30 | 1999-06-30 | |
| US60/141276 | 1999-06-30 | ||
| PCT/CA2000/000511 WO2000066739A2 (en) | 1999-05-03 | 2000-05-03 | Chlamydia antigens and corresponding dna fragments and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU4388500A AU4388500A (en) | 2000-11-17 |
| AU780444B2 true AU780444B2 (en) | 2005-03-24 |
Family
ID=26830227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU43885/00A Ceased AU780444B2 (en) | 1999-05-03 | 2000-05-03 | Chlamydia antigens and corresponding DNA fragments and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20030095973A1 (https=) |
| EP (1) | EP1177301B1 (https=) |
| JP (1) | JP4695763B2 (https=) |
| AT (1) | ATE375391T1 (https=) |
| AU (1) | AU780444B2 (https=) |
| CA (1) | CA2373021A1 (https=) |
| DE (1) | DE60036698T2 (https=) |
| WO (1) | WO2000066739A2 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1105489A1 (en) | 1998-08-20 | 2001-06-13 | Aventis Pasteur Limited | Nucleic acid molecules encoding pomp91a protein of chlamydia |
| WO2000011181A1 (en) | 1998-08-20 | 2000-03-02 | Connaught Laboratories Limited | NUCLEIC ACID MOLECULES ENCODING INCLUSION MEMBRANE PROTEIN C OF $i(CHLAMYDIA) |
| US6686339B1 (en) | 1998-08-20 | 2004-02-03 | Aventis Pasteur Limited | Nucleic acid molecules encoding inclusion membrane protein C of Chlamydia |
| US6649370B1 (en) | 1998-10-28 | 2003-11-18 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US6607730B1 (en) | 1998-11-02 | 2003-08-19 | Aventis Pasteur Limited/Aventis Pasteur Limitee | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| CA2353107A1 (en) | 1998-12-01 | 2000-06-08 | Andrew D. Murdin | Chlamydia antigens and corresponding dna fragments and uses thereof |
| EP1169465B1 (en) * | 1998-12-04 | 2006-03-01 | University Of Manitoba | Two-step immunization procedure against chlamydia infection |
| US20020061848A1 (en) | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
| JP2002531129A (ja) | 1998-12-08 | 2002-09-24 | コリクサ コーポレイション | クラミジア感染の処置および診断のための化合物および方法 |
| GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
| US7297341B1 (en) | 1998-12-23 | 2007-11-20 | Sanofi Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| CA2354431A1 (en) * | 1998-12-23 | 2000-07-06 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| JP2002541766A (ja) | 1998-12-28 | 2002-12-10 | アベンティス、パストゥール、リミテッド | クラミジア抗原および対応するdna断片ならびにその使用 |
| US6808713B1 (en) | 1998-12-28 | 2004-10-26 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| GB9902555D0 (en) | 1999-02-05 | 1999-03-24 | Neutec Pharma Plc | Medicament |
| MXPA01009256A (es) | 1999-03-12 | 2003-07-14 | Aventis Pasteur | Antigenos de chlamydia y fragmentos de acido desoxirribonucleico correspondientes y usos de los mismos. |
| DE60036698T2 (de) | 1999-05-03 | 2008-07-24 | Sanofi Pasteur Ltd., Toronto | Chlamydia-antigene und entsprechende dna-fragmente und deren verwendungen |
| NZ517952A (en) | 1999-09-20 | 2004-01-30 | Aventis Pasteur | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US6632663B1 (en) | 1999-09-22 | 2003-10-14 | Aventis Pasteur Limited | DNA immunization against chlamydia infection |
| AU1375501A (en) * | 1999-11-12 | 2001-05-30 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| EP1240331B1 (en) | 1999-12-22 | 2010-04-07 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| US20020082402A1 (en) * | 2000-04-04 | 2002-06-27 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| WO2001081379A2 (en) | 2000-04-21 | 2001-11-01 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| AU2001258105A1 (en) | 2000-05-08 | 2001-11-20 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| US20040254130A1 (en) * | 2000-05-08 | 2004-12-16 | Murdin Andrew D | Chlamydia antigens and corresponding dna fragments and uses thereof |
| JP2004502415A (ja) | 2000-07-03 | 2004-01-29 | カイロン エセ.ピー.アー. | Chlamydiapneumoniaeに対する免疫化 |
| US20080112965A1 (en) * | 2001-10-01 | 2008-05-15 | Aventis Pasteur Limited | Chlamydia OMP antigen |
| US8568732B2 (en) | 2009-03-06 | 2013-10-29 | Novartis Ag | Chlamydia antigens |
| WO2011063133A1 (en) | 2009-11-18 | 2011-05-26 | Auburn University | LOW ANTIGEN-DOSE IMMUNIZATION FOR MAXIMIZING T-HELPER CELL 1 (T h1) IMMUNITY AGAINST DISEASE |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1331443C (en) * | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
| US5283185A (en) * | 1991-08-28 | 1994-02-01 | University Of Tennessee Research Corporation | Method for delivering nucleic acids into cells |
| DE69535914D1 (de) * | 1994-09-20 | 2009-03-26 | Hitachi Chemical Co Ltd | Polynukleotide die einen antigenes polypeptid aus chlamydia pneumoniae kodieren |
| FR2726764B1 (fr) * | 1994-11-14 | 1997-01-31 | Pasteur Merieux Serums Vacc | Adjuvant pour composition vaccinale |
| US5840788A (en) | 1997-06-20 | 1998-11-24 | Acushnet Company | Ultraviolet light resistant urethane top coat for golf balls |
| JP4160640B2 (ja) * | 1997-06-23 | 2008-10-01 | スヴェンド バークランド | クラミジア・ニューモニエ由来の表面露出タンパク質 |
| US7459524B1 (en) * | 1997-10-02 | 2008-12-02 | Emergent Product Development Gaithersburg Inc. | Chlamydia protein, sequence and uses thereof |
| DE69841894D1 (de) | 1997-11-21 | 2010-10-21 | Merck Serono Biodevelopment Sa | Äusseres Membranpolypeptid von Chlamydia pneumoniae sowie Fragmente davon und deren Verwendung, insbesondere zur Diagnose, Prävention und Behandlung einer Infektion |
| JP2002536958A (ja) * | 1997-11-21 | 2002-11-05 | ジェンセット | Chlamydiapneumoniaeゲノム配列およびポリペプチド、それらのフラグメント、ならびに特に感染症の診断、予防および治療のためのそれらの使用 |
| EP2218731A1 (en) | 1997-11-28 | 2010-08-18 | Merck Serono Biodevelopment | Chlamydia trachomatis genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection |
| WO2000011181A1 (en) | 1998-08-20 | 2000-03-02 | Connaught Laboratories Limited | NUCLEIC ACID MOLECULES ENCODING INCLUSION MEMBRANE PROTEIN C OF $i(CHLAMYDIA) |
| US6693087B1 (en) | 1998-08-20 | 2004-02-17 | Aventis Pasteur Limited | Nucleic acid molecules encoding POMP91A protein of Chlamydia |
| MXPA01004291A (es) | 1998-10-28 | 2003-06-09 | Aventis Pasteur | Antigenos de chlamydia y fragmentos de acido desoxirribonucleico correspondientes y usos de los mismos. |
| US6822071B1 (en) * | 1998-11-12 | 2004-11-23 | The Regents Of The University Of California | Polypeptides from Chlamydia pneumoniae and their use in the diagnosis, prevention and treatment of disease |
| CA2350775A1 (en) | 1998-11-12 | 2000-05-18 | The Regents Of The University Of California | Chlamydia pneumoniae genome sequence |
| CA2353107A1 (en) | 1998-12-01 | 2000-06-08 | Andrew D. Murdin | Chlamydia antigens and corresponding dna fragments and uses thereof |
| JP2002531129A (ja) | 1998-12-08 | 2002-09-24 | コリクサ コーポレイション | クラミジア感染の処置および診断のための化合物および方法 |
| US6565856B1 (en) | 1998-12-08 | 2003-05-20 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US20020061848A1 (en) | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
| GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
| US6808713B1 (en) | 1998-12-28 | 2004-10-26 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| GB9902555D0 (en) | 1999-02-05 | 1999-03-24 | Neutec Pharma Plc | Medicament |
| DE60036698T2 (de) | 1999-05-03 | 2008-07-24 | Sanofi Pasteur Ltd., Toronto | Chlamydia-antigene und entsprechende dna-fragmente und deren verwendungen |
| NZ517952A (en) | 1999-09-20 | 2004-01-30 | Aventis Pasteur | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US6632663B1 (en) | 1999-09-22 | 2003-10-14 | Aventis Pasteur Limited | DNA immunization against chlamydia infection |
| EP1240331B1 (en) | 1999-12-22 | 2010-04-07 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| AU2138501A (en) | 1999-12-22 | 2001-07-03 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20020071831A1 (en) | 2000-04-04 | 2002-06-13 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20030100706A1 (en) | 2000-04-04 | 2003-05-29 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20020082402A1 (en) | 2000-04-04 | 2002-06-27 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20020132994A1 (en) | 2000-04-04 | 2002-09-19 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20020094965A1 (en) | 2000-04-04 | 2002-07-18 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| WO2001081379A2 (en) | 2000-04-21 | 2001-11-01 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US20040254130A1 (en) | 2000-05-08 | 2004-12-16 | Murdin Andrew D | Chlamydia antigens and corresponding dna fragments and uses thereof |
| AU2001258105A1 (en) | 2000-05-08 | 2001-11-20 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| JP2004502415A (ja) | 2000-07-03 | 2004-01-29 | カイロン エセ.ピー.アー. | Chlamydiapneumoniaeに対する免疫化 |
-
2000
- 2000-05-03 DE DE60036698T patent/DE60036698T2/de not_active Expired - Lifetime
- 2000-05-03 WO PCT/CA2000/000511 patent/WO2000066739A2/en not_active Ceased
- 2000-05-03 CA CA002373021A patent/CA2373021A1/en not_active Abandoned
- 2000-05-03 JP JP2000615762A patent/JP4695763B2/ja not_active Expired - Fee Related
- 2000-05-03 AT AT00925004T patent/ATE375391T1/de active
- 2000-05-03 AU AU43885/00A patent/AU780444B2/en not_active Ceased
- 2000-05-03 US US09/564,479 patent/US20030095973A1/en not_active Abandoned
- 2000-05-03 EP EP00925004A patent/EP1177301B1/en not_active Expired - Lifetime
-
2003
- 2003-06-30 US US10/608,559 patent/US7070792B2/en not_active Expired - Fee Related
-
2005
- 2005-05-02 US US11/118,381 patent/US7595058B2/en not_active Expired - Fee Related
-
2009
- 2009-02-09 US US12/367,955 patent/US7658934B2/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
|---|
| MELGOSA INFECT. IMMUN. 1994 62(3):880-86 * |
| TREMB AC. NO. Q927H7 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU4388500A (en) | 2000-11-17 |
| WO2000066739A2 (en) | 2000-11-09 |
| EP1177301A2 (en) | 2002-02-06 |
| CA2373021A1 (en) | 2000-11-09 |
| US7070792B2 (en) | 2006-07-04 |
| JP4695763B2 (ja) | 2011-06-08 |
| JP2002542827A (ja) | 2002-12-17 |
| US7658934B2 (en) | 2010-02-09 |
| EP1177301B1 (en) | 2007-10-10 |
| US20040086525A1 (en) | 2004-05-06 |
| WO2000066739A3 (en) | 2001-01-11 |
| US20090155350A1 (en) | 2009-06-18 |
| ATE375391T1 (de) | 2007-10-15 |
| US7595058B2 (en) | 2009-09-29 |
| US20030095973A1 (en) | 2003-05-22 |
| US20050202048A1 (en) | 2005-09-15 |
| DE60036698D1 (de) | 2007-11-22 |
| DE60036698T2 (de) | 2008-07-24 |
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